메뉴 건너뛰기




Volumn 122, Issue 10, 1996, Pages 3217-3228

Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve

Author keywords

Bell's Palsy; Facial nerve; Gene targeting; Homeobox genes; Hox genes; hoxb 1; Moebius Syndrome; Mouse development

Indexed keywords

HOMEODOMAIN PROTEIN;

EID: 0029824070     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (261)

References (57)
  • 1
    • 0020015917 scopus 로고
    • Development of the cranial nerve ganglia and related nuclei in the rat
    • New York: Springer-Verlag
    • Altman, J. and Bayer, S. (1982). Development of the cranial nerve ganglia and related nuclei in the rat. In Advances in Anatomy, Embryology and Cell Biology, 74, pp. 1-90. New York: Springer-Verlag.
    • (1982) Advances in Anatomy, Embryology and Cell Biology , vol.74 , pp. 1-90
    • Altman, J.1    Bayer, S.2
  • 2
    • 0020371498 scopus 로고
    • Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposen Tn5
    • Beck, E., Ludwig, G., Auserwald, E. A., Reiss, B. and Schaller, H. (1982). Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposen Tn5. Gene 19, 327-336.
    • (1982) Gene , vol.19 , pp. 327-336
    • Beck, E.1    Ludwig, G.2    Auserwald, E.A.3    Reiss, B.4    Schaller, H.5
  • 3
    • 0030578422 scopus 로고    scopus 로고
    • Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
    • Boulet, A. M. and Capecchi, M. R. (1996). Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations. Dev. Biol. 177, 232-249.
    • (1996) Dev. Biol. , vol.177 , pp. 232-249
    • Boulet, A.M.1    Capecchi, M.R.2
  • 4
    • 0001995702 scopus 로고    scopus 로고
    • The role of Hox genes in hindbrain development
    • (ed.W. M. Cowan, T. M. Jessell and S. L. Zipursky), New York: Oxford University Press. In press
    • Capecchi, M. R. (1997). The role of Hox genes in hindbrain development. In Molecular and Cellular Aspects of Neural Development. (ed.W. M. Cowan, T. M. Jessell and S. L. Zipursky), New York: Oxford University Press. In press.
    • (1997) Molecular and Cellular Aspects of Neural Development
    • Capecchi, M.R.1
  • 5
    • 0027249799 scopus 로고
    • Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the marine hindbrain
    • Carpenter, E. M., Goddard, J. M., Chisaka, O., Manley, N. R. and Capecchi, M. R. (1993). Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the marine hindbrain. Development 118, 1063-1075.
    • (1993) Development , vol.118 , pp. 1063-1075
    • Carpenter, E.M.1    Goddard, J.M.2    Chisaka, O.3    Manley, N.R.4    Capecchi, M.R.5
  • 6
    • 0025797513 scopus 로고
    • Regionally restricted developmental detects resulting from targeted disruption of the mouse homeobox gene hox-1.5
    • Chisaka, O. and Capecchi, M. R. (1991). Regionally restricted developmental detects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature 350, 473-479.
    • (1991) Nature , vol.350 , pp. 473-479
    • Chisaka, O.1    Capecchi, M.R.2
  • 7
    • 0026599290 scopus 로고
    • Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6
    • Chisaka, O., Musci, T. S. and Capecchi, M. R. (1992). Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6. Nature 355, 516-520.
    • (1992) Nature , vol.355 , pp. 516-520
    • Chisaka, O.1    Musci, T.S.2    Capecchi, M.R.3
  • 8
    • 0028085623 scopus 로고
    • Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11
    • Davis, A. P. and Capecchi, M. R. (1994). Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Development 120, 2187-2198.
    • (1994) Development , vol.120 , pp. 2187-2198
    • Davis, A.P.1    Capecchi, M.R.2
  • 9
    • 0029026767 scopus 로고
    • Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11
    • Davis, A. P., Witte, D. P., Hsieh-Li, H. M., Potter, S. S. and Capecchi, M. R. (1995). Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11. Nature 375, 791-795.
