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Volumn 35, Issue 1, 1999, Pages 41-60

Mechanistic studies of molecular transdermal transport due to skin electroporation

Author keywords

Electroporation; Heat effect; Lipid; Multilamellar system; Phase transition; Stratum corneum; Transdermal transport

Indexed keywords

BIOELECTRIC PHENOMENA; MICROSTRUCTURE; MOLECULAR DYNAMICS; PHASE TRANSITIONS; SKIN;

EID: 0033521683     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(98)00062-3     Document Type: Article
Times cited : (58)

References (135)
  • 1
    • 0029041507 scopus 로고
    • Iontophoresis: Applications in transdermal medication delivery
    • Costello C.T., Jeske A.H. Iontophoresis: applications in transdermal medication delivery. Phys. Ther. 75:1995;554-563.
    • (1995) Phys. Ther. , vol.75 , pp. 554-563
    • Costello, C.T.1    Jeske, A.H.2
  • 3
    • 0027981088 scopus 로고
    • Iontophoresis of a model peptide across human skin in vitro: Effects of iontophoresis protocol, pH, and ionic strength on peptide flux and skin impedance
    • Craane van Hinsberg W.H.M., Bax L., Flinterman N.H., Verhoef J.C., Junginger H.E., Bodde H.E. Iontophoresis of a model peptide across human skin in vitro: Effects of iontophoresis protocol, pH, and ionic strength on peptide flux and skin impedance. Pharm. Res. 11:1994;1296-1300.
    • (1994) Pharm. Res. , vol.11 , pp. 1296-1300
    • Craane Van Hinsberg, W.H.M.1    Bax, L.2    Flinterman, N.H.3    Verhoef, J.C.4    Junginger, H.E.5    Bodde, H.E.6
  • 4
    • 0029552142 scopus 로고
    • Theoretical model of iontophoresis utilized in transdermal drug delivery
    • Ferry L.L. Theoretical model of iontophoresis utilized in transdermal drug delivery. Pharm. Acta Helv. 70:1995;279-287.
    • (1995) Pharm. Acta Helv. , vol.70 , pp. 279-287
    • Ferry, L.L.1
  • 5
  • 7
    • 0030017432 scopus 로고    scopus 로고
    • Recent developments in topical and transdermal delivery
    • Hadgraft J. Recent developments in topical and transdermal delivery. Eur. J. Drug Metab. Pharmacokinet. 21:1996;165-173.
    • (1996) Eur. J. Drug Metab. Pharmacokinet. , vol.21 , pp. 165-173
    • Hadgraft, J.1
  • 8
    • 0028029315 scopus 로고
    • Enhancement of iontophoretic permeation of insulin across human cadaver skin
    • Rao V.U., Misra A.N. Enhancement of iontophoretic permeation of insulin across human cadaver skin. Pharmazie. 49:1994;538-539.
    • (1994) Pharmazie , vol.49 , pp. 538-539
    • Rao, V.U.1    Misra, A.N.2
  • 9
    • 0023854208 scopus 로고
    • Characterization of the pore transport properties and tissue alteration of excised human skin during iontophoresis
    • R.R. Burnette, B. Ongpipattanakul, Characterization of the pore transport properties and tissue alteration of excised human skin during iontophoresis, J. Pharm. Sci. (1988) 132-137.
    • (1988) J. Pharm. Sci. , pp. 132-137
    • Burnette, R.R.1    Ongpipattanakul, B.2
  • 10
    • 0028789537 scopus 로고
    • Role of appendages in skin resistance and iontophoretic peptide flux: Human versus snake skin
    • Craane van Hinsberg W.H.M., Verhoef J.C., Bax L.J., Junginger H.E., Bodde H.E. Role of appendages in skin resistance and iontophoretic peptide flux: human versus snake skin. Pharm. Res. 12:1995;1506-1512.
    • (1995) Pharm. Res. , vol.12 , pp. 1506-1512
    • Craane Van Hinsberg, W.H.M.1    Verhoef, J.C.2    Bax, L.J.3    Junginger, H.E.4    Bodde, H.E.5
  • 11
    • 0026928544 scopus 로고
    • What are the pathways of iontophoretic current flow through mammalian skin
    • C. Cullander, What are the pathways of iontophoretic current flow through mammalian skin, Adv. Drug Deliv. Rev. (1992) 119-135.
    • (1992) Adv. Drug Deliv. Rev. , pp. 119-135
    • Cullander, C.1
  • 12
    • 0025865078 scopus 로고
    • Sites of iontophoretic current flow into the skin: Identification and characterization with the vibrating probe electrode
    • Cullander C., Guy R.H. Sites of iontophoretic current flow into the skin: identification and characterization with the vibrating probe electrode. J. Invest. Dermatol. 97:1991;55-64.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 55-64
    • Cullander, C.1    Guy, R.H.2
  • 13
    • 0021236368 scopus 로고
    • Pathways of ionic flow through human skin in vivo
    • S. Grimnes, Pathways of ionic flow through human skin in vivo, Acta Derm.-Venereol. (Stockholm) (1984) 93-98.
    • (1984) Acta Derm.-Venereol. (Stockholm) , pp. 93-98
    • Grimnes, S.1
  • 14
    • 0028347849 scopus 로고
    • Identification of the pathway of iontophoretic drug delivery: Light and ultrastructural studies using mercuric chloride in pigs
    • Monteiro Riviere N.A., Inman A.O., Riviere J.E. Identification of the pathway of iontophoretic drug delivery: light and ultrastructural studies using mercuric chloride in pigs. Pharm. Res. 11:1994;251-256.
    • (1994) Pharm. Res. , vol.11 , pp. 251-256
    • Monteiro Riviere, N.A.1    Inman, A.O.2    Riviere, J.E.3
  • 16
    • 0027131181 scopus 로고
    • Transport of ionic species in skin: Contribution of pores to the overall skin conductance
    • Scott E.R., Laplaza A.I., White H.S., Phipps J.B. Transport of ionic species in skin: contribution of pores to the overall skin conductance. Pharm. Res. 10:1993;1699-1709.
