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Volumn 17, Issue 9, 1996, Pages 1871-1883

Spectrum of somatic mutation at the hypoxanthine phosphoribosyltransferase (hprt) gene of healthy people

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

EID: 0029837679     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.9.1871     Document Type: Article
Times cited : (45)

References (54)
  • 2
    • 0028157494 scopus 로고
    • Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo
    • Cole, J. and Skopek, T.R. (1994) Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo. Mutat. Res., 304, 33-105.
    • (1994) Mutat. Res. , vol.304 , pp. 33-105
    • Cole, J.1    Skopek, T.R.2
  • 3
    • 0024854474 scopus 로고
    • Molecular analyses of in vivo hprt mutations in human lymphocytes: III. Longitudinal study of hprt gene structural alterations and T-cell clonal origins
    • Nicklas, J.A., Hunter, T.C., O'Neill, J.P. and Albertini, R.J. (1989) Molecular analyses of in vivo hprt mutations in human lymphocytes: III. Longitudinal study of hprt gene structural alterations and T-cell clonal origins. Mutat. Res., 215, 147-160.
    • (1989) Mutat. Res. , vol.215 , pp. 147-160
    • Nicklas, J.A.1    Hunter, T.C.2    O'Neill, J.P.3    Albertini, R.J.4
  • 4
    • 0025017202 scopus 로고
    • In vivo hprt mutant frequencies in T-cells of normal human newborns
    • McGinniss, M.J., Falta, M.T., Sullivan, L.M. and Albertini, R.J. (1990) In vivo hprt mutant frequencies in T-cells of normal human newborns. Mutat. Res., 240, 117-126.
    • (1990) Mutat. Res. , vol.240 , pp. 117-126
    • McGinniss, M.J.1    Falta, M.T.2    Sullivan, L.M.3    Albertini, R.J.4
  • 5
    • 0024828476 scopus 로고
    • Molecular analyses of in vivo hprt mutations in human T-lymphocytes: IV. Studies in newborns
    • McGinniss, M.J., Nicklas, J.A. and Albertini, R.J. (1989) Molecular analyses of in vivo hprt mutations in human T-lymphocytes: IV. Studies in newborns. Environ. Mol. Mutagen., 14, 229-237.
    • (1989) Environ. Mol. Mutagen. , vol.14 , pp. 229-237
    • McGinniss, M.J.1    Nicklas, J.A.2    Albertini, R.J.3
  • 6
    • 0028147748 scopus 로고
    • Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: Statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age
    • Finette, B.A., Sullivan, L.M., O'Neill, J.P., Nicklas, J.A., Vacek, P.M. and Albertini, R.J. (1994) Determination of hprt mutant frequencies in T-lymphocytes from a healthy pediatric population: statistical comparison between newborn, children and adult mutant frequencies, cloning efficiency and age. Mutat. Res., 308, 223-231.
    • (1994) Mutat. Res. , vol.308 , pp. 223-231
    • Finette, B.A.1    Sullivan, L.M.2    O'Neill, J.P.3    Nicklas, J.A.4    Vacek, P.M.5    Albertini, R.J.6
  • 7
    • 0026323394 scopus 로고
    • V(D)J recombinase-like activity mediates hprt gene deletion in human fetal T-lymphocytes
    • Fuscoe, J.C., Zimmerman, L.J., Lippert, M.J., Nicklas, J.A. and Albertini, R.J. (1991) V(D)J recombinase-like activity mediates hprt gene deletion in human fetal T-lymphocytes. Cancer Res., 51, 6001-6005.
    • (1991) Cancer Res. , vol.51 , pp. 6001-6005
    • Fuscoe, J.C.1    Zimmerman, L.J.2    Lippert, M.J.3    Nicklas, J.A.4    Albertini, R.J.5
  • 8
    • 0027930348 scopus 로고
    • An analysis of in vivo hprt mutant frequency in circulating T-lymphocytes in the normal human population: A comparison of four datasets
    • Robinson, D.R., Goodall, K., Albertini, R.J. et al. (1994) An analysis of in vivo hprt mutant frequency in circulating T-lymphocytes in the normal human population: a comparison of four datasets. Mutat. Res., 313, 227-247.
