The gain-of-function Arabidopsis acd6 mutant reveals novel regulation and function of the salicylic acid signaling pathway in controlling cell death, defenses, and cell growth

Plant Cell

Volumn 11, Issue 9, 1999, Pages 1695-1708

  Rate, Debra N ^a   Cuenca, James V ^b   Bowman, Grant R ^b   Guttman, David S ^b   Greenberg, Jean T ^b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; ARABIDOPSIS; BACTERIA (MICROORGANISMS); PSEUDOMONAS; PSEUDOMONAS SYRINGAE;

EID: 0033197621     PISSN: 10404651     EISSN: None     Source Type: Journal    
DOI: 10.1105/tpc.11.9.1695     Document Type: Article

References (44)

1. Ahuja, M.R. (1998). Genetic tumors in Nicotiana and other plants. Q. Rev. Biol. 73, 439-462.
2. Baker, B., Zambryski, P., Staskawicz, B., and Dinesh-Kumar, S.P. (1997). Signaling in plant-microbe interactions. Science 276, 726-733.
3. Bender, C.L., Palmer, D.A., Penaloza-Vazquez, A., Rangaswamy, V., and Ullrich, M. (1998). Biosynthesis and regulation of coronatine, a non-host-specific phytotoxin produced by Pseudomonas syringae. Subcell. Biochem. 29, 321-341.
4. Bowling, S.A., Clarke, J.D., Liu, Y., Klessig, D.F., and Dong, X. (1997). The cpr5 mutant of Arabidopsis expresses both NPR1-dependent and NPR1-independent resistance. Plant Cell 9, 1573-1584.
5. Butt, A., Mousley, C., Morris, K., Beynon, J., Can, C., Holub, E., Greenberg, J.T., and Buchanan-Wollaston, V. (1998). Differential expression of a senescence-enhanced metallothionein gene in Arabidopsis in response to isolates of Peronospora parasitica and Pseudomonas syringae. Plant J. 16, 209-221.
6. Cao, H., Bowling, S.A., Gordon, A.S., and Dong, X. (1994). Characterization of an Arabidopsis mutant that is nonresponsive to inducers of systemic acquired resistance. Plant Cell 6, 1583-1592.
7. Cao, H., Glazebrook, J., Clarke, J.D., Volko, S., and Dong, X. (1997). The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats. Cell 88, 57-63.
8. Carswell, G.K., Johnson, C.M., Shillito, R.D., and Harms, C.T. (1989). O-acetylsalicylic acid promotes colony formation from protoplasts of an elite maize inbred. Plant Cell Rep. 8, 282-284.
9. Clarke, J.D., Liu, Y., Klessig, D.F., and Dong, X. (1998). Uncoupling PR gene expression from NPR1 and bacterial resistance: Characterization of the dominant Arabidopsis cpr6-1 mutant. Plant Cell 10, 557-569.
10. Delaney, T.P., Uknes, S., Vernooij, B., Friedrich, L., Weymann, K., Negrotto, D., Gaffney, T., Gut-Rella, M., Kessmann, H., Ward, E., and Ryals, J. (1994). A central role of salicylic acid in plant disease resistance. Science 266, 1247-1250.
11. Delaney, T.P., Friedrich, L., and Ryals, J.A. (1995). Arabidopsis signal transduction mutant defective in chemically and biologically induced disease resistance. Proc. Natl. Acad. Sci. USA 92, 6602-6606.
12. Evan, G., and Littlewood, T. (1998). A matter of life and cell death. Science 281, 1317-1322.
13. Fujita, T., Kouchi, H., Ichikawa, T., and Syono, K. (1994). Cloning of cDNAs for genes that are specifically or preferentially expressed during the development of tobacco genetic tumors. Plant J. 5, 645-654.
14. Glazebrook, J., and Ausubel, F.M. (1994). Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens. Proc. Natl. Acad. Sci. USA 91, 8955-8959.
15. Glazebrook, J., Rogers, E.E., and Ausubel, F.M. (1996). Isolation of Arabidopsis mutants with enhanced disease susceptibility by direct screening. Genetics 143, 973-982.