    • (1993) Pharm. Res. , vol.10 , pp. 1699-1709
    • Scott, E.R.1    Laplaza, A.I.2    White, H.S.3    Phipps, J.B.4
  • 17
    • 0026896473 scopus 로고
    • Direct imaging of ionic pathways in stratum corneum using scanning electrochemical microscopy
    • E.R. Scott, H.S. White, J.B. Phipps, Direct imaging of ionic pathways in stratum corneum using scanning electrochemical microscopy, Solid State Ionics (1992) 176-183.
    • (1992) Solid State Ionics , pp. 176-183
    • Scott, E.R.1    White, H.S.2    Phipps, J.B.3
  • 18
    • 0029071855 scopus 로고
    • The use of ultrasound as an enhancer for transcutaneous drug delivery: Phonophoresis
    • Byl N.N. The use of ultrasound as an enhancer for transcutaneous drug delivery: phonophoresis. Phys. Ther. 75:1995;539-553.
    • (1995) Phys. Ther. , vol.75 , pp. 539-553
    • Byl, N.N.1
  • 19
    • 0029809525 scopus 로고    scopus 로고
    • Difference in the enhancing effects of ultrasound on the skin permeation of polar and non-polar drugs
    • Ueda H., Ogihara M., Sugibayashi K., Morimoto Y. Difference in the enhancing effects of ultrasound on the skin permeation of polar and non-polar drugs. Chem. Pharm. Bull. Tokyo. 44:1996;1973-1976.
    • (1996) Chem. Pharm. Bull. Tokyo , vol.44 , pp. 1973-1976
    • Ueda, H.1    Ogihara, M.2    Sugibayashi, K.3    Morimoto, Y.4
  • 20
    • 0029125922 scopus 로고
    • Ultrasound-mediated transdermal protein delivery
    • Mitragotri S., Blankschtein D., Langer R. Ultrasound-mediated transdermal protein delivery. Science. 269:1995;850-853.
    • (1995) Science , vol.269 , pp. 850-853
    • Mitragotri, S.1    Blankschtein, D.2    Langer, R.3
  • 21
    • 0026457610 scopus 로고
    • External control of drug release and penetration. VI. Enhancing effect of ultrasound on the transdermal absorption of indomethacin from an ointment in rats
    • Miyazaki S., Mizuoka H., Kohata Y., Takada M. External control of drug release and penetration. VI. Enhancing effect of ultrasound on the transdermal absorption of indomethacin from an ointment in rats. Chem. Pharm. Bull. Tokyo. 40:1992;2826-2830.
    • (1992) Chem. Pharm. Bull. Tokyo , vol.40 , pp. 2826-2830
    • Miyazaki, S.1    Mizuoka, H.2    Kohata, Y.3    Takada, M.4
  • 22
    • 0026721597 scopus 로고
    • Transdermal delivery of insulin to alloxan-diabetic rabbits by ultrasound exposure
    • Tachibana K. Transdermal delivery of insulin to alloxan-diabetic rabbits by ultrasound exposure. Pharm. Res. 9:1992;952-954.
    • (1992) Pharm. Res. , vol.9 , pp. 952-954
    • Tachibana, K.1
  • 23
    • 0026739410 scopus 로고
    • Sonophoresis. II. Examination of the mechanism(s) of ultrasound-enhanced transdermal drug delivery
    • Bommannan D.B., Menon G.K., Okuyama H., Elias P.M., Guy R.H. Sonophoresis. II. Examination of the mechanism(s) of ultrasound-enhanced transdermal drug delivery. Pharm. Res. 9:1992;1043-1047.
    • (1992) Pharm. Res. , vol.9 , pp. 1043-1047
    • Bommannan, D.B.1    Menon, G.K.2    Okuyama, H.3    Elias, P.M.4    Guy, R.H.5
  • 24
    • 0026513267 scopus 로고
    • Sonophoresis. I. The use of high-frequency ultrasound to enhance transdermal drug delivery
    • Bommannan D.B., Okuyama H., Stauffer P., Guy R.H. Sonophoresis. I. The use of high-frequency ultrasound to enhance transdermal drug delivery. Pharm. Res. 9:1992;559-564.
    • (1992) Pharm. Res. , vol.9 , pp. 559-564
    • Bommannan, D.B.1    Okuyama, H.2    Stauffer, P.3    Guy, R.H.4
  • 26
    • 0027379355 scopus 로고
    • Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery
    • Prausnitz M.R., Bose V.G., Langer R., Weaver J.C. Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery. PNAS. 90:1993;10504-10508.
    • (1993) PNAS , vol.90 , pp. 10504-10508
    • Prausnitz, M.R.1    Bose, V.G.2    Langer, R.3    Weaver, J.C.4
  • 28
    • 0028020044 scopus 로고
    • Effect of electroporation on transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH) in vitro
    • Bommannan D.B., Tamada J.A., Leung L., Potts R.O. Effect of electroporation on transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH) in vitro. Pharm. Res. 11:1994;1809-1814.
    • (1994) Pharm. Res. , vol.11 , pp. 1809-1814
    • Bommannan, D.B.1    Tamada, J.A.2    Leung, L.3    Potts, R.O.4
  • 29
    • 0002116818 scopus 로고    scopus 로고
    • Electroporation of human skin: simultaneous measurement of changes in the transport of two fluorescent molecules and in the passive electrical properties
    • U. Pliquett and J.C. Weaver, Electroporation of human skin: simultaneous measurement of changes in the transport of two fluorescent molecules and in the passive electrical properties, Bioelectrochem. Bioenerg. (1996) 1-12.
    • (1996) Bioelectrochem. Bioenerg. , pp. 1-12
    • Pliquett, U.1    Weaver, J.C.2
  • 30
    • 0030026418 scopus 로고    scopus 로고
    • Transport of a charged molecule across the human epidermis due to electroporation
    • U. Pliquett, J.C. Weaver, Transport of a charged molecule across the human epidermis due to electroporation, J. Control. Release (1996) 1-10.