    • (1994) Mutat. Res. , vol.313 , pp. 227-247
    • Robinson, D.R.1    Goodall, K.2    Albertini, R.J.3
  • 10
    • 0027974704 scopus 로고
    • Software for the analysis of mutations at the human hprt gene
    • Cariello, N.F. (1994) Software for the analysis of mutations at the human hprt gene. Mutat. Res., 312, 173-185.
    • (1994) Mutat. Res. , vol.312 , pp. 173-185
    • Cariello, N.F.1
  • 11
    • 0027255852 scopus 로고
    • Analysis of mutations occurring at the human hprt locus
    • Cariello, N.F. and Skopek, T.R. (1993) Analysis of mutations occurring at the human hprt locus. J. Mol. Biol., 231, 41-57.
    • (1993) J. Mol. Biol. , vol.231 , pp. 41-57
    • Cariello, N.F.1    Skopek, T.R.2
  • 13
    • 0028296459 scopus 로고
    • Why use somatic mutations for human biomonitoring?
    • Albertini, R.J. (1994) Why use somatic mutations for human biomonitoring? Environ. Mol. Mutagen., 23 (Suppl. 24), 18-22.
    • (1994) Environ. Mol. Mutagen. , vol.23 , Issue.24 SUPPL. , pp. 18-22
    • Albertini, R.J.1
  • 15
    • 0027156738 scopus 로고
    • Characterization of in vivo somatic mutations at the hypoxanthine phosphoribosyltransferase gene of a human control population
    • Burkhart-Schultz, K., Thomas, C.B., Thompson, C.L., Strout, C.L., Brinson, E. and Jones, I.M. (1993) Characterization of in vivo somatic mutations at the hypoxanthine phosphoribosyltransferase gene of a human control population. Environ. Health Perspect., 101, 68-74.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 68-74
    • Burkhart-Schultz, K.1    Thomas, C.B.2    Thompson, C.L.3    Strout, C.L.4    Brinson, E.5    Jones, I.M.6
  • 16
    • 0023131909 scopus 로고
    • Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans
    • O'Neill, J.P., McGinniss, M.J., Berman, J.K., Sullivan, L.M., Nicklas, J.A. and Albertini, R.J. (1987) Refinement of a T-lymphocyte cloning assay to quantify the in vivo thioguanine-resistant mutant frequency in humans. Mutagenesis, 2, 87-94.
    • (1987) Mutagenesis , vol.2 , pp. 87-94
    • O'Neill, J.P.1    McGinniss, M.J.2    Berman, J.K.3    Sullivan, L.M.4    Nicklas, J.A.5    Albertini, R.J.6
  • 18
    • 0024375359 scopus 로고
    • Molecular basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in ten subjects determined by direct sequencing of amplified transcripts
    • Davidson, B.L., Tarle, S.A., Palella, T.D. and Kelley, W.N. (1989) Molecular basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in ten subjects determined by direct sequencing of amplified transcripts. J. Clin. Invest., 84, 342-346.
    • (1989) J. Clin. Invest. , vol.84 , pp. 342-346
    • Davidson, B.L.1    Tarle, S.A.2    Palella, T.D.3    Kelley, W.N.4
  • 19
    • 1842267323 scopus 로고
    • Identification of mutations leading to the Lesch-Nyhan syndrome by automated direct DNA sequencing of in vitro amplified cDNA
    • Gibbs, R.A., Nguyen, P-N., McBride, L.J., Koepf, S.M. and Caskey, C.T. (1989) Identification of mutations leading to the Lesch-Nyhan syndrome by automated direct DNA sequencing of in vitro amplified cDNA. Proc. Natl Acad. Sci. USA, 86, 1919-1923.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 1919-1923
    • Gibbs, R.A.1    Nguyen, P.-N.2    McBride, L.J.3    Koepf, S.M.4    Caskey, C.T.5
  • 20
    • 0024407957 scopus 로고
    • Amplification and direct nucleotide sequencing of cDNA from the lysate of low numbers of diploid human cells
    • Yang, J.-L., Maher, V.M. and McCormick, J.J. (1989) Amplification and direct nucleotide sequencing of cDNA from the lysate of low numbers of diploid human cells. Gene, 83, 347-354.
