Antibody binding defines a structure for an epitope that participates in the PrP(C)→PrP(Sc) conformational change

Journal of Molecular Biology

Volumn 293, Issue 4, 1999, Pages 855-863

  Kanyo, Zoltan F ^a   Pan, Keh Ming ^b   Williamson, R Anthony ^c   Burton, Dennis R ^c   Prusiner, Stanley B ^a   Fletterick, Robert J ^d   Cohen, Fred E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antibody; Epitope; Prion; X ray; loop

Indexed keywords

EPITOPE; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; PRION PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; COMPLEMENTARITY DETERMINING REGION; CONFORMATIONAL TRANSITION; HYDROGEN BOND; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ANIMALIA; CRICETINAE; MESOCRICETUS AURATUS;

EID: 0033527583     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3193     Document Type: Article

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