    • (1995) Nature , vol.375 , pp. 791-795
    • Davis, A.P.1    Witte, D.P.2    Hsieh-Li, H.M.3    Potter, S.S.4    Capecchi, M.R.5
  • 10
    • 0029963585 scopus 로고    scopus 로고
    • A mutational analysis of the 5′ Hox D genes: Dissection of genetic interactions during limb development in the mouse
    • Davis, A. P. and Capecchi, M. R. (1996). A mutational analysis of the 5′ Hox D genes: Dissection of genetic interactions during limb development in the mouse. Development 122, 1175-1185.
    • (1996) Development , vol.122 , pp. 1175-1185
    • Davis, A.P.1    Capecchi, M.R.2
  • 11
    • 0023986284 scopus 로고
    • Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons
    • Dodd, J., Morton, S. B., Karagogeos, D., Yamamoto, M. and Jessell, T. M. (1988). Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron 1, 105-116.
    • (1988) Neuron , vol.1 , pp. 105-116
    • Dodd, J.1    Morton, S.B.2    Karagogeos, D.3    Yamamoto, M.4    Jessell, T.M.5
  • 12
    • 0024788839 scopus 로고
    • Coordinate expression of the murine Hox-5 complex homeobox-containing genes during limb pattern formation
    • Dollé, P., Izpisúa-Belmonte, J.-C., Falkenstein, H., Renucci, A. and Duboule, D. (1989). Coordinate expression of the murine Hox-5 complex homeobox-containing genes during limb pattern formation. Nature 342, 767-772.
    • (1989) Nature , vol.342 , pp. 767-772
    • Dollé, P.1    Izpisúa-Belmonte, J.-C.2    Falkenstein, H.3    Renucci, A.4    Duboule, D.5
  • 13
    • 0026326323 scopus 로고
    • The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development
    • Dollé, P., Izpisúa-Belmonte, J.-C., Boncinelli, E. and Duboule, D. (1991). The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development. Mech. Dev. 36, 3-13.
    • (1991) Mech. Dev. , vol.36 , pp. 3-13
    • Dollé, P.1    Izpisúa-Belmonte, J.-C.2    Boncinelli, E.3    Duboule, D.4
  • 14
    • 0027358721 scopus 로고
    • Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs
    • Dollé, P., Dierich, A., LeMeur, M., Schimmang, T., Schuhbaur, B., Chambon, P. and Duboule, D. (1993). Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell 75, 431-441.
    • (1993) Cell , vol.75 , pp. 431-441
    • Dollé, P.1    Dierich, A.2    Lemeur, M.3    Schimmang, T.4    Schuhbaur, B.5    Chambon, P.6    Duboule, D.7
  • 15
    • 0024341769 scopus 로고
    • The structural and functional organization of the murine Hox gene family resembles that of Drosophila homeotic genes
    • Duboule, D. and Dollé, P. (1989). The structural and functional organization of the murine Hox gene family resembles that of Drosophila homeotic genes. EMBO J. 8, 1497-1505.
    • (1989) EMBO J. , vol.8 , pp. 1497-1505
    • Duboule, D.1    Dollé, P.2
  • 17
    • 0030019608 scopus 로고    scopus 로고
    • Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton
    • Favier, B., Rijli, F. M., Fromental-Ramain, C., Fraulob, V. and Chambon, P. (1996). Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton. Development 122, 449-460.
    • (1996) Development , vol.122 , pp. 449-460
    • Favier, B.1    Rijli, F.M.2    Fromental-Ramain, C.3    Fraulob, V.4    Chambon, P.5
  • 18
    • 0025066238 scopus 로고
    • Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm
    • Frohman, M. A., Boyle, M. and Martin, G. R. (1990). Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm. Development 110, 589-607.
