Pch2 links chromatin silencing to meiotic checkpoint control

Cell

Volumn 97, Issue 3, 1999, Pages 313-324

  San Segundo, Pedro A ^a   Shirleen Roeder, G ^a,b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOSOME DNA;

ARTICLE; CELL DIVISION; CHROMATIN STRUCTURE; CHROMOSOME SEGREGATION; CYTOLOGY; GENE ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENETIC RECOMBINATION; GENETIC SCREENING; MEIOSIS; MODEL; NONHUMAN; PACHYTENE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE; SPOROGENESIS;

SACCHAROMYCES CEREVISIAE;

EID: 0033617290     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80741-2     Document Type: Article

References (49)

1. Beyer, A. (1997). Sequence analysis of the AAA protein family. Prot. Sci. 6, 2043-2058.
2. Bishop, D., Park, D., Xu, L., and Kleckner, N. (1992). DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69, 439-456.
3. Bryk, M., Banerjee, M., Murphy, M., Knudsen, K.E., Garfinkel, D.J., and Curcio, M.J. (1997). Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev. 11, 255-269.
4. Burns, N., Grimwade, B., Ross-Macdonald, P.B., Choi, E.-Y., Finberg, K., Roeder, G.S., and Snyder, M. (1994). Large-scale analysis of gene expression, protein localization and gene disruption in Saccharomyces cerevisiae. Genes Dev. 8, 1087-1105.
5. Cao, L., Alani, E., and Kleckner, N. (1990). A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae. Cell 61, 1089-1101.
6. Chien, C.-t., Buck, S., Sternglanz, R., and Shore, D. (1993). Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast. Cell 75, 531-541.
7. Christianson, T.W., Sikorski, R.S., Dante, M., Shero, J.H., and Hieter, P. (1992). Multifunctional yeast high-copy-number shuttle vectors. Gene 110, 119-122.
8. Chua, P.R., and Roeder, G.S. (1998). Zip2, a meiosis-specific protein required for the initiation of chromosome synapsis. Cell 93, 349-359.
9. Cockell, M., Palladino, F., Laroche, T., Kyrion, G., Liu, C., Lustig, A.J., and Gasser, S.M. (1995). The carboxi termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing. J. Cell Biol. 129, 909-924.
10. Dresser, M.E., and Giroux, C.N. (1988). Meiotic chromosome behavior in spread preparations of yeast. J. Cell Biol. 106, 567-578.
11. Edelmann, W., Cohen, P.E., Kane, M., Lau, K., Morrow, B., Bennett, S., Umar, A., Kunkel, T., Cattoretti, G., Chaganti, R., et al. (1996). Meiotic pachytene arrest in MLH1-deficient mice. Cell 85, 1125-1134.
12. Engebrecht, J., and Roeder, G.S. (1989). Yeast men mutants display reduced levels of meiotic recombination. Genetics 121, 237-247.
13. Fritze, C.E., Verschueren, K., Strich, R., and Esposito, R.E. (1997). Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA. EMBO J. 76, 6495-6509.
14. Gotta, M., Strahl-Bolsinger, S., Renauld, H., Laroche, T., Kennedy, B.K., Grunstein, M., and Gasser, S.M. (1997). Localization of Sir2p: the nucleolus as a compartment for silent information regulators. EMBO J. 16, 3243-3255.
15. Gottlieb, S., and Esposito, R.E. (1989). A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA. Cell 56, 771-776.
16. Guarente, L. (1997). Link between aging and the nucleolus. Genes Dev. 11, 2449-2455.
17. Hartwell, L.H., and Weinert, T.A. (1989). Checkpoints: controls that ensure the order of cell cycle events. Science 246, 629-634.
18. Hollingsworth, N.M., and Byers, B. (1989). HOP1: a yeast meiotic pairing gene. Genetics 121, 445-462.
19. Hollingsworth, N.M., Goetsch, L., and Byers, B. (1990). The HOP1 gene encodes a meiosis-specific component of yeast chromosomes. Cell 61, 73-84.
20. Ivy, J.M., Klar, A.J.S., and Hicks, J.B. (1986). Cloning and characterization of four SIR genes of Saccharomyces cerevisiae. Mol. Cell. Biol. 6, 688-702.
21. Leu, J.-Y., Chua, P.R., and Roeder, G.S. (1998). The meiosis-specific Hop2 protein of S. cerevisiae ensures synapsis between homologous chromosomes. Cell 94, 375-386.
22. Loidl, J., Klein, F., and Scherthan, H. (1994). Homologous pairing is reduced but not abolished in asynaptic mutants of yeast. J. Cell Biol. 125, 1191-1200.
