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Volumn 31, Issue 1, 1999, Pages 15-24

GAD65 and insulin B chain peptide (9-23) are not primary autoantigens in the type 1 diabetes syndrome of the BB rat

Author keywords

GAD65; GAD65 antibody; GAD65 p35; Immunization; Insulin B chain peptide (9 23); Tolerization; Type 1 diabetes

Indexed keywords

AUTOANTIGEN; GAMMA INTERFERON; GLUTAMATE DECARBOXYLASE; INSULIN; INTERLEUKIN 10; ISOENZYME; MESSENGER RNA; PROTEIN P35; ANTIBODY; AUTOANTIBODY; CYTOKINE; GLUTAMATE DECARBOXYLASE 65; INSULIN B (9 23); INSULIN B (9-23); PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

EID: 0033233474     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939908993855     Document Type: Article
Times cited : (13)

References (36)
  • 1
    • 0028672337 scopus 로고
    • Prevention of autoimmune diabetes in the BB rat by intrathymic islet transplantation at birth
    • E.H. Leiter and R.G. Gill, Prevention of autoimmune diabetes in the BB rat by intrathymic islet transplantation at birth. J. Endocrinol. Invest. 1994, 17: 595-599.
    • (1994) J. Endocrinol. Invest. , vol.17 , pp. 595-599
    • Leiter, E.H.1    Gill, R.G.2
  • 2
    • 0028151263 scopus 로고
    • Prevention of diabetes and insulitis by neonatal intrathymic islet administration in NOD mice
    • B. Charlton, E.-C. Taylor, R. Tisch and C.G. Fathtman. Prevention of diabetes and insulitis by neonatal intrathymic islet administration in NOD mice. J. Autoimmunity 1994, 7: 549-560.
    • (1994) J. Autoimmunity , vol.7 , pp. 549-560
    • Charlton, B.1    Taylor, E.-C.2    Tisch, R.3    Fathtman, C.G.4
  • 3
    • 0028026652 scopus 로고
    • Insulin-dependent diabetes mellitus as an autoimmune disease
    • J.F. Bach. Insulin-dependent diabetes mellitus as an autoimmune disease. Endocr. Rev. 1994, 15: 516-542.
    • (1994) Endocr. Rev. , vol.15 , pp. 516-542
    • Bach, J.F.1
  • 4
    • 0013674115 scopus 로고    scopus 로고
    • Immune surveillance: Paraneoplastic or environmental triggers of autoimmunity
    • Å. Lernmark. Immune surveillance: Paraneoplastic or environmental triggers of autoimmunity. Crit. Rev. Immunol. 1997, 17: 437-447.
    • (1997) Crit. Rev. Immunol. , vol.17 , pp. 437-447
    • Lernmark, A.1
  • 6
    • 0031252267 scopus 로고    scopus 로고
    • Autoantibodies to IA-2 and IA-2 beta in insulin-dependent diabetes mellitus recognize conformational epitopes - Location of the 37-and 40-kDa fragments determined
    • H. Xie, B.W. Zhang, Y. Matsumoto, Q. Li, A.L. Notkins and M.S. Lan. Autoantibodies to IA-2 and IA-2 beta in insulin-dependent diabetes mellitus recognize conformational epitopes - Location of the 37-and 40-kDa fragments determined. J. Immunol. 1997, 159: 3662-3667.
    • (1997) J. Immunol. , vol.159 , pp. 3662-3667
    • Xie, H.1    Zhang, B.W.2    Matsumoto, Y.3    Li, Q.4    Notkins, A.L.5    Lan, M.S.6
  • 7
    • 0029977765 scopus 로고    scopus 로고
    • Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD(65) and IA2 marks the early phases of autoimmune response in type 1 diabetes
    • H.J. Aanstoot, S.M. Kang, J. Kim, L.A. Lindsay, U. Roll, M. Knip et al. Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD(65) and IA2 marks the early phases of autoimmune response in type 1 diabetes. J. Clin. Invest. 1996, 97: 2772-2783.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2772-2783
    • Aanstoot, H.J.1    Kang, S.M.2    Kim, J.3    Lindsay, L.A.4    Roll, U.5    Knip, M.6
  • 8
    • 0028140001 scopus 로고
    • Potential autoantigens in IDDM. Expression of carboxypeptidase-H and insulin but not glutamate decarboxylase on the beta-cell surface
    • M. Aguilar-Diosdado, D. Parkinson, J. Corbett, G. Kwon, C.A. Marshall, R.L. Gingerich et al. Potential autoantigens in IDDM. Expression of carboxypeptidase-H and insulin but not glutamate decarboxylase on the beta-cell surface. Diabetes 1994, 43: 418-425.