    • (1990) Development , vol.110 , pp. 589-607
    • Frohman, M.A.1    Boyle, M.2    Martin, G.R.3
  • 20
    • 0027759447 scopus 로고
    • Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest
    • Gendron-Maguire, M., Mallo, M., Zhang, M. and Gridley, T. (1993). Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell 75, 1317-1331.
    • (1993) Cell , vol.75 , pp. 1317-1331
    • Gendron-Maguire, M.1    Mallo, M.2    Zhang, M.3    Gridley, T.4
  • 21
    • 0024589805 scopus 로고
    • The murine and Drosophila homeobox gene complexes have common features of organization and expression
    • Graham, A., Papalopulu, N. and Krumlauf, R. (1989). The murine and Drosophila homeobox gene complexes have common features of organization and expression. Cell 57, 367-378.
    • (1989) Cell , vol.57 , pp. 367-378
    • Graham, A.1    Papalopulu, N.2    Krumlauf, R.3
  • 22
    • 0029143166 scopus 로고
    • Compound mutants for the paralogous hoxa-4, hoxh-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed
    • Horan, G. S. B., Ramírez-Solis, R., Featherstone, M. S., Wolgemuth, D. J., Bradley, A. and Behringer, R. R. (1995). Compound mutants for the paralogous hoxa-4, hoxh-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed. Genes Dev. 9, 1667-1677.
    • (1995) Genes Dev. , vol.9 , pp. 1667-1677
    • Horan, G.S.B.1    Ramírez-Solis, R.2    Featherstone, M.S.3    Wolgemuth, D.J.4    Bradley, A.5    Behringer, R.R.6
  • 24
    • 0025785350 scopus 로고
    • Murine genes related to the Drosophila AbdB homeotic gene are sequentially expressed during development of the posterior part of the body
    • Izpisúa-Belmonte, J,-C., Falkenstein, H., Dollé, P., Renucci, A. and Duboule, D. (1991). Murine genes related to the Drosophila AbdB homeotic gene are sequentially expressed during development of the posterior part of the body. EMBO J. 10, 2279-2289.
    • (1991) EMBO J. , vol.10 , pp. 2279-2289
    • Izpisúa-Belmonte, J.-C.1    Falkenstein, H.2    Dollé, P.3    Renucci, A.4    Duboule, D.5
  • 25
    • 0027517719 scopus 로고
    • Specification of axial identity in the mouse: Role of the Hoxa-5 (Hox-1.3) gene
    • Jeannotte, L., Lemieux, M., Charron, J., Poirier, F. and Robertson, E. J. (1993). Specification of axial identity in the mouse: role of the Hoxa-5 (Hox-1.3) gene. Genes Dev. 7, 2085-2096.
    • (1993) Genes Dev. , vol.7 , pp. 2085-2096
    • Jeannotte, L.1    Lemieux, M.2    Charron, J.3    Poirier, F.4    Robertson, E.J.5
  • 26
    • 0028226038 scopus 로고
    • Targeted disruptions of the murine hoxa-4 and hoxa-6 genes result in homeotic transformations of components of the vertebral column
    • Kostic, D. and Capecchi, M. R. (1994). Targeted disruptions of the murine hoxa-4 and hoxa-6 genes result in homeotic transformations of components of the vertebral column. Mech. Dev. 46, 231-247.
    • (1994) Mech. Dev. , vol.46 , pp. 231-247
    • Kostic, D.1    Capecchi, M.R.2
  • 27
    • 0025122294 scopus 로고
    • Moebius syndrome
    • Kumar, D. (1990). Moebius syndrome. J. Med. Genet.27, 122-126.
    • (1990) J. Med. Genet. , vol.27 , pp. 122-126
    • Kumar, D.1
  • 28
    • 0026602808 scopus 로고
    • Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene
    • LeMouellic, H., Lallemand, Y. and Brûlet, P. (1992). Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene. Cell 69, 251-264.