    • (1989) Gene , vol.83 , pp. 347-354
    • Yang, J.-L.1    Maher, V.M.2    McCormick, J.J.3
  • 21
    • 0025282802 scopus 로고
    • Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltranferase gene in Lesch-Nyhan families
    • Gibbs, R.A., Nguyen, P.-N., Edwards, A., Civitello, A.B. and Caskey, C.T. (1990) Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltranferase gene in Lesch-Nyhan families. Genomics, 7, 235-244.
    • (1990) Genomics , vol.7 , pp. 235-244
    • Gibbs, R.A.1    Nguyen, P.-N.2    Edwards, A.3    Civitello, A.B.4    Caskey, C.T.5
  • 22
    • 0023264512 scopus 로고
    • Statistical test for the comparison of samples from mutational spectra
    • Adams, W.T. and Skopek, T.R. (1987) Statistical test for the comparison of samples from mutational spectra. J. Mol. Biol., 194, 391-396.
    • (1987) J. Mol. Biol. , vol.194 , pp. 391-396
    • Adams, W.T.1    Skopek, T.R.2
  • 23
    • 0009175063 scopus 로고
    • Seattle: StatSci, a division of MathSoft, Inc.
    • Statistical Sciences, Inc. (1993) S-PLUS Reference Manual, Version 3.2, Seattle: StatSci, a division of MathSoft, Inc.
    • (1993) S-PLUS Reference Manual, Version 3.2
  • 24
    • 0001216741 scopus 로고
    • A representation for multinomial cumulative distribution functions
    • Levin, B. (1981) A representation for multinomial cumulative distribution functions. Ann. Stat., 9, 1123-1126.
    • (1981) Ann. Stat. , vol.9 , pp. 1123-1126
    • Levin, B.1
  • 25
    • 0000923895 scopus 로고
    • An inequality involving multinomial probabilities
    • Mallows, C.L. (1968) An inequality involving multinomial probabilities. Biometrika, 55, 422-424.
    • (1968) Biometrika , vol.55 , pp. 422-424
    • Mallows, C.L.1
  • 26
    • 10144251059 scopus 로고
    • Somatic mosaicism due to a prethymic mutation explains a high hprt mutant frequency outlier in a human population
    • Thomas, C.B., Burkhart-Schultz, K., Langlois, R.G., Tucker, J.D., Thompson, C.L. and Jones, I.M. (1994) Somatic mosaicism due to a prethymic mutation explains a high hprt mutant frequency outlier in a human population. Environ. Mol. Mutagen., 23 (Suppl. 23), 65.
    • (1994) Environ. Mol. Mutagen. , vol.23 , Issue.23 SUPPL. , pp. 65
    • Thomas, C.B.1    Burkhart-Schultz, K.2    Langlois, R.G.3    Tucker, J.D.4    Thompson, C.L.5    Jones, I.M.6
  • 27
    • 0028916130 scopus 로고
    • Mapping the end points of large deletions affecting the hprt locus in human peripheral blood cells and cell lines
    • Nelson, S.L., Jones, I.M., Fuscoe, J.C., Burkhart-Schultz, K. and Grosovsky, A.J. (1995) Mapping the end points of large deletions affecting the hprt locus in human peripheral blood cells and cell lines. Radiat. Res., 141, 2-10.
    • (1995) Radiat. Res. , vol.141 , pp. 2-10
    • Nelson, S.L.1    Jones, I.M.2    Fuscoe, J.C.3    Burkhart-Schultz, K.4    Grosovsky, A.J.5
  • 28
    • 0028083309 scopus 로고
    • The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP
    • Eads, J.C., Scapin, G., Xu, Y., Grubmeyer, C. and Sacchettini, J.C. (1994) The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP. Cell, 78, 325-334.