    • (1994) Diabetes , vol.43 , pp. 418-425
    • Aguilar-Diosdado, M.1    Parkinson, D.2    Corbett, J.3    Kwon, G.4    Marshall, C.A.5    Gingerich, R.L.6
  • 9
    • 0028047441 scopus 로고
    • Islet-specific T-cell clones from the NOD mouse respond to beta-granule antigen
    • B. Bergman and K. Haskins. Islet-specific T-cell clones from the NOD mouse respond to beta-granule antigen. Diabetes 1994, 43: 197-203.
    • (1994) Diabetes , vol.43 , pp. 197-203
    • Bergman, B.1    Haskins, K.2
  • 10
    • 0028603421 scopus 로고
    • Neonatal tolerization with glutamic acid decarboxylase but not with bovine serum albumin delays the onset of diabetes in NOD mice
    • J.S. Petersen, A.E. Karlsen, H. Markholst, A. Worsaae, T. Dyrberg and B. Michelsen. Neonatal tolerization with glutamic acid decarboxylase but not with bovine serum albumin delays the onset of diabetes in NOD mice. Diabetes 1994, 43: 1478-1484.
    • (1994) Diabetes , vol.43 , pp. 1478-1484
    • Petersen, J.S.1    Karlsen, A.E.2    Markholst, H.3    Worsaae, A.4    Dyrberg, T.5    Michelsen, B.6
  • 11
    • 0031831753 scopus 로고    scopus 로고
    • Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice
    • R. Tisch, R.S. Liblau, X.D. Yang, P. Liblau and H.O. McDevitt. Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice. Diabetes 1998, 47: 894-899.
    • (1998) Diabetes , vol.47 , pp. 894-899
    • Tisch, R.1    Liblau, R.S.2    Yang, X.D.3    Liblau, P.4    McDevitt, H.O.5
  • 12
    • 0030069688 scopus 로고    scopus 로고
    • Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B (9-23)
    • D. Daniel and D.R. Wegmann. Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B (9-23). PNAS USA 1996, 93: 956-960.
    • (1996) PNAS USA , vol.93 , pp. 956-960
    • Daniel, D.1    Wegmann, D.R.2
  • 15
    • 0025890960 scopus 로고
    • Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB Wor rats
    • P.A. Gottlieb, E.S. Handler, M.C. Appel, D.L. Greiner, J.P. Mordes and A.A. Rossini. Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB Wor rats. Diabetologia 1991, 34: 296-300.
    • (1991) Diabetologia , vol.34 , pp. 296-300
    • Gottlieb, P.A.1    Handler, E.S.2    Appel, M.C.3    Greiner, D.L.4    Mordes, J.P.5    Rossini, A.A.6
  • 16
    • 0030871949 scopus 로고    scopus 로고
    • The lymphopenia (lyp) gene controls the intrathymic cytokine ratio in congenic BioBreeding rats
    • S. Bieg, C. Moller, T. Olsson and Å. Lernmark. The lymphopenia (lyp) gene controls the intrathymic cytokine ratio in congenic BioBreeding rats. Diabetologia 1997, 40: 786-792.
    • (1997) Diabetologia , vol.40 , pp. 786-792
    • Bieg, S.1    Moller, C.2    Olsson, T.3    Lernmark, A.4
  • 17
    • 0026722885 scopus 로고
    • Increased specificity and sensitivity of insulin antibody measurements in autoimmune thyroid disease and type I diabetes
    • M.J. Hegewald, S.L. Schoenfeld, D.K. McCulloch, C.J. Greenbaum, L.J. Klaff and J.P. Palmer. Increased specificity and sensitivity of insulin antibody measurements in autoimmune thyroid disease and type I diabetes. J. Immunol. Meth. 1992, 154: 61-68.
    • (1992) J. Immunol. Meth. , vol.154 , pp. 61-68
    • Hegewald, M.J.1    Schoenfeld, S.L.2    McCulloch, D.K.3    Greenbaum, C.J.4    Klaff, L.J.5    Palmer, J.P.6
  • 18
    • 0025340804 scopus 로고
    • Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-yr follow-up of the Seattle Family Study
    • D.K. McCulloch, L.J. Klaff, S.E. Kahn, S.L. Schoenfeld, C.J. Greenbaum, R.S Mauseth et al. Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-yr follow-up of the Seattle Family Study. Diabetes 1990, 39: 549-556.
    • (1990) Diabetes , vol.39 , pp. 549-556
    • McCulloch, D.K.1    Klaff, L.J.2    Kahn, S.E.3    Schoenfeld, S.L.4    Greenbaum, C.J.5    Mauseth, R.S.6
  • 20
