Thiazolo[4,5-d]pyrimidine thiones and -ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 8, 1999, Pages 1185-1188

  Beck, James P ^a   Curry, Matt A ^a   Chorvat, Robert J ^a   Fitzgerald, Larry W ^a   Gilligan, Paul J ^a   Zaczek, Robert ^a   Trainor, George L ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; THIAZOLO[4,5 D]PYRIMIDINE THIONE; THIAZOLO[4,5 D]PYRIMIDINE THIONONE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG STRUCTURE; DRUG SYNTHESIS; PHYSICAL CHEMISTRY; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TRANQUILIZING ACTIVITY;

CELL LINE; HUMANS; PYRIMIDINES; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; STRUCTURE-ACTIVITY RELATIONSHIP; THIONES;

EID: 0033583540     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00159-6     Document Type: Article

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