Muscle-specific expression of hepatitis B surface antigen: No effect on DNA-raised immune responses

Virology

Volumn 260, Issue 1, 1999, Pages 74-83

  Loirat, Delphine ^a   Li, Zhenlin ^a   Mancini, Maryline ^a   Tiollais, Pierre ^a   Paulin, Denise ^a   Michel, Marie Louise ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B SURFACE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; HEPATITIS B VIRUS; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY;

EID: 0033587648     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.9795     Document Type: Article

References (47)

1. Akbari O., Panjwani N., Garcia S., Tascone R., Lowrie D., Stockinger B. DNA vaccination: Transfection and activation of dendritic cells as key events for immunity. J. Exp. Med. 189:1999;169-177.
2. Ando K., Guidotti L. G., Wirth S., Ishikawa T., Missale G., Moriyama T., Schreiber R. D., Schlicht H. J., Huang S., Chisari F. V. Class I-restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo. J. Immunol. 152:1994;3245-3253.
3. Boyer J. D., Ugen K. E., Wang B., Agadjanyan M. G., Gilbert L., Bagarazzi M. L., Chattergoon M., Frost P., Javadian A., Williams W. V., Refaeli Y., Ciccareli R. B., McCallus D., Coney L., Weiner D. B. Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination. Nat. Med. 3:1997;526-532.
4. Boyle J. S., Brady J. L., Lew A. M. Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction. Nature. 392:1998;408-411.
5. + cells. Virology. 225:1996;248-253.
6. Casares S., Inaba K., Brumeanu T.-D., Steinman R. M., Bona C. A. Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope. J. Exp. Med. 186:1997;1481-1486.
7. Chattergoon M. A., Robinson T. M., Boyer J. D., Weiner D. B. Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells. J. Immunol. 160:1998;5707-5718.
8. Chisari F. V. Hepatitis B virus immunopathogenesis. Annu. Rev. Immunol. 13:1995;29-60.
9. Chow Y.-H., Huang W.-L., Chi W.-K., Chu Y.-D., Tao M.-H. Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2. J. Virol. 71:1997;169-178.
10. Chu R. S., Targoni O. S., Krieg A. M., Lehmann P. V., Harding C. V. CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J. Exp. Med. 186:1997;1623-1631.
11. Condon C., Watkins S. C., Celluzzi C. M., Thompson K., Falo L. D. Jr. DNA-based immunization by in vivo transfection of dendritic cells. Nat. Med. 2:1996;1122-1128.
12. Davis H. L., Michel M.-L., Whalen R. G. DNA based immunization for hepatitis B induces continuous secretion of antigen and high levels of circulating antibody. Hum. Mol. Genet. 2:1993a;1847-1851.
13. Davis H. L., Millan C. L., Watkins S. C. Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA. Gene Ther. 4:1997;181-188.
14. Davis H. L., Schirmbeck R., Reimann J., Whalen R. G. DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein. Hum. Gene Ther. 6:1995;1447-1456.
15. Davis H. L., Whalen R. G., Demeneix B. A. Direct gene transfer into skeletal muscle in vivo: Factors affecting efficiency of transfer and stability of expression. Hum. Gene Ther. 4:1993b;151-159.
16. Donnelly J. J., Ulmer J. B., Shiver J. W., Liu M. A. DNA vaccines. Annu. Rev. Immunol. 15:1997;617-648.
17. Fu T. M., Ulmer J. B., Caulfield M. J., Deck R. R., Friedman A., Wang S., Liu X., Donnelly J. J., Liu M. A. Priming of cytotoxic T lymphocytes by DNA vaccines: Requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes. Mol. Med. 3:1997;362-371.
18. Haddad D., Liljeqvist S., Stahl S., Andersson I., Perlmann P., Berzins K., Ahlborg N. Comparative study of DNA-based immunization vectors: Effect of secretion signals on the antibody responses in mice. FEMS Immunol. Med. Microbiol. 18:1997;193-202.
19. Hohlfeld R., Engel A. G. The immunobiology of muscle. Immunol. Today. 15:1994;269-273.
20. Iwasaki A., Torres C. T., Ohashi P. S., Robinson H. L., Barber B. H. The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites. J. Immunol. 159:1997;11-14.
21. Langermann S. Site-directed immunogenesis. Nat. Med. 4:1998;547-548.
22. Le Borgne S., Mancini M., Le Grand R., Schleef M., Dormont D., Tiollais P., Rivière Y., Michel M.-L. In vivo induction of specific cytotoxic T lymphocytes in mice and rhesus macaques immunized with DNA vector encoding an HIV epitope fused with hepatitis B surface antigen. Virology. 240:1998;304-315.
23. Leclerc C., Deriaud E., Rojas M., Whalen R. G. The preferential induction of a Th1 response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA. Cell Immunol. 179:1997;97-106.
