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Volumn 64, Issue 1, 1998, Pages 6-13

Small molecule inhibitor of HIV-1 cell fusion blocks chemokine receptor- mediated function

Author keywords

Anti HIV 1; Chemokine inhibitor; Chemokine receptor internalization

Indexed keywords

2,2' [4,4' [(AMINOCARBONYL)AMINO]BIS[N 4' DI(PYRROLE 2 CARBOXAMIDE 1,1' DIMETHYL)] 6,8 NAPHTHALENEDISULFONIC ACID]HEXASODIUM; CHEMOKINE; CHEMOKINE RECEPTOR; DISTAMYCIN A; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG;

EID: 0031775589     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.64.1.6     Document Type: Conference Paper
Times cited : (64)

References (33)
  • 1
    • 0030183102 scopus 로고    scopus 로고
    • Chemokine receptors: Structure, function and role in microbial pathogenesis
    • Murphy, P. M. (1996) Chemokine receptors: structure, function and role in microbial pathogenesis. Cytokine. Growth Factor Rev. 7, 47-64.
    • (1996) Cytokine. Growth Factor Rev. , vol.7 , pp. 47-64
    • Murphy, P.M.1
  • 2
    • 0030825407 scopus 로고    scopus 로고
    • Chemokines
    • Rollins, B. J. (1997) Chemokines. Blood 90, 909-928.
    • (1997) Blood , vol.90 , pp. 909-928
    • Rollins, B.J.1
  • 3
    • 0029959244 scopus 로고    scopus 로고
    • The Domain on the Duffy blood group antigen for binding Plasmodium vivax and P. Knowlesi malarial parasites to erythrocytes
    • Chitnis, C. E., Chaudhuri, A., Horuk, R., Pogo, A. O., Miller, L. H. (1996) The Domain on the Duffy blood group antigen for binding Plasmodium vivax and P. Knowlesi malarial parasites to erythrocytes. J. Exp. Med. 184, 1531-1536.
    • (1996) J. Exp. Med. , vol.184 , pp. 1531-1536
    • Chitnis, C.E.1    Chaudhuri, A.2    Horuk, R.3    Pogo, A.O.4    Miller, L.H.5
  • 4
    • 0031470456 scopus 로고    scopus 로고
    • How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity
    • Dimitrov, D. S. (1997) How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity. Cell, 91, 721-730.
    • (1997) Cell , vol.91 , pp. 721-730
    • Dimitrov, D.S.1
  • 5
    • 0031025283 scopus 로고    scopus 로고
    • Pirated gene in Kaposi's sarcoma
    • Murphy, P. M. (1997) Pirated gene in Kaposi's sarcoma. Nature 385, 296-299.
    • (1997) Nature , vol.385 , pp. 296-299
    • Murphy, P.M.1
  • 6
    • 0031032769 scopus 로고    scopus 로고
    • Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation
    • Arvanitakis, L., Geras-Raaka, E., Varma, A., Gershengorn, M. C, Cesarman, E. (1997) Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation. Nature 385, 347-349.
    • (1997) Nature , vol.385 , pp. 347-349
    • Arvanitakis, L.1    Geras-Raaka, E.2    Varma, A.3    Gershengorn, M.C.4    Cesarman, E.5
  • 7
    • 0031010760 scopus 로고    scopus 로고
    • The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines
    • Lalani, A. S., Graham, K., Mossman, K., Rajarathnam, K, Clark-Lewis, I., Kelvin, D., McFadden, G. (1997) The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines. J. Virol. 71, 4356-4363.
    • (1997) J. Virol. , vol.71 , pp. 4356-4363
    • Lalani, A.S.1    Graham, K.2    Mossman, K.3    Rajarathnam, K.4    Clark-Lewis, I.5    Kelvin, D.6    McFadden, G.7
  • 8
    • 0030058539 scopus 로고    scopus 로고
    • Chemokines: Progress toward identifying molecular targets for therapeutic agents
    • Howard, O. M. Z., Ben-Baruch, A., Oppenheim, J. J. (1996) Chemokines: progress toward identifying molecular targets for therapeutic agents. Tibtech 14, 46-51.
    • (1996) Tibtech , vol.14 , pp. 46-51
    • Howard, O.M.Z.1    Ben-Baruch, A.2    Oppenheim, J.J.3
  • 9
    • 0030281494 scopus 로고    scopus 로고
    • Interleukin 8 as a novel target for intervention therapy in acute inflammatory diseases
    • Harada, A, Mukaida, N., Matsushima, K. (1996) Interleukin 8 as a novel target for intervention therapy in acute inflammatory diseases. Mol. Med. Today 2, 482-489.