    • (1996) J. Control. Release , pp. 1-10
    • Pliquett, U.1    Weaver, J.C.2
  • 31
    • 0027944964 scopus 로고
    • Rapid temporal control of transdermal drug delivery by electroporation
    • Prausnitz M.R., Pliquett U., Langer R., Weaver J.C. Rapid temporal control of transdermal drug delivery by electroporation. Pharm. Res. 11:1994;1834-1837.
    • (1994) Pharm. Res. , vol.11 , pp. 1834-1837
    • Prausnitz, M.R.1    Pliquett, U.2    Langer, R.3    Weaver, J.C.4
  • 34
    • 0030000445 scopus 로고    scopus 로고
    • Transdermal delivery of fentanyl by electroporation. I. Influence of electrical factors
    • Vanbever R., LeBoulenge E., Preat V. Transdermal delivery of fentanyl by electroporation. I. Influence of electrical factors. Pharm. Res. 13:1996;559-565.
    • (1996) Pharm. Res. , vol.13 , pp. 559-565
    • Vanbever, R.1    Leboulenge, E.2    Preat, V.3
  • 35
    • 0028130432 scopus 로고
    • Transdermal delivery of metoprolol by electroporation
    • Vanbever R., Lecouturier N., Preat V. Transdermal delivery of metoprolol by electroporation. Pharm. Res. 11:1994;1657-1662.
    • (1994) Pharm. Res. , vol.11 , pp. 1657-1662
    • Vanbever, R.1    Lecouturier, N.2    Preat, V.3
  • 36
    • 0027474245 scopus 로고
    • Electroporation: A general phenomenon for manipulating cells and tissue
    • J.C. Weaver, Electroporation: A general phenomenon for manipulating cells and tissue, J. Cell. Biochem. (1993) 426-435.
    • (1993) J. Cell. Biochem. , pp. 426-435
    • Weaver, J.C.1
  • 39
    • 0028950699 scopus 로고
    • Mechanism of electroinduced ionic species transport through a multilamellar lipid system
    • Chizmadzhev Y.A., Zarnitsin V.G., Weaver J.C., Potts R.O. Mechanism of electroinduced ionic species transport through a multilamellar lipid system. Biophys. J. 68:1995;749-765.
    • (1995) Biophys. J. , vol.68 , pp. 749-765
    • Chizmadzhev, Y.A.1    Zarnitsin, V.G.2    Weaver, J.C.3    Potts, R.O.4
  • 41
    • 0345006069 scopus 로고    scopus 로고
    • Transdermal delivery of fentanyl by electroporation II. Mechanisms involved in drug transport
    • R. Vanbever, N. de Morre, V. Preat, Transdermal delivery of fentanyl by electroporation II. Mechanisms involved in drug transport, Pharm. Res. (1997).
    • (1997) Pharm. Res.
    • Vanbever, R.1    De Morre, N.2    Preat, V.3
  • 42
    • 0019820246 scopus 로고
    • Percutaneous transport in relation to stratum corneum structure and lipid composition
    • Elias P.M., Cooper E.R., Korc A., Brown B.E. Percutaneous transport in relation to stratum corneum structure and lipid composition. J. Invest. Derm. 76:1981;297-301.
    • (1981) J. Invest. Derm. , vol.76 , pp. 297-301
    • Elias, P.M.1    Cooper, E.R.2    Korc, A.3    Brown, B.E.4
  • 44
    • 0029987830 scopus 로고    scopus 로고
    • Structure of stratum corneum lipids characterized by FT-Raman spectroscopy and DSC: I. Ceramides
    • Wegener M., Neubert R., Rettig W., Wartewig S. Structure of stratum corneum lipids characterized by FT-Raman spectroscopy and DSC: I. Ceramides. Int. J. Pharm. 128:1996;203-213.
    • (1996) Int. J. Pharm. , vol.128 , pp. 203-213
    • Wegener, M.1    Neubert, R.2    Rettig, W.3    Wartewig, S.4
  • 45
    • 0026265525 scopus 로고
    • Structural and lipid biochemical correlates of the epidermal permeability barrier
    • P.M. Elias, G.K. Menon, Structural and lipid biochemical correlates of the epidermal permeability barrier, J. Adv. Lipid Res. (1991) 1-26.
    • (1991) J. Adv. Lipid Res. , pp. 1-26
    • Elias, P.M.1    Menon, G.K.2
  • 46
    • 0019820246 scopus 로고
    • Percutaneous transport in relation to stratum corneum structure and lipid composition
    • P.M. Elias, E.R. Cooper, A. Korc, B.E. Brown, Percutaneous transport in relation to stratum corneum structure and lipid composition, J. Invest. Derm. (1981) 297-301.
    • (1981) J. Invest. Derm. , pp. 297-301
    • Elias, P.M.1    Cooper, E.R.2    Korc, A.3    Brown, B.E.4
  • 49
    • 0030051547 scopus 로고    scopus 로고
    • A critical comparison of methods to quantify stratum corneum removed by tape stripping
    • Marttin E., Neelissen Subnel M.T.A., de Haan F.H.N., Bodde H.E. A critical comparison of methods to quantify stratum corneum removed by tape stripping. Skin Pharmacol. 9:1996;69-77.
    • (1996) Skin Pharmacol. , vol.9 , pp. 69-77
    • Marttin, E.1    Neelissen Subnel, M.T.A.2    De Haan, F.H.N.3    Bodde, H.E.4
  • 50
    • 0029764146 scopus 로고    scopus 로고
    • Stratum corneum lipids of human epidermal keratinocyte air-liquid cultures: Implications for barrier function
    • Kennedy A.H., Golden G.M., Gay C.L., Guy R.H., Francoeur M.L., Mak V.H.W. Stratum corneum lipids of human epidermal keratinocyte air-liquid cultures: Implications for barrier function. Pharm. Res. 13:1996;1162-1167.
