An anchorage nuclear structure for telomeric DNA repeats in HeLa cells

Chromosome Research

Volumn 7, Issue 8, 1999, Pages 581-592

  Pierron, Gérard ^a   Puvion Dutilleul, Francine ^a  

^a Institute de Recherche sur le Cancer   (France)

Author keywords

Ad5; HeLa cells; HSV1; In situ hybridization; PNA; Telomeres

Indexed keywords

DIGOXIGENIN; HYPOTONIC SOLUTION; NUCLEOPROTEIN; PEPTIDE NUCLEIC ACID; REPETITIVE DNA; VIRUS DNA;

ARTICLE; BIOTINYLATION; CELL NUCLEUS; CELL ULTRASTRUCTURE; DNA PROBE; HELA CELL; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; TELOMERE;

CELL NUCLEUS; DNA; HELA CELLS; HUMANS; INTERPHASE; REPETITIVE SEQUENCES, NUCLEIC ACID; TELOMERE;

ADENOVIRIDAE; DNA VIRUSES; HERPES; HUMAN ADENOVIRUS TYPE 5; HUMAN HERPESVIRUS 1;

EID: 0033405221     PISSN: 09673849     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009253917125     Document Type: Article

References (45)

1. Babich A, Feldman LT, Nevins JR, Darnell JE, Weinberger C (1983) Effect of adenovirus on metabolism of specific mRNAs: transport control and specific translation discrimination. Mol Cell Biol 3: 1212-1221.
2. Bertuch A, Lundblad V (1998) Telomeres and double-strand breaks: trying to make ends meet. Trends Cell Biol 8: 339-342.
3. Besse S, Puvion-Dutilleul F (1994) Compartmentalization of cellular and viral DNA in adenovirus type 5 infection as revealed by ultrastructural in situ hybridization. Chromosome Res 2: 123-135.
4. Besse S, Puvion-Dutilleul F (1996) Distribution of ribosomal genes in nucleoli of herpes simplex virus type 1 infected cells. Eur J Cell Biol 71: 33-44.
5. Bilaud T, Brun C, Ancelin K, Koering CE, Laroche T, Gilson E (1997) Telomeric localization of TFR2, a novel human telobox protein. Nature Genet 17: 236-239.
6. Blackburn EH (1991) Structure and function of telomeres. Nature 350: 569-573.
7. Blackburn EH (1992) Telomerases. Annu Rev Biochem 61: 113-129.
8. Blasco MA, Lee HW, Hande MP et al. (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91: 25-34.
9. Bodnar AG, Ouellette M, Frolkis M et al. (1998) Extension of lifespan by introduction of telomerase into normal human cells. Science 279: 349-352.
10. Bourns BD, Alexander MK, Smith AM, Zakian VA (1998) Sir proteins, Rif proteins, and Cde13p bind Saccharomyces telomeres in vivo. Mol Cell Biol 18: 5600-5608.
11. Brasch K, Ochs RL (1992) Nuclear bodies (NBs): a newly 'rediscovered' organelle. Exp Cell Res 202: 211-223.
12. Broccoli D, Smogorzewska A, Chong L, de Lange T (1997) Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nature Genet 17: 231-235.
13. Chong L, van Steensel B, Broccoli D et al. (1995) A human telomeric protein. Science 270: 1663-1667.
14. Cooke HJ, Smith BA (1986) Variability at the telomeres of the human X/Y pseudoautosomal region. Cold Spring Harb Symp Quant Biol 51: 213-219.
15. de Lange T (1992) Human telomeres are attached to the nuclear matrix. Embo J 11: 717-724.
16. Dong F, Jiang J (1998) Non-Rabl patterns of centromere and telomere distribution in the interphase nuclei of plant cells. Chromosome Res 6: 551-558.
17. Egholm M, Buchardt O, Christensen L et al. (1993) PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature 365: 566-568.
18. Gilson E, Laroche T, Gasser S (1993) Telomeres and the functional architecture of the nucleus. Trends Cell Biol 3: 128-134.
19. Gotta M, Laroche T, Formenton A, Maillet L, Scherthan H, Gasser SM (1996) The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisae. J Cell Biol 134: 1349-1363.
20. Gravel S, Larrivee M, Labrecque P, Wellinger RJ (1998) Yeast Ku as regulator of chromosomal DNA end structure. Science 280: 741-744.
21. Greider CW (1998) Telomeres and senescence: the history, the experiment, the future, Curr Biol 8: 178-181.