    • 0028258006 scopus 로고
    • A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM
    • C.E. Grubin, T. Daniels, B. Toivola, M. Landin-Olsson, W. A. Hagopian, L. Li et al. A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM. Diabetologia 1994, 37: 344-350.
    • (1994) Diabetologia , vol.37 , pp. 344-350
    • Grubin, C.E.1    Daniels, T.2    Toivola, B.3    Landin-Olsson, M.4    Hagopian, W.A.5    Li, L.6
  • 22
    • 0025936419 scopus 로고
    • Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent mellitus
    • B.K. Michelsen, J.S. Petersen, E. Boel, A. Møldrup, T. Dyrberg and O.D. Madsen. Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent mellitus. PNAS USA 1991, 88: 8754-8758.
    • (1991) PNAS USA , vol.88 , pp. 8754-8758
    • Michelsen, B.K.1    Petersen, J.S.2    Boel, E.3    Møldrup, A.4    Dyrberg, T.5    Madsen, O.D.6
  • 23
    • 0029793724 scopus 로고    scopus 로고
    • Diagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantibodies in childhood IDDM
    • A. Falorni, M. Ackefors, C. Carlberg, T. Daniels, B. Persson, J. Robertson et al. Diagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantibodies in childhood IDDM. Diabetologia 1996, 39: 1091-1098.
    • (1996) Diabetologia , vol.39 , pp. 1091-1098
    • Falorni, A.1    Ackefors, M.2    Carlberg, C.3    Daniels, T.4    Persson, B.5    Robertson, J.6
  • 24
    • 0030731920 scopus 로고    scopus 로고
    • Retardation or acceleration of diabetes in NOD/Lt mice mediated by intrathymic administration of candidate beta cell antigens
    • M. Cetkovic-Cvrlje, I.C. Gerling, A. Muir, M.A. Elliot, E.H. Leiter. Retardation or acceleration of diabetes in NOD/Lt mice mediated by intrathymic administration of candidate beta cell antigens. Diabetes 1997, 46: 1975-1982.
    • (1997) Diabetes , vol.46 , pp. 1975-1982
    • Cetkovic-Cvrlje, M.1    Gerling, I.C.2    Muir, A.3    Elliot, M.A.4    Leiter, E.H.5
  • 25
    • 0028219777 scopus 로고
    • Autoantibodies to glutamate decarboxylase detected in diabetes-prone BB/OK rats do not distinguish onset of diabetes
    • M. Ziegler, M. Schlosser, J. Hamann, P. Vieregge, F. Luhder, I. Kloting et al. Autoantibodies to glutamate decarboxylase detected in diabetes-prone BB/OK rats do not distinguish onset of diabetes. Exp. Clin. Endocrinol. 1994, 102: 98-103.
    • (1994) Exp. Clin. Endocrinol. , vol.102 , pp. 98-103
    • Ziegler, M.1    Schlosser, M.2    Hamann, J.3    Vieregge, P.4    Luhder, F.5    Kloting, I.6
  • 26
    • 0020527178 scopus 로고
    • Identification of profound peripheral T lymphocyte immunodeficiencies in the spontaneously diabetic BB rat
    • M.E. Elder and N.K. Maclaren. Identification of profound peripheral T lymphocyte immunodeficiencies in the spontaneously diabetic BB rat. J. Immunol. 1983, 130: 1723-1731.
    • (1983) J. Immunol. , vol.130 , pp. 1723-1731
    • Elder, M.E.1    Maclaren, N.K.2
  • 27
    • 0030880922 scopus 로고    scopus 로고
    • The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice
    • D.M. Cataldo and G.A. Van Nast. The adjuvant MF59 increases the immunogenicity and protective efficacy of subunit influenza vaccine in mice. Vaccine 1997, 15: 1710-1715.
    • (1997) Vaccine , vol.15 , pp. 1710-1715
    • Cataldo, D.M.1    Van Nast, G.A.2
  • 28
    • 0030976101 scopus 로고    scopus 로고
    • MF59 adjuvant enhances antibody responses of infant baboons immunized with Haemophilus influenzae type b and Neisseria meningitidis group C oligosaccharide-CRM197 conjugate vaccine
    • D.M. Granoff, Y.E. McHugh, H.V. Raff, A.S. Mokatrin and G.A. Van Nest. MF59 adjuvant enhances antibody responses of infant baboons immunized with Haemophilus influenzae type b and Neisseria meningitidis group C oligosaccharide-CRM197 conjugate vaccine. Infect. Immun. 1997, 65: 1710-1715.
    • (1997) Infect. Immun. , vol.65 , pp. 1710-1715
