Differentiation of T-helper lymphocytes: Selective regulation by members of the STAT family of transcription factors

Genes to Cells

Volumn 1, Issue 6, 1996, Pages 507-515

  Schindler, Ulrike ^a   Hoey, Timothy ^a   McKnight, Steven L ^a,b  

^a AMGEN INC   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 4; PHOSPHOTYROSINE; TRANSCRIPTION FACTOR;

ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HELPER CELL; HUMAN; IMMUNOLOGY; METABOLISM; REVIEW; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ANIMALS; CELL DIFFERENTIATION; CYTOKINES; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-12; INTERLEUKIN-4; PHOSPHOTYROSINE; RECEPTORS, CYTOKINE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 0030155938     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1996.d01-263.x     Document Type: Article

References (8)

1. Akira, S., Nishio, Y., Inoue, M., et al. (1994) Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 77, 63-71.
2. Bacon, C.M., Petricoin III, E.F., Ortaldo, J.R., et al. (1995) Interleukin 12 induces tyrosine phosphorylation, and activation of STAT4 in human lymphocytes. Prof. Natl. Acad. Sci. USA 92, 7307-7311.
3. Chua, A.O., Chizzonite, R., Desai, B.B., et al. (1994) Expression cloning of a human IL-12 receptor component. J. Immunol. 153, 128-136.
4. Gaffen, S.L., Lai, S.Y., Xu, W., et al. (1995) Signaling through the interleukin 2 receptor beta chain activates a STAT5-like DNA binding activity. Prof. Natl Acad. Sci. USA 92, 7192-7196.
5. Gearing, D.P., Comeau, M.R., et al (1992) The IL-6 signal transducer, gp130: and oncostatin M receptor and affinity converter for the LIF receptor. Science 255, 1434-1437.
6. Weinberg, A.D. & English., M. (1990) T cell subsets: lymphkine secretion of memory cells and of effector cells that develop from precursors. J. Immnnol. 144, 1788-1799.
7. Yan, H., Greenlund, A.C., Gupta, S., et al. (1996) Phosphorylated interferon-α receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113kDa STAT2 protein. EMBO J. 15, 1064-1074.
8. Zhong, Z., Wen, Z. & Darnell Jr., J.E. (1994) Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and Interleukin-6. Science 264, 95-98.