Inhibition of interleukin-1β converting enzyme family proteases (caspases) reduces cold injury-induced brain trauma and DNA fragmentation in mice

Journal of Cerebral Blood Flow and Metabolism

Volumn 19, Issue 6, 1999, Pages 634-642

  Morita Fujimura, Yuiko ^a   Fujimura, Miki ^a   Kawase, Makoto ^a   Murakami, Kensuke ^a   Kim, Gyung Whan ^a   Chan, Pak H ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Caspase inhibitor; Cold injury; Neuronal apoptosis; Vasogenic edema

Indexed keywords

CASPASE INHIBITOR; CELL DNA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CASPASE; CYSTEINE PROTEINASE INHIBITOR; DNA FRAGMENT; PEPTIDE CHLOROMETHYL KETONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; CELL DEATH; COLD INJURY; CONTROLLED STUDY; DNA DEGRADATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEINASE INHIBITION; SIGNAL TRANSDUCTION; ANIMAL; BRAIN; COLD; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; NICK END LABELING; PATHOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; BLOTTING, WESTERN; BRAIN; BRAIN INJURIES; CASPASES; COLD; CYSTEINE PROTEINASE INHIBITORS; DNA FRAGMENTATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; IN SITU NICK-END LABELING; MALE; MICE;

EID: 0033238081     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199906000-00006     Document Type: Article

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