Highly potent inhibitors of the Grb2-SH2 domain

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 2, 1999, Pages 221-226

  Schoepfer, Joseph ^a   Fretz, Heinz ^a   Gay, Brigitte ^a   Furet, Pascal ^a   García Echeverría, Carlos ^a   End, Nicole ^a   Caravatti, Giorgio ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL 4 PHOSPHONOMETHYLPHENYLALANINE 1 AMINOCYCLOHEXANECARBOXYLIC ACID (3 INDOLYLPROPYL)ASPARAGINE AMIDE; ANTINEOPLASTIC AGENT; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ENZYME-LINKED IMMUNOSORBENT ASSAY; GRB2 ADAPTOR PROTEIN; INHIBITORY CONCENTRATION 50; PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS;

EID: 0033579856     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00701-X     Document Type: Article

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