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Volumn 163, Issue 10, 1999, Pages 5287-5297

Induction of autoimmunity in a transgenic model of B cell receptor peripheral tolerance: Changes in coreceptors and B cell receptor-induced tyrosine-phosphoproteins

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE RECEPTOR; PHOSPHOPROTEIN; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

EID: 0033571066     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (34)

References (58)
  • 2
    • 0030913776 scopus 로고    scopus 로고
    • B-cell activation versus tolerance - The central role of immunoglobulin receptor engagement and T-cell help
    • Fulcher, D. A., and A. Basten. 1997. B-cell activation versus tolerance - the central role of immunoglobulin receptor engagement and T-cell help. Int. Rev. Immunol. 15:33.
    • (1997) Int. Rev. Immunol. , vol.15 , pp. 33
    • Fulcher, D.A.1    Basten, A.2
  • 3
    • 0024455288 scopus 로고
    • Induction of self-tolerance in mature peripheral B lymphocytes
    • Goodnow, C. C., J. Crosbie, H. Jorgensen, R. A. Brink, and A. Basten. 1989. Induction of self-tolerance in mature peripheral B lymphocytes. Nature 342:385.
    • (1989) Nature , vol.342 , pp. 385
    • Goodnow, C.C.1    Crosbie, J.2    Jorgensen, H.3    Brink, R.A.4    Basten, A.5
  • 5
    • 0026762942 scopus 로고
    • Transgenic mice and analysis of B-cell tolerance
    • Goodnow, C. C. 1992. Transgenic mice and analysis of B-cell tolerance. Annu. Rev. Immunol. 10:489.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 489
    • Goodnow, C.C.1
  • 6
    • 0028127965 scopus 로고
    • Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells
    • Cooke, M. P., A. W. Heath, K. M. Shokat, Y. Zeng, F. D. Finkelman, P. S. Linsley, M. Howard, and C. C. Goodnow. 1994. Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells. J. Exp. Med. 179:425.
    • (1994) J. Exp. Med. , vol.179 , pp. 425
    • Cooke, M.P.1    Heath, A.W.2    Shokat, K.M.3    Zeng, Y.4    Finkelman, F.D.5    Linsley, P.S.6    Howard, M.7    Goodnow, C.C.8
  • 7
    • 0032541486 scopus 로고    scopus 로고
    • Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells
    • Rathmell, J. C., S. Fournier, B. C. Weintraub, J. P. Allison, and C. C. Goodnow. 1998. Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. J. Exp. Med. 188: 651.
    • (1998) J. Exp. Med. , vol.188 , pp. 651
    • Rathmell, J.C.1    Fournier, S.2    Weintraub, B.C.3    Allison, J.P.4    Goodnow, C.C.5
  • 8
    • 0032536832 scopus 로고    scopus 로고
    • Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded
    • Foote, L. C., A. Marshak-Rothstein, and T. L. Rothstein. 1998. Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded. J. Exp. Med. 187:847.
    • (1998) J. Exp. Med. , vol.187 , pp. 847
    • Foote, L.C.1    Marshak-Rothstein, A.2    Rothstein, T.L.3
  • 9
    • 0028214982 scopus 로고
    • Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signals but are defective in antigen-receptor- mediated functions
    • Eris, J. M., A. Basten, R. Brink, K. Doherty, M. R. Kehry, and P. D. Hodgkin. 1994. Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signals but are defective in antigen-receptor- mediated functions. Proc. Natl. Acad. Sci. USA 91:4392.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4392
    • Eris, J.M.1    Basten, A.2    Brink, R.3    Doherty, K.4    Kehry, M.R.5    Hodgkin, P.D.6
  • 11
    • 0026533967 scopus 로고
    • Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice
    • Mason, D. Y., M. Jones, and C. C. Goodnow. 1992. Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice. Int. Immunol. 4:163.
    • (1992) Int. Immunol. , vol.4 , pp. 163
    • Mason, D.Y.1    Jones, M.2    Goodnow, C.C.3
  • 13
    • 0029550111 scopus 로고
    • Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate
    • Cyster, J. G., and C. C. Goodnow. 1995. Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate. Immunity 3:691.
    • (1995) Immunity , vol.3 , pp. 691
    • Cyster, J.G.1    Goodnow, C.C.2
  • 14
    • 0031879766 scopus 로고    scopus 로고
    • Rescue of self-reactive B cells by provision of T cell help in vivo
    • Cook, M. C., A. Basten, and B. Fazekas de St. Groth. 1998. Rescue of self-reactive B cells by provision of T cell help in vivo. Eur. J. Immunol. 28:2549.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2549
    • Cook, M.C.1    Basten, A.2    Fazekas De St. Groth, B.3
  • 15
    • 0025812171 scopus 로고
    • Breakdown of self-tolerance in anergic B lymphocytes
    • Goodnow, C. C., R. Brink, and E. Adams. 1991. Breakdown of self-tolerance in anergic B lymphocytes. Nature 352:532.
