-
1
-
-
0029841565
-
Antigen-specific targeting of CD28-mediated T cell co-stimulation using chimeric single-chain antibody variable fragment-CD28 receptors
-
Alvarez-Vallina L, and Hawkins RE (1996) Antigen-specific targeting of CD28-mediated T cell co-stimulation using chimeric single-chain antibody variable fragment-CD28 receptors. Eur J Immunol 26: 2304-2309
-
(1996)
Eur J Immunol
, vol.26
, pp. 2304-2309
-
-
Alvarez-Vallina, L.1
Hawkins, R.E.2
-
2
-
-
0000184190
-
Specific lysis of tumor cells by a natural-killer-like cell line transfected with chimeric receptor genes
-
Bach N, Waks T. Eshhar Z (1995) Specific lysis of tumor cells by a natural-killer-like cell line transfected with chimeric receptor genes. Tumor Targetting 1:203-209
-
(1995)
Tumor Targetting
, vol.1
, pp. 203-209
-
-
Bach, N.1
Waks, T.2
Eshhar, Z.3
-
3
-
-
0024435150
-
Expression of a hybrid immunoglobulin-T cell receptor protein in transgenic mice
-
Becker MLB, Near R. Mudgett-Hunter M, Margolies MN, Kubo RT, Kaye J, Hedrick SM (1989) Expression of a hybrid immunoglobulin-T cell receptor protein in transgenic mice. Cell 58: 911-921
-
(1989)
Cell
, vol.58
, pp. 911-921
-
-
Becker, M.L.B.1
Near, R.2
Mudgett-Hunter, M.3
Margolies, M.N.4
Kubo, R.T.5
Kaye, J.6
Hedrick, S.M.7
-
5
-
-
0024293979
-
Single chain antigen binding proteins
-
Bird RE, Hardman KD, Jacobson JW, Johnson S, Kaufman BM, Lee S-M, Lee T, Pope SH, Riordan GS, Whitlow M (1988). Single chain antigen binding proteins. Science 242:423-426.
-
(1988)
Science
, vol.242
, pp. 423-426
-
-
Bird, R.E.1
Hardman, K.D.2
Jacobson, J.W.3
Johnson, S.4
Kaufman, B.M.5
Lee, S.-M.6
Lee, T.7
Pope, S.H.8
Riordan, G.S.9
Whitlow, M.10
-
6
-
-
0028902765
-
Signals through T cell receptor-zeta chain alone are insufficient to prime resting T lymphocytes
-
Brocker T, Karjalainen K (1995) Signals through T cell receptor-zeta chain alone are insufficient to prime resting T lymphocytes. J Exp Med 181:1653-1659
-
(1995)
J Exp Med
, vol.181
, pp. 1653-1659
-
-
Brocker, T.1
Karjalainen, K.2
-
7
-
-
0030001675
-
Lymphocyte homing and homeostasis
-
11996
-
Butcher EC, Picker LJ (11996) Lymphocyte homing and homeostasis. Science 272:60-66
-
Science
, vol.272
, pp. 60-66
-
-
Butcher, E.C.1
Picker, L.J.2
-
8
-
-
0027471898
-
Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors
-
Eshhar Z, Waks T. Gross G, Schindler DG (1993) Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors. Proc Natl Acad Sci USA 90:720-724
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 720-724
-
-
Eshhar, Z.1
Waks, T.2
Gross, G.3
Schindler, D.G.4
-
9
-
-
0028875906
-
T-bodies: Chimeric, T-cell receptors with antibody-type specificity
-
Eshhar Z, Gross G, Waks T, Lustgarten J, Bach N, Ratner A, Treisman J. Schindler DG (1995) T-bodies: chimeric, T-cell receptors with antibody-type specificity. Methods companion to methods Enzymol 8:133-142
-
(1995)
Methods Companion to Methods Enzymol
, vol.8
, pp. 133-142
-
-
Eshhar, Z.1
Gross, G.2
Waks, T.3
Lustgarten, J.4
Bach, N.5
Ratner, A.6
Treisman, J.7
Schindler, D.G.8
-
10
-
-
0028097848
-
