The role of kreisler in segmentation during hindbrain development

Developmental Biology

Volumn 211, Issue 2, 1999, Pages 220-237

  Manzanares, Miguel ^a   Trainor, Paul A ^a   Nonchev, Stefan ^a   Ariza McNaughton, Linda ^a   Brodie, Jim ^a   Gould, Alex ^a   Marshall, Heather ^a   Morrison, Alastair ^a   Kwan, Chung Tin ^b   Sham, Mai Har ^b   Wilkinson, David G ^a   Krumlauf, Robb ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b NONE

Author keywords

And Hox genes; Hindbrain; Kreisler; Segmentation; Transgenic mice

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; EMBRYO PATTERN FORMATION; EMBRYO SEGMENTATION; FEMALE; GENE EXPRESSION; IN SITU HYBRIDIZATION; MALE; MOUSE; NEUROMERE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RHOMBENCEPHALON; TRANSGENIC MOUSE;

ANIMALIA; DANIO RERIO; MUS MUSCULUS;

EID: 0033566053     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9318     Document Type: Article

References (60)

1. Bergemann A. D., Cheng H.-J., Brambilla R., Klein R., Flanagan J. G. ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites. Mol. Cell. Biol. 15:1995;4921-4929.
2. Birgbauer E., Fraser S. E. Violation of cell lineage restriction compartments in the chick hindbrain. Development. 120:1994;1347-1356.
3. Carpenter E. M., Goddard J. M., Chisaka O., Manley N. R., Capecchi M. R. Loss of Hoxa-1 (Hox-1.6) function results in the reorganization of the murine hindbrain. Development. 118:1993;1063-1075.
4. Chan W. Y., Tam P. P. L. A morphological and experimental study of the mesencephalic neural crest cells in the mouse embryo using wheat-germ agglutinin gold conjugate as the cell marker. Development. 102:1988;427-442.
5. Chisaka O., Capecchi M. Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox1.5. Nature. 350:1991;473-479.
6. Cordes S. P., Barsh G. S. The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell. 79:1994;1025-1034.
7. Davenne M., Maconochie M., Neun R., Brunet J.-F., Chambon P., Krumlauf R., Rijli F. Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain. Neuron. 22:1999;677-691.
8. Deol M. S. The abnormalities of the inner ear in kreisler mice. J. Embryol. Exp. Morphol. 12:1964;475-490.
9. Dollé P., Lufkin T., Krumlauf R., Mark M., Duboule D., Chambon P. Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos. Proc. Natl. Acad. Sci. USA. 90:1993;7666-7670.
10. Eichmann A., Grapin-Botton A., Kelly L., Graf T., Le Douarin N. M., Sieweke M. The expression pattern of the mafB/kr gene in birds and mice reveals that the kreisler phenotype does not represent a null mutant. Mech. Dev. 65:1997;111-122.
11. Ellis J., Liu Q., Breitman M., Jenkins N., Gilbert G., Copeland N., Tempest H., Warren S., Muir E., Schilling H., Fletcher F., Ziegler S., Rogers J. Embryo brain kinase: A novel gene of the Eph/Elk receptor tyrosine kinase family. Mech. Dev. 52:1995;319-349.
12. Fraser S., Keynes R., Lumsden A. Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions. Nature. 344:1990;431-435.
13. Frohman M. A., Martin G. R., Cordes S., Halamek L. P., Barsh G. S. Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant kreisler (kr). Development. 117:1993;925-936.
14. Gale N., Flenniken A., Compton D., Jenkins N., Copeland N., Gilbert D., Davis S., Wilkinson D., Yancopoulos G. Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments. Oncogene. 13:1996;1343-1352.
15. Gavalas A., Davenne M., Lumsden A., Chambon P., Rijli F. Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning. Development. 124:1997;3693-3702.
16. Gavalas A., Studer M., Lumsden A., Rijli F., Krumlauf R., Chambon P. Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch. Development. 125:1998;1123-1136.
