메뉴 건너뛰기




Volumn 4, Issue 11, 1998, Pages 2825-2832

A single-chain immunotoxin against carcinoembryonic antigen that suppresses growth of colorectal carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; IMMUNOTOXIN; IODINE 125;

EID: 0031782883     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (22)

References (39)
  • 1
    • 0000696984 scopus 로고
    • Cancer markers
    • V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Philadelphia: Lippincott
    • Schwartz, M. K. Cancer markers. In: V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Cancer: Principles and Practice of Oncology, pp. 531-542. Philadelphia: Lippincott, 1993.
    • (1993) Cancer: Principles and Practice of Oncology , pp. 531-542
    • Schwartz, M.K.1
  • 4
    • 0021185738 scopus 로고
    • Effect of a monoclonal anti-carcinoembryonic antigen antibody-ricin A-chain conjugate on human carcinoembryonic antigen producing tumor cells
    • Watanabe, Y., Miyazaki, H., and Osawa, T. Effect of a monoclonal anti-carcinoembryonic antigen antibody-ricin A-chain conjugate on human carcinoembryonic antigen producing tumor cells. J. Pharmacobiodyn., 7: 593-603, 1984.
    • (1984) J. Pharmacobiodyn. , vol.7 , pp. 593-603
    • Watanabe, Y.1    Miyazaki, H.2    Osawa, T.3
  • 5
    • 0024402502 scopus 로고
    • A carcinoembryonic antigen-directed immunotoxin built by linking a monoclonal antibody to a hemolytic toxin
    • Avila, A. D., Mateo de Acosta, C., and Lage, A. A carcinoembryonic antigen-directed immunotoxin built by linking a monoclonal antibody to a hemolytic toxin. Int. J. Cancer, 43: 926-929, 1989.
    • (1989) Int. J. Cancer , vol.43 , pp. 926-929
    • Avila, A.D.1    Mateo De Acosta, C.2    Lage, A.3
  • 6
  • 7
    • 0026872063 scopus 로고
    • Thermostability and antitumor activity on colon cancer cell lines of monoclonal anti-CEA antibody-saporin immunotoxin
    • Manosroi, J., von Kleist, S., Manosroi, A., and Grunert, F. Thermostability and antitumor activity on colon cancer cell lines of monoclonal anti-CEA antibody-saporin immunotoxin. J. Korean Med. Sci., 7: 128-135, 1992.
    • (1992) J. Korean Med. Sci. , vol.7 , pp. 128-135
    • Manosroi, J.1    Von Kleist, S.2    Manosroi, A.3    Grunert, F.4
  • 8
    • 0028823794 scopus 로고
    • Growth suppression of human colorectal carcinoma in nude mice by monoclonal antibody C27-abrin A chain conjugate
    • Tsai, L-C., Chen, Y-L., Lee, C., Chen, H-M., Chang, Z-N., Hung, M-W., Chao, P-L., and Lin, J-Y. Growth suppression of human colorectal carcinoma in nude mice by monoclonal antibody C27-abrin A chain conjugate. Dis. Colon Rectum, 38: 1067-1074, 1995.
    • (1995) Dis. Colon Rectum , vol.38 , pp. 1067-1074
    • Tsai, L.-C.1    Chen, Y.-L.2    Lee, C.3    Chen, H.-M.4    Chang, Z.-N.5    Hung, M.-W.6    Chao, P.-L.7    Lin, J.-Y.8
  • 9
    • 0024349836 scopus 로고
    • A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin
    • Chaudhary, V. K., Queen, C., Junghans, R. P., Waldmann, T. A., FitzGerald, D. J., and Pastan, I. A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin. Nature (Lond.), 339: 394-397, 1989.