kat: A high-efficiency retroviraltransduction systemfor primary human T lymphocytes
-
Finer MH, Dull TJ, Qin L, Farson D, Roberts MR (1994) kat: a high-efficiency retroviraltransduction systemfor primary human T lymphocytes. Blood 83:43-50
-
(1994)
Blood
, vol.83
, pp. 43-50
-
-
Finer, M.H.1
Dull, T.J.2
Qin, L.3
Farson, D.4
Roberts, M.R.5
-
11
-
-
0030887137
-
Direct T cell activation by chimeric single chain-Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation
-
Fitzer-Attas CJ, Schindler DG, Waks T, Eshhar Z (1997) Direct T cell activation by chimeric single chain-Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation. J Biol Chem 272:8551-8557
-
(1997)
J Biol Chem
, vol.272
, pp. 8551-8557
-
-
Fitzer-Attas, C.J.1
Schindler, D.G.2
Waks, T.3
Eshhar, Z.4
-
12
-
-
4243638320
-
Harnessing Syk-family tyrosine kinases as signaling domains for chimeric scFv receptors: Optimal design for T cell activation
-
in press
-
Fitzer-Attas CJ, Schindler DG, Waks T, Eshhar Z (1997) Harnessing Syk-family tyrosine kinases as signaling domains for chimeric scFv receptors: optimal design for T cell activation. Immunology (in press)
-
(1997)
Immunology
-
-
Fitzer-Attas, C.J.1
Schindler, D.G.2
Waks, T.3
Eshhar, Z.4
-
13
-
-
0025324449
-
Chimeric immunoglobulin-T cell receptor proteins form functional receptors: Implications for T cell receptor complex formation and activation
-
Goverman J, Gomez SM, Segesman KD, Hunkapiller T, Laug WE, Hood L (1990) Chimeric immunoglobulin-T cell receptor proteins form functional receptors: implications for T cell receptor complex formation and activation. Cell 60:929-939
-
(1990)
Cell
, vol.60
, pp. 929-939
-
-
Goverman, J.1
Gomez, S.M.2
Segesman, K.D.3
Hunkapiller, T.4
Laug, W.E.5
Hood, L.6
-
14
-
-
0027076836
-
Endowing T cells with antibody specificity using chimeric T cell receptors
-
Gross G, Eshhar Z (1992) Endowing T cells with antibody specificity using chimeric T cell receptors. FASEB J 6:3370-3378
-
(1992)
FASEB J
, vol.6
, pp. 3370-3378
-
-
Gross, G.1
Eshhar, Z.2
-
15
-
-
0024580836
-
Generation of effector T cells expressing chimeric T cell receptors with antibody type specificity
-
Gross G, Gorochov G, Waks T, Eshhar Z (1989) Generation of effector T cells expressing chimeric T cell receptors with antibody type specificity. Trans Proc 21:127-130
-
(1989)
Trans Proc
, vol.21
, pp. 127-130
-
-
Gross, G.1
Gorochov, G.2
Waks, T.3
Eshhar, Z.4
-
16
-
-
0024834988
-
Expression of immunoglobulin/T cell receptor chimeric molecules as functional receptors with antibody-type specificity
-
Gross G, Waks T, Eshhar Z (1989) Expression of immunoglobulin/T cell receptor chimeric molecules as functional receptors with antibody-type specificity. Proc Natl Acad Sci USA 86: 10024-10028.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 10024-10028
-
-
Gross, G.1
Waks, T.2
Eshhar, Z.3
-
17
-
-
0028841826
-
Chimeric T cell receptors specific to a B lymphoma idiotype: A model for tumor immunotherapy
-
Gross G, Levy S, Levy R, Waks T, Eshhar Z (1995) Chimeric T cell receptors specific to a B lymphoma idiotype: A model for tumor immunotherapy. Biochem Soc Trans 23:1079-1082.
