Cx32 gene mutation in a chemically induced rat liver tumour

Carcinogenesis

Volumn 17, Issue 9, 1996, Pages 2077-2080

  Omori, Yasufumi ^a   Krutovskikh, Vladimir ^a   Mironov, Nicolai ^a   Tsuda, Hiroyuki ^b   Yamasaki, Hiroshi ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; DIETHYLNITROSAMINE; GAP JUNCTION PROTEIN; LIVER PROTEIN; LYSOPHOSPHATIDIC ACID; N ETHYL N (2 HYDROXYETHYL)NITROSAMINE; PHORBOL 13 ACETATE 12 MYRISTATE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL COMMUNICATION; CODON; CONTROLLED STUDY; DNA TRANSFECTION; DRUG INDUCED CANCER; GENE INDUCTION; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER TUMOR; PRIORITY JOURNAL;

EID: 0029813627     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.9.2077     Document Type: Article

References (27)

1. Paul, D.L. (1995) New functions for gap junctions. Curr. Opin. Cell Biol., 7, 665-672.
2. Bruzzone, R., White, T.W. and Paul, D.L. (1996) Connections with connexins: the molecular basis of direct intercellular signaling. Eur. J. Biochem., in press.
3. Yamasaki, H. (1990) Gap junctional intercellular communication and carcinogenesis. Carcinogenesis, 11, 1051-1058.
4. Krutovskikh, V.A., Oyamada, M. and Yamasaki, H. (1991) Sequential changes of gap-junctional intercellular communications during multistage rat liver carcinogenesis: direct measurement of communication in vivo. Carcinogenesis, 12, 1701-1706.
5. Fitzgerald, D.J., Mesnil, M., Oyamada, M., Tsuda, H., Ito, N. and Yamasaki, H. (1989) Changes in gap junction protein (connexin 32) gene expression during rat liver carcinogenesis. J. Cell Biochem., 41, 97-102.
6. Sakamoto, H., Oyamada, M., Enomoto, K. and Mori, M. (1992) Differential changes in expression of gap junction protein connexins 26 and 32 during hepatocarcinogenesis in rats. Jpn. J. Cancer Res., 83, 1210-1215.
7. Neveu, M.J., Hully, J.R., Paul, D.L. and Pitot, H.C. (1990) Reversible alteration in the expression of the gap junctional protein connexin 32 during tumor promotion in rat liver and its role during cell proliferation. Cancer Commun., 2, 21-31.
8. Krutovskikh, V., Mazzoleni, G., Mironov, N., Omori, Y., Aguelon, A.-M., Mesnil, M., Berger, R. Partensky, C. and Yamasaki, H. (1994) Altered homologous and heterologous gap-junctional intercellular communication in primary human liver tumours associated with aberrant protein localization hut not gene mutation of connexin 32. Int. J. Cancer, 56, 87-94.
9. Naus, C.C., Elisevich, K.M., Zhu, D., Belliveau, D.J. and Del Maestro, R.F. (1992) In vivo growth of C6 glioma cells transfected with connexin43 cDNA. Cancer Res., 52, 4208-4213.
10. Eghbali, B., Kessler, J.A., Reid, L.M., Roy, C. and Spray, D.C. (1991) Involvement of gap junctions in tumorigenesis: transfection of tumour cells with connexin 32 cDNA retards growth in vivo. Proc. Natl Acad. Sci. USA, 88, 10701-10705.
11. Rose, B., Mehta, P.P. and Loewenstein, W.R. (1993) Gap-junction protein gene suppresses tumorigenicity. Carcinogenesis, 14, 1073-1075.
12. Mesnil, M., Krutovskikh, V., Piccoli, C., Elfgang, C., Traub, O., Willecke, K. and Yamasaki, H. (1995) Negative growth control of HeLa cells by connexin genes: connexin species specificity. Cancer Res., 55, 629-639.
13. Kumar, N.M. and Gilula, N.B. (1986) Cloning and characterization of human and rat liver cDNAs coding for a gap junction protein. J. Cell Biol., 103, 767-776.
14. Miller, T., Dahl, G. and Werner, R. (1988) Structure of a gap junction gene; rat connexin-32. Biosci. Rep., 8, 455-464.
15. Musil, L.S., Cunningham, B.A., Dedelman, G.M. and Goodenough, D.A. (1990) Differential phosphorylation of the gpa junction protein connexin 43 in junctional communication-competent and -deficient cell lines. J. Cell Biol., 111, 2077-2088.
16. Enomoto, T., Martel, N., Kanno, Y. and Yamasaki, H. (1994) Inhibition of cell communication between BALB/c 3T3 cells by tumour promoters and protection by cAMP. J. Cell Physiol., 121, 323-333.
17. Mesnil, M., Asamoto, M., Piccoli, P. and Yamasaki, H. (1994) Possible molecular mechanisms of loss of homologous and heterologous gap junctional intercellular communication in rat liver epithelial cell lines. Cell Adhesion Commun., 2, 377-384.
18. Wiener, E.C. and Loewenstein, W.R. (1983) Correction of cell-cell communication detect by introduction of a protein kinase into mutant cells. Nature, 305, 433-135.
19. Hill, C.S., Oh, S.Y. Schmidt, S.A., Clark, H.K. and Murray, A.W. (1994) Lysophosphatidic acid inhibits gap-junctional communication and stimulates phosphorylation of connexin-43 in WB cells: possible involvement of the mitogen-activated protein kinase cascade. Biochem. J., 303, 475-479.
20. Mandelboim, O., Berke, G., Fridkin, M., Feldman, M., Eisenstein, M. and Eisenbach, L. (1994) CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma. Nature, 369, 67-71.
21. n DNA repeats and tumour-suppressor genes in human gastric cancer. Cancer Res., 54, 41-44.
22. Bergoffen, J. et al. (1993) Connexin mutation in X-linked Charcot-Marie-Tooth disease. Science, 262, 2039-2041.
23. Fairweather, N., Bell, C., Cochrane, S., Chelly, J., Wang, S., Mostacciulo, M.L., Monaco, A.P. and Haites, N.E. (1994) Mutations in the connexin 32 gene in X-linked dominant Charcot-Marie-Tooth disease (CMTX1). Hum. Mol. Genet., 3, 29-34.
24. Bone, L.J. et al. (1995) New connexin 32 mutations associated with X-linked Charcot-Marie-Tooth disease. Neurology, 45, 1863-1866.
25. Britz-Cunningham, S.H., Shah, M.M., Zuppan, C.W. and Fletcher, W.H. (1995) Mutations of the connexin 43 gap-junction gene in patients with heart malformations and defects of laterality. N. Engl. J. Med., 332, 1323, 1329.
26. Bruzzone, R., White, T.W., Scherer, S.S. Fischbeck, K.H. and Paul, D.L. (1994) Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease. Neuron, 13, 1253-1260.
27. Omori, Y., Mesnil, M. and Yamasaki, H. (1996) Connexin 32 mutations from X-linked Charcot-Marie-Tooth disease patients; functional defects and dominant-negative effects. Mol. Biol. Cell, in press.