    • (1991) Nature , vol.352 , pp. 532
    • Goodnow, C.C.1    Brink, R.2    Adams, E.3
  • 16
    • 0025014269 scopus 로고
    • Allotype-specific immunoregulation of autoantibody production by host B cells in chronic graft-versus host disease
    • Morris, S. C., R. L. Cheek, P. L. Cohen, and R. A. Eisenberg. 1990. Allotype-specific immunoregulation of autoantibody production by host B cells in chronic graft-versus host disease. J. Immunol. 144:916.
    • (1990) J. Immunol. , vol.144 , pp. 916
    • Morris, S.C.1    Cheek, R.L.2    Cohen, P.L.3    Eisenberg, R.A.4
  • 17
    • 0025093055 scopus 로고
    • Experimental induction of systemic lupus erythematosus by recognition of foreign Ia
    • Morris, S. C., P. L. Cohen, and R. A. Eisenberg. 1990. Experimental induction of systemic lupus erythematosus by recognition of foreign Ia. Clin. Immunol. Immunopathol. 57:263.
    • (1990) Clin. Immunol. Immunopathol. , vol.57 , pp. 263
    • Morris, S.C.1    Cohen, P.L.2    Eisenberg, R.A.3
  • 18
    • 0020559601 scopus 로고
    • Class II major histocompatibility antigens and the etiology of systemic lupus erythematosus
    • Eisenberg, R. A., and P. L. Cohen. 1983. Class II major histocompatibility antigens and the etiology of systemic lupus erythematosus. Clin. Immunol. Immunopathol. 29:1.
    • (1983) Clin. Immunol. Immunopathol. , vol.29 , pp. 1
    • Eisenberg, R.A.1    Cohen, P.L.2
  • 19
    • 0032403548 scopus 로고    scopus 로고
    • The role of host (endogenous) T cells in chronic graft-versus-host autoimmune disease
    • Chen, F., M. A. Maldonado, M. Madaio, and R. A. Eisenberg. 1998. The role of host (endogenous) T cells in chronic graft-versus-host autoimmune disease. J. Immunol. 161:5880.
    • (1998) J. Immunol. , vol.161 , pp. 5880
    • Chen, F.1    Maldonado, M.A.2    Madaio, M.3    Eisenberg, R.A.4
  • 20
    • 0025138736 scopus 로고
    • Autoantibodies in chronic graft versus host result from cognate T-B interactions
    • Morris, S. C., R. L. Cheek, P. L. Cohen, and R. A. Eisenberg. 1990. Autoantibodies in chronic graft versus host result from cognate T-B interactions. J. Exp. Med. 171:503.
    • (1990) J. Exp. Med. , vol.171 , pp. 503
    • Morris, S.C.1    Cheek, R.L.2    Cohen, P.L.3    Eisenberg, R.A.4
  • 21
    • 0030023652 scopus 로고    scopus 로고
    • Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45
    • Cyster, J. G., J. I. Healy, K. Kishihara, T. W. Mak, M. L. Thomas, and C. C. Goodnow. 1996. Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45. Nature 381:325.
    • (1996) Nature , vol.381 , pp. 325
    • Cyster, J.G.1    Healy, J.I.2    Kishihara, K.3    Mak, T.W.4    Thomas, M.L.5    Goodnow, C.C.6
  • 22
    • 0019159670 scopus 로고
    • Regulation of murine B cells through surface immunoglobulin. I. Monoclonal anti-delta antibody that induces allotype-specific proliferation
    • Zitron, I. M., and B. L. Clevinger. 1980. Regulation of murine B cells through surface immunoglobulin. I. Monoclonal anti-delta antibody that induces allotype-specific proliferation. J. Exp. Med. 152:1135.
    • (1980) J. Exp. Med. , vol.152 , pp. 1135
    • Zitron, I.M.1    Clevinger, B.L.2
  • 23
    • 0023655663 scopus 로고
    • "Numatrin," a nuclear matrix protein associated with induction of proliferation in B lymphocytes
    • Feuerstein, N., and J. J. Mond. 1987. "Numatrin," a nuclear matrix protein associated with induction of proliferation in B lymphocytes. J. Biol. Chem. 262: 11389.