    • (1989) Nature (Lond.) , vol.339 , pp. 394-397
    • Chaudhary, V.K.1    Queen, C.2    Junghans, R.P.3    Waldmann, T.A.4    FitzGerald, D.J.5    Pastan, I.6
  • 10
    • 0042048435 scopus 로고
    • Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin
    • Batra, J. K., Jinno, Y., Chaudhary, V. K., Kondo, T., Willingham, M. C., FitzGerald, D. J., and Pastan, I. Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin. Proc. Natl. Acad. Sci. USA, 86: 8545-8549, 1989.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 8545-8549
    • Batra, J.K.1    Jinno, Y.2    Chaudhary, V.K.3    Kondo, T.4    Willingham, M.C.5    FitzGerald, D.J.6    Pastan, I.7
  • 11
    • 0026005994 scopus 로고
    • B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice
    • Brinkmann, U., Pai, L. H., FitzGerald, D. J., Willingham, M., and Pastan, I. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice. Proc. Natl. Acad. Sci. USA, 88: 8616-8620, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8616-8620
    • Brinkmann, U.1    Pai, L.H.2    FitzGerald, D.J.3    Willingham, M.4    Pastan, I.5
  • 12
    • 0039182817 scopus 로고    scopus 로고
    • Immunotoxin therapy
    • V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Philadelphia: Lippincott-Raven
    • Pai, L. H., and Pastan, I. Immunotoxin therapy. In: V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Cancer: Principles and Practice of Oncology, pp. 3045-3057. Philadelphia: Lippincott-Raven, 1997.
    • (1997) Cancer: Principles and Practice of Oncology , pp. 3045-3057
    • Pai, L.H.1    Pastan, I.2
  • 15
    • 0029050861 scopus 로고
    • The effect of transfection of the CEA gene on the metastatic behavior of the human colorectal cancer cell line MIP-101
    • Thomas, P., Gangopadhyay, A., Steele, G., Jr., Andrews, C., Nakazato, H., Oikawa, S., and Jessup, J. M. The effect of transfection of the CEA gene on the metastatic behavior of the human colorectal cancer cell line MIP-101. Cancer Lett., 92: 59-66, 1995.
    • (1995) Cancer Lett. , vol.92 , pp. 59-66
    • Thomas, P.1    Gangopadhyay, A.2    Steele Jr., G.3    Andrews, C.4    Nakazato, H.5    Oikawa, S.6    Jessup, J.M.7
  • 16
    • 14744300958 scopus 로고
    • Efficient production of a functional single-chain antidigoxin antibody via an engineered Bacillus subtilis expression-secretion system
    • Wu, X-C., Ng, S-C., Near, R. I., and Wong, S-L. Efficient production of a functional single-chain antidigoxin antibody via an engineered Bacillus subtilis expression-secretion system. Biotechnology, 11: 71-76, 1993.
    • (1993) Biotechnology , vol.11 , pp. 71-76
    • Wu, X.-C.1    Ng, S.-C.2    Near, R.I.3    Wong, S.-L.4
  • 17
    • 0028057249 scopus 로고
    • Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma
    • Kreitman, R. J., Bailon, P., Chaudhary, V. K., FitzGerald, D. J. P., and Pastan, I. Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma. Blood, 83: 426-434, 1994.
    • (1994) Blood , vol.83 , pp. 426-434
    • Kreitman, R.J.1    Bailon, P.2    Chaudhary, V.K.3    FitzGerald, D.J.P.4    Pastan, I.5
  • 18
    • 0026792807 scopus 로고
    • A method for increasing the yield of properly folded recombinant fusion proteins: Single-chain immunotoxins from renaturation of bacterial inclusion bodies
    • Buchner, J., Pastan, I., and Brinkmann, U. A method for increasing the yield of properly folded recombinant fusion proteins: single-chain immunotoxins from renaturation of bacterial inclusion bodies. Anal. Biochem., 205: 263-270, 1992.
    • (1992) Anal. Biochem. , vol.205 , pp. 263-270
    • Buchner, J.1    Pastan, I.2    Brinkmann, U.3
  • 19
    • 0025270366 scopus 로고
    • Anti-Tac-H, a humanized antibody to the interleukin 2 receptor with new features for immunotherapy in malignant and immune disorders
    • Junghans, R. P., Waldmann, T. A., Landolfi, N. F., Avdaloric, N. M., Schneider, W. P., and Queen, C. Anti-Tac-H, a humanized antibody to the interleukin 2 receptor with new features for immunotherapy in malignant and immune disorders. Cancer Res., 50: 1495-1502, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 1495-1502
    • Junghans, R.P.1    Waldmann, T.A.2    Landolfi, N.F.3    Avdaloric, N.M.4    Schneider, W.P.5    Queen, C.6
  • 22
    • 3643060409 scopus 로고    scopus 로고
    • Cruel antibody fictions! Cellular antigen enumeration by "saturation" binding, example CD3
    • in press
    • Junghans, R. P. Cruel antibody fictions! Cellular antigen enumeration by "saturation" binding, example CD3. Immunol. Today, in press, 1998.
