Synthesis of bis-γ-butyrolactones containing conformationally constrained (S)- and (R)-diacylglycerol structures

Bioorganic and Medicinal Chemistry

Volumn 4, Issue 8, 1996, Pages 1299-1305

  Jeewoo, Lee ^a   Lewin, Nancy E ^a   Blumberg, Peter M ^a   Marquez, Victor E ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL DERIVATIVE; GAMMA BUTYROLACTONE DERIVATIVE; PROTEIN KINASE C;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENZYME BINDING; NONHUMAN; STEREOCHEMISTRY;

EID: 0030220250     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/0968-0896(96)00116-2     Document Type: Article

References (14)

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3. 3. Sharma, R.; Lee, J.; Wang, S.; Milne, G. W. A.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. J. Med. Chem. 1996, 39, 19.
4. 4. Lee, J.; Wang, S.; Milne, G. W. A.; Sharma, R.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E. J. Med. Chem. 1996, 39, 29.
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6. 6. Lee, J.; Teng, K.; Marquez, V. E. Tetrahedron Lett. 1992, 33, 1539.
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9. 9. Lee, J.; Marquez, V. E.; Lewin, N. E.; Blumberg, P. M. Synlett 1994, 206.
10. 10. Obtained from Pfanstiehl Laboratories, Inc. Waukegan, IL.
11. 11. Teng, K.; Marquez, V. E.; Milne, G. W. A.; Barchi, Jr. J. J.; Kazanietz, M. G.; Lewin, N. E.; Blumberg, P. M.; Abushanab, E. J. Am. Chem. Soc. 1992, 114, 1059.
12. 12. Kazanietz, M. G.; Areces, L. B.; Bahador, A.; Mischak, H.; Goodnight, J.; Mushinski, J. F.; Blumberg, P. M. Mol. Pharmacol. 1993, 44, 298.
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14. 14. Ezekiel, A. D.; Overend, W. G.; Williams, N. R. Tetrahedron Lett. 1969, 1635.