-
(1995)
Biochem Soc Trans
, vol.23
, pp. 1079-1082
-
-
Gross, G.1
Levy, S.2
Levy, R.3
Waks, T.4
Eshhar, Z.5
-
18
-
-
0004198722
-
Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single chain Fv analogue produced in Escherichia coli
-
Huston JS, Levinson D, Mudget-Hunter M, Tai M-S, Novotny J, Margolies MN, Ridge RJ, Bruccoleri RE, Haber E, Crea R, Oppermann H (1988) Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single chain Fv analogue produced in Escherichia coli. Proc Natl Acad Sci USA 85:5879-5884
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 5879-5884
-
-
Huston, J.S.1
Levinson, D.2
Mudget-Hunter, M.3
Tai, M.-S.4
Novotny, J.5
Margolies, M.N.6
Ridge, R.J.7
Bruccoleri, R.E.8
Haber, E.9
Crea, R.10
Oppermann, H.11
-
19
-
-
0027283443
-
Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor g chain
-
Hwu P, Shafer GE, Treisman J, Schindler DG, Gross G, Cowhead R, Rosenberg SA, Eshhar Z (1993) Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor g chain. J Exp Med 178:361-366
-
(1993)
J Exp Med
, vol.178
, pp. 361-366
-
-
Hwu, P.1
Shafer, G.E.2
Treisman, J.3
Schindler, D.G.4
Gross, G.5
Cowhead, R.6
Rosenberg, S.A.7
Eshhar, Z.8
-
20
-
-
0029134048
-
In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes
-
Hwu P, Yang JC, Cowherd R, Treisman J, Shafer GE, Eshhar Z, Rosenberg SA. (1995) In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes. Cancer Res 55:3369-3373
-
(1995)
Cancer Res
, vol.55
, pp. 3369-3373
-
-
Hwu, P.1
Yang, J.C.2
Cowherd, R.3
Treisman, J.4
Shafer, G.E.5
Eshhar, Z.6
Rosenberg, S.A.7
-
21
-
-
0001855136
-
Barriers to drug delivery in solid tumors
-
Jain RK (1994) Barriers to drug delivery in solid tumors. Sci Am 271:42-49
-
(1994)
Sci Am
, vol.271
, pp. 42-49
-
-
Jain, R.K.1
-
22
-
-
0023568155
-
Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions
-
Kuwana Y, Asakura Y, Utsunomiya N, Nakanishi M, Arata Y, Itoh S, Nagase F, Kurosawa Y (1987) Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions. Biochem Biophys Res Commun 149:960-968
-
(1987)
Biochem Biophys Res Commun
, vol.149
, pp. 960-968
-
-
Kuwana, Y.1
Asakura, Y.2
Utsunomiya, N.3
Nakanishi, M.4
Arata, Y.5
Itoh, S.6
Nagase, F.7
Kurosawa, Y.8
-
23
-
-
0028787631
-
Specific elimination of IgE production using T cell lines expressing chimeric T cell receptor genes
-
Lustgarten J, Eshhar Z (1995) Specific elimination of IgE production using T cell lines expressing chimeric T cell receptor genes. Eur J Immunol 25:2985-2991
-
(1995)
Eur J Immunol
, vol.25
, pp. 2985-2991
-
-
Lustgarten, J.1
Eshhar, Z.2
-
24
-
-
0027056895
-
Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice
-
Mizoguchi H, O'Shea JJ, Longo DL, Loeffler CM, McVicar DW, Ochoa AC (1992) Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice Science 258:1795-1798
-
(1992)
Science
, vol.258
, pp. 1795-1798
-
-
Mizoguchi, H.1
O'Shea, J.J.2
Longo, D.L.3
Loeffler, C.M.4
McVicar, D.W.5
Ochoa, A.C.6
-
25
-
-
0028879071
-
A spacer region between the single chain antibody and the CD3 ζ chain domain of chimeric T cell receptor components is required for efficient ligand binding and signaling activity
-
Moritz D, Groner B (1995) A spacer region between the single chain antibody and the CD3 ζ chain domain of chimeric T cell receptor components is required for efficient ligand binding and signaling activity. Gene Ther 2:539-546
