Negative regulation of α2-adrenergic receptor-mediated G(i) signalling by a novel pathway

Biochemical Journal

Volumn 343, Issue 1, 1999, Pages 77-85

  Takesono, Aya ^a   Zahner, Joe ^b   Blumer, Kendall J ^c   Nagao, Taku ^a   Kurose, Hitoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SAINT LOUIS UNIVERSITY   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenylate cyclase; Cholera toxin; Protein kinase C; Regulators of G protein signalling

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CHOLERA TOXIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLOHEXIMIDE; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PRIMER DNA;

ANIMAL CELL; ARTICLE; CHO CELL; CYTOSOL; FIBROBLAST; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL; ENZYME ACTIVATION; HAMSTER; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; RAT;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

ANIMALS; BASE SEQUENCE; CHO CELLS; CHOLERA TOXIN; CRICETINAE; DNA PRIMERS; ENZYME ACTIVATION; GTP-BINDING PROTEINS; PROTEIN BINDING; PROTEIN KINASE C; RATS; RECEPTORS, ADRENERGIC, ALPHA-2; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE;

EID: 0033215214     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3430077     Document Type: Article

References (46)

1. Guderman, T., Schöneberg, T. and Schultz, G. (1997) Annu. Rev. Neurosci. 20, 399-427
2. Premont, R. T., Inglese, J. and Lefkowitz, R. J. (1995) FASEB J. 9, 175-182
3. Krupnick, J. G. and Benovic, J. L (1998) Annu. Rev. Pharmacol. Toxicol. 38, 289-319
4. Attramadal, H., Arriza, J. L., Aoki, C., Dawson, T. M., Codina, J., Kwatra, M. M., Snyder, S. H., Caron, M. G. and Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 17882-17890
5. Ferguson, S. S. G., Downey, III, W. E., Colapietro, A.-M., Barak, L.S., Ménard, L. and Caron, M. G. (1996) Science 271, 363-366
6. Goodman, Jr., O. B., Krupnick, J. G., Santini, F., Gurevich, V. V., Penn, R. B., Gagnon, A. W., Keen, J. H. and Benovic, J. L. (1996) Nature (London) 383, 447-450
7. Sunahara, R. K., Dessauer, C. W. and Gilman, A. G. (1996) Annu. Rev. Pharmacol. Toxicol. 36, 461-480
8. Dohlman, H. G. and Thorner, J. (1997) J. Biol. Chem. 272, 3871-3874
9. Berman, D. M. and Gilman, A. G. (1998) J. Biol. Chem. 273, 1269-1272
10. Watson, N., Linder, M. E., Druey, K. M., Kehrl, J. H. and Blumer, K. J. (1996) Nature (London) 383, 172-175
11. Hunt, T. W., Fields, T. A., Casey, P. J. and Peralta, E. G. (1996) Nature (London) 383, 175-177
12. Druey, K. M., Blumer, K. J., Kang, V. H. and Kehrl, J. H. (1996) Nature (London) 379, 742-746
13. Huang, C., Hepler, J. R, Gilman, A. G. and Mumby, S. M. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 6159-6163
14. Yan, Y., Chi, P. P. and Bourne, H. R. (1997) J. Biol. Chem. 272, 11924-11927
15. Heximer, S. P., Watson, N., Linder, M. E., Blumer, K. J. and Hepler, J. R. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 14389-14393
16. Aantaa, R., Marjamaki, A. and Scheinin, M. (1995) Ann. Med. 27, 439-449
17. Jansso'n, C. C., Savola, J.-M. and Åkerman, K. E. O. (1994) Biochem. Biophys. Res. Commun. 199, 869-875
