Solid-phase synthesis of potential aspartic acid protease inhibitors containing a hydroxyethylamine isostere

Tetrahedron Letters

Volumn 40, Issue 14, 1999, Pages 2729-2732

  Zhou, Jinglan ^a   Termin, Andreas ^a   Wayland, Melissa ^a   Tarby, Christine M ^a  

^a Formerly CombiChem Inc   (United States)

Author keywords

Aspartic acid protease; Hydroxyethylamine isostere; Inhibitors; Solid phase synthesis

Indexed keywords

1,3 DIAMINO 2 PROPANOL; ASPARTIC ACID; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 0033515729     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00351-2     Document Type: Article

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17. 3) δ 20.0, 27.9, 31.2, 38.8, 40.8, 42.8, 43.7, 51.2, 56.9, 70.7, 109.2, 110.1, 113.2, 122.5, 124.0, 128.9, 130.2, 131.1, 142.8, 150.0, 154.7, 172.2, 173.6.
18. 3) δ 20.1, 27.5, 29.9, 39.1, 43.8, 50.3, 59.0, 71.0, 101.7, 108.0, 108.5, 121.5, 126.2, 126.7, 127.4, 128.8, 129.3, 130.5, 131.3, 136.3, 139.3, 141.1, 148.0, 149.0, 171.6, 174.0.