-
(1995)
Gene Ther
, vol.2
, pp. 539-546
-
-
Moritz, D.1
Groner, B.2
-
26
-
-
0028328257
-
Cytotoxic T lymphocytes with a grafted recognition specificity for ErbB-2-expressing tumor cells
-
Moritz D, Wels W, Mattern J, Groner B (1994) Cytotoxic T lymphocytes with a grafted recognition specificity for ErbB-2-expressing tumor cells. Proc. Natl Acad Sci USA 91: 4318-4322
-
(1994)
Proc. Natl Acad Sci USA
, vol.91
, pp. 4318-4322
-
-
Moritz, D.1
Wels, W.2
Mattern, J.3
Groner, B.4
-
27
-
-
0024327899
-
Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy
-
Mueller DL, Jenkins MK, Schwartz RH (1989) Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. Annu Rev Immunol 7:445-480
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 445-480
-
-
Mueller, D.L.1
Jenkins, M.K.2
Schwartz, R.H.3
-
28
-
-
0027427548
-
Monoclonal antibodies in cancer therapy
-
Riethmuller G (1993) Monoclonal antibodies in cancer therapy. Curr Opin Immunol 5:732-739
-
(1993)
Curr Opin Immunol
, vol.5
, pp. 732-739
-
-
Riethmuller, G.1
-
29
-
-
0030927323
-
Making the T cell receptor go the distance: A topological view of T cell activation
-
Shaw SA, Dustin ML (1997) Making the T cell receptor go the distance: a topological view of T cell activation. Immunity 6: 361-369
-
(1997)
Immunity
, vol.6
, pp. 361-369
-
-
Shaw, S.A.1
Dustin, M.L.2
-
30
-
-
0027501259
-
Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors
-
Stancovski I, Schindler DG, Waks T, Yarden Y, Sela M, Eshhar Z (1993) Targeting of T lymphocytes to Neu/HER2-expressing cells using chimeric single chain Fv receptors. J Immunol 151: 6577-6582
-
(1993)
J Immunol
, vol.151
, pp. 6577-6582
-
-
Stancovski, I.1
Schindler, D.G.2
Waks, T.3
Yarden, Y.4
Sela, M.5
Eshhar, Z.6
-
31
-
-
0028983375
-
Chimeric ζ-receptors direct human natural killer (NK) effector function to permit killing of NK-resistant tumor cells and HIV-infected T lymphocytes
-
Tran A-C, Zhang D, Byrn R, Roberts MR (1995) Chimeric ζ-receptors direct human natural killer (NK) effector function to permit killing of NK-resistant tumor cells and HIV-infected T lymphocytes. J Immunol 155:1001-1009
-
(1995)
J Immunol
, vol.155
, pp. 1001-1009
-
-
Tran, A.-C.1
Zhang, D.2
Byrn, R.3
Roberts, M.R.4
-
32
-
-
0031172162
-
Serial triggering of TCRs: A basis for the sensitivity and specificity of antigen recognition
-
Valitutti S, Lanzavecchia A (1997) Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition. Immunol Today 18:299-304
-
(1997)
Immunol Today
, vol.18
, pp. 299-304
-
-
Valitutti, S.1
Lanzavecchia, A.2
-
33
-
-
0030161017
-
Second-generation adenovirus vectors
-
Wang Q, Finer MH (1996) Second-generation adenovirus vectors. Nat Med 2:714-716
-
(1996)
Nat Med
, vol.2
, pp. 714-716
-
-
Wang, Q.1
Finer, M.H.2
-
34
-
-
0030026798
-
Preventing abnormalities in signal transduction of T cells in cancer: The promise of cytokine gene therapy
-
Zier K, Gansbacher B, Salvadori S (1996) Preventing abnormalities in signal transduction of T cells in cancer: the promise of cytokine gene therapy. Immunol Today 17:39-45
-
(1996)
Immunol Today
, vol.17
, pp. 39-45
-
-
Zier, K.1
Gansbacher, B.2
Salvadori, S.3
|