    • (1994) Cell , vol.78 , pp. 325-334
    • Eads, J.C.1    Scapin, G.2    Xu, Y.3    Grubmeyer, C.4    Sacchettini, J.C.5
  • 29
    • 0027034863 scopus 로고
    • Missense mutations and evolutionary conserved amino acids at the human hypoxanthine phosphoribosyl-transferase locus
    • Lambert, B., Marcus, S., Andersson, B., Hou, S-M., Steen, A.-M. and Hellgren, D. (1992) Missense mutations and evolutionary conserved amino acids at the human hypoxanthine phosphoribosyl-transferase locus. Pharmacogenetics, 2, 329-336.
    • (1992) Pharmacogenetics , vol.2 , pp. 329-336
    • Lambert, B.1    Marcus, S.2    Andersson, B.3    Hou, S.-M.4    Steen, A.-M.5    Hellgren, D.6
  • 30
    • 0026722138 scopus 로고
    • Enhanced hprt mutant frequency but no significant difference in mutation spectrum between a smoking and a non-smoking human population
    • Vrieling, H., Thijssen, J.C.P., Rossi, A.M., van Dam, F.J., Natarajan, A.T., Tates, A.D. and van Zeeland, A.A. (1992) Enhanced hprt mutant frequency but no significant difference in mutation spectrum between a smoking and a non-smoking human population. Carcinogenesis, 13, 1625-1631.
    • (1992) Carcinogenesis , vol.13 , pp. 1625-1631
    • Vrieling, H.1    Thijssen, J.C.P.2    Rossi, A.M.3    Van Dam, F.J.4    Natarajan, A.T.5    Tates, A.D.6    Van Zeeland, A.A.7
  • 31
    • 0025364861 scopus 로고
    • The mutational spectrum of single base-pair substitutions causing human genetic disease: Patterns and predictions
    • Cooper, D.N. and Krawczak, M. (1990) The mutational spectrum of single base-pair substitutions causing human genetic disease: patterns and predictions. Hum. Genet., 85, 55-74.
    • (1990) Hum. Genet. , vol.85 , pp. 55-74
    • Cooper, D.N.1    Krawczak, M.2
  • 32
    • 0027160625 scopus 로고
    • Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells
    • Wei, S.-J.C., Chang, R.L., Bhachech, N. et al. (1993) Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells. Cancer Res., 53, 3294-3301.
    • (1993) Cancer Res. , vol.53 , pp. 3294-3301
    • Wei, S.-J.C.1    Chang, R.L.2    Bhachech, N.3
  • 33
    • 0028812136 scopus 로고
    • Are base substitution and frameshift mutagenesis pathways interrelated? An analysis based upon studies of the frequencies and specificities of mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene
    • Rodriguez, H. and Loechler, E.L. (1995) Are base substitution and frameshift mutagenesis pathways interrelated? An analysis based upon studies of the frequencies and specificities of mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene. Mutat. Res., 326, 29-37.
    • (1995) Mutat. Res. , vol.326 , pp. 29-37
    • Rodriguez, H.1    Loechler, E.L.2
  • 35
    • 0025902273 scopus 로고
    • Endogenous mutagens and the causes of aging and cancer
    • Ames, B.N. and Gold, L.S. (1991) Endogenous mutagens and the causes of aging and cancer. Mutat. Res., 250, 3-16.
    • (1991) Mutat. Res. , vol.250 , pp. 3-16
    • Ames, B.N.1    Gold, L.S.2
  • 36
    • 0026592966 scopus 로고
    • 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G→T and A→C substitutions
    • Cheng, K.C., Cahill, D.S., Kasai, H., Nishimura, S. and Loeb, L.A. (1992) 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G→T and A→C substitutions. J. Biol. Chem., 267, 166-172.
