Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2- SH2 domain

Journal of Medicinal Chemistry

Volumn 40, Issue 22, 1997, Pages 3551-3556

  Furet, Pascal ^a   Gay, Brigitte ^a   García Echeverría, Carlos ^a   Rahuel, Joseph ^a   Fretz, Heinz ^a   Schoepfer, Joseph ^a   Caravatti, Giorgio ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRANILIC ACID; PEPTIDE DERIVATIVE; PHOSPHOPEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; DRUG SYNTHESIS; MOLECULAR CLONING; MOLECULAR MODEL; PEPTIDE SYNTHESIS; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANILINE COMPOUNDS; BINDING SITES; GRB2 ADAPTOR PROTEIN; MODELS, MOLECULAR; PHOSPHOPEPTIDES; PROTEIN CONFORMATION; PROTEINS; RECOMBINANT PROTEINS; SRC HOMOLOGY DOMAINS;

EID: 0030725743     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9702185     Document Type: Article

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