    • (1996) Mol. Med. Today , vol.2 , pp. 482-489
    • Harada, A.1    Mukaida, N.2    Matsushima, K.3
  • 12
    • 0030612473 scopus 로고    scopus 로고
    • An antagonist of monocyte chemoattractant protein 1(MCP-1) inhibits arthritis in the MRL-lpr mouse model
    • Gong, J-H., Ratkay, L. G., Waterfield, J. D., Clark-Lewis, I. (1997) An antagonist of monocyte chemoattractant protein 1(MCP-1) inhibits arthritis in the MRL-lpr mouse model. J. Exp. Med. 186, 131-137.
    • (1997) J. Exp. Med. , vol.186 , pp. 131-137
    • Gong, J.-H.1    Ratkay, L.G.2    Waterfield, J.D.3    Clark-Lewis, I.4
  • 16
    • 0030773515 scopus 로고    scopus 로고
    • A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
    • Doranz, B. J., Grovit-Gerbas, K., Sharron, M. P., Mao, S-H., Goetz, M. B., Daar, E. S., Doms, R. W., O'Brien, W. A. (1997) A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor. J. Exp. Med. 186, 1395-1400.
    • (1997) J. Exp. Med. , vol.186 , pp. 1395-1400
    • Doranz, B.J.1    Grovit-Gerbas, K.2    Sharron, M.P.3    Mao, S.-H.4    Goetz, M.B.5    Daar, E.S.6    Doms, R.W.7    O'Brien, W.A.8
  • 17
    • 0030830661 scopus 로고    scopus 로고
    • Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4
    • Schols, D., Struyf, S., Van Damme, J., Este, J. A., Henson, G., De Clerq, E. (1997) Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4. J. Exp. Med. 186, 1383-1388.
    • (1997) J. Exp. Med. , vol.186 , pp. 1383-1388
    • Schols, D.1    Struyf, S.2    Van Damme, J.3    Este, J.A.4    Henson, G.5    De Clerq, E.6
  • 20
    • 0027173841 scopus 로고
    • Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120
    • Fu, Y. K., Hart, T. K., Jonak, Z. L., Bugelski, P. J. (1993) Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120. J. Virol. 67, 3818-3825.
    • (1993) J. Virol. , vol.67 , pp. 3818-3825
    • Fu, Y.K.1    Hart, T.K.2    Jonak, Z.L.3    Bugelski, P.J.4
  • 21
    • 0031962175 scopus 로고    scopus 로고
    • Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors
    • Jones, P., Korte, T., Blumenthal, R. (1998) Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors. J. Biol. Chem. 273, 404-409.
    • (1998) J. Biol. Chem. , vol.273 , pp. 404-409
    • Jones, P.1    Korte, T.2    Blumenthal, R.3
  • 22
    • 0038065763 scopus 로고    scopus 로고
    • Dilation of the HIV-1 envelope glycoprotein fusion pore revealed by the inhibiotory action of asynthetic peptide from gp41
    • in press
    • Munoz-Barroso, I., Durell, S., Sakaguchi, K., Appella, E., Blumenthal, R. (1998) Dilation of the HIV-1 envelope glycoprotein fusion pore revealed by the inhibiotory action of asynthetic peptide from gp41. J. Cell Biol., in press.
    • (1998) J. Cell Biol.
    • Munoz-Barroso, I.1    Durell, S.2    Sakaguchi, K.3    Appella, E.4    Blumenthal, R.5
  • 23
    • 0028800663 scopus 로고
    • Structural domains of interleukin-2 receptor β critical for signal transduction: Kinase association and nuclear complex-formation
    • Howard, O. M. Z., Kirken, R. A., Garcia, G. G., Hackett, R. H., Farrar, W. L. (1995) Structural domains of interleukin-2 receptor β critical for signal transduction: kinase association and nuclear complex-formation. Biochem. J. 306, 217-224.
    • (1995) Biochem. J. , vol.306 , pp. 217-224
    • Howard, O.M.Z.1    Kirken, R.A.2    Garcia, G.G.3    Hackett, R.H.4    Farrar, W.L.5
  • 24
    • 0025342694 scopus 로고
    • HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure
    • Zack, J. A., Arrigio, S. J., Weitsman, S. R., Go, A. S., Haislip, A., Chen, I. S. (1990) HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell. 61, 213-222.
    • (1990) Cell , vol.61 , pp. 213-222
    • Zack, J.A.1    Arrigio, S.J.2    Weitsman, S.R.3    Go, A.S.4    Haislip, A.5    Chen, I.S.6