    • (1992) J. Biol. Chem. , vol.267 , pp. 166-172
    • Cheng, K.C.1    Cahill, D.S.2    Kasai, H.3    Nishimura, S.4    Loeb, L.A.5
  • 37
    • 0028566564 scopus 로고
    • The fidelity of the human leading and lagging strand DNA replication apparatus with 8-oxodeoxyguanosine
    • Minnick, D.T., Pavlov, Y.I. and Kunkel, T.A. (1994) The fidelity of the human leading and lagging strand DNA replication apparatus with 8-oxodeoxyguanosine. Nucleic Acids Res., 22, 5658-5664.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5658-5664
    • Minnick, D.T.1    Pavlov, Y.I.2    Kunkel, T.A.3
  • 39
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt, M.S., Bennett, W.P., Hollstein, M. and Harris, C.C. (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54, 4855-4878.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 40
    • 0027153293 scopus 로고
    • Tandem double CC→TT mutations are produced by reactive oxygen species
    • Reid, T.M. and Loeb, L.A. (1993) Tandem double CC→TT mutations are produced by reactive oxygen species. Proc. Natl Acad. Sci. USA, 90, 3904-3907.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 3904-3907
    • Reid, T.M.1    Loeb, L.A.2
  • 41
    • 0028215974 scopus 로고
    • Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer
    • Tornaletti, S. and Pfeifer, G.P. (1994) Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer. Science, 263, 1436-1438.
    • (1994) Science , vol.263 , pp. 1436-1438
    • Tornaletti, S.1    Pfeifer, G.P.2
  • 42
    • 0025997527 scopus 로고
    • Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes
    • Bronstein, S.M., Cochrane, J.E., Craft, T.R., Swenberg, J.A. and Skopek, T.R. (1991) Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes. Cancer Res., 51, 5188-5197.
    • (1991) Cancer Res. , vol.51 , pp. 5188-5197
    • Bronstein, S.M.1    Cochrane, J.E.2    Craft, T.R.3    Swenberg, J.A.4    Skopek, T.R.5
  • 43
    • 0026707320 scopus 로고
    • Strand specificity for mutations induced by (+)-anti BPDE in the hprt gene in human T-lymphocytes
    • Andersson, B., Falt, S. and Lambert, B. (1992) Strand specificity for mutations induced by (+)-anti BPDE in the hprt gene in human T-lymphocytes. Mutat. Res., 269, 129-140.
    • (1992) Mutat. Res. , vol.269 , pp. 129-140
    • Andersson, B.1    Falt, S.2    Lambert, B.3
  • 44
    • 0026669733 scopus 로고
    • Mutations causing defective splicing in the human hprt gene
    • Andersson, B., Hou, S.-M. and Lambert, B. (1992) Mutations causing defective splicing in the human hprt gene. Environ. Mol. Mutagen., 20, 89-95.
    • (1992) Environ. Mol. Mutagen. , vol.20 , pp. 89-95
    • Andersson, B.1    Hou, S.-M.2    Lambert, B.3
  • 45
    • 0025152226 scopus 로고
    • Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutation induced by (±)-7b,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo-[a]pyrene in the coding region of the HPRT gene
    • Chen, R.-H., Maher, V.M. and McCormick, J.J. (1990) Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutation induced by (±)-7b,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo-[a]pyrene in the coding region of the HPRT gene. Proc. Natl Acad. Sci. USA, 87, 8680-8684.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 8680-8684
    • Chen, R.-H.1    Maher, V.M.2    McCormick, J.J.3
  • 46
    • 0025807132 scopus 로고
    • Lack of a cell cycle-dependent strand bias for mutations induced in the HPRT gene by (±)-7b,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in excision repair-deficient human cells
    • Chen, R.-H., Maher, V.M. and McCormick, J.J. (1991) Lack of a cell cycle-dependent strand bias for mutations induced in the HPRT gene by (±)-7b,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in excision repair-deficient human cells. Cancer Res., 51, 2587-2592.
    • (1991) Cancer Res. , vol.51 , pp. 2587-2592
    • Chen, R.-H.1    Maher, V.M.2    McCormick, J.J.3
  • 47
    • 0026062178 scopus 로고
    • Kinds and location of mutations induced by (±)-7b,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts
    • Yang, J.-L., Chen, R.-H., Maher, V.M. and McCormick, J.J. (1991) Kinds and location of mutations induced by (±)-7b,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts. Carcinogenesis, 12, 71-75.