    • (1996) Pharm. Res. , vol.13 , pp. 1162-1167
    • Kennedy, A.H.1    Golden, G.M.2    Gay, C.L.3    Guy, R.H.4    Francoeur, M.L.5    Mak, V.H.W.6
  • 51
    • 0030003515 scopus 로고    scopus 로고
    • Topical iontophoretic drug delivery: Pathways, principles, factors, and skin irritation
    • Singh J., Bhatia K.S. Topical iontophoretic drug delivery: pathways, principles, factors, and skin irritation. Med. Res. Rev. 16:1996;285-296.
    • (1996) Med. Res. Rev. , vol.16 , pp. 285-296
    • Singh, J.1    Bhatia, K.S.2
  • 52
    • 0029073739 scopus 로고
    • Importance of dermal blood supply and epidermis on the transdermal iontophoretic delivery of monovalent cations
    • Cross S.E., Roberts M.S. Importance of dermal blood supply and epidermis on the transdermal iontophoretic delivery of monovalent cations. J. Pharm. Sci. 84:1995;584-592.
    • (1995) J. Pharm. Sci. , vol.84 , pp. 584-592
    • Cross, S.E.1    Roberts, M.S.2
  • 53
    • 0027227505 scopus 로고
    • Two-layer membrane model for iontophoretic drug transport through excised rat skin
    • Inada H., Mizuguchi K., Katayama K., Kakemi M., Koizumi T. Two-layer membrane model for iontophoretic drug transport through excised rat skin. Biol. Pharm. Bull. 16:1993;589-593.
    • (1993) Biol. Pharm. Bull. , vol.16 , pp. 589-593
    • Inada, H.1    Mizuguchi, K.2    Katayama, K.3    Kakemi, M.4    Koizumi, T.5
  • 54
    • 0026446157 scopus 로고
    • Lamellar structures formed by stratum corneum lipids in vitro: A deuterium nuclear magnetic resonance (NMR) study
    • Abraham W., Downing D.T. Lamellar structures formed by stratum corneum lipids in vitro: A deuterium nuclear magnetic resonance (NMR) study. Pharm. Res. 9:1992;1415-1421.
    • (1992) Pharm. Res. , vol.9 , pp. 1415-1421
    • Abraham, W.1    Downing, D.T.2
  • 55
    • 0025821769 scopus 로고
    • Epidermal barrier function: intercellular lamellar lipid structures, origin, composition and metabolism
    • P.M. Elias, Epidermal barrier function: intercellular lamellar lipid structures, origin, composition and metabolism, J. Control. Release (1991) 199-208.
    • (1991) J. Control. Release , pp. 199-208
    • Elias, P.M.1
  • 56
    • 0029061075 scopus 로고
    • Interactions between liposomes and human stratum corneum in vitro: Freeze fracture electron microscopical visualization and small angle X-ray scattering studies
    • Hofland H.E.J., Bouwstra J., Bodde H.E., Spies F., Junginger H.E. Interactions between liposomes and human stratum corneum in vitro: Freeze fracture electron microscopical visualization and small angle X-ray scattering studies. Br. J. Dermatol. 132:1995;853-856.
    • (1995) Br. J. Dermatol. , vol.132 , pp. 853-856
    • Hofland, H.E.J.1    Bouwstra, J.2    Bodde, H.E.3    Spies, F.4    Junginger, H.E.5
  • 57
    • 0027285001 scopus 로고
    • Development of a model membrane system using stratum corneum lipids for estimation of drug skin permeability
    • Matsuzaki K., Imaoka T., Asano M., Miyajima K. Development of a model membrane system using stratum corneum lipids for estimation of drug skin permeability. Chem. Pharm. Bull. Tokyo. 41:1993;575-579.
    • (1993) Chem. Pharm. Bull. Tokyo , vol.41 , pp. 575-579
    • Matsuzaki, K.1    Imaoka, T.2    Asano, M.3    Miyajima, K.4
  • 58
    • 0029917046 scopus 로고    scopus 로고
    • A lamellar matrix model for stratum corneum intercellular lipids. II. Effect of geometry of the stratum corneum on permeation of model drugs 5-fluorouracil and oestradiol
    • Moghimi H.R., Williams A.C., Barry B.W. A lamellar matrix model for stratum corneum intercellular lipids. II. Effect of geometry of the stratum corneum on permeation of model drugs 5-fluorouracil and oestradiol. Int. J. Pharm. 131:1996;117-129.
    • (1996) Int. J. Pharm. , vol.131 , pp. 117-129
    • Moghimi, H.R.1    Williams, A.C.2    Barry, B.W.3
  • 59
    • 0029913714 scopus 로고    scopus 로고
    • A lamellar matrix model for stratum corneum intercellular lipids. I. Characterisation and comparison with stratum corneum intercellular structure
    • Moghimi H.R., Williams A.C., Barry B.W. A lamellar matrix model for stratum corneum intercellular lipids. I. Characterisation and comparison with stratum corneum intercellular structure. Int. J. Pharm. 131:1996;103-115.
    • (1996) Int. J. Pharm. , vol.131 , pp. 103-115
    • Moghimi, H.R.1    Williams, A.C.2    Barry, B.W.3
  • 60
    • 0017279342 scopus 로고
    • A minimum-surface mechanism to account for the organization of cells into columns in the mammalian epidermis
    • Menton D.N. A minimum-surface mechanism to account for the organization of cells into columns in the mammalian epidermis. Am. J. Anat. 145:1976;1-22.
    • (1976) Am. J. Anat. , vol.145 , pp. 1-22
    • Menton, D.N.1
  • 61
    • 0024262093 scopus 로고
    • Structure and function of the stratum corneum permeability barrier
    • P.M. Elias, Structure and function of the stratum corneum permeability barrier, Drug Dev. Res. (1988) 97-105.
    • (1988) Drug Dev. Res. , pp. 97-105
    • Elias, P.M.1
  • 62
    • 0015067051 scopus 로고
    • Structure and organization of mamallies stratum corneum
    • Menton D.N., Eisen A.Z. Structure and organization of mamallies stratum corneum. J. Ultrastruct. Res. 35:1971;247-264.