    • (1998) Immunol. Today
    • Junghans, R.P.1
  • 23
    • 0028216376 scopus 로고
    • Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: Improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv
    • Reiter, Y., Brinkmann, U., Webber, K. O., Jung, S-H., Lee, B., and Pastan, I. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv. Protein Eng., 7: 697-704, 1994.
    • (1994) Protein Eng. , vol.7 , pp. 697-704
    • Reiter, Y.1    Brinkmann, U.2    Webber, K.O.3    Jung, S.-H.4    Lee, B.5    Pastan, I.6
  • 24
    • 0029144167 scopus 로고
    • Characterisation of B1(Fv)PE38 and B1(dsFv)PE38: Single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice
    • Benhar, I., and Pastan, I. Characterisation of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice. Clin. Cancer Res., 1: 1023-1029, 1995.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 1023-1029
    • Benhar, I.1    Pastan, I.2
  • 25
    • 0023951409 scopus 로고
    • Transcription of genes of the carcinoembryonic antigen family in malignant and nonmalignant human tissues
    • Cournoyer, D., Beauchemin, N., Boucher, D., Benchmol, S., Fuks, A., and Stanners, C. Transcription of genes of the carcinoembryonic antigen family in malignant and nonmalignant human tissues. Cancer Res., 48: 3153-3157, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 3153-3157
    • Cournoyer, D.1    Beauchemin, N.2    Boucher, D.3    Benchmol, S.4    Fuks, A.5    Stanners, C.6
  • 26
    • 0024517116 scopus 로고
    • Studies on the control of gene expression of the carcinoembryonic antigen family in human tissue
    • Boucher, D., Cournoyer, D., Stanners, C. P., and Fuks, A. Studies on the control of gene expression of the carcinoembryonic antigen family in human tissue. Cancer Res., 49: 847-852, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 847-852
    • Boucher, D.1    Cournoyer, D.2    Stanners, C.P.3    Fuks, A.4
  • 28
  • 29
    • 0028989908 scopus 로고
    • A single chain Fv derived from a filamentous phage library has distinct tumour targeting advantages over one derived from a hybridoma
    • Verhaar, M. J., Chester, K. A., Keep, P. A., Robson, L., Pedley, R. B., Boden, J. A., Hawkins, R. E., and Begent, R. H. J. A single chain Fv derived from a filamentous phage library has distinct tumour targeting advantages over one derived from a hybridoma. Int. J. Cancer, 61: 497-501, 1995.
    • (1995) Int. J. Cancer , vol.61 , pp. 497-501
    • Verhaar, M.J.1    Chester, K.A.2    Keep, P.A.3    Robson, L.4    Pedley, R.B.5    Boden, J.A.6    Hawkins, R.E.7    Begent, R.H.J.8
  • 30
    • 0025604134 scopus 로고
    • The effect of interteron treatment on 14 human colorectal cancer cell lines: Growth and carcinoembryonic antigen secretion in vitro
    • Toth, C. A., and Thomas, P. The effect of interteron treatment on 14 human colorectal cancer cell lines: growth and carcinoembryonic antigen secretion in vitro. J. Interferon Res., 10: 579-588, 1990.
    • (1990) J. Interferon Res. , vol.10 , pp. 579-588
    • Toth, C.A.1    Thomas, P.2
  • 31
    • 0025102956 scopus 로고
    • Regulation of carcinoembryonic antigen expression in different human colorectal tumor cells by interferon-γ
    • Guadagni, F., Witt, P. L., Robbins, P. F., Schlom, J., and Greiner, J. W. Regulation of carcinoembryonic antigen expression in different human colorectal tumor cells by interferon-γ. Cancer Res., 50: 6248-6255, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 6248-6255
    • Guadagni, F.1    Witt, P.L.2    Robbins, P.F.3    Schlom, J.4    Greiner, J.W.5
  • 32
    • 0029665818 scopus 로고    scopus 로고
    • Metabolism of Tac (IL2Rα): Physiology of cell surface shedding and renal elimination, and suppression of catabolism by antibody binding
    • Junghans, R. P., and Waldmann, T. A. Metabolism of Tac (IL2Rα): physiology of cell surface shedding and renal elimination, and suppression of catabolism by antibody binding. J. Exp. Med., 183: 1587-1602, 1996.
