Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA

Gene Therapy

Volumn 4, Issue 3, 1997, Pages 181-188

  Davis, H L ^a,b   Brazolot Millan, C L ^a   Watkins, S C ^c  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Cytolytic destruction; DNA vaccine; Gene transfer; Immune response; Muscle; Reporter genes

Indexed keywords

BETA GALACTOSIDASE; DNA VACCINE; HEPATITIS B SURFACE ANTIGEN; LUCIFERASE; PLASMID DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FEMALE; GENE TRANSFER; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; MALE; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; SCID MOUSE;

EID: 0030965404     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300380     Document Type: Article

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