Insulin-induced desensitization of extracellular signal-regulated kinase activation results from an inhibition of Raf activity independent of Ras activation and dissociation of the Grb2-SOS complex

Journal of Biological Chemistry

Volumn 274, Issue 26, 1999, Pages 18651-18658

  Fucini, Raymond V ^a   Okada, Shuichi ^a   Pessin, Jeffrey E ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN; RAS PROTEIN;

ANIMAL CELL; ARTICLE; DESENSITIZATION; DISSOCIATION; ENZYME ACTIVATION; ENZYME REGULATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CHO CELLS; CRICETINAE; ENZYME ACTIVATION; GRB2 ADAPTOR PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INSULIN; MACROMOLECULAR SUBSTANCES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-RAF; RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RAS PROTEINS; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA;

EID: 0033603324     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.26.18651     Document Type: Article

References (56)

1. Jans, D. A., and Hassan, G. (1998) BioEssays 20, 400-411
2. Porter, A. C., and Vaillancourt, R. R. (1998) Oncogene 17, 1343-1352
3. White, M. F., and Yenush, L. (1998) Curr. Top. Microbiol. Immunol. 228, 179-208
4. Avruch, J. (1998) Mol. Cell. Biochem. 182, 31-48
5. Skolnik, E. Y., Batzer, A., Li, N., Lee, C. H., Lowenstein, E., Mohammadi, M., Margolis, B., and Schlessinger, J. (1993) Science 260, 1953-1955
6. Downward, J. (1994) FEBS Lett. 338, 113-117
7. Songyang, Z., Shoelson, S. E., McGlade, J., Olivier, P., Pawson, T., Bustelo, X. R., Barbacid, M., Sabe, H., Hanafusa, H., Yi, T., Ren, R., Baltimore, D., Ratnofsky, S., Feldman, R. A., and Cantley, L. C. (1994) Mol. Cell. Biol. 14, 2777-2785
8. Chardin, P., Camonis, J. H., Gale, N. W., van Aelst, L., Schlessinger, J., Wigler, M. H., and Bar-Sagi, D. (1993) Science 260, 1338-1343
9. Egan, S. E., Giddings, B. W., Brooks, M. W., Buday, L., Sizeland, A. M., and Weinberg, R. A. (1993) Nature 363, 45-51
10. Li, N., Batzer, A., Daly, R., Yajnik, V., Skolnik, E., Chardin, P., Bar-Sagi, D., Margolis, B., and Schlessinger, J. (1993) Nature 363, 85-88
11. Lowenstein, E. J., Daly, R. J., Batzer, A. G., Li, W., Margolis, B., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar-Sagi, D., and Schlessinger, J. (1992) Cell 70, 431-442
12. Baltensperger, K., Kozma, L. M., Cherniack, A. D., Klarlund, J. K., Chawla, A., Banerjee, U., and Czech, M. P. (1993) Science 260, 1950-1952
13. Ouwens, D. M., van der Zon, G. C., Pronk, G. J., Bos, J. L., Moller, W., Cheatham, B., Kahn, C. R., and Maassen, J. A. (1994) J. Biol. Chem. 269, 33116-33122
14. Pronk, G. J., de Vries-Smits, A. M., Buday, L., Downward, J., Maassen, J. A., Medema, R. H., and Bos, J. L. (1994) Mol. Cell. Biol. 14, 1575-1581
15. Rozakis-Adcock, M., McGlade, J., Mbamalu, G., Pelicci, G., Daly, R., Li, W., Batzer, A., Thomas, S., Brugge, J., Pelicci, P. G., Schlessinger, J., and Pawson, T. (1992) Nature 360, 689-692
16. Waters, S. B., Yamauchi, K., and Pessin, J. E. (1993) J. Biol. Chem. 268, 22231-22234
17. Vojtek, A. B., Hollenberg, S. M., and Cooper, J. A. (1993) Cell 74, 205-214
18. Warne, P. H., Viciana, P. R., and Downward, J. (1993) Nature 364, 352-355
19. Yuryev, A., and Wennogle, L. P. (1998) Cell Res. 8, 81-98
20. Robinson, M. J., and Cobb, M. H. (1997) Curr. Opin. Cell Biol. 9, 180-186
21. Karlovich, C. A., Bonfini, L., McCollam, L., Rogge, R. D., Daga, A., Czech, M. P., and Banerjee, U. (1995) Science 268, 576-579