24. Letvin N. L., Montefiori D. C., Yasutomi Y., Perry H. C., Davies M.-E., Lekutis C., Alroy M., Freed D. C., Lord C. I., Handt L. K., Liu M. A., Shiver J. W. Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination. Proc. Natl. Acad. Sci. USA. 94:1997;9378-9383.
25. Levy M. Y., Barron L. G., Meyer K. B., Szoka F. C. Characterization of plasmid DNA transfer into mouse skeletal muscle: Evaluation of uptake mechanism, expression and secretion of gene products into blood. Gene Ther. 3:1996;201-211.
26. Li Z., Marchand P., Humbert J., Babinet C., Paulin D. Desmin sequence elements regulating skeletal muscle-specific expression in transgenic mice. Development. 117:1993;947-959.
27. Li Z., Paulin D. High level desmin expression depends of a muscle-specific enhancer. J. Biol. Chem. 266:1991;6562-6570.
28. Li Z., Paulin D. Different factors interacts with myoblast-specific and myotube-specific enhancer regions of the human desmin gene. J. Biol. Chem. 268:1993;10403-10415.
29. MacGregor R. R., Boyer J. D., Ugen K. E., Lacy K. E., Gluckman S. J., Bagarazzi M. L., Chattergoon M. A., Baine Y., Higgins T. J., Ciccarelli R. B., Coney L. R., Ginsberg R. S., Weiner D. B. First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: Safety and host response. J. Infect. Dis. 178:1998;92-100.
30. Major M. E., Vitvitski L., Mink M. A., Schleef M., Whalen R. G., Trepo C., Inchauspe G. DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid. J. Virol. 69:1995;5798-5805.
31. Mancini M., Davis H. L., Tiollais P., Michel M.-L. DNA-based immunization against the envelope proteins of the hepatitis B virus. J. BioTechniques. 44:1996;47-57.
32. Mancini M., Hadchouel M., Tiollais P., Pourcel C., Michel M.-L. Induction of anti-hepatitis B surface antigen (HBsAg) antibodies in HBsAg transgenic mice: A possible way of circumventing "nonresponse" to HBsAg. J. Med. Virol. 39:1993;67-74.
33. Mehta A., Lu X., Block T. M., Blumberg B. S., Dwek R. A. Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: Evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion. Proc. Natl. Acad. Sci. USA. 94:1997;1822-1827.
34. Michel M.-L., Davis H. L., Schleef M., Mancini M., Tiollais P., Whalen R. G. DNA-mediated immunization to the hepatitis B surface antigen in mice: Aspects of the humoral response mimic hepatitis B viral infection in humans. Proc. Natl. Acad. Sci. USA. 92:1995;5307-5311.
35. Naffakh N., Pinset C., Montarras D., Li Z., Paulin D., Danos O., Heard J.-M. Long-term secretion of therapeutic proteins from genetically modified skeletal muscles. Hum. Gene Ther. 7:1996;11-21.
36. Pimorady-Esfahani A., Grounds M. D., McMenamin P. G. Macrophages and dendritic cells in normal and regenerating murine skeletal muscle. Muscle Nerve. 20:1997;158-166.
37. Robinson H. L., Torres C. DNA vaccines. Semin. Immunol. 9:1997;271-283.
38. Sasaki S., Hamajima K., Fukushima J., Ihata A., Hishii N., Gorai I., Hirahara F., Mohri H., Okuda K. Comparison of intranasal and intramuscular immunization against human immunodeficiency virus type I with a DNA-monophosphoryl lipid A adjuvant vaccine. Infect. Immun. 66:1998;823-830.
39. Sato Y., Roman M., Tighe H., Lee D., Corr M., Nguyen M. D., Silverman G. J., Lotz M., Carson D. A., Raz E. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science. 273:1996;352-354.
40. Schirmbeck R., Melber K., Kuhröber A., Janowicz Z. A., Reimann J. Immunization with soluble hepatitis B virus surface protein elicits murine H-2 class I-restricted CD8+ cytotoxic T lymphocyte responses in vivo. J. Immunol. 152:1994;1110-1119.
41. Tighe H., Corr M., Roman M., Raz E. Gene vaccination: Plasmid DNA is more than just a blueprint. Immunol. Today. 19:1998;89-97.
42. Timares L., Takashima A., Johnston S. A. Quantitative analysis of the immunopotency of genetically transfected dendritic cells. Proc. Natl. Acad. Sci. USA. 95:1998;13147-13152.
43. Torres C.-A. T., Iwasaki A., Barber B., Robinson H. L. Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations. J. Immunol. 158:1997;4529-4532.
44. Ulmer J. B., Deck R. R., Dewitt C. M., Donnelly J. J., Liu M. A. Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: Antigen presentation by non-muscle cells. Immunology. 89:1996;59-67.
45. Vitadello M., Schiaffino M. V., Picard A., Scarpa M., Schiaffino S. Gene transfer in regenerating muscle. Hum. Gene Ther. 5:1994;11-18.
46. Werr M., Prange R. Role for calnexin and N-linked glycosylation in the assembly and secretion of hepatitis B virus middle envelope protein particles. J. Virol. 72:1998;778-782.
47. Wolff J. A., Malone R. W., Williams P., Chong W., Ascadi G., Jani A., Felgner P. L. Direct gene transfer into mouse muscle in vivo. Science. 247:1990;1465-1468.