Practical synthesis of fully-substituted peptide thiazoles

Tetrahedron Letters

Volumn 40, Issue 21, 1999, Pages 3985-3988

  Buchanan, John L ^a   Mani, Ukti N ^a   Plake, Hilary R ^a   Holt, Dennis A ^a  

^a Ariad Pharmaceutical   (United States)

Author keywords

Amido ketones; Amino acids and derivatives; Grignard reactions reagents; Thiazoles

Indexed keywords

AMINO ACID; FUNCTIONAL GROUP; ORGANOMETALLIC COMPOUND; PEPTIDE THIAZOLE DERIVATIVE; REAGENT; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0033591146     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00659-0     Document Type: Article

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35. 35 All compounds were purified to homogeneity and exhibited satisfactory analytical and spectroscopic properties.
36. +, 467.2368; found, 467.2347.
37. +, 489.2212; found, 489.2198.