22. Aronheim, A., Engelberg, D., Li, N., Al-Alawi, N., Schlessinger, J., and Karin, M. (1994) Cell 78, 949-961
23. McCollam, L., Bonfini, L., Karlovich, C. A., Conway, B. R., Kozma, L. M., Banerjee, U., and Czech, M. P. (1995) J. Biol. Chem. 270, 15954-15957
24. Qian, X., Vass, W. C., Papageorge, A. G., Anborgh, P. H., and Lowy, D. R. (1998) Mol. Cell. Biol. 18, 771-778
25. Wang, W., Fisher, E. M., Jia, Q., Dunn, J. M., Porfiri, E., Downward, J., and Egan, S. E. (1995) Nat. Genet. 10, 294-300
26. Clark, S. G., Stern, M. J., and Horvitz, H. R. (1992) Nature 356, 340-344
27. Langlois, W. J., Sasaoka, T., Saltiel, A. R., and Olefsky, J. M. (1995) J. Biol. Chem. 270, 25320-25323
28. Cherniack, A. D., Klarlund, J. K., Conway, B. R., and Czech, M. P. (1995) J. Biol. Chem. 270, 1485-1488
29. Waters, S. B., Yamauchi, K., and Pessin, J. E. (1995) Mol. Cell. Biol. 15, 2791-2799
30. Foschi, M., Chari, S., Dunn, M. J., and Sorokin, A. (1997) EMBO J. 16, 6439-6451
31. Waters, S. B., Holt, K. H., Ross, S. E., Syu, L. J., Guan, K. L., Saltiel, A. R., Koretzky, G. A., and Pessin, J. E. (1995) J. Biol. Chem. 270, 20883-20886
32. Waters, S. B., Chen, D., Kao, A. W., Okada, S., Holt, K. H., and Pessin, J. E. (1996) J. Biol. Chem. 271, 18224-18230
33. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
34. Taylor, S. J., and Shalloway, D. (1996) Curr. Biol. 6, 1621-1627
35. Cherniack, A. D., Klarlund, J. K., and Czech, M. P. (1994) J. Biol. Chem. 269, 4717-4720
36. Chen, D., Waters, S. B., Holt, K. H., and Pessin, J. E. (1996) J. Biol. Chem. 271, 6328-6332
37. Zhao, H., Okada, S., Pessin, J. E., and Koretzky, G. A. (1998) J. Biol. Chem. 273, 12061-12067
38. Buday, L., and Downward, J. (1993) Cell 73, 611-620
39. Byrne, J. L., Paterson, H. F., and Marshall, C. J. (1996) Oncogene 13, 2055-2065
40. Gale, N. W., Kaplan, S., Lowenstein, E. J., Schlessinger, J., and Bar-Sagi, D. (1993) Nature 363, 88-92
41. McCormick, F. (1994) Curr. Opin. Genet. & Dev. 4, 71-76
42. Klarlund, J. K., Cherniack, A. D., and Czech, M. P. (1995) J. Biol. Chem. 270, 23421-23428
43. Kusari, A. B., Byon, J., Bandyopadhyay, D., Kenner, K. A., and Kusari, J. (1997) Mol. Endocrinol. 11, 1532-1543
44. Saltiel, A. R. (1994) FASEB J. 8, 1034-1040
45. White, M. F., and Kahn, C. R. (1994) J. Biol. Chem. 269, 1-4
46. Holt, K. H., Kasson, B. G., and Pessin, J. E. (1996) Mol. Cell. Biol. 16, 577-583
47. Rozakis-Adcock, M., van der Geer, P., Mbamalu, G., and Pawson, T. (1995) Oncogene 11, 1417-1426
48. Burgering, B. M., Pronk, G. J., van Weeren, P. C., Chardin, P., and Bos, J. L. (1993) EMBO J. 12, 4211-4220
49. Corbalan-Garcia, S., Degenhardt, K. R., and Bar-Sagi, D. (1996) Oncogene 12, 1063-1068
50. Olivier, J. P., Raabe, T., Henkemeyer, M., Dickson, B., Mbamalu, G., Margolis, B., Schlessinger, J., Hafen, E., and Pawson, T. (1993) Cell 73, 179-191
51. Rozakis-Adcock, M., Fernley, R., Wade, J., Pawson, T., and Bowtell, D. (1993) Nature 363, 83-85
52. Quilliam, L. A., Huff, S. Y., Rabun, K. M., Wei, W., Park, W., Broek, D., and Der, C. J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8512-8516
53. Chen, R. H., Corbalan-Garcia, S., and Bar-Sagi, D. (1997) EMBO J. 16, 1351-1359
54. Zhao, H., Li, Y. Y., Fucini, R. V., Ross, S. E., Pessin, J. E., and Koretzky, G. A. (1997) J. Biol. Chem. 272, 21625-21634
55. Klarlund, J. K., Cherniack, A. D., McMahon, M., and Czech, M. P. (1996) J. Biol. Chem. 271, 16674-16677
56. Combettes-Souverain, M., and Issad, T. (1998) Diabetes Metab. 24, 477-489