Screening of fungal species for fumonisin production and fumonisin-like disruption of sphingolipid biosynthesis

Mycopathologia

Volumn 146, Issue 2, 1999, Pages 91-98

  Norred, William P ^a   Bacon, Charles W ^a   Riley, Ronald T ^a   Voss, Kenneth A ^a   Meredith, Filmore I ^a  

^a RUSSELL RESEARCH CENTER   (United States)

Author keywords

Bioassay; Ceramide; Fumonisins; Fungi; Sphingolipids; Tissue slices

Indexed keywords

ANIMALIA; FUNGI; FUSARIA; FUSARIUM; FUSARIUM MONILIFORME; FUSARIUM PROLIFERATUM; GIBBERELLA FUJIKUROI; POACEAE; ZEA MAYS;

EID: 0033493906     PISSN: 0301486X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007036709624     Document Type: Article

References (26)

1. Merrill AH, Jr. Cell regulation by sphingosine and more complex sphingolipids. J Bioenergetics Biomembranes 1991; 23: 83-104.
2. Hannun YA, Bell RM. Functions of sphingolipids and sphingolipid breakdown products in cellular regulation. Science 1989; 243: 500-507.
3. Wang E, Norred WP, Bacon CW, Riley RT, Merrill AH, Jr. Inhibition of sphingolipid biosynthesis by fumonisins: implications for diseases associated with Fusarium moniliforme. J Biol Chem 1991; 266: 14486-14490.
4. 1 in feeds associated with animal health problems. Mycopathologia 1991; 114: 129-135.
5. Sydenham EW, Shephard GS, Thiel PG, Marasas WFO, Stockenström S. Fumonisin contamination of commercial corn-based human foodstuffs. J Agric Food Chem 1991; 39: 2014-2018.
6. Zweerink MM, Edison AM Wells GB, Pinto W, Lester RL. Characterization of a novel, potent, and specific inhibitor of serine palmitoyltransferase. J Biol Chem 1992; 267: 25032-25038.
7. 1 in corn naturally contaminated with aflatoxins. Food Chem Toxicol 1993, 13: 995-998.
8. 3 content of Iowa, Wisconsin, and Illinois corn and corn screenings. J Agr Food Chem 1993; 41: 263-266.
9. 1 in corn-containing foods. J Agric Food Chem 1993; 41: 1655-1658.
10. Riley RT, Wang E, Merrill AH, Jr. Liquid chromatographic determination of sphinganine and sphingosine: Use of the free sphinganine- to sphingosine ratio as a biomarker for consumption of fumonisins. J Assoc Off Analyt Chem Int 1994; 77: 533-540.
11. Merrill AH, Jr., Schmelz E-M, Wang E, Schroeder JJ, Dillehay DL, Riley RT. Role of dietary sphingolipids and inhibitors of sphingolipid metabolism in cancer and other diseases. J Nutr 1995; 125 Suppl. 1677S-1682S.
12. Mandala SM, Thornton RA Fromer BR, Curotto JE, Rozdilsky W, Kurtz MB, Giacobbe RA, Bills GF, Cabello MA, Martin I, Pelaez F, Harris GH. The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporormiella austalis. J Antibiotics 1995; 48: 349-356.
13. Yoo H-S, Norred WP, Showker J, Riley RT. Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity. Toxicol Appl Pharmacol 1996; 138: 211-218.
14. Norred WP, Riley RT, Meredith FI, Bacon CW, Voss KA. Time- and dose-response effect of the mycotoxin, fumonisin B i, on sphingoid base elevations in precision-cut rat liver and kidney slices. Toxicol In Vitro 1996; 10: 349-358.
15. Merrill AH, Jr., Wang E, Vales TR, Smith ER, Schroeder JJ, Menaldino DS, Alexander C, Crane HM, Xia J, Liotta DC, Meredith FI, Riley RT. Fumonisin toxicity and sphingolipid biosynthesis. Adv Exp Med Biol 1996; 392: 297-306.
16. Spiegel S, Merrill AH:, Jr. Sphingolipid metabolism and cell growth regulation. FASEB J 1996; 10: 1388-1397.
17. Merrill AH, Jr., Schmelz EM, Dillehay DL, Spiegel S, Shayman JA, Schroeder JJ, Riley RT, Voss KA, Wang E. Sphingolipids - The enigmatic lipid class: Biochemistry, physiology, and pathophysiology. Toxicol Appl Pharmacol 1997; 142: 208-225.
18. Merrill AH, Jr., Schmelz EM, Wang E, Dillehay DL, Rice LG, Meredith F, Riley RT. Importance of sphingolipids and inhibitors of sphingolipid metabolism as components of animal diets. J Nutr 1997; 127 Suppl. 830S-833S.
19. Klittich CJR, Leslie IF, Nelson PE, Marasas WFO. Fusarium thapsinum (Gibberella thapsina): A new species in section Liseola from sorghum. Mycologia 1997 89: 643-652.
20. Norred WP, Plattner RD, Dombrink-Kurtzman MA, Meredith FI, Riley RT. Mycotoxin-induced elevation of free sphingoid bases in precision-cut rat liver slices: Specificity of the response and structure-activity relationships. Toxicol Appl Pharmacol 1997; 147: 63-70.
21. 1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol Appl Pharmacol 1998; 148: 252-260.
22. 3 cause hepato- and nephrotoxicity in rats. Mycopathologia 1998; 141: 45-58.
23. Hawksworth DL. The fungal dimension of biodiversity: magnitude, significance, and conservation. Mutation Res 1991; 95: 641-655.
24. Riley RT. Mechanistic interactions of mycotoxins: theoretical considerations. In: Sinha KK, Bhatnagar D, eds. Mycotoxins in agriculture and food safety. New York: Marcel Dekker; Inc, 1998: 227-253.
25. Miyake Y, Kozutsumi Y, Nakamura S, Fujita T, Kawasaki T. Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin. Biochem Biophys Res Commun 1995; 211: 396-403.
26. Riley RT, Voss. KA, Norred, WP, Bacon CW, Meredith, FI and Sharma RP. Serine palmitoyltransfersase inhibition reverses antiproliferative effects of ceramide synthase inhibition in cultured renal cells and suppresses free sphingoid base accumulation in kidney of BALBc mice. Environ Toxicol Pharmacol 1999; 7: 109-118.