Solution structure and orientation of the transmembrane anchor domain of the HIV-1-encoded virus protein U by high-resolution and solid-state NMR spectroscopy

Biochemistry

Volumn 38, Issue 16, 1999, Pages 5272-5282

  Wray, Victor ^a   Kinder, Rudolf ^b   Federau, Torsten ^a   Henklein, Peter ^c   Bechinger, Burkhard ^b   Schubert, Ulrich ^d,e  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN U; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS 1; LIPID BILAYER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; CIRCULAR DICHROISM; GENE PRODUCTS, VPU; HIV-1; ION CHANNELS; LIPID BILAYERS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; PROTONS; SOLUTIONS;

EID: 0033586794     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982755c     Document Type: Article

References (71)

1. Cohen, E. A., Terwilliger, E. F., Sodroski, J. G., and Haseltine, W. A. (1988) Nature 334, 532-534.
2. Strebel, K., Klimkait, T., and Martin, M. A. (1988) Science 241, 1221-1223.
3. Huet, T., Cheynier, R., Meyerhans, A., Roelants, G., and Wain-Hobson, S. (1990) Nature 345, 356-358.
4. Strebel, K., Klimkait, T., Maldarelli, F., and Martin, M. A. (1989) J. Virol. 63, 3784-3791.
5. Klimkait, T., Strebel, K., Hoggan, M. D., Martin, M. A., and Orenstein, J. M. (1990) J. Virol. 64, 621-629.
6. Maldarelli, F., Chen, M.-Y., Willey, R. L., and Strebel, K. (1993) J. Virol. 67, 5056-5061.
7. Chen, M.-Y., Maldarelli, F., Karczewski, M. K., Willey, R. L., and Strebel, K. (1993) J. Virol. 67, 3877-3884.
8. Schubert, U., Schneider, T., Henklein, P., Hoffmann, K., Berthold, E., Hauser, H., Pauli, G., and Porstmann, T. (1992) Eur. J. Biochem. 204, 875-883.
9. Schubert, U., Henklein, P., Boldyreff, B., Wingender, E., Strebel, K., and Porstmann, T. (1994) J. Mol. Biol. 236, 16-25.
10. Schubert, U., Ferrer-Montiel, A. F., Oblatt-Montal, M., Henklein, P., Strebel, K., and Montal, M. (1996) FEBS Lett. 398, 12-18.
11. Ewart, G. D., Sutherland, T., Gage, P. W., and Cox, G. B. (1996) J. Virol. 70, 7108-7115.
12. Terwilliger, E. F., Cohen, E. A., Lu, Y., Sodroski, J. G., and Haseltine, W. A. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 5163-5167.
13. Schubert, U., Bour, S., Ferrer-Montiel, A. F., Montal, M., Maldarelli, F., and Strebel, K. (1996) J. Virol. 70, 809-819.
14. Willey, R. L., Maldarelli, F., Martin, M. A., and Strebel, K. (1992) J. Virol. 66, 226-234.
15. Kerkau, T., Bacik, I., Bennink, J. R., Yewdell, J. W., Hünig, T., Schimpl, A., and Schubert, U. (1997) J. Exp. Med. 185, 1295-1305.
16. Bour, S., Schubert, U., and Strebel, K. (1995) J. Virol. 69, 1510-1520.
17. Schubert, U., and Strebel, K. (1994) J. Virol. 68, 2260-2271.
18. Paul, M., and Jabbar, M. A. (1997) Virology 232, 207-216.
19. Friborg, J., Ladha, A., Goettlinger, H., Haseltine, W. A., and Cohen, E. A. (1995) J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 8, 10-22.
20. Margottin, F., Bour, S. P., Durand, H., Selig, L., Benichou, S., Richard, V., Thomas, D., Strebel, K., and Benarous, R. (1998) Mol. Cell 1, 565-574.
21. Fujita, K., Omura, S., and Silver, J. (1997) J. Gen. Virol. 78, 619-625.
22. Schubert, U., Anton, L. C., Bacik, I., Cox, J. H., Bour, S., Bennink, J. R., Orlowski, M., Strebel, K., and Yewdell, J. W. (1998) J. Virol. 72, 2280-2288.
23. Lamb, R. A., and Pinto, L. H. (1997) Virology 229, 1-11.
24. Grice, A. L., Kerr, I. D., and Sansom, M. S. P. (1997) FEBS Lett. 405, 299-304.
25. Moore, P. B., Zhong, Q., Husslein, T., and Klein, M. L. (1998) FEBS Lett. 431, 143-148.
26. Henklein, P., Schubert, U., Kunert, O., Klabunde, S., Wray, V., Klöppel, K.-D., Kiess, M., Porstmann, T., and Schomburg, D. (1993) Pept. Res. 6, 79-87.
27. Federau, T., Schubert, U., Flossdorf, J., Henklein, P., Schomburg, D., and Wray, V. (1996) Int. J. Pept. Protein Res. 47, 297-310.
28. Wray, V., Federau, T., Henklein, P., Klabunde, S., Kunert, O., Schomburg, D., and Schubert, U. (1995) Int. J. Pept. Protein Res. 45, 35-43.
29. Willbold, D., Hoffmann, S., and Rösch, P. (1997) Eur. J. Biochem. 245, 581-588.
30. Cross, T. A., and Opella, S. J. (1994) Curr. Opin. Struct. Biol. 4, 574-581.