23. Loo, S., and Rine, J. (1995). Silencing and heritable domains of gene expression. Annu. Rev. Cell. Dev. Biol. 11, 519-548.
24. Lydall, D., Nikolsky, Y., Bishop, D.K., and Weinert, T. (1996). A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383, 840-843.
25. McKee, A.H. Z., and Kleckner, N. (1997). Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3. Genetics 146, 817-834.
26. Mitchell, A.P. (1994). Control of meiotic gene expression in Saccharomyces cerevisiae. Microbiol. Rev. 58, 56-70.
27. Nierras, C.R., Liebman, S.W., and Warner, J.R. (1997). Does Saccharomyces need an organized nucleolus? Chromosoma 105, 444-451.
28. Pederson, T. (1998a). Growth factors in the nucleolus? J. Cell Biol. 143, 279-281.
29. Pederson, T. (1998b). The plurifunctional nucleolus. Nucleic Acids Res. 26, 3871-3876.
30. Petes, T.D., and Botstein, D. (1977). Simple mendelian inheritance of the reiterated ribosomal DNA of yeast. Proc. Natl. Acad. Sci. USA 74, 5091-5095.
31. Pittman, D.L., Cobb, J., Schimenti, K.J., Wilson, L.A., Cooper, D.M., Brignull, E., Handel, M.A., and Schimenti, J.C. (1998). Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog. Mol. Cell 1, 697-705.
32. Rockmill, B., Sym, M., Scherthan, H., and Roeder, G.S. (1995). Roles for two RecA homologs in promoting meiotic chromosome synapsis. Genes Dev. 9, 2684-2695.
33. Roeder, G.S. (1997). Meiotic chromosomes: it takes two to tango. Genes Dev. D11, 2600-2621.
34. Santos, B., and Snyder, M. (1997). Targeting of chitin synthase 3 to polarized growth sites in yeast requires Chs5p and Myo2p. J. Cell Biol. 136, 95-110.
35. Schneider, B.L., Seufert, W., Steiner, B., Yang, Q.H., and Futcher, A.B. (1995). Use of polymerase chain reaction epitope tagging for protein tagging in Saccharomyces cerevisiae. Yeast 11, 1265-1274.
36. Singer, M.S., Kahana, A., Wolf, A.J., Meisinger, L.L., Peterson, S.E., Coggin, C., Mahowald, M., and Gottschling, D.E. (1998). Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150, 613-632.
37. Smith, J.S., and Boeke, J.D. (1997). An unusual form of transcriptional silencing in yeast ribosomal RNA. Genes Dev. 11, 241-254.
38. Smith, A.V., and Roeder, G.S. (1997). The yeast Red1 protein localizes to the cores of meiotic chromosomes. J. Cell Biol. 136, 957-967.
39. Smith, J.S., Brachmann, C.B., Pillus, L., and Boeke, J.D. (1998). Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p. Genetics 149, 1205-1219.
40. Stone, E.M., Swanson, M.J., Romeo, A.M., Hicks, J.B., and Sternglanz, R. (1991). The SIR1 gene of Saccharomyces cervisiae and its role as an extragenic suppressor of several mating-defective mutants. Mol. Cell. Biol. 11, 2253-2262.
41. Storlazzi, A., Xu, L., Schwacha, A., and Kleckner, N. (1996). Synaptonemal complex (SC) component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc. Natl. Acad. Sci. USA 93, 9043-9048.
42. Strahl-Bolsinger, S., Hecht, A., Luo, K., and Grunstein, M. (1997). SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11, 83-93.
43. Sym, M., and Roeder, G.S. (1994). Crossover interference is abolished in the absence of a synaptonemal complex protein. Cell 79, 283-292.
44. Sym, M., and Roeder, G.S. (1995). Zip1-induced changes in synaptonemal complex structure and polycomplex assembly. J. Cell Biol. 128, 455-466.
45. Sym, M., Engebrecht, J., and Roeder, G.S. (1993). ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis. Cell 72, 365-378.
46. Tsukamoto, Y., Kato, J.-I., and Ikeda, H. (1997). Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature 388, 900-903.
47. Tung, K.S., and Roeder, G.S. (1998). Meiotic chromosome morphology and behavior in zip1 mutants of Saccharomyces cerevisiae. Genetics 149, 817-832.
48. Weinert, T. (1998). DNA damage and checkpoint pathways: molecular anatomy and interactions with repair. Cell 94, 555-558.
49. Yoshida, K., Kondoh, G., Matsuda, Y., Habu, T., Nishimune, Y., and Morita, T. (1998). The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis. Mol. Cell 1, 707-718.