Design, synthesis, activity, and structure of a novel class of matrix metalloproteinase inhibitors containing a heterocyclic P'2-P'3 amide bond isostere

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 13, 1996, Pages 1601-1606

  Chen, Jian Jeffrey ^a   Zhang, Yiping ^a   Hammond, Scott ^a   Dewdney, Nolan ^a   Ho, Teresa ^a   Lin, Xiaohong ^a   Browner, Michelle F ^a   Castelhano, Arlindo L ^a,b  

^a ROCHE BIOSCIENCE   (United States)

^b Cadus Pharmaceutical Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; COLLAGENASE INHIBITOR; IMIDAZOLE DERIVATIVE; MATRILYSIN; RS 39066; UNCLASSIFIED DRUG;

ARTICLE; COLLAGEN SYNTHESIS; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; INHIBITION KINETICS; STRUCTURE ACTIVITY RELATION;

EID: 0030576302     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00283-1     Document Type: Article

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