Protein kinase C ligands based on tetrahydrofuran templates containing a new set of phorbol ester pharmacophores

Journal of Medicinal Chemistry

Volumn 42, Issue 20, 1999, Pages 4129-4139

  Lee, Jeewoo ^a   Kang, Ji Hye ^a   Lee, Sang Yoon ^a   Han, Kee Chung ^a   Torres, Christina M ^b   Bhattacharyya, Dipak K ^b   Blumberg, Peter M ^b   Marquez, Victor E ^a  

^a Seoul National University   (South Korea)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL DERIVATIVE; GLYCEROL; LIGAND; PHORBOL DIACETATE; PHORBOL DIBUTYRATE; PHORBOL ESTER DERIVATIVE; PROTEIN KINASE C; TETRAHYDROFURAN DERIVATIVE;

ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PHARMACOPHORE;

FURANS; ISOENZYMES; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PHORBOL 12,13-DIBUTYRATE; PHORBOL ESTERS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033533804     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980713g     Document Type: Article

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