    • (1992) Cell , vol.69 , pp. 251-264
    • Lemouellic, H.1    Lallemand, Y.2    Brûlet, P.3
  • 29
    • 0018240421 scopus 로고
    • A gene complex controlling segmentation in Drosophila
    • Lewis, E. B. (1978). A gene complex controlling segmentation in Drosophila. Nature 276, 565-570.
    • (1978) Nature , vol.276 , pp. 565-570
    • Lewis, E.B.1
  • 30
    • 0025864268 scopus 로고
    • Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression
    • Lufkin, T., Dierich, A., LeMeur, M., Mark, M. and Chambon, P. (1991). Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression. Cell 66, 1105-1119.
    • (1991) Cell , vol.66 , pp. 1105-1119
    • Lufkin, T.1    Dierich, A.2    Lemeur, M.3    Mark, M.4    Chambon, P.5
  • 31
    • 0024548307 scopus 로고
    • Segmental patterns of neuronal development in the chick hindbrain
    • Lumsden, A. and Keynes, R. (1989). Segmental patterns of neuronal development in the chick hindbrain. Nature 337, 424-428.
    • (1989) Nature , vol.337 , pp. 424-428
    • Lumsden, A.1    Keynes, R.2
  • 32
    • 0026545660 scopus 로고
    • Domains of cellular retinoic acid-binding protein I (CRA BP I) expression in the hindbrain and neural crest of the mouse embryo
    • Maden, M., Horton, C., Graham, A., Leonard, L., Pizzey, J., Siegenthaler, G., Lumsden, A. and Eriksson, U. (1992). Domains of cellular retinoic acid-binding protein I (CRA BP I) expression in the hindbrain and neural crest of the mouse embryo. Mech. Dev. 37, 13-23.
    • (1992) Mech. Dev. , vol.37 , pp. 13-23
    • Maden, M.1    Horton, C.2    Graham, A.3    Leonard, L.4    Pizzey, J.5    Siegenthaler, G.6    Lumsden, A.7    Eriksson, U.8
  • 33
    • 0029030722 scopus 로고
    • The role of hoxa-3 in mouse thymus and thyroid development
    • Manley, N. R. and Capecchi, M. R. (1995). The role of hoxa-3 in mouse thymus and thyroid development. Development 121, 1989-2003.
    • (1995) Development , vol.121 , pp. 1989-2003
    • Manley, N.R.1    Capecchi, M.R.2
  • 34
    • 0024296027 scopus 로고
    • Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes
    • Mansour, S. L., Thomas, K. R. and Capecchi, M. R. (1988). Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes. Nature 336, 348-352.
    • (1988) Nature , vol.336 , pp. 348-352
    • Mansour, S.L.1    Thomas, K.R.2    Capecchi, M.R.3
  • 35
    • 0027500633 scopus 로고
    • Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear
    • Mansour, S. L., Goddard, J. M. and Capecchi, M. R. (1993). Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development 117, 13-28.
    • (1993) Development , vol.117 , pp. 13-28
    • Mansour, S.L.1    Goddard, J.M.2    Capecchi, M.R.3
  • 37
    • 0027103903 scopus 로고
    • Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity
    • Marshall, H., Nonchev, S., Sham, M. H., Muchamore, I., Lumsden, A. and Krumlauf, R. (1992). Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity. Nature 360, 737-741.
    • (1992) Nature , vol.360 , pp. 737-741
    • Marshall, H.1    Nonchev, S.2    Sham, M.H.3    Muchamore, I.4    Lumsden, A.5    Krumlauf, R.6
  • 38
    • 0026008034 scopus 로고
    • Expression of the mouse labial-like homeobox-containing genes, Hox-2.9 and Hox-1.6. during segmentation of the hindbrain
    • Murphy, P. and Hill, R. E. (1991). Expression of the mouse labial-like homeobox-containing genes, Hox-2.9 and Hox-1.6. during segmentation of the hindbrain. Development 111, 61-74.