    • (1987) J. Biol. Chem. , vol.262 , pp. 11389
    • Feuerstein, N.1    Mond, J.J.2
  • 24
    • 0023682002 scopus 로고
    • Identification of numatrin, the nuclear matrix protein associated with induction of mitogenesis, as the nucleolar protein B23: Implication for the role of the nucleolus in early transduction of mitogenic signals
    • Feuerstein, N., P. K. Chan, and J. J. Mond. 1988. Identification of numatrin, the nuclear matrix protein associated with induction of mitogenesis, as the nucleolar protein B23: implication for the role of the nucleolus in early transduction of mitogenic signals. J. Biol. Chem. 263:10608.
    • (1988) J. Biol. Chem. , vol.263 , pp. 10608
    • Feuerstein, N.1    Chan, P.K.2    Mond, J.J.3
  • 25
    • 0032489560 scopus 로고    scopus 로고
    • Association of activating transcription factor 2 (ATF2) with the ubiquitin-conjugating enzyme hUBC9: Implication of the ubiquitin/proteasome pathway in regulation of ATF2 in T cells
    • Firestein, R., and N. Feuerstein. 1998. Association of activating transcription factor 2 (ATF2) with the ubiquitin-conjugating enzyme hUBC9: implication of the ubiquitin/proteasome pathway in regulation of ATF2 in T cells. J. Biol. Chem. 273:5892.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5892
    • Firestein, R.1    Feuerstein, N.2
  • 26
    • 0028861545 scopus 로고
    • Regulation of cAMP-responsive enhancer binding proteins during cell cycle progression in T lymphocytes stimulated by IL-2
    • Feuerstein, N., D. Huang, S. H. Hinrichs, D. J. Orten, N. Aiyar, and M. B. Prystowsky. 1995. Regulation of cAMP-responsive enhancer binding proteins during cell cycle progression in T lymphocytes stimulated by IL-2. J. Immunol. 154:68.
    • (1995) J. Immunol. , vol.154 , pp. 68
    • Feuerstein, N.1    Huang, D.2    Hinrichs, S.H.3    Orten, D.J.4    Aiyar, N.5    Prystowsky, M.B.6
  • 30
    • 0022646588 scopus 로고
    • Decreased expression of the C3b/C4b receptor (CR1) and the C3d receptor (CR2) on B lymphocytes and of CR1 on neutrophils of patients with systemic lupus erythematosus
    • Wilson, J. G., W. D. Ratnoff, P. H. Schur, and D. T. Fearon. 1986. Decreased expression of the C3b/C4b receptor (CR1) and the C3d receptor (CR2) on B lymphocytes and of CR1 on neutrophils of patients with systemic lupus erythematosus. Arthritis Rheum. 29:739.
    • (1986) Arthritis Rheum. , vol.29 , pp. 739
    • Wilson, J.G.1    Ratnoff, W.D.2    Schur, P.H.3    Fearon, D.T.4
  • 31
    • 0026480851 scopus 로고
    • T lymphocyte expression of complement receptor 2 (CR2/CD21): A role in adhesive cell-cell interactions and dysregulation in a patient with systemic lupus erythematosus (SLE)
    • Levy, E., J. Ambrus, L. Kahl, H. Molina, K. Tung, and V. M. Holers. 1992. T lymphocyte expression of complement receptor 2 (CR2/CD21): a role in adhesive cell-cell interactions and dysregulation in a patient with systemic lupus erythematosus (SLE). Clin. Exp. Immunol. 90:235.
    • (1992) Clin. Exp. Immunol. , vol.90 , pp. 235
    • Levy, E.1    Ambrus, J.2    Kahl, L.3    Molina, H.4    Tung, K.5    Holers, V.M.6
  • 32
    • 0029014256 scopus 로고
    • Complement receptor expression and activation of the complement cascade on B lymphocytes from patients with systemic lupus erythematosus (SLE)
    • Marquart, H. V., A. Svendsen, J. M. Rasmussen, C. H. Nielsen, P. Junker, S. E. Svehag, and R. G. Leslie. 1995. Complement receptor expression and activation of the complement cascade on B lymphocytes from patients with systemic lupus erythematosus (SLE). Clin. Exp. Immunol. 101:60.
    • (1995) Clin. Exp. Immunol. , vol.101 , pp. 60
    • Marquart, H.V.1    Svendsen, A.2    Rasmussen, J.M.3    Nielsen, C.H.4    Junker, P.5    Svehag, S.E.6    Leslie, R.G.7
  • 33
    • 0028783396 scopus 로고
    • Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling
    • Kurosaki, T., S. A. Johnson, L. Pao, K. Sada, H. Yamamura, and J. C. Cambier. 1995. Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling. J. Exp. Med. 182:1815.