    • (1991) Carcinogenesis , vol.12 , pp. 71-75
    • Yang, J.-L.1    Chen, R.-H.2    Maher, V.M.3    McCormick, J.J.4
  • 48
    • 0028564949 scopus 로고
    • Mismatch repair, genetic stability, and cancer
    • Modrich, P. (1994) Mismatch repair, genetic stability, and cancer. Science, 266, 1959-1960.
    • (1994) Science , vol.266 , pp. 1959-1960
    • Modrich, P.1
  • 49
    • 0028556806 scopus 로고
    • A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype
    • Aquilina, G., Hess, P., Branch, P., MacGeoch, C., Casciano, I., Karran, P. and Bignami, M. (1994) A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype. Proc. Natl Acad. Sci. USA, 91, 8905-8909.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 8905-8909
    • Aquilina, G.1    Hess, P.2    Branch, P.3    MacGeoch, C.4    Casciano, I.5    Karran, P.6    Bignami, M.7
  • 50
    • 0028603259 scopus 로고
    • Spontaneous mutations at aprt locus in a mammalian cell line defective in mismatch recognition
    • Hess, P., Aquilina, G., Dogliotti, E. and Bignami, M. (1994) Spontaneous mutations at aprt locus in a mammalian cell line defective in mismatch recognition. Somatic Cell Mol. Genet., 20, 409-421.
    • (1994) Somatic Cell Mol. Genet. , vol.20 , pp. 409-421
    • Hess, P.1    Aquilina, G.2    Dogliotti, E.3    Bignami, M.4
  • 51
    • 0027285855 scopus 로고
    • Molecular analysis of ethylene oxide-induced mutations at the HPRT locus in human diploid fibroblasts
    • Bastlova, T., Andersson, B., Lambert, B. and Kolman, A. (1993) Molecular analysis of ethylene oxide-induced mutations at the HPRT locus in human diploid fibroblasts. Mutat. Res., 287, 283-292.
    • (1993) Mutat. Res. , vol.287 , pp. 283-292
    • Bastlova, T.1    Andersson, B.2    Lambert, B.3    Kolman, A.4
  • 52
    • 0027181011 scopus 로고
    • Detection of DNA adducts at the DNA sequence level by ligation-mediated PCR
    • Pfeifer, G.P., Drouin, R. and Holmquist, G.P. (1993) Detection of DNA adducts at the DNA sequence level by ligation-mediated PCR. Mutat. Res., 288, 39-46.
    • (1993) Mutat. Res. , vol.288 , pp. 39-46
    • Pfeifer, G.P.1    Drouin, R.2    Holmquist, G.P.3
  • 53
    • 0026502151 scopus 로고
    • Molecular analysis of mutations affecting hprt mRNA splicing in human T-lymphocytes in vivo
    • Rossi, A.M., Tates, A.D., van Zeeland, A.A. and Vrieling, H. (1992) Molecular analysis of mutations affecting hprt mRNA splicing in human T-lymphocytes in vivo. Environ. Mol. Mutagen., 19, 7-13.
    • (1992) Environ. Mol. Mutagen. , vol.19 , pp. 7-13
    • Rossi, A.M.1    Tates, A.D.2    Van Zeeland, A.A.3    Vrieling, H.4
  • 54
    • 0027153307 scopus 로고
    • Analysis of germline and in vivo somatic mutations in the human adenine phosphoribosyltransferase gene: Mutational hot spots at the intron 4 splice donor site and at codon 87
    • Chen, J., Sahota, A., Martin, G.F., Hakoda, M., Kamatani, N., Stambrook, P.J. and Tischfield, J.A. (1993) Analysis of germline and in vivo somatic mutations in the human adenine phosphoribosyltransferase gene: Mutational hot spots at the intron 4 splice donor site and at codon 87. Mutat. Res., 287, 217-225.
    • (1993) Mutat. Res. , vol.287 , pp. 217-225
    • Chen, J.1    Sahota, A.2    Martin, G.F.3    Hakoda, M.4    Kamatani, N.5    Stambrook, P.J.6    Tischfield, J.A.7


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