    • (1991) Development , vol.111 , pp. 61-74
    • Murphy, P.1    Hill, R.E.2
  • 39
    • 0027321548 scopus 로고
    • Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
    • Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W. and Roder, J. C. (1993). Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc: Natl. Acad. Sci. USA 90, 8424-8428.
    • (1993) Proc: Natl. Acad. Sci. USA , vol.90 , pp. 8424-8428
    • Nagy, A.1    Rossant, J.2    Nagy, R.3    Abramow-Newerly, W.4    Roder, J.C.5
  • 40
    • 0029055810 scopus 로고
    • Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
    • Pöpperl, H., Bienz, M., Studer, M., Chan, S.-K., Aparicio, S., Brenner, S., Mann, R. S. and Krumlauf, R. (1995). Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 81, 1031-1042.
    • (1995) Cell , vol.81 , pp. 1031-1042
    • Pöpperl, H.1    Bienz, M.2    Studer, M.3    Chan, S.-K.4    Aparicio, S.5    Brenner, S.6    Mann, R.S.7    Krumlauf, R.8
  • 41
    • 0027189536 scopus 로고
    • Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments
    • Ramirez-Solis, R., Zheng, H., Whiting, J., Krumlauf, R. and Bradley, A. (1993). Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments. Cell 73, 279-294.
    • (1993) Cell , vol.73 , pp. 279-294
    • Ramirez-Solis, R.1    Zheng, H.2    Whiting, J.3    Krumlauf, R.4    Bradley, A.5
  • 42
    • 0028859990 scopus 로고
    • Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation
    • Rancourt, D. E., Tsuzuki, T. and Capecchi, M. R. (1995). Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. Genes Dev. 9, 108-122.
    • (1995) Genes Dev. , vol.9 , pp. 108-122
    • Rancourt, D.E.1    Tsuzuki, T.2    Capecchi, M.R.3
  • 43
    • 0027739813 scopus 로고
    • A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene
    • Rijli, F. M., Mark, M., Lakkaraju, S., Dierich, A., Dollé, P. and Chambon, P. (1993). A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene. Cell 75, 1333-1349.
    • (1993) Cell , vol.75 , pp. 1333-1349
    • Rijli, F.M.1    Mark, M.2    Lakkaraju, S.3    Dierich, A.4    Dollé, P.5    Chambon, P.6
  • 44
    • 0028875032 scopus 로고
    • Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalisation of the chick hindgut
    • Roberts, D. J., Johnson, R. L., Burke, A. C., Nelson, C. E., Morgan, B. A. and Tabin, C. (1995). Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalisation of the chick hindgut. Developmant 121, 3163-3174.
    • (1995) Developmant , vol.121 , pp. 3163-3174
    • Roberts, D.J.1    Johnson, R.L.2    Burke, A.C.3    Nelson, C.E.4    Morgan, B.A.5    Tabin, C.6
  • 45
    • 0028926210 scopus 로고
    • Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice
    • Satokata, I., Benson, G. and Maas, R. (1995). Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice. Nature 374, 460-463.
    • (1995) Nature , vol.374 , pp. 460-463
    • Satokata, I.1    Benson, G.2    Maas, R.3
  • 47
    • 0026487321 scopus 로고
    • Vital dye analysis of cranial neural crest cell migration in the mouse embryo
    • Serbedzija, G. N., Bronner-Fraser, M. and Fraser, S. E. (1992). Vital dye analysis of cranial neural crest cell migration in the mouse embryo. Development 116, 297-307.
    • (1992) Development , vol.116 , pp. 297-307
    • Serbedzija, G.N.1    Bronner-Fraser, M.2    Fraser, S.E.3
  • 48
    • 0027131262 scopus 로고
    • Homeotic transformations and limb defects in HaxA-11 mutant mice
    • Small, K. M. and Potter, S. S. (1993). Homeotic transformations and limb defects in HaxA-11 mutant mice. Genes Dev. 7, 2318-2328.