17. Goddard J., Rossel M., Manley N., Capecchi M. Mice with targeted disruption of Hoxb1 fail to form the motor nucleus of the VIIth nerve. Development. 122:1996;3217-3228.
18. Gould A., Itasaki N., Krumlauf R. Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway. Neuron. 21:1998;39-51.
19. Gould A., Morrison A., Sproat G., White R., Krumlauf R. Positive cross-regulation and enhancer sharing: Two mechanisms for specifying overlapping Hox expression patterns. Genes Dev. 11:1997;900-913.
20. Graham A., Lumsden A. Interactions between rhombomeres modulate Krox-20 and follistatin expression in the chick embryo hindbrain. Development. 122:1996;473-480.
21. Guthrie S., Lumsden A. Formation and regeneration of rhombomere boundaries in the developing chick hindbrain. Development. 112:1991;221-229.
22. Guthrie S., Prince V., Lumsden A. Selective dispersal of avian rhombomere cells in orthotopic and heterotopic grafts. Development. 118:1993;527-538.
23. Hertwig P. Die Genese der Hirn- und Gehörorganmiβbildungen bei röntgenmutierten Kreisler-mäusen. Z. KonstLehnre. 28:1944;327-354.
24. Jacobson A. G., Tam P. P. L. Cephalic neurulation in the mouse embryo analyzed by sem and morphometry. Anat. Rec. 203:1982;375-396.
25. Lumsden A., Krumlauf R. Patterning the vertebrate neuraxis. Science. 274:1996;1109-1115.
26. Maconochie M., Nonchev S., Studer M., Chan S.-K., Pöpperl H., Sham M.-H., Mann R., Krumlauf R. Cross-regulation in the mouse HoxB complex: The expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1. Genes Dev. 11:1997;1885-1896.
27. Maconochie M. K., Nonchev S., Morrison A., Krumlauf R. Paralogous Hox genes: Function and regulation. Annu. Rev. Genet. 30:1996;529-556.
28. Manzanares M., Cordes S., Ariza-McNaughton L., Sadl V., Maruthainar K., Barsh G., Krumlauf R. Conserved and distinct roles of kreisler in regulation of the paralogous Hoxa3 and Hoxb3 genes. Development. 126:1999;759-769.
29. Manzanares M., Cordes S., Kwan C.-T., Sham M.-H., Barsh G., Krumlauf R. Segmental regulation of Hoxb3 by kreisler. Nature. 387:1997;191-195.
30. Mark M., Lufkin T., Vonesch J.-L., Ruberte E., Olivo J.-C., Dollé P., Gorry P., Lumsden A., Chambon P. Two rhombomeres are altered in Hoxa-1 mutant mice. Development. 119:1993;319-338.
31. Marshall H., Nonchev S., Sham M. H., Muchamore I., Lumsden A., Krumlauf R. Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity. Nature. 360:1992;737-741.
32. McKay I., Lewis J., Lumsden A. Organization and development of facial motor neurons in the kreisler mutant mouse. Eur. J. Neurosci. 9:1997;1499-1506.
33. McKay I. J., Muchamore I., Krumlauf R., Maden M., Lumsden A., Lewis J. The kreisler mouse: A hindbrain segmentation mutant that lacks two rhombomeres. Development. 120:1994;2199-2211.
34. Moens C. B., Cordes S. P., Giorgianni M. W., Barsh G. S., Kimmel C. B. Equivalence in the genetic control of hindbrain segmentation in fish and mouse. Development. 125:1998;381-391.
35. Moens C. B., Yan Y.-L., Appel B., Force A. G., Kimmel C. B. valentino: A zebrafish gene required for normal hindbrain segmentation. Development. 122:1996;3981-3990.
36. Nichols D. Neural crest formation in the head of the mouse embryo as observed using a new histological technique. JEEM. 64:1981;105-120.
37. Nieto M. A., Bradley L. C., Wilkinson D. G. Conserved segmental expression of Krox-20 in the vertebrate hindbrain and its relationship to lineage restriction. Development Suppl. 2:1991;59-62.
38. Nonchev S., Vesque C., Maconochie M., Seitanidou T., Ariza-McNaughton L., Frain M., Marshall H., Sham M. H., Krumlauf R., Charnay P. Segmental expression of Hoxa-2 in the hindbrain is directly regulated by Krox-20. Development. 122:1996;543-554.