    • (1995) J. Exp. Med. , vol.182 , pp. 1815
    • Kurosaki, T.1    Johnson, S.A.2    Pao, L.3    Sada, K.4    Yamamura, H.5    Cambier, J.C.6
  • 34
    • 0030831199 scopus 로고    scopus 로고
    • The complexity of signaling pathways activated by the BCR
    • DeFranco, A. L. 1997. The complexity of signaling pathways activated by the BCR. Curr. Opin. Immunol. 9:296.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 296
    • DeFranco, A.L.1
  • 35
    • 0031882091 scopus 로고    scopus 로고
    • A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice
    • Chan, O., and M. J. Shlomchik. 1998. A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice. J. Immunol. 160:51.
    • (1998) J. Immunol. , vol.160 , pp. 51
    • Chan, O.1    Shlomchik, M.J.2
  • 37
    • 0027447188 scopus 로고
    • Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
    • Hartley, S. B., M. P. Cooke, D. A. Fulcher, A. W. Harris, S. Cory, A. Basten, and C. C. Goodnow. 1993. Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell 72:325.
    • (1993) Cell , vol.72 , pp. 325
    • Hartley, S.B.1    Cooke, M.P.2    Fulcher, D.A.3    Harris, A.W.4    Cory, S.5    Basten, A.6    Goodnow, C.C.7
  • 41
    • 0030852770 scopus 로고    scopus 로고
    • Induction of B cell apoptosis by co-cross-linking CD23 and sIg involves aberrant regulation of c-myc and is inhibited by bcl-2
    • Campbell, K. A., E. J. Studer, M. A. Kilmon, A. Lees, F. Finkelman, and D. H. Conrad. 1997. Induction of B cell apoptosis by co-cross-linking CD23 and sIg involves aberrant regulation of c-myc and is inhibited by bcl-2. Int. Immunol. 9:1131.
    • (1997) Int. Immunol. , vol.9 , pp. 1131
    • Campbell, K.A.1    Studer, E.J.2    Kilmon, M.A.3    Lees, A.4    Finkelman, F.5    Conrad, D.H.6
  • 43
    • 0030985193 scopus 로고    scopus 로고
    • Inhibition of apoptosis in a human pre-B-cell line by CD23 is mediated via a novel receptor
    • White, L. J., B. W. Ozanne, P. Graber, J. P. Aubry, J. Y. Bonnefoy, and W. Cushley. 1997. Inhibition of apoptosis in a human pre-B-cell line by CD23 is mediated via a novel receptor. Blood 90:234.
    • (1997) Blood , vol.90 , pp. 234
    • White, L.J.1    Ozanne, B.W.2    Graber, P.3    Aubry, J.P.4    Bonnefoy, J.Y.5    Cushley, W.6
  • 44
    • 0028005451 scopus 로고
    • Expression of CD5 and CD23 on B cells of patients with rheumatoid arthritis, systemic lupus erythematosus and Sjogren's syndrome: Relationship with disease activity and treatment
    • Ebo, D., L. S. DeClerck, C. H. Bridts, and W. J. Stevens. 1994. Expression of CD5 and CD23 on B cells of patients with rheumatoid arthritis, systemic lupus erythematosus and Sjogren's syndrome: relationship with disease activity and treatment. In Vivo 8:577.
    • (1994) In Vivo , vol.8 , pp. 577
    • Ebo, D.1    DeClerck, L.S.2    Bridts, C.H.3    Stevens, W.J.4
  • 45
    • 0026699357 scopus 로고
    • Soluble CD23 levels are elevated in the serum of patients with primary Sjogren's syndrome and systemic lupus erythematosus
    • Bansal, A., T. Roberts, E. M. Hay, R. Kay, R. S. Pumphrey, and P. B. Wilson. 1992. Soluble CD23 levels are elevated in the serum of patients with primary Sjogren's syndrome and systemic lupus erythematosus. Clin. Exp. Immunol. 89: 452.
    • (1992) Clin. Exp. Immunol. , vol.89 , pp. 452
    • Bansal, A.1    Roberts, T.2    Hay, E.M.3    Kay, R.4    Pumphrey, R.S.5    Wilson, P.B.6
  • 46
    • 0023356196 scopus 로고
    • The activation antigen BLAST-2, when shed, is an autocrine BCGF for normal and transformed B cells
    • Swendeman, S., and D. A. Thorley-Lawson. 1987. The activation antigen BLAST-2, when shed, is an autocrine BCGF for normal and transformed B cells. EMBO J. 6:1637.