31. Bechinger, B., Kim, Y., Chirlian, L. E., Gesell, J., Neumann, J.-M., Montal, M., Tomich, J., Zasloff, M., and Opella, S. J. (1991) J. Biomol. NMR 1, 167-173.
32. Myers, G., Foley, B., Mellors, J. W., Korber, B., Jeang, K. T., and Wain-Hobson, S. (1996) Human retroviruses and AIDS, Los Alamos National Laboratory, Los Alamos, NM.
33. Adachi, A., Gendelman, H. E., Koenig, S., Folks, T., Willey, R. L., Rabson, A., and Martin, M. A. (1986) J. Virol. 59, 284-291.
34. Bechinger, B., and Opella, S. J. (1991) J. Magn. Reson. 95, 585-588.
35. Pines, A., Gibby, M. G., and Waugh, J. S. (1973) J. Chem. Phys. 59, 569-590.
36. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, Wiley-Interscience, New York.
37. Niedig, K. P., and Kalbitzer, H. R. (1990) J. Magn. Reson. 88, 155-160.
38. Gronwald, W., Schomburg, D., Harder, M. P. F., Mayer, H., Paulsen, J., Wingender, E., and Wray, V. (1996) Biol. Chem. Hoppe-Seyler 377, 175-186.
39. Brünger, A. T. (1992) X-PLOR, Version 3.1, A System for X-ray Crystallography and NMR, Yale University Press, New Haven, CT.
40. Schomburg, D., and Reichelt, J. (1988) J. Mol. Graphics 6, 161-165.
41. Blankenfeldt, W., Nokihara, K., Naruse, S., Lessel, U., Schomburg, D., and Wray, V. (1996) Biochemistry 35, 5955-5962.
42. Greenfield, N., and Fasman, G. D. (1969) Biochemistry 8, 4108-4116.
43. Wray, V., Mertins, D., Kiess, M., Henklein, P., Trowitzsch-Kienast, W., and Schubert, U. (1998) Biochemistry 37, 8527-8538.
44. Wishart, D. S., Sykes, B. D., and Richards, F. M. (1992) Biochemistry 31, 1647-1651.
45. Scherer, P. G., and Seelig, G. (1989) Biochemistry 28, 7720-7727.
46. Smith, R., Separovic, F., Milne, T. J., Whittaker, A., Bennett, F. M., Cornell, B. A., and Makriyannis, A. (1994) J. Mol. Biol. 241, 456-466.
47. North, C. L., Barranger-Mathys, M., and Cafiso, D. S. (1995) Biophys. J. 69, 2392-2397.
48. Bechinger, B. (1996) J. Mol. Biol. 263, 768-775.
49. Bechinger, B., Zasloff, M., and Opella, S. J. (1993) Protein Sci. 2, 2077-2084.
50. Ketchem, R. K., Hu, W., and Cross, T. A. (1993) Science 261, 1457-1460.
51. Oas, T. G., Hartzell, C. J., Dahlquist, F. W., and Drobny, G. P. (1987) J. Am. Chem. Soc. 109, 5962-5966.
52. Hartzell, C. J., Whitfield, M., Oas, T. G., and Drobny, G. P. (1987) J. Am. Chem. Soc. 109, 5966-5969.
53. Wu, C. H., Ramamoorthy, A., Gierasch, L. M., and Opella, S. J. (1995) J. Am. Chem. Soc. 117, 6148-6149.
54. Bechinger, B., Gierasch, L. M., Montal, M., Zasloff, M., and Opella, S. J. (1996) Solid State Nucl. Magn. Reson. 7, 185-192.
55. Kovacs, F. A., and Cross, T. A. (1997) Biophys. J. 73, 2511-2517.
56. Teng, Q., and Cross, T. A. (1989) J. Magn. Reson. 85, 439-447.
57. Shoji, A., Ozaki, T., Fujito, T., Deguchi, K., Ando, S., and Ando, I. (1989) Macromolecules 22, 2860-2863.
58. Shoji, A., Ozaki, T., Fujito, T., Deguchi, K., Ando, S., and Ando, I. (1990) J. Am. Chem. Soc. 112, 4693-4697.
59. Doak, D. G., Mulvey, D., Kawaguchi, K., Villalain, J., and Campbell, I. D. (1996) J. Mol. Biol. 258, 672-687.
60. Gargaro, A. R., Bloomberg, G. B., Dempsey, C. E., Murray, M., and Tanner, M. J. A. (1994) Eur. J. Biochem. 221, 445-454.
61. Norwood, T. J., Crawford, D. A., Steventon, M. E., Driscoll, P. C., and Campbell, I. D. (1992) Biochemistry 31, 6285-6290.
62. Girvin, M. E., Rastogi, V. K., Abildgaard, F., Markley, J. L., and Fillingame, R. H. (1998) Biochemistry 37, 8817-8824.
63. Pinto, L. H., Holsinger, J., and Lamb, R. A. (1992) Cell 69, 517-528.
64. Sugrue, R. J., and Hay, A. J. (1991) Virology 180, 617-624.
65. Wang, C., Takeuchi, K., Pinto, L. H., and Lamb, R. A. (1993) J. Virol. 67, 5585-5594.
66. Wang, S., Lamb, R. A., and Pinto, L. H. (1995) Biophys. J. 69, 1363-1371.
67. Coady, M. J., Daniel, N. G., Tiganos, E., Allain, B., Friborg, J., Lapointe, J.-Y., and Cohen, E. A. (1998) Virology 244, 39-49.
68. Holsinger, L. J., and Lamb, R. A. (1991) Virology 183, 32-43.
69. Gilbert, G. E., and Baleja, J. D. (1995) Biochemistry 34, 3022-3031.
70. Kaiser, E. T., and Kezdy, F. J. (1987) Annu. Rev. Biophys. Biophys. Chem. 16, 561-581.
71. Lazo, N. D., Hu, W., and Cross, T. A. (1995) J. Magn. Reson. 107, 43-50.