    • (1996) J. Exp. Med. , vol.183 , pp. 1587-1602
    • Junghans, R.P.1    Waldmann, T.A.2
  • 33
    • 0032539715 scopus 로고    scopus 로고
    • Impact of antigenemia on the bioactivity of infused anti-Tac antibody: Implication for dose selection in antibody immunotherapies
    • Junghans, R. P., Carrisquillo, J. A., Waldmann, T. A. Impact of antigenemia on the bioactivity of infused anti-Tac antibody: implication for dose selection in antibody immunotherapies. Proc. Natl. Acad. Sci. USA, 95: 1752-1757, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1752-1757
    • Junghans, R.P.1    Carrisquillo, J.A.2    Waldmann, T.A.3
  • 34
    • 0029383661 scopus 로고
    • Targeting Pseudomonas exotoxin to hematologic malignancies
    • Kreitman, R. J., and Pastan, I. Targeting Pseudomonas exotoxin to hematologic malignancies. Semin. Cancer Biol., 6: 297-306, 1995.
    • (1995) Semin. Cancer Biol. , vol.6 , pp. 297-306
    • Kreitman, R.J.1    Pastan, I.2
  • 35
    • 0025373376 scopus 로고
    • Murine monoclonal antibodies against carcinoembryonic antigen: Immunological, pharmacokinetic, and targeting properties in humans
    • Sharkey, R. M., Goldenberg, H., Lee, R. E., Ballance, C., Pawlyk, D., Varga, D., and Hansen, H. J. Murine monoclonal antibodies against carcinoembryonic antigen: immunological, pharmacokinetic, and targeting properties in humans. Cancer Res., 50: 2823-2831, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 2823-2831
    • Sharkey, R.M.1    Goldenberg, H.2    Lee, R.E.3    Ballance, C.4    Pawlyk, D.5    Varga, D.6    Hansen, H.J.7
  • 36
    • 0027613070 scopus 로고
    • Prediction of recurrence of gastrointestinal cancer from standpoint of biological malignancies: Tumor marker doubling time and its half life period line
    • Mai, M., and Takahashi, Y. Prediction of recurrence of gastrointestinal cancer from standpoint of biological malignancies: tumor marker doubling time and its half life period line. Hum. Cell, 6: 82-87, 1993.
    • (1993) Hum. Cell , vol.6 , pp. 82-87
    • Mai, M.1    Takahashi, Y.2
  • 37
    • 0027223468 scopus 로고
    • Cytotoxic activity of recombinant immunotoxins or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia
    • Baltimore
    • Kreitman, R. J., Chaudhary, V. K., Waldmann, T. A., Hanchard, B., Cranston, B., FitzGerald, D. J., and Pastan, I. Cytotoxic activity of recombinant immunotoxins or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia. Leukemia (Baltimore), 7: 553-562, 1993.
    • (1993) Leukemia , vol.7 , pp. 553-562
    • Kreitman, R.J.1    Chaudhary, V.K.2    Waldmann, T.A.3    Hanchard, B.4    Cranston, B.5    FitzGerald, D.J.6    Pastan, I.7
  • 38
    • 0013910824 scopus 로고
    • Insulin in blood and insulin antibodies
    • Berson, S. A., and Yalow, R. S. Insulin in blood and insulin antibodies. Am. J. Med., 40: 676-690, 1966.
    • (1966) Am. J. Med. , vol.40 , pp. 676-690
    • Berson, S.A.1    Yalow, R.S.2
  • 39
    • 0027239843 scopus 로고
    • Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
    • Finkelman, F. D., Madden, K. B., Morris, S. C., Holmes, J. M., Boiani, N., Katona, I. M., and Maliszewski, C. R. Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J. Immunol., 151: 1235-1244, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 1235-1244
    • Finkelman, F.D.1    Madden, K.B.2    Morris, S.C.3    Holmes, J.M.4    Boiani, N.5    Katona, I.M.6    Maliszewski, C.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.