    • (1987) EMBO J. , vol.6 , pp. 1637
    • Swendeman, S.1    Thorley-Lawson, D.A.2
  • 48
    • 0025758477 scopus 로고
    • Recombinant 25-kDa CD23 and interleukin 1α promote the survival of germinal center B cells: Evidence for bifurcation in the development of centrocytes rescued from apoptosis
    • Liu, Y. J., J. A. Cairns, M. J. Holder, S. D. Abbot, K. U. Jansen, J. Y. Bonnefoy, J. Gordon, and I. C. MacLennan. 1991. Recombinant 25-kDa CD23 and interleukin 1α promote the survival of germinal center B cells: evidence for bifurcation in the development of centrocytes rescued from apoptosis. Eur. J. Immunol. 21:1107.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1107
    • Liu, Y.J.1    Cairns, J.A.2    Holder, M.J.3    Abbot, S.D.4    Jansen, K.U.5    Bonnefoy, J.Y.6    Gordon, J.7    MacLennan, I.C.8
  • 49
    • 0031202759 scopus 로고    scopus 로고
    • Mouse complement receptors type 1 (CR1; CD35) and type 2 (CR2;CD21): Expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice
    • Takahashi, K., Y. Kozono, T. J. Waldschmidt, D. Berthiaume, R. J. Quigg, A. Baron, and V. M. Holers. 1997. Mouse complement receptors type 1 (CR1; CD35) and type 2 (CR2;CD21): expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice. J. Immunol. 159:1557.
    • (1997) J. Immunol. , vol.159 , pp. 1557
    • Takahashi, K.1    Kozono, Y.2    Waldschmidt, T.J.3    Berthiaume, D.4    Quigg, R.J.5    Baron, A.6    Holers, V.M.7
  • 50
    • 0031688491 scopus 로고    scopus 로고
    • Complement receptor 2 in the regulation of the immune response
    • Tolnay, M., and G. C. Tsokos. 1998. Complement receptor 2 in the regulation of the immune response. Clin. Immunol. Immunopathol. 88:123.
    • (1998) Clin. Immunol. Immunopathol. , vol.88 , pp. 123
    • Tolnay, M.1    Tsokos, G.C.2
  • 51
    • 0031921084 scopus 로고    scopus 로고
    • The role of complement and complement receptors in induction and regulation of immunity
    • Carroll, M. C. 1998. The role of complement and complement receptors in induction and regulation of immunity. Annu. Rev. Immunol. 16:545.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 545
    • Carroll, M.C.1
  • 53
    • 0029829026 scopus 로고    scopus 로고
    • B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events
    • Liossis, S. N., B. Kovacs, G. Dennis, G. M. Kammer, and G. C. Tsokos. 1996. B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events. J. Clin. Invest. 98:2549.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2549
    • Liossis, S.N.1    Kovacs, B.2    Dennis, G.3    Kammer, G.M.4    Tsokos, G.C.5
  • 54
    • 0028346563 scopus 로고
    • Signal transduction by the B cell antigen receptor and its coreceptors
    • Cambier, J. C., C. M. Pleiman, and M. R. Clark. 1994. Signal transduction by the B cell antigen receptor and its coreceptors. Annu. Rev. Immunol. 12:457.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 457
    • Cambier, J.C.1    Pleiman, C.M.2    Clark, M.R.3
  • 55
    • 0032541653 scopus 로고    scopus 로고
    • Antigen receptor signaling: Integration of protein lyrosine kinase functions
    • Tamir, I., and J. C. Cambier. 1998. Antigen receptor signaling: integration of protein lyrosine kinase functions. Oncogene 17:1353.
    • (1998) Oncogene , vol.17 , pp. 1353
    • Tamir, I.1    Cambier, J.C.2
  • 56
    • 0031909355 scopus 로고    scopus 로고
    • Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes
    • Jacinto, E., G. Werlen, and M. Karin. 1998. Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes. Immunity 8:31.
    • (1998) Immunity , vol.8 , pp. 31
    • Jacinto, E.1    Werlen, G.2    Karin, M.3
  • 57
    • 0028783322 scopus 로고
    • Syk tyrosine kinase required for mouse viability and B-cell development
    • Cheng, A. M., B. Rowley, W. Pao, A. Hayday, J. B. Bolen, and T. Pawson. 1995. Syk tyrosine kinase required for mouse viability and B-cell development. Nature 378:303.
    • (1995) Nature , vol.378 , pp. 303
    • Cheng, A.M.1    Rowley, B.2    Pao, W.3    Hayday, A.4    Bolen, J.B.5    Pawson, T.6


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