Formation of Fe(III)Fe(IV) species from the reaction between a diiron(II) complex and dioxygen: Relevance to ribonucleotide reductase intermediate X [12]

Journal of the American Chemical Society

Volumn 121, Issue 42, 1999, Pages 9893-9894

  Lee, Dongwhan ^a   Du Bois, J ^a   Petasis, Doros ^b   Hendrich, Michael P ^b   Krebs, Carsten ^c   Huynh, Boi Hanh ^c   Lippard, Stephen J ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID; FERROUS ION; IRON COMPLEX; OXYGEN; RIBONUCLEOTIDE REDUCTASE;

CHEMICAL REACTION; CHEMICAL STRUCTURE; COMPLEX FORMATION; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; LETTER; MOSSBAUER SPECTROSCOPY;

EID: 0033610489     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9923686     Document Type: Letter

References (23)

1. Lee, D.; Lippard, S. J. J. Am. Chem. Soc. 1998, 120, 12153-12154.
2. (a) Feig, A. L.; Lippard, S. J. Chem. Rev. 1994, 94, 759-805.
3. (b) Wallar, B. J.; Lipscomb, J. D. Chem. Rev. 1996, 96, 2625-2657.
4. (c) Valentine, A. M.; Lippard, S. J. J. Chem. Soc., Dalton Trans. 1997, 3925-3931.
5. (d) Que, L., Jr. J. Chem. Soc., Dalton Trans. 1997, 3933-3940.
6. Riggs-Gelasco, P. J.; Shu, L.; Chen, S.; Burdi, D.; Huynh, B. H.; Que, L., Jr.; Stubbe, J. J. Am. Chem. Soc. 1998, 120, 849-860.
7. Stubbe, J.; van der Donk, W. A. Chem. Rev. 1998, 98, 705-762.
8. 2 at low temperature: (a) Dong, Y.; Fujii, H.; Hendrich, M. P.; Leising, R. A.; Pan, G.; Randall, C. R.; Wilkinson, E. C.; Zang, Y.; Que, L., Jr.; Fox, B. G.; Kauffmann, K.; Münck, E. J. Am. Chem. Soc. 1995, 117, 2778-2792.
9. (b) Dong, Y.; Que, L., Jr.; Kauffmann, K.; Münck, E. J. Am. Chem. Soc. 1995, 117, 11377-11378.
10. (c) Hsu, H.-F., Dong, Y.; Shu, L.; Young, V. G., Jr.; Que, L., Jr. J. Am. Chem. Soc. 1999, 121, 5230-5237.
11. Randall, C. R.; Shu, L.; Chiou, Y.-M.; Hagen, K. S.; Ito, M.; Kitajima, N.; Lachicotte, R. J.; Zang, Y.; Que, L., Jr. Inorg. Chem. 1995, 34, 1036-1039.
12. 2.
13. Burdi, D.; Sturgeon, B. E.; Tong, W. H.; Stubbe, J.; Hoffman, B. M. J. Am. Chem. Soc. 1996, 118, 281-282.
14. Sturgeon, B. E.; Burdi, D.; Chen, S.; Huynh, B. H.; Edmondson, D. E.; Stubbe, J.; Hoffman, B. M. J. Am. Chem. Soc. 1996, 118, 7551-7557.
15. The resonances near g = 4 in Q-band for both parallel and perpendicular modes are from an intradoublet transition and are not included in the simulation. The g = 19 (X-band) and possibly the g = 29 (Q-band) signals are from the diiron(III) species, whereas the g = 16 signal (Q-band) and its simulation are from unreacted 2, which account for 20 and 10% of the total iron, respectively.
16. Lee, D.; Lippard, S. J., manuscript in preparation.
17. Münck, E.; Papaefthymiou, V.; Surerus, K. K.; Girerd, J.-J. Metal Clusters in Proteins; Que, L., Jr., Ed.; American Chemical Society: Washington, D. C., 1988; pp 302-325.
18. III species, detailed characterization of which is currently in progress.
19. Valentine, A. M.; Tavares, P.; Pereira, A. S.; Davydov, R.; Krebs, C.; Hoffman, B. M.; Edmondson, D. E.; Huynh, B. H.; Lippard, S. J. J. Am. Chem. Soc. 1998, 120, 2190-2191.
20. IV species or in a branching pathway involving 2 and dioxygen.
21. 2: Miller, M. A.; Gobena, F. T.; Kauffmann, K.; Münck, E.; Que, L., Jr.; Stankovich, M. T. J. Am. Chem. Soc. 1999, 121, 1096-1097.
22. The oxidizing ability of 3 was manifested by reactions with substituted phenols, 2,4,6-tri-tert-butylphenol or 2,4-di-tert-butylphenol, which provided the corresponding phenoxyl radical (10%) or biphenol coupled product (40%), respectively. Unpublished results.
23. -1 in the resonance Raman spectrum: Hagadorn, J. R.; Que, L., Jr.; Tolman, W. B. J. Am. Chem. Soc. 1998, 120, 13531-13532.