    • (1971) J. Ultrastruct. Res. , vol.35 , pp. 247-264
    • Menton, D.N.1    Eisen, A.Z.2
  • 64
    • 0028816731 scopus 로고
    • Molecular properties of a stratum corneum model lipid system: Large unilamellar vesicles
    • Hatfield R.M., Fung L.W. Molecular properties of a stratum corneum model lipid system: large unilamellar vesicles. Biophys. J. 68:1995;196-207.
    • (1995) Biophys. J. , vol.68 , pp. 196-207
    • Hatfield, R.M.1    Fung, L.W.2
  • 65
    • 0026279967 scopus 로고
    • The biochemistry and function of stratum corneum lipids
    • Schurer N.Y., Elias P.M. The biochemistry and function of stratum corneum lipids. Adv. Lipid Res. 24:1991;27-56.
    • (1991) Adv. Lipid Res. , vol.24 , pp. 27-56
    • Schurer, N.Y.1    Elias, P.M.2
  • 66
    • 0025828769 scopus 로고    scopus 로고
    • Visualization of in vitro percutaneous penetration of mercuric chloride transport through intercellular space versus cellular uptake through desmosomes
    • H.E. Bodde, I. van den Brink, H.K. Koerten, F.H.N. de Haan, Visualization of in vitro percutaneous penetration of mercuric chloride transport through intercellular space versus cellular uptake through desmosomes, J. Control. Release (1997) 227-236.
    • (1997) J. Control. Release , pp. 227-236
    • Bodde, H.E.1    Van Den Brink, I.2    Koerten, H.K.3    De Haan, F.H.N.4
  • 68
    • 0029014503 scopus 로고
    • Visualization of diffusion pathways across the stratum corneum of native and in vitro-reconstructed epidermis by confocal laser scanning microscopy
    • Simonetti O., Hoogstraate A.J., Bialik W., Kempenaar J., Schrijvers A.H.G.J., Bodde H.E., Ponec M. Visualization of diffusion pathways across the stratum corneum of native and in vitro-reconstructed epidermis by confocal laser scanning microscopy. Arch. Dermatol. Res. 287:1995;465-473.
    • (1995) Arch. Dermatol. Res. , vol.287 , pp. 465-473
    • Simonetti, O.1    Hoogstraate, A.J.2    Bialik, W.3    Kempenaar, J.4    Schrijvers, A.H.G.J.5    Bodde, H.E.6    Ponec, M.7
  • 72
    • 0026458067 scopus 로고
    • The stratum corneum lipid thermotrophic phase behavior
    • Krill S.L., Knotson K., Higuchi W.I. The stratum corneum lipid thermotrophic phase behavior. BBA. 1112:1992;281-286.
    • (1992) BBA , vol.1112 , pp. 281-286
    • Krill, S.L.1    Knotson, K.2    Higuchi, W.I.3
  • 76
    • 0028361024 scopus 로고
    • Theory of electroporation for a planar bilayer membrane: predictions of the fractional aqueous area, change in capacitance and pore-pore separation
    • S.A. Freeman, M.A. Wang, J.C. Weaver, Theory of electroporation for a planar bilayer membrane: predictions of the fractional aqueous area, change in capacitance and pore-pore separation, Biophys. J. (1994) 42-56.
    • (1994) Biophys. J. , pp. 42-56
    • Freeman, S.A.1    Wang, M.A.2    Weaver, J.C.3
  • 78
    • 0030018318 scopus 로고    scopus 로고
    • Human stratum corneum lipids have a distorted orthorhombic packing at the surface of cohesive failure
    • Chen Y.L., Wiedmann T.S. Human stratum corneum lipids have a distorted orthorhombic packing at the surface of cohesive failure. J. Invest. Dermatol. 107:1996;15-19.
    • (1996) J. Invest. Dermatol. , vol.107 , pp. 15-19
    • Chen, Y.L.1    Wiedmann, T.S.2
  • 79
    • 0029565731 scopus 로고
    • pH-Dependence of phase transition of the lipid bilayer of liposomes of stratum corneum lipids
    • S. Kitagawa, N. Yokochi, N. Murooka, pH-Dependence of phase transition of the lipid bilayer of liposomes of stratum corneum lipids, Int. J. Pharm. (1995) 49-56.
    • (1995) Int. J. Pharm. , pp. 49-56
    • Kitagawa, S.1    Yokochi, N.2    Murooka, N.3
  • 80
    • 0027412202 scopus 로고
    • Electrochemical characterization of human skin by impedance spectroscopy: The effect of penetration enhancers
    • Kontturi K., Murtomaki L., Hirvonen J., Paronen P., Urtti A. Electrochemical characterization of human skin by impedance spectroscopy: the effect of penetration enhancers. Pharm. Res. 10:1993;381-385.
    • (1993) Pharm. Res. , vol.10 , pp. 381-385
    • Kontturi, K.1    Murtomaki, L.2    Hirvonen, J.3    Paronen, P.4    Urtti, A.5
  • 81
    • 0010440778 scopus 로고
    • Electrical properties of skin
    • in: H.R. Elden (Ed.) Wiley, New York
    • Edelberg, Electrical properties of skin, in: H.R. Elden (Ed.), Biophysical Properties of the Skin, Wiley, New York, 1971, pp. 513-550.
    • (1971) Biophysical Properties of the Skin , pp. 513-550
    • Edelberg1
  • 82
    • 0028253395 scopus 로고
    • Measurement and analysis of skin electrical impedance
    • Yamamoto Y. Measurement and analysis of skin electrical impedance. Acta Derm.-Venereol. (Stockholm). 185:1994;34-38.
    • (1994) Acta Derm.-Venereol. (Stockholm) , vol.185 , pp. 34-38
    • Yamamoto, Y.1
  • 83
    • 0030031759 scopus 로고    scopus 로고
    • Passive electrical properties of human stratum corneum in vitro depending on time after separation
    • Pliquett F., Pliquett U. Passive electrical properties of human stratum corneum in vitro depending on time after separation. Biophys. Chem. 58:1996;205-210.
