Molecular recognition by cholesterol esterase of active site ligands: Structure-reactivity effects for inhibition by aryl carbamates and subsequent carbamylenzyme turnover

Biochemistry

Volumn 35, Issue 51, 1996, Pages 16723-16734

  Feaster, Shawn R ^a   Lee, Keun ^a   Baker, Nathan ^a   Hui, David Y ^b   Quinn, Daniel M ^a  

^a E11 SSH   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMATE INSECTICIDE; CHOLESTEROL ESTERASE;

ACYLATION; ANIMAL CELL; ARTICLE; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SPECIFICITY; LIGAND BINDING; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING SITES; CARBAMATES; CATALYSIS; CHOLESTEROL ESTERASE; ENZYME INHIBITORS; KINETICS; LIGANDS; PANCREAS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SWINE; THERMODYNAMICS;

ANIMALIA; MAMMALIA; SUIDAE; SUS SCROFA;

EID: 0030478552     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961677v     Document Type: Article

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