    • (1993) Genes Dev. , vol.7 , pp. 2318-2328
    • Small, K.M.1    Potter, S.S.2
  • 49
    • 0023806075 scopus 로고
    • Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
    • Smith, D. B. and Johnson, K. S. (1988). Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67, 31-40.
    • (1988) Gene , vol.67 , pp. 31-40
    • Smith, D.B.1    Johnson, K.S.2
  • 50
    • 0029035611 scopus 로고
    • Hoxc-9 mutant mice show anterior transformation of the vertebrae and malformation of the sternum und ribs
    • Suemori, W., Takahashi, N. and Noguchi, S. (1995). Hoxc-9 mutant mice show anterior transformation of the vertebrae and malformation of the sternum und ribs. Mech. Dev. 51, 265-273.
    • (1995) Mech. Dev. , vol.51 , pp. 265-273
    • Suemori, W.1    Takahashi, N.2    Noguchi, S.3
  • 51
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • Thomas, K. R. and Capecchi, M. R. (1987). Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51, 503-512.
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 52
    • 0026770668 scopus 로고
    • High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors
    • Thomas, K. R., Deng, C. and Capecchi, M. R. (1992). High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Mol. Cell. Biol. 12, 2919-2923.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2919-2923
    • Thomas, K.R.1    Deng, C.2    Capecchi, M.R.3
  • 53
    • 0026684136 scopus 로고
    • Expression and modification of hox-2.1 protein in mouse embryos
    • Wall, N. A., Jones, C. M., Hogan, B. L. M. and Wright, C. V. E. (1992). Expression and modification of hox-2.1 protein in mouse embryos. Mech. Dev. 37, 111-120.
    • (1992) Mech. Dev. , vol.37 , pp. 111-120
    • Wall, N.A.1    Jones, C.M.2    Hogan, B.L.M.3    Wright, C.V.E.4
  • 54
    • 0024597579 scopus 로고
    • Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse
    • Wilkinson, D. G., Bhatt, S., Chavrier, P., Bravo, R. and Charnay, P. (1989a). Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse. Nature 337, 461-464.
    • (1989) Nature , vol.337 , pp. 461-464
    • Wilkinson, D.G.1    Bhatt, S.2    Chavrier, P.3    Bravo, R.4    Charnay, P.5
  • 55
    • 0024430616 scopus 로고
    • Segmental expression of Hox-2 homeobox-containing genes in the developing mouse hindbrain
    • Wilkinson, D. G., Bhatt, S., Cook, M., Boncinelli, E. and Krumlauf, R. (1989b). Segmental expression of Hox-2 homeobox-containing genes in the developing mouse hindbrain. Nature 341, 405-409.
    • (1989) Nature , vol.341 , pp. 405-409
    • Wilkinson, D.G.1    Bhatt, S.2    Cook, M.3    Boncinelli, E.4    Krumlauf, R.5
  • 56
    • 0025820077 scopus 로고
    • Homeobox gene expression correlated with the bifurcation process of limb cartilage development
    • Yokouchi, Y., Sasaki, H. and Kuroiwa, A. (1991). Homeobox gene expression correlated with the bifurcation process of limb cartilage development. Nature 353, 443-445.
    • (1991) Nature , vol.353 , pp. 443-445
    • Yokouchi, Y.1    Sasaki, H.2    Kuroiwa, A.3
  • 57
    • 0028973404 scopus 로고
    • Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds
    • Yokouchi, Y., Nakazato, S., Yamamoto, M., Goto, Y., Kameda, T., Iba, H. and Kuroiwa, A. (1995). Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds. Genes Dev. 9, 2509-2522.
    • (1995) Genes Dev. , vol.9 , pp. 2509-2522
    • Yokouchi, Y.1    Nakazato, S.2    Yamamoto, M.3    Goto, Y.4    Kameda, T.5    Iba, H.6    Kuroiwa, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.