Electrostatic and aromatic microdomains within the binding-site crevice of the D2 receptor: Contributions of the second membrane-spanning segment

Biochemistry

Volumn 38, Issue 25, 1999, Pages 7961-7968

  Javitch, Jonathan A ^a,c   Ballesteros, Juan A ^b   Chen, Jiayun ^a   Chiappa, Victor ^a   Simpson, Merrill M ^a  

^a The New York Presbyterian Hospital   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c Box 7 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; DOPAMINE 2 RECEPTOR; SULPIRIDE;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; HYDROPHILICITY; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; ASPARTIC ACID; BINDING, COMPETITIVE; CELL LINE; CELL MEMBRANE; CYSTEINE; DOPAMINE ANTAGONISTS; ELECTROSTATICS; ETHYL METHANESULFONATE; HUMANS; MESYLATES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, DOPAMINE D2; SULPIRIDE;

EID: 0033594927     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9905314     Document Type: Article

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