    • (1996) Biophys. Chem. , vol.58 , pp. 205-210
    • Pliquett, F.1    Pliquett, U.2
  • 84
    • 0028849109 scopus 로고
    • Changes in the passive electrical properties of human stratum corneum due to electroporation
    • Pliquett U., Langer R., Weaver J.C. Changes in the passive electrical properties of human stratum corneum due to electroporation. BBA. 1239:1995;111-121.
    • (1995) BBA , vol.1239 , pp. 111-121
    • Pliquett, U.1    Langer, R.2    Weaver, J.C.3
  • 86
    • 0024572263 scopus 로고
    • Dielectric properties of tissues and biological materials: A critical revue
    • Foster K.R., Schwan H.P. Dielectric properties of tissues and biological materials: A critical revue. CRC Crit. Rev. Biomed. Eng. 17:1989;25-104.
    • (1989) CRC Crit. Rev. Biomed. Eng. , vol.17 , pp. 25-104
    • Foster, K.R.1    Schwan, H.P.2
  • 87
    • 0020750771 scopus 로고
    • Dielectric breakdown of human skin in vivo
    • S. Grimnes, Dielectric breakdown of human skin in vivo, Med. Biol. Eng. Comput. (1983) 379-381.
    • (1983) Med. Biol. Eng. Comput. , pp. 379-381
    • Grimnes, S.1
  • 89
    • 0030071315 scopus 로고    scopus 로고
    • Imaging of fluorescent molecule and small ion transport through human stratum corneum during high-voltage pulsing: Localized transport regions are involved
    • Pliquett U., Zewert T.E., Chen T., Langer R., Weaver J.C. Imaging of fluorescent molecule and small ion transport through human stratum corneum during high-voltage pulsing: Localized transport regions are involved. Biophys. Chem. 58:1996;185-204.
    • (1996) Biophys. Chem. , vol.58 , pp. 185-204
    • Pliquett, U.1    Zewert, T.E.2    Chen, T.3    Langer, R.4    Weaver, J.C.5
  • 94
    • 84987398217 scopus 로고
    • Upper and lower limits of human skin electrical resistance in iontophoresis
    • S.M. Dinh, C.W. Luo, B. Berner, Upper and lower limits of human skin electrical resistance in iontophoresis, AIChE J. (1993) 2011-1018.
    • (1993) AIChE J. , pp. 2011-1018
    • Dinh, S.M.1    Luo, C.W.2    Berner, B.3
  • 95
    • 0028352235 scopus 로고
    • Studies on the effects of applied voltage and duration on human epidermal membrane alteration/recovery and the resultant effects upon iontophoresis
    • Inada H., Ghanem A.H., Higuchi W.I. Studies on the effects of applied voltage and duration on human epidermal membrane alteration/recovery and the resultant effects upon iontophoresis. Pharm. Res. 11:1994;687-697.
    • (1994) Pharm. Res. , vol.11 , pp. 687-697
    • Inada, H.1    Ghanem, A.H.2    Higuchi, W.I.3
  • 96
    • 0029904252 scopus 로고    scopus 로고
    • The effect of iontophoresis on skin barrier integrity: Non-invasive evaluation by impedance spectroscopy and transepidermal water loss
    • Kalia Y.N., Nonato L.B., Guy R.H. The effect of iontophoresis on skin barrier integrity: non-invasive evaluation by impedance spectroscopy and transepidermal water loss. Pharm. Res. 13:1996;957-960.
    • (1996) Pharm. Res. , vol.13 , pp. 957-960
    • Kalia, Y.N.1    Nonato, L.B.2    Guy, R.H.3
  • 97
    • 0027486456 scopus 로고
    • Effect of current, ionic strength and temperature on the electrical properties of skin
    • Oh S.Y., Leung L., Bommannan D.B., Guy R.H., Potts R.O. Effect of current, ionic strength and temperature on the electrical properties of skin. J. Control. Release. 27:1993;115-125.
    • (1993) J. Control. Release , vol.27 , pp. 115-125
    • Oh, S.Y.1    Leung, L.2    Bommannan, D.B.3    Guy, R.H.4    Potts, R.O.5
  • 98
    • 0026453431 scopus 로고
    • Skin alteration and convective solvent flow effects during iontophoresis: II. Monovalent anion and cation transport across human skin
    • Sims S.M., Higuchi W.I., Srinivasan V. Skin alteration and convective solvent flow effects during iontophoresis: II. Monovalent anion and cation transport across human skin. Pharm. Res. 9:1992;1402-1409.
    • (1992) Pharm. Res. , vol.9 , pp. 1402-1409
    • Sims, S.M.1    Higuchi, W.I.2    Srinivasan, V.3
  • 99
    • 0342997686 scopus 로고    scopus 로고
    • Perturbation of human stratum corneum: electric field application vs. heating
    • in: J.R. Riu et al. (Eds.) Barcelona, Spain, Publications Office of UPC, Barcelona
    • U. Pliquett, C. Gusbeth, F. Pliquett, Perturbation of human stratum corneum: electric field application vs. heating, in: J.R. Riu et al. (Eds.), Proceeding of the X. International Conference on Electrical Bio-Impedance, Barcelona, Spain, Publications Office of UPC, Barcelona, 1998. pp. 277-280.
    • (1998) Proceeding of the X. International Conference on Electrical Bio-Impedance , pp. 277-280
    • Pliquett, U.1    Gusbeth, C.2    Pliquett, F.3
  • 100
    • 0029922803 scopus 로고    scopus 로고
    • Do high voltage pulses cause changes in skin structure?
    • M.R. Prausnitz, Do high voltage pulses cause changes in skin structure? J. Control. Release (1996) 1317.
    • (1996) J. Control. Release , pp. 1317
    • Prausnitz, M.R.1
  • 102
    • 0030457097 scopus 로고    scopus 로고
    • Imaging regions of transport across human stratum corneum during high voltage and low voltage exposures
    • M.R. Prausnitz, J.A. Gimm, R.H. Guy, R. Langer, J.C. Weaver, C. Cullander, Imaging regions of transport across human stratum corneum during high voltage and low voltage exposures, J. Pharm. Sci. (1996) 1363-1370.