    • Granoff, D.M.1    McHugh, Y.E.2    Raff, H.V.3    Mokatrin, A.S.4    Van Nest, G.A.5
  • 29
    • 0030012890 scopus 로고    scopus 로고
    • MF59 adjuvant enhances the immunogenicity of influenza vaccine in both young and old mice
    • D.A. Higgins, J.R. Carlson and G.A. VanNest. MF59 adjuvant enhances the immunogenicity of influenza vaccine in both young and old mice. Vaccine 1996, 14: 478-484.
    • (1996) Vaccine , vol.14 , pp. 478-484
    • Higgins, D.A.1    Carlson, J.R.2    VanNest, G.A.3
  • 30
    • 0028232762 scopus 로고
    • 2-terminal epitope in the autoantigen GAD65, distinguish Stiff-Man Syndrome from insulin-dependent diabetes mellitus
    • 2-terminal epitope in the autoantigen GAD65, distinguish Stiff-Man Syndrome from insulin-dependent diabetes mellitus. J. Exp. Med. 1994, 180: 595-606.
    • (1994) J. Exp. Med. , vol.180 , pp. 595-606
    • Kim, J.1    Namchuck, M.2    Bugawan, T.3    Fu, Q.4    Jaffe, M.5    Shi, Y.6
  • 31
    • 0029991807 scopus 로고    scopus 로고
    • Cellular immune response to diverse islet cell antigens in IDDM
    • B.I. Durinovic, M. Hummel and A.G. Ziegler. Cellular immune response to diverse islet cell antigens in IDDM. Diabetes 1996, 45: 795-800.
    • (1996) Diabetes , vol.45 , pp. 795-800
    • Durinovic, B.I.1    Hummel, M.2    Ziegler, A.G.3
  • 32
    • 0027176158 scopus 로고
    • Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes
    • L.C. Harrison, M.C. Honeyman, H.J. DeAizpurua, R.S. Schmidli, P.G. Colman, B.D. Tait et al. Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. Lancet 1993, 341: 1365-1369.
    • (1993) Lancet , vol.341 , pp. 1365-1369
    • Harrison, L.C.1    Honeyman, M.C.2    DeAizpurua, H.J.3    Schmidli, R.S.4    Colman, P.G.5    Tait, B.D.6
  • 33
    • 0031127957 scopus 로고    scopus 로고
    • High T cell responses to the glutamic acid decarboxylase (GAD) isoform 67 reflect a hyperimmune state that precedes the onset of insulin-dependent diabetes
    • M.C. Honeyman, N. Stone, H.J. DeAizpurua, M.J. Rowley and L.C. Harrison. High T cell responses to the glutamic acid decarboxylase (GAD) isoform 67 reflect a hyperimmune state that precedes the onset of insulin-dependent diabetes. J. Autoimmunity 1997, 10: 165-173.
    • (1997) J. Autoimmunity , vol.10 , pp. 165-173
    • Honeyman, M.C.1    Stone, N.2    DeAizpurua, H.J.3    Rowley, M.J.4    Harrison, L.C.5
  • 34
    • 0030175582 scopus 로고    scopus 로고
    • Relation between cellular and humoral immunity to islet cell antigens in type 1 diabetes
    • M. Hummel, I. Durinovic-Bello and A.G. Ziegler. Relation between cellular and humoral immunity to islet cell antigens in type 1 diabetes. J. Autoimmunity 1996, 9: 427-430.
    • (1996) J. Autoimmunity , vol.9 , pp. 427-430
    • Hummel, M.1    Durinovic-Bello, I.2    Ziegler, A.G.3
  • 35
    • 0027230077 scopus 로고
    • A multiplicity of protein antigens in subcellular fractions of rat insulinoma tissue are able to stimulate T cells obtained from non-obese diabetic mice
    • S. Bieg, E.M. Bailyes, N. Yassin, J. Amann, L. Herberg, A.M. McGregor et al. A multiplicity of protein antigens in subcellular fractions of rat insulinoma tissue are able to stimulate T cells obtained from non-obese diabetic mice. Diabetologia 1993, 36: 385-390.
    • (1993) Diabetologia , vol.36 , pp. 385-390
    • Bieg, S.1    Bailyes, E.M.2    Yassin, N.3    Amann, J.4    Herberg, L.5    McGregor, A.M.6
  • 36
    • 0030589224 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins
    • B.M. Brooks-Worrell, G.A. Starkebaum, C. Greenbaum and J.P. Palmer. Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins. J. Immunol. 1996, 157: 5668-5674.
    • (1996) J. Immunol. , vol.157 , pp. 5668-5674
    • Brooks-Worrell, B.M.1    Starkebaum, G.A.2    Greenbaum, C.3    Palmer, J.P.4


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