Stratum corneum lipids of human epidermal keratinocyte air-liquid cultures: Implications for barrier function

Pharmaceutical Research

Volumn 13, Issue 8, 1996, Pages 1162-1167

  Kennedy, Alane H ^a   Golden, Guia M ^a   Gay, Carol L ^b   Guy, Richard H ^b   Francoeur, Michael L ^a   Mak, Vivien H W ^c  

^a PFIZER INC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Adamis Pharmaceuticals Corporation   (United States)

Author keywords

Keratinocyte cultures; Skin barrier function; Stratum corneum lipids

Indexed keywords

ARTICLE; CELL CULTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFRARED SPECTROPHOTOMETRY; KERATINOCYTE; LIPID COMPOSITION; PERMEABILITY BARRIER; PHASE TRANSITION; PRIORITY JOURNAL; STRATUM CORNEUM; THIN LAYER CHROMATOGRAPHY;

AIR; EPIDERMIS; HUMANS; KERATINOCYTES; LIPID METABOLISM; MICROSCOPY, ELECTRON; PERMEABILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE; WATER;

EID: 0029764146     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016047816699     Document Type: Article

References (30)

1. V. H. W. Mak, M. B. Cumpstone, A. H. Kennedy, C. S. Harmon, R. H. Guy, R. O. Potts. Barrier function of human keratinocyte cultures grown at the air-liquid interface. J Invest Dermatol. 96:323-327 (1991).
2. R. J. Scheuplein and I. H. Blank. Permeability of the skin. Physiol Rev 51:701-747 (1971).
3. W. J. Albery and J. Hadgraft. Percutaneous absorption: in vivo experiments. J Pharm Pharmacol 31:140-147 (1979).
4. G. M. Golden, D. B. Guzek, A. H. Kennedy, J. E. McKie, R. O. Potts. Stratum corneum lipid phase transitions and water barrier properties. Biochem 26:2382-2388 (1987).
5. D. C. Swartzendruber, P. W. Wertz, D. J. Kitko, K. C. Madison, D. T. Downing. Molecular models of the intercellular lamellae in mammalian stratum corneum. J Invest Dermatol. 92:251-257 (1989).
6. S. Y. E. Hou, A. K. Mitra, S. H. White, G. K. Menon, R. Ghadially, P. M. Elias. Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and X-ray diffraction. J Invest Dermatol. 96:215-223 (1991).
7. H. E. Bodde, B. Holman, F. Spies, A. Weerheim, J. Kempenaar, M. Mammaas, M. Ponec. Freeze-fracture electron microscopy of in vitro reconstructed human epidermis. J Invest Dermatol 95:108-116 (1990).
8. G. F. Odland, K. Holbrook: The lamellar granules of epidermis. Curr Probl Derm 9:29-49 (1981).
9. L. Landmann. The epidermal permeability barrier. Comparison between in vivo and in vitro lipid structures. Eur J Cell Biol 33:258-264 (1984).
10. L. Landmann. Epidermal permeability barrier: transformation of lamellar granules-disks into intercellular sheets by a membrane-fusion process, a freeze-fracture study. J Invest Dermatol 87:202-209 (1986).
11. P. W. Wertz, D. C. Swartzendruber, D. J. Kitko, K. C. Madison, D. T. Downing. The role of the corneocyte lipids envelopes in cohesion of stratum corneum. J Invest Dermatol 93:169-172 (1989).
12. G. K. Menon, P. M. Elias. Ultrastructure localization of calcium in psoriatic and normal human epidermis. Arch Dermatol 127:57-63 (1991).
13. B. Melnik, J. Hollmann, U. Hofmann, M. S. Yuh, G. Plewig. Lipid composition of outer stratum corneum and nails in atopic and control subjects. Arch Dermatol Res 282:549-551 (1990).
14. K. R. Feingold, B. E. Brown, S. R. Lear, A. H. Moser, P. M. Elias. Effect of essential fatty acid deficiency on cutaneous sterol synthesis. J Invest Dermatol 87:588-591 (1986).
15. C. Schmidt, N. S. Pennys, V. A. Ziboh, I. Kiem, J. Schlossberg. Cholesterol and cholesterol ester content in normal and pathological scale. J Invest Dermatol 68:206-209 (1977).
16. K. K. Mustakallio, U. Kiistala, H. J. Piha, E. Nieminen. Epidermal lipids in Besnier's prurigo (atopic dermatitis). Ann Med Exp Fenn 45:323-325 (1967).
17. P. J. Hartop, C. F. Allenby, C. Prottey. Comparison of barrier function and lipids in psoriasis and essential fatty acid-deficient rats. Clin Exptal Dermatol 3:259-267 (1978).
18. Y. Werner, M. Linberg. Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis. Acta Derm Venereol 65:102-105 (1985).
19. A. W. Fulmer, G. J. Kramer. Stratum corneum lipid abnormalities in surfactant-induced dry scaly skin. J Invest Dermatol 86:598-602 (1986).
20. G. Grubauer, K. R. Feingold, R. M. Harris, P. M. Elias. Lipid content and lipid type as determinants of the epidermal permeability barrier. J Lipid Res 30:89-96 (1989).
21. G. M. Golden, D. B. Guzek, R. R. Harris, J. E. McKie, R. O. Potts. Lipid thermotropic transitions in human stratum corneum. J Invest Dermatol 86:255-259 (1986).
22. B. F. van Duzee. Thermal analysis of human stratum corneum. J Invest Dermatol 65:404-408 (1975).
23. J. Umemura, D. G. Cameron, H. H. Mantsch. A Fourier transform infrared spectroscopic study of the molecular interaction of cholesterol with DPPC. Biochim Biophys Acta 602:32-44 (1980).
24. J. A. Bouwstra, G. S. Gooris, J. A. van der Spek, W. Bras. Structural investigations of human stratum corneum by small-angle x-ray scattering. J Invest Dermatol 97:1005-1012 (1991).
25. D. S. Johnston, D. Chapman. A calorimetric study of the thermotropic behavior of mixtures of brain cerebrosides with other brain lipids. Biochimica et Biophysica Acta 939:603-614 (1988).
26. J. B. Finean, W. Hutchinson. X-ray diffraction studies of lipid phase transitions in cholesterol-rich membranes at sub-zero temperatures. Chemistry and Physics of Lipids 46:63-71 (1988).
27. S. H. White, D. Mirejovsky, G. I. King. Structure of lamellar lipid domains and comeocyte envelopes of murine stratum corneum. An X-ray diffraction study. Biochem 27:3725-3732 (1988).
28. G. Grubauer, K. R. Feingold, PM Elias. Relationship of epidermal lipid synthesis to cutaneous barrier function. J Lipid Res 28:746-752 (1987).
29. K. R. Feingold, M. Mao-Qiang, E. Proksch, G. K. Menon, B. E. Brown, P. M. Elias. The lovastatin-treated rodent: a new model of barrier disruption and epidermal hyperplasia. J Invest Dermatol 96:201-209 (1991).
30. E. Proksch, K. R. Feingold, M. Mao-Qiang, P. M. Elias. Barrier function regulates epidermal DNA synthesis. J Clin Invest 87:1668-1673 (1991).