    • (1996) J. Pharm. Sci. , pp. 1363-1370
    • Prausnitz, M.R.1    Gimm, J.A.2    Guy, R.H.3    Langer, R.4    Weaver, J.C.5    Cullander, C.6
  • 103
    • 0032215553 scopus 로고    scopus 로고
    • Local transport regions (LTRs) in human stratum corneum due to long and short high voltage pulses
    • in press
    • U. Pliquett, R. Vanbever, J.C. Weaver, Local transport regions (LTRs) in human stratum corneum due to long and short high voltage pulses, Bioelectrochem. Bioenerg., in press.
    • Bioelectrochem. Bioenerg.
    • Pliquett, U.1    Vanbever, R.2    Weaver, J.C.3
  • 105
    • 0025863145 scopus 로고
    • Stratum corneum lipids serve as a bound-water modulator
    • Imokawa G., Kuno H., Kawai M. Stratum corneum lipids serve as a bound-water modulator. J. Invest. Dermatol. 96:1991;845-851.
    • (1991) J. Invest. Dermatol. , vol.96 , pp. 845-851
    • Imokawa, G.1    Kuno, H.2    Kawai, M.3
  • 108
    • 0031401883 scopus 로고    scopus 로고
    • Electroperturbation of the human skin barrier in vitro (I): The influence of current density on the thermal behaviour of skin impedance
    • Craane van Hinsberg W.H.M., Verhoef J.C., Junginger H.E., Bodde H.E. Electroperturbation of the human skin barrier in vitro (I): The influence of current density on the thermal behaviour of skin impedance. Eur. J. Pharm. Biopharm. 43:1997;43-50.
    • (1997) Eur. J. Pharm. Biopharm. , vol.43 , pp. 43-50
    • Craane Van Hinsberg, W.H.M.1    Verhoef, J.C.2    Junginger, H.E.3    Bodde, H.E.4
  • 109
    • 0030248493 scopus 로고    scopus 로고
    • Non-invasive assessment of skin barrier integrity and skin irritation following iontophoretic current application in humans
    • van der Geest R., Elshove D.A.R., Danhof M., Lavrijesen A.P.M., Bodde H.E. Non-invasive assessment of skin barrier integrity and skin irritation following iontophoretic current application in humans. J. Control. Release. 41:1996;205-213.
    • (1996) J. Control. Release , vol.41 , pp. 205-213
    • Van Der Geest, R.1    Elshove, D.A.R.2    Danhof, M.3    Lavrijesen, A.P.M.4    Bodde, H.E.5
  • 111
    • 0027291215 scopus 로고
    • Convective solvent flow across the skin during iontophoresis
    • Kim A., Green P.G., Rao G., Guy R.H. Convective solvent flow across the skin during iontophoresis. Pharm. Res. 10:1993;1315-1320.
    • (1993) Pharm. Res. , vol.10 , pp. 1315-1320
    • Kim, A.1    Green, P.G.2    Rao, G.3    Guy, R.H.4
  • 112
    • 0028869479 scopus 로고
    • Direct imaging of molecular transport through skin
    • Scott E.R., Phipps J.B., White H.S. Direct imaging of molecular transport through skin. J. Invest. Dermatol. 104:1995;142-145.
    • (1995) J. Invest. Dermatol. , vol.104 , pp. 142-145
    • Scott, E.R.1    Phipps, J.B.2    White, H.S.3
  • 113
    • 0344575020 scopus 로고    scopus 로고
    • Temperature rising during tissue electroporation: theoretical modeling
    • submitted
    • G.T. Martin, U. Pliquett, J.C. Weaver, Temperature rising during tissue electroporation: theoretical modeling, J. Contr. Rel., submitted.
    • J. Contr. Rel.
    • Martin, G.T.1    Pliquett, U.2    Weaver, J.C.3
  • 115
    • 0344575018 scopus 로고    scopus 로고
    • Kinetics of temperature rise within the stratum corneum during electroporation and pulsed high voltage iontophoresis
    • submitted
    • U. Pliquett, G.T. Martin, J.C. Weaver, Kinetics of temperature rise within the stratum corneum during electroporation and pulsed high voltage iontophoresis, J. Contr. Rel., submitted.
    • J. Contr. Rel.
    • Pliquett, U.1    Martin, G.T.2    Weaver, J.C.3
  • 116
    • 0344575019 scopus 로고    scopus 로고
    • Perturbation of skin due to high voltage application: experimental approach
    • in press
    • U. Pliquett, C. Gusbeth, Perturbation of skin due to high voltage application: experimental approach, Pharm. Res., in press.
    • Pharm. Res.
    • Pliquett, U.1    Gusbeth, C.2
  • 117
    • 0027368424 scopus 로고
    • Barrier function parameters in various keratinization disorders: Transepidermal water loss vascular response to hexyl nicotinate
    • Lavrijesen A.P.M., Oestmann E., Hermans J., Bodde H.E., Vermeer B.J., Ponec M. Barrier function parameters in various keratinization disorders: Transepidermal water loss vascular response to hexyl nicotinate. Br. J. Dermatol. 129:1993;547-553.
    • (1993) Br. J. Dermatol. , vol.129 , pp. 547-553
    • Lavrijesen, A.P.M.1    Oestmann, E.2    Hermans, J.3    Bodde, H.E.4    Vermeer, B.J.5    Ponec, M.6
  • 118
    • 0029759449 scopus 로고    scopus 로고
    • The influence of an electric field on ion and water accessibility to stratum corneum lipid lamellae
    • Pechtold L.A., Abraham W., Potts R.O. The influence of an electric field on ion and water accessibility to stratum corneum lipid lamellae. Pharm. Res. 13:1996;1168-1173.
