The novel human HUEL (C4orf1) gene maps to chromosome 4p12-p13 and encodes a nuclear protein containing the nuclear receptor interaction motif

Genomics

Volumn 59, Issue 2, 1999, Pages 224-233

  Sim, Del L C ^a   Chow, Vincent T K ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CELL NUCLEUS RECEPTOR; NUCLEAR PROTEIN;

ANTIBODY PRODUCTION; ARTICLE; CANCER CELL CULTURE; CELLULAR DISTRIBUTION; CHROMOSOMAL LOCALIZATION; CHROMOSOME 4P; CONTROLLED STUDY; DNA SEQUENCE; EXON; GENE AMPLIFICATION; GENE MAPPING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS;

EID: 0033566096     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1999.5856     Document Type: Article

References (56)

1. Adams M. D., Kelley J. M., Gocayne J. D., Dubnick M., Polymeropoulos M. H., Xiao H., Merril C. R., Wu A., Olde B., Moreno R. F., Kerlavage A. R., McCombie W. R., Venter J. C. Complementary DNA sequencing: Expressed sequence tags and human genome project. Science. 252:1991;1651-1656.
2. Akashi M., Shaw G., Hachiya M., Elstner E., Suzuki G., Koeffler P. Number and location of AUUUA motifs: Role in regulating transiently expressed RNAs. Blood. 83:1994;3182-3187.
3. Allende J. E., Allende C. C. Protein kinase CK2: An enzyme with multiple substrates and a puzzling regulation. FASEB J. 9:1995;313-323.
4. Altschul S. F., Gish W., Miller W., Myers E. W., Lipman D. J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
5. Antequera F., Bird A. Number of CpG islands and genes in human and mouse. Proc. Natl. Acad. Sci. USA. 90:1993;11995-11999.
6. Anzick S. L., Kononen J., Walker R. L., Azorsa D. O., Tanner M. M., Guan X. Y., Sauter G., Kallioniemi O. P., Trent J. M., Meltzer P. S. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science. 277:1997;965-968.
7. Berg J. M. DNA binding specificity of steroid receptors. Cell. 57:1989;1065-1068.
8. Busch S. J., Sassone-Corsi P. Dimers, leucine zippers and DNA-binding domains. Trends Genet. 6:1990;36-40.
9. Chow V. T. K., Lee S. S. DENN, a novel human gene differentially expressed in normal and neoplastic cells. DNA Sequence. 6:1996;263-273.
10. Chow V. T. K., Quek H. H. HEP-COP, a novel human gene whose product is highly homologous to the α-subunit of the yeast coatomer protein complex. Gene. 169:1996;223-227.
11. Chow V. T. K., Lim K. M., Lim D. The human DENN gene: Genomic organization, alternative splicing, and localization to chromosome 11p11.21-p11.22. Genome. 41:1998;543-552.
12. Chow V. T. K., Lim S. S., Tock E. P. C. The c-erbAβ thyroid hormone receptor: Expression and cDNA sequence analysis of the hormone-binding domain in human cancer cell lines. Acta Oncol. 33:1994;499-505.
13. Dingwall C., Laskey R. A. Nuclear targeting sequences - A consensus. Trends Biochem. Sci. 16:1991;478-481.
14. Elder P. A., Bell S. M., Knowles M. A. Deletion of two regions on chromosome 4 in bladder carcinoma: Definition of a critical 750kB region at 4p16.3. Oncogene. 9:1994;3433-3436.
15. Fukuda M., Asano S., Nakamura T., Adachi M., Yoshida M., Yanagida M., Nishida E. CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature. 390:1997;308-311.
16. Garcia-Bustos J., Heitman J., Hall M. N. Nuclear protein localization. Biochim. Biophys. Acta. 1071:1991;83-101.
17. Gerace L. Nuclear export signals and the fast track to the cytoplasm. Cell. 82:1995;341-344.
18. Glass C. K., Rose D. W., Rosenfeld M. G. Nuclear receptor coactivators. Curr. Opin. Cell Biol. 9:1997;222-232.
19. Glomset J. A., Gelb M. H., Farnsworth C. C. Prenyl proteins in eukaryotic cells: A new type of membrane anchor. Trends Biochem. Sci. 15:1990;139-142.
20. Gough N. M. Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells. Anal. Biochem. 173:1988;93-95.
21. Harlow E., Lane D. Antibodies: A Laboratory Manual. 1988;Cold Spring Harbor Laboratory, New York.
22. Heery D. M., Kalkhoven E., Hoare S., Parker M. G. A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature. 387:1997;733-736.
23. Heng H. H. Q., Squire J., Tsui L. C. High-resolution mapping of mammalian genes by in situ hybridization to free chromatin. Proc. Natl. Acad. Sci. USA. 89:1992;9509-9513.
24. Heng H. H. Q., Tsui L. C. Modes of DAPI banding and simultaneous in situ hybridization. Chromosoma. 102:1993;325-332.
25. Huang N., Vom Baur E., Garnier J. M., Lerouge T., Vonesch J. L., Lutz Y., Chambon P., Losson R. Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO J. 17:1998;3398-3412.
26. Jans D. A. The regulation of protein transport to the nucleus by phosphorylation. Biochem. J. 311:1995;705-716.
27. Katsumoto T., Higaki K., Ohno K., Onodera K. Cell-cycle dependent biosynthesis and localization of p53 protein in untransformed human cells. Biol. Cell. 84:1995;167-173.