39. Pattyn A., Morin X., Cremer H., Goridis C., Brunet J.-F. Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development. 124:1997;4065-4075.
40. Prince V. E., Moens C. B., Kimmel C. B., Ho R. K. Zebrafish hox genes: Expression in the hindbrain region of wild-type and mutants of the segmentation gene, valentino. Development. 125:1998;393-406.
41. Schneider-Maunoury S., Seitanidou T., Charnay P., Lumsden A. Segmental and neuronal architecture of the hindbrain of Krox-20 mouse mutants. Development. 124:1997;1215-1226.
42. Schneider-Maunoury S., Topilko P., Seitanidou T., Levi G., Cohen-Tannoudji M., Pournin S., Babinet C., Charnay P. Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell. 75:1993;1199-1214.
43. Schvarzstein M., Kirn A., Haffter P., Cordes S. Expression of Zkrml2, a homologue of the Krml1/val segmentation gene, during embryonic patterning of the zebrafish (Danio rerio). Mech. Dev. 80:1999;223-226.
44. Sham M. H., Vesque C., Nonchev S., Marshall H., Frain M., Das Gupta R., Whiting J., Wilkinson D., Charnay P., Krumlauf R. The zinc finger gene Krox-20 regulates Hoxb-2 (Hox2.8) during hindbrain segmentation. Cell. 72:1993;183-196.
45. Studer M., Gavalas A., Marshall H., Ariza-McNaughton L., Rijli F., Chambon P., Krumlauf R. Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning. Development. 125:1998;1025-1036.
46. Studer M., Lumsden A., Ariza-McNaughton L., Bradley A., Krumlauf R. Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1. Nature. 384:1996;630-635.
47. Sturm K., Tam P. P. L. Isolation and culture of whole postimplantation embryos and germ layer derivatives. Methods Enzymol. 225:1993;164-190.
48. Swiatek P. J., Gridley T. Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox-20. Genes Dev. 7:1993;2071-2084.
49. Theil T., Ariza-McNaughton L., Manzanares M., Krumlauf R., Wilkinson D. kreisler regulates rostrocaudal identity in the hindbrain. Development. 1999.
50. Theil T., Frain M., Gilardi-Hebenstreit P., Flenniken A., Charnay P., Wilkinson D. Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under the direct transcriptional control of Krox20. Development. 125:1998;443-452.
51. Trainor P. A., Tam P. P. L. Cranial paraxial mesoderm and neural crest of the mouse embryo-codistribution in the craniofacial mesenchyme but distinct segregation in the branchial arches. Development. 121:1995;2569-2582.
52. Trainor P. A., Tan S. S., Tam P. P. L. Cranial paraxial mesoderm-regionalization of cell fate and impact on craniofacial development in mouse embryos. Development. 120:1994;2925-2932.
53. Whiting J., Marshall H., Cook M., Krumlauf R., Rigby P. W. J., Stott D., Allemann R. K. Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes Dev. 5:1991;2048-2059.
54. Wilkinson D. G., Bhatt S., Chavrier P., Bravo R., Charnay P. Segment-specific expression of a zinc finger gene in the developing nervous system of the mouse. Nature. 337:1989;461-464.
55. Wittbrodt J., Meyer A., Schartl M. More genes in fish. Bioessays. 20:1998;511-515.
56. Wizenmann A., Lumsden A. Segregation of rhombomeres by differential chemoaffinity. Mol. Cell. Neurosci. 9:1997;448-459.
57. Xu Q., Alldus G., Holder N., Wilkinson D. G. Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain. Development. 121:1995;4005-4016.
58. Xu Q., Mellitzer G., Robinson V., Wilkinson D. In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins. Nature. 399:1999;267-271.
59. Xu Q., Wilkinson D. In Situ Hybridisation of mRNA with Hapten Labelled Probes. 1998;IRL Press, Oxford.
60. Zhang M., Kim H.-J., Marshall H., Gendron-Maguire M., Lucas A. D., Baron A., Gudas L. J., Gridley T., Krumlauf R., Grippo J. F. Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain. Development. 120:1994;2431-2442.