Structure-reactivity probes for active site shapes of cholesterol esterase by carbamate inhibitors

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1431, Issue 2, 1999, Pages 500-511

  Lin, Gialih ^a   Shieh, Chuen Tzwu ^a   Tsai, Yi Chin ^a   Hwang, Ching Ing ^a   Lu, Chun Ping ^a   Chen, Gan Hong ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Carbamate inhibitor; Cholesterol esterase

Indexed keywords

1,1' BI 2 N NAPHTHYL 2 BUTYLCARBAMATE 2' OL; 1,1' BI 2 NAPHTHYL 2 N BUTYLCARBAMATE 2' BUTYRATE; 1,1' BI 2 NAPHTHYL 2.2' DI N BUTYLCARBAMATE; 2,2' BIPHENYL 2 N BUTYLCARBAMATE 2' BUTYRATE; 2,2' BIPHENYL 2 N BUTYLCARBAMATE 2' OL; 2,2' BIPHENYL 2 N OCTADECYLCARBAMATE 2' N PHENYLCARBAMATE; 2,2' BIPHENYL 2 N OCTYLCARBAMATE 2' OL; 2,2' BIPHENYL DI N BUTYLCARBAMATE; 2.2' BIPHENYL 2 N OCTADECYLCARBAMATE 2' N OCTYLCARBAMATE; 4,4' BIPHENYL DI N BUTYLCARBAMATE; ALKYL GROUP; CARBAMIC ACID DERIVATIVE; CHOLESTEROL ESTERASE; ESTERASE INHIBITOR; GLYCERYL 1,2,3 TRI N BUTYLCARBAMATE; HYDROXYL GROUP; PANCREAS ENZYME; PHENYL GROUP; TRIFLUOROACETOPHENONE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; COVALENT BOND; DRUG CONFORMATION; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SWINE;

BINDING SITES; CARBAMATES; CHOLESTEROL ESTERASE; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; MODELS, CHEMICAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032946092     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(99)00073-4     Document Type: Article

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