28. Klotzsche O., Etzrodt D., Hohenberg H., Bohn W., Deppert W. Cytoplasmic retention of mutant tsp53 is dependent on an intermediate filament protein (vimentin) scaffold. Oncogene. 16:1998;3423-3434.
29. Kozak M. Structural features in eukaryotic mRNAs that modulate the initiation of translation. J. Biol. Chem. 266:1991;19867-19870.
30. Kyte J., Doolittle R. F. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:1982;105-132.
31. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
32. Lagnado C. A., Brown C. Y., Goodall G. J. AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: The functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A). Mol. Cell. Biol. 14:1994;7984-7995.
33. Madan A. P., DeFranco D. B. Bidirectional transport of glucocorticoid receptors across the nuclear envelope. Proc. Natl. Acad. Sci. USA. 90:1993;3588-3592.
34. Middeler G., Zerf K., Jenovai S., Thulig A., Tschodrich-Rotter M., Kubitscheck U., Peters R. The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited. Oncogene. 14:1997;1407-1417.
35. Mullokandov M. R., Kholodilov N. G., Atkin N. B., Burk R. D., Johnson A. B., Klinger H. P. Genomic alterations in cervical carcinoma: Losses of chromosome heterozygosity and human papilloma virus tumor status. Cancer Res. 56:1996;197-205.
36. Pines J., Hunter T. The differential localization of human cyclins A and B is due to a cytoplasmic retention signal in cyclin B. EMBO J. 13:1994;3772-3781.
37. Polascik T. J., Cairns P., Chang W. Y. H., Schoenberg M. P., Sidransky D. Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma. Cancer Res. 55:1995;5396-5399.
38. Quek H. H., Chow V. T. K. Genomic organization and mapping of the human HEP-COP gene (COPA) to 1q. Cytogenet. Cell Genet. 76:1997a;139-143.
39. Quek H. H., Chow V. T. K. Molecular and cellular studies of the human homolog of the 160-kD α-subunit of the coatomer protein complex. DNA Cell Biol. 16:1997b;275-280.
40. Reeves W. H., Sthoeger Z. M. Molecular cloning of cDNA encoding the p70 (Ku) lupus autoantigen. J. Biol. Chem. 264:1989;5047-5052.
41. Rihs H. P., Jans D. A., Fan H., Peters R. The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen. EMBO J. 10:1991;633-639.
42. Schwab M. S., Dreyer C. Protein phosphorylation sites regulate the function of the bipartite NLS of nucleolin. Eur. J. Cell Biol. 73:1997;287-297.
43. Shaulsky G., Ben-Ze'ev A., Rotter V. Subcellular distribution of the p53 protein during the cell cycle of Balb/c 3T3 cells. Oncogene. 5:1990;1707-1711.
44. Shaw G., Kamen R. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell. 46:1986;659-667.
45. Sigler P. B. Acid blobs and negative noodles. Nature. 333:1988;210-212.
46. Solomon M. J. Activation of the various cyclin/cdc2 protein kinases. Curr. Opin. Cell Biol. 5:1993;180-186.
47. Taagepera S., McDonald D., Loeb J. E., Whitaker L. L., McElroy A. K., Wang J. Y. J., Hope T. J. Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase. Proc. Natl. Acad. Sci. USA. 95:1998;7457-7462.
48. Tacke R., Goridis C. Alternative splicing in the neural cell adhesion molecule pre-mRNA: Regulation of exon 18 skipping depends on the 5′-splice site. Genes Dev. 5:1991;1416-1429.
49. Takahashi K., Suzuki K. DNA synthesis-associated nuclear exclusion of p53 in normal breast epithelial cells in culture. Oncogene. 9:1994;183-188.
50. Takeuchi M., Yanagida M. A mitotic role for a novel fission yeast protein-kinase dsk1 with cell-cycle stage dependent phosphorylation and localization. Mol. Biol. Cell. 4:1993;247-260.
51. Tamura G., Sakata K., Nishizuka S., Maesawa C., Suzuki Y., Terashima M., Eda Y., Satodate R. Allelotype of adenoma and differentiated adenocarcinoma of the stomach. J. Pathol. 180:1996;371-377.
52. Tanguay R. L., Gallie D. R. Translational efficiency is regulated by the length of the 3′ untranslated region. Mol. Cell. Biol. 16:1996;146-156.
53. Tirkkonen M., Johannsson O., Agnarsson B. A., Olsson H., Ingvarsson S., Karhu R., Tanner M., Isola J., Barkardottir R. B., Borg A., Kallioniemi O. P. Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations. Cancer Res. 57:1997;1222-1227.
54. Torchia J., Rose D. W., Inostroza J., Kamei Y., Westin S., Glass C. K., Rosenfeld M. G. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature. 387:1997;677-684.
55. Triezenberg S. J., Kingsbury R. C., McKnight S. L. Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. Genes Dev. 2:1988;718-729.
56. Verma I. M., Stevenson J. K., Schwarz E. M., Van Antwerp D., Miyamoto S. Rel/NF-κB/IκB family: Intimate tales of association and dissociation. Genes Dev. 9:1995;2723-2735.