  • 25
    • 0027533666 scopus 로고
    • Identification of RANTES receptors on human monocytic cells: Competition for binding and desensitization by homologous chemotactic cytokines
    • Wang, J. M., MicVicar, D. W., Oppenheim, J. J., Kelvin, D. J. (1993) Identification of RANTES receptors on human monocytic cells: competition for binding and desensitization by homologous chemotactic cytokines. J. Exp. Med. 177, 699-705.
    • (1993) J. Exp. Med. , vol.177 , pp. 699-705
    • Wang, J.M.1    MicVicar, D.W.2    Oppenheim, J.J.3    Kelvin, D.J.4
  • 26
    • 0032568918 scopus 로고    scopus 로고
    • Spontaneous and ligand induced trafficking of CXC-chemokine receptor 4
    • in press
    • Tarasova, N. I., Stauber, R. H., Michejda, C. J. (1998) Spontaneous and ligand induced trafficking of CXC-chemokine receptor 4. J. Biol. Chem. in press.
    • (1998) J. Biol. Chem.
    • Tarasova, N.I.1    Stauber, R.H.2    Michejda, C.J.3
  • 27
    • 0025193280 scopus 로고
    • Prototype of a new genereation of antitumor compounds
    • La Rocca, R. V. Stein, C. A., Myers, C. E. (1990) Prototype of a new genereation of antitumor compounds. Cancer Cells 2, 106-115.
    • (1990) Cancer Cells , vol.2 , pp. 106-115
    • La Rocca, R.V.1    Stein, C.A.2    Myers, C.E.3
  • 28
    • 0030749666 scopus 로고    scopus 로고
    • HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: Independence from G protein signaling and importance of coreceptor downmodulation
    • Alkhatib, G. L., Massimo, L., Kennedy, P. E., Murphy, P. M., Berger, E. A. (1997) HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: independence from G protein signaling and importance of coreceptor downmodulation. Virology 234, 340-348.
    • (1997) Virology , vol.234 , pp. 340-348
    • Alkhatib, G.L.1    Massimo, L.2    Kennedy, P.E.3    Murphy, P.M.4    Berger, E.A.5
  • 29
    • 0028429960 scopus 로고
    • Differential binding of chemokines to gylcosaminoglycan subpopulations
    • Witt, D. P., Lander, A. D. (1994) Differential binding of chemokines to gylcosaminoglycan subpopulations. Curr. Biol. 4, 394-400.
    • (1994) Curr. Biol. , vol.4 , pp. 394-400
    • Witt, D.P.1    Lander, A.D.2
  • 31
    • 0030447722 scopus 로고    scopus 로고
    • Multiple extracellular elements of CCR5 and HIV-1 entry: Dissociation from response to chemokines
    • Atchison, R. E., Gosling, J., Monteclaro, F. S., Franci, C., Digilio, L., Charo, I. F., Goldsmith, M. A. (1996) Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines. Science 274, 1924-1926.
    • (1996) Science , vol.274 , pp. 1924-1926
    • Atchison, R.E.1    Gosling, J.2    Monteclaro, F.S.3    Franci, C.4    Digilio, L.5    Charo, I.F.6    Goldsmith, M.A.7
  • 32
    • 0030812844 scopus 로고    scopus 로고
    • Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses
    • Kuhmann, S. E., Platt, E. J., Kozak, S. L., Kabat, D. (1997) Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses. J. Virol. 71, 8642-8656.
    • (1997) J. Virol. , vol.71 , pp. 8642-8656
    • Kuhmann, S.E.1    Platt, E.J.2    Kozak, S.L.3    Kabat, D.4
  • 33
    • 0030745286 scopus 로고    scopus 로고
    • HIV coreceptor downregulation as antiviral principal: SDF-1α-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication
    • Amara, A., Gall, S. L., Schwartz, O., Salamero, J., Montes, M., Loetscher, P., Baggiolini, M, Virelizier, J-L., Arenzana-Seisdedos, F. (1997) HIV coreceptor downregulation as antiviral principal: SDF-1α-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J. Exp. Med. 186, 139-146.
    • (1997) J. Exp. Med. , vol.186 , pp. 139-146
    • Amara, A.1    Gall, S.L.2    Schwartz, O.3    Salamero, J.4    Montes, M.5    Loetscher, P.6    Baggiolini, M.7    Virelizier, J.-L.8    Arenzana-Seisdedos, F.9


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