    • (1996) Pharm. Res. , vol.13 , pp. 1168-1173
    • Pechtold, L.A.1    Abraham, W.2    Potts, R.O.3
  • 119
    • 0030937460 scopus 로고    scopus 로고
    • In vivo human skin permeability enhancement by oleic acid: Transepidermal water loss and Fourier-transform infrared spectroscopy studies
    • Tanojo H., Junginger H.E., Bodde H.E. In vivo human skin permeability enhancement by oleic acid: Transepidermal water loss and Fourier-transform infrared spectroscopy studies. J. Control. Release. 47:1997;31-39.
    • (1997) J. Control. Release , vol.47 , pp. 31-39
    • Tanojo, H.1    Junginger, H.E.2    Bodde, H.E.3
  • 121
    • 0032450782 scopus 로고    scopus 로고
    • Electroperturbation of human stratum corneum fine structure by high voltage pulses: A freeze fracture electron microscopy and differnetial thermal analysis
    • in press
    • A. Jadoul, H. Tanajo, V. Preat, F. Spies, H.E. Bodde, Electroperturbation of human stratum corneum fine structure by high voltage pulses: A freeze fracture electron microscopy and differnetial thermal analysis, J. Invest. Derm. (1998) in press.
    • (1998) J. Invest. Derm.
    • Jadoul, A.1    Tanajo, H.2    Preat, V.3    Spies, F.4    Bodde, H.E.5
  • 123
    • 0000180845 scopus 로고
    • Electro-incorporation of microcarriers as a method for the transdermal delivery of large molecules
    • Hofmann G.A., Rustrum W.V., Suder K.S. Electro-incorporation of microcarriers as a method for the transdermal delivery of large molecules. Bioelectrochem. Bioenerg. 38:1995;209-222.
    • (1995) Bioelectrochem. Bioenerg. , vol.38 , pp. 209-222
    • Hofmann, G.A.1    Rustrum, W.V.2    Suder, K.S.3
  • 124
    • 0029892620 scopus 로고    scopus 로고
    • Depth-targeted efficient gene delivery and expression in the skin by pulsed electric fields: An approach to gene therapy of skin aging and other diseases
    • Zhang L., Li L., Hoffmann G.A., Hoffman R.M. Depth-targeted efficient gene delivery and expression in the skin by pulsed electric fields: an approach to gene therapy of skin aging and other diseases. Biochem. Biophys. Res. Commun. 220:1996;633-636.
    • (1996) Biochem. Biophys. Res. Commun. , vol.220 , pp. 633-636
    • Zhang, L.1    Li, L.2    Hoffmann, G.A.3    Hoffman, R.M.4
  • 125
    • 0031149897 scopus 로고    scopus 로고
    • In vivo transdermal delivery of large molecules by pressure-mediated electroincorporation and electroporation: A novel method for drug and gene delivery
    • Zhang L., Li L.N., An Z.L., Hoffman R.M., Hofmann G.A. In vivo transdermal delivery of large molecules by pressure-mediated electroincorporation and electroporation: a novel method for drug and gene delivery. Bioelectrochem. Bioenerg. 42:1997;283-292.
    • (1997) Bioelectrochem. Bioenerg. , vol.42 , pp. 283-292
    • Zhang, L.1    Li, L.N.2    An, Z.L.3    Hoffman, R.M.4    Hofmann, G.A.5
  • 126
  • 127
    • 0344575015 scopus 로고    scopus 로고
    • Low intensity ultrasound as a probe to elucidate the relative follicular contribution to total transdermal absorption
    • V.M. Meidan, M. Docker, A.D. Walmsley, W.J. Irwin, Low intensity ultrasound as a probe to elucidate the relative follicular contribution to total transdermal absorption, Pharm. Res. (1997).
    • (1997) Pharm. Res.
    • Meidan, V.M.1    Docker, M.2    Walmsley, A.D.3    Irwin, W.J.4
  • 128
    • 0024819965 scopus 로고
    • Tissue electroporation: Observation of reversible electrical breakdown in viable frog skin
    • Powell K.T., Morgenthaler A.W., Weaver J.C. Tissue electroporation: observation of reversible electrical breakdown in viable frog skin. Biophys. J. 56:1989;1163-1171.
    • (1989) Biophys. J. , vol.56 , pp. 1163-1171
    • Powell, K.T.1    Morgenthaler, A.W.2    Weaver, J.C.3
  • 129
    • 0032450651 scopus 로고    scopus 로고
    • Skin electroporation causes molecular transport across the stratum corneum through localized transport regions
    • in press
    • T. Chen, R. Langer, J.C. Weaver, Skin electroporation causes molecular transport across the stratum corneum through localized transport regions, J. Invest. Dermatol. (1998) in press.
    • (1998) J. Invest. Dermatol.
    • Chen, T.1    Langer, R.2    Weaver, J.C.3
  • 130
    • 0030922369 scopus 로고    scopus 로고
    • Characterization of electric-pulse-induced permeabilization of porcine skin using surface electrodes
    • Gallo S.A., Oseroff A.R., Johnson P.G., Hui S.W. Characterization of electric-pulse-induced permeabilization of porcine skin using surface electrodes. Biophys. J. 72:1997;2805-2811.
    • (1997) Biophys. J. , vol.72 , pp. 2805-2811
    • Gallo, S.A.1    Oseroff, A.R.2    Johnson, P.G.3    Hui, S.W.4
  • 132
  • 133
    • 0028093040 scopus 로고
    • A linear theory of transdermal transport phenomena
    • Edwards D.A., Langer R. A linear theory of transdermal transport phenomena. J. Pharm. Sci. 83:1994;1315-1334.
    • (1994) J. Pharm. Sci. , vol.83 , pp. 1315-1334
    • Edwards, D.A.1    Langer, R.2
  • 134
    • 0025358755 scopus 로고
    • DC electrical properties of frozen, excised human skin
    • Kasting G.G., Bowman L.A. DC electrical properties of frozen, excised human skin. Pharmacol. Res. 7:1990;134-143.
    • (1990) Pharmacol. Res. , vol.7 , pp. 134-143
    • Kasting, G.G.1    Bowman, L.A.2


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