Influence of smoking and donor age on the spectrum of in vivo mutation at the HPRT-locus in T lymphocytes of healthy adults

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 431, Issue 2, 1999, Pages 325-339

  Podlutsky, Andrej ^a   Hou, Sai Mei ^a   Nyberg, Fredrik ^a   Pershagen, Göran ^a   Lambert, Bo ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Ageing; Human; Hypoxanthine guanine phosphoribosyltransferase (HPRT) gene; In vivo; Mutational spectra; Smoking; T lymphocyte

Indexed keywords

ARTICLE; GENE FREQUENCY; GENE INSERTION; GENE LOCUS; GENE MUTATION; HUMAN; MISSENSE MUTATION; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; SMOKING;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BASE PAIR MISMATCH; FRAMESHIFT MUTATION; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MIDDLE AGED; MUTATION; RNA SPLICING; SEQUENCE DELETION; SMOKING; SWEDEN; T-LYMPHOCYTES; THIOGUANINE; VARIATION (GENETICS);

EID: 0033385565     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00176-1     Document Type: Article

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