22. Hardwicke MA, Sandri-Goldin RM (1994) The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection. J Virol 68: 4797-4810.
23. Henderson ER, Blackburn EH (1989) An overhanging 3′ terminus is a conserved feature of telomeres. Mol Cell Biol 9: 345-348.
24. Henderson S, Allsopp R, Spector D, Wang SS, Harley C (1996) In situ analysis of changes in telomere size during replicative aging and cell transformation. Chromosome Res 134: 1-12.
25. Jiang XR, Jimenez G, Chang E et al. (1999) Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nature Genet 21: 111-114.
26. Lansdorp PM, Verwoerd NP, van de Rijke FM et al. (1996) Heterogeneity in telomere length of human chromosomes. Hum Mol Genet 5: 685-691.
27. Lee HW, Blasco MA, Gottlieb GJ, Horner JW, Greider CW, DePinho RA (1998) Essential role of mouse telomerase in highly proliferative organs. Nature 392: 569-574.
28. Lingner J, Cech TR (1996) Purification of telomerase from Euplotes aediculatus: requirement of a primer 3′ overhang. Proc Natl Acad Sci USA 93: 10712-10717.
29. Luderus MEEE, van Steensel B, Chong L, Sibon OCM, Cremers FFM, de Lange T (1996) Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J Cell Biol 4: 867-881.
30. Lundblad V, Szostak JW (1989) A mutant with a defect in telomere elongation leads to senescence in yeast. Cell 57: 633-643.
31. McElligott R, Wellinger RJ (1997) The terminal DNA structure of mammalian chromosomes. EMBO J 16: 3705-3714.
32. Nakamura TM, Morin GB, Chapman KB et al. (1997) Telomerase catalytic subunit homologs from fission yeast and human. Science 277: 955-959.
33. Olovnikov AM (1973) A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. Theor Biol 41: 181-190.
34. Puvion E, Puvion-Dutilleul F (1996) Ultrastructure of the nucleus in relation to transcription and splicing: role of perichromatin fibrils and interchromatin granules. Exp Cell Res 229: 217-225.
35. Puvion-Dutilleul F (1998) Electron microscope in situ hybridization: the nonisotopic postembedding procedure. In: Wilkinson DG, ed. In situ Hybridization: A Practical Approach. Oxford, UK: Oxford University Press, pp 127-160.
36. Puvion-Dutilleul F, Besse S (1994) Induction of complete segregation of cellular DNA and non-encapsidated viral genomes in herpes simplex virus type 1 infected HeLa cells as revealed by in situ hybridization. Chromosoma 103: 104-110.
37. Puvion-Dutilleul F, Puvion E (1980) New aspects of intranuclear structures following partial decondensation of chromatin: a cytochemical and high resolution autoradiographical study. J Cell Sci 42: 305-322.
38. Puvion-Dutilleul F, Besse S, Pichard E, Cajean-Feroldi C (1998) Release of viruses and viral DNA from nucleus to cytoplasm of HeLa cells at late stages of productive adenovirus infection as revealed by electron microscope in situ hybridization. Biol Cell 90: 5-38.
39. Roth J, Bendayan M, Carlemalm E, Villiger EW (1981) Enhancement of structural preservation and immunocytochemical staining in low temperature embedded pancreatic tissue. J Histochem Cytochem 29: 663-671.
40. Smith S, Giriat I, Schmitt A, de Lange T (1998) Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 282: 1484-1487.
41. Steinmüller J, Schleiermacher E, Scherthan H (1993) Direct detection of repetitive, whole chromosome paint and telomere DNA probes by immunogold electron microscopy. Chromosome Res 1: 45-51.
42. van Steensel B, de Lange T (1997) Control of telomere length by the human telomeric protein TRF1. Nature 385: 740-743.
43. van Steensel B, Smogorzewska A, de Lange T (1998) TRF2 protects human telomeres from end-to-end fusions. Cell 92: 401-413.
44. Vaziri H, Benchimol S (1998) Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr Biol 8: 279-282.
45. 3 repeats. Proc Natl Acad Sci USA 94: 7423-7428.