18. Convents, A., De Backer, J.-P., André, C. and Vauquelin, G. (1989) Biochem. J. 262, 245-251
19. Kurose, H. and Lefkowitz, R. J. (1994) J. Biol. Chem. 269, 10093-10099
20. Jewell-Motz, E. A. and Liggett, S. B. (1996) J. Biol. Chem. 271, 18082-18087
21. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275
22. Tsuga, H., Kameyama, K., Haga, T., Honma, T., Lameh, J. and Sadee, W. (1998) J. Biol. Chem. 273, 5323-5330
23. Salomon, Y., Londos, C. and Rodbell, M. (1974) Anal. Biochem. 58, 541-548
24. Kikkawa, H., Isogaya, M., Nagao, T. and Kurose, H. (1998) Mol. Pharmacol. 53, 128-134
25. Heximer, S. P., Cristillo, A. D. and Forsdyke, D. R. (1997) DNA Cell Biol. 16, 589-598
26. Eason, M. G., Kurose, H., Holt, B. D., Raymond, J. R. and Liggett, S. B. (1992) J. Biol. Chem. 267, 15795-15801
27. Hepler, J. R., Berman, D. M., Gilman, A. G. and Kozasa, T. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 428-432
28. Kozasa, T., Jiang, X., Hart, M. J., Sternweis, P. M., Singer, W.D., Gilman, A. G., Bollag, G. and Sternweis, P. C. (1998) Science 280, 2109-2111
29. Koelle, M. R. and Horvitz, H. R. (1996) Cell 84, 115-125
30. Bouvier, M., Guilbault, N. and Bonin, H. (1991) FEBS Lett. 279, 243-248
31. Mende, U., Kagen, A., Cohen, A., Aramburu, J., Schoen, F. J. and Neer, E. J. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 13894-13898
32. Pfeifer, A., Nürnberg, B., Kamm, S., Uhde, M., Schultz, G., Ruth, P. and Hofmann, F. (1995) J. Biol. Chem. 270, 9052-9059
33. Parruti, G., Peracchia, F., Sallese, M., Ambrosini, G., Masini, M., Rotilio, D. and De Blasi, A. (1993) J. Biol. Chem. 268, 9753-9761
34. Iacovelli, L., Franchetti, R., Masini, M. and De Blasi, A. (1996) Mol. Endocrinol. 10, 1138-1146
35. Pippig, S., Andexinger, S., Daniel, K., Puzicha, M., Caron, M.G., Lefkowitz, R. J. and Lohse, M. J. (1993) J. Biol. Chem. 268, 3201-3208
36. Spence, S., Rena, G., Sullivan, M., Erdogan, S. and Houslay, M.D. (1997) Biochem. J. 321, 157-163
37. Tang, W.-J. and Hurley, J. H. (1998) Mol. Pharmacol. 54, 231-240
38. Klein, U., Ramirez, M. T., Kobilka, B. K. and von Zastrow, M. (1997) J. Biol. Chem. 272, 19099-19102
39. Prezeau, L., Richman, J. G., Edwards, S. W. and Limbird, L. E. (1999) J. Biol. Chem. 274, 13462-13469
40. Neill, J. D., Duck, L. W., Sellers, J. C., Musgrove, L. C., Scheschonka, A., Druey, K. M. and Kehrl, J. H. (1997) Endocrinology (Baltimore) 138, 843-846
41. Siderovski, D. P., Hessel, A., Chung, S., Mak, T. W. and Tyers, M. (1996) Curr. Biol. 6, 211-212
42. Doupnik, C. A., Davidson, N., Lester, H. A. and Kofuji, P. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 10461-10466
43. Chen, C., Zheng, B., Han, J. and Lin, S.-C. (1997) J. Biol. Chem. 272, 8679-8685
44. Ingi, T., Krumins, A. M., Chidiac, P., Brothers, G. M., Chung, S., Snow, B. E., Barnes, C. A., Lanahan, A. A., Siderovski, D. P., Ross, E. M., Gilman, A. G. and Worley, P. F. (1998) J. Neurosci. 18, 7178-7188
45. Chatterjee, T., Eapen, A. K. and Fisher, R. A. (1997) J. Biol. Chem. 272, 15481-15487
46. Srinivasa, S. P., Bernstein, L. S., Blumer, K. J. and Linder, M. E. (1998) Proc. Natl. Acad. Sci. USA 95, 5584-5589