16. Gopalan, S., Bauer, D.W., Alfano, J.R., Loniello, A.O., He, S.Y., and Collmer, A. (1996). Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence on the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death. Plant Cell 8, 1095-1105.
17. Greenberg, J.T. (1997). Programmed cell death in plant-pathogen interactions. Annu. Rev. Plant Physiol. Plant Mol. Biol. 48, 525-545.
18. Greenberg, J.T., Guo, A., Klessig, D.F., and Ausubel, F.M. (1994). Programmed cell death in plants: A pathogen-triggered response activated coordinately with multiple defense functions. Cell 77, 551-563.
19. Hammond-Kosack, K.E., Silverman, P., Raskin, I., and Jones, J.D.G. (1996). Race-specific elicitors of Cladosporium fulvum induce changes in cell morphology and the synthesis of ethylene and salicylic acid in tomato plants carrying the corresponding Cf disease resistance gene. Plant Physiol. 110, 1381-1394.
20. Jabs, T., Dietrich, R.A., and Dangl, J.L. (1996). Initiation of runaway cell death in an Arabidopsis mutant by extracellular superoxide. Science 273, 1853-1856.
21. Jia, S.R., Kumar, P.P., and Kush, A. (1996). Oxidative stress in Agrobacterium-induced tumors on Kalanchoe plants. Plant J. 10, 545-551.
22. Lavermicocca, P., Sante Iacobellis, N., Simmaco, M., and Graniti, A. (1997). Biological properties and spectrum of activity of Pseudomonas syringae pv. syringae toxins. Physiol. Mol. Plant Pathol. 50, 129-140.
23. Lawton, K.A., Potter, S.L., Uknes, S., and Ryals, J. (1994). Acquired resistance signal transduction in Arabidopsis is ethylene independent. Plant Cell 6, 581-588.
24. Lawton, K.A., Friedrich, L., Hunt, M., Weymann, K., Delaney, T., Kessmann, H., Staub, T., and Ryals, J. (1996). Benzothiadiazole induces disease resistance in Arabidopsis by activation of the systemic acquired resistance signal transduction pathway. Plant J. 10, 71-82.
25. Leister, R.T., Ausubel, F.M., and Katagiri, F. (1996). Molecular recognition of pathogen attack occurs inside of plant cells in plant disease resistance specified by the Arabidopsis genes RPS2 and RPM1. Proc. Natl. Acad. Sci. USA 93, 15497-15502.
26. Mindrinos, M., Katagiri, F., Yu, G.L., and Ausubel, F.M. (1994). The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats. Cell 78, 1089-1099.
27. Mittal, S., and Davis, K.R. (1995). Role of the phytotoxin coronatine in the infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato. Mol. Plant-Microbe. Interact. 8, 165-171.
28. Mo, Y.Y., and Gross, D.C. (1991). Plant signal molecules activate the syrB gene, which is required for syringomycin production by Pseudomonas syringae pv. syringae. J. Bacteriol. 173, 5784-5792.
29. Nagy, F., Kay, S.A., and Chua, N.-H. (1988). Analysis of gene expression in transgenic plants. In Plant Molecular Biology Manual, S.B. Gelvin, R.A. Schilperoort, and D.P.S. Verma, eds (Dordrecht, The Netherlands: Kluwer Academic Publishers), pp. 1-29.
30. 2. Plant Physiol. 115, 137-149.
31. Reuber, T.L., and Ausubel, F.M. (1996). Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes. Plant Cell 8, 241-249.
32. Ryals, J.A., Neuenschwander, U.H., Willits, M.G., Molina, A., Steiner, H., and Hunt, M.D. (1996). Systemic acquired resistance. Plant Cell 8, 1809-1819.
33. Shah, J., Kachroo, P., and Klessig, D.F. (1999). The Arabidopsis ssi1 mutation restores pathogenesis-related gene expression in npr1 plants and renders defensin gene expression salicylic acid dependent. Plant Cell 11, 191-206.
34. Shirasu, K., Nakajima, H., Rajasekhar, V.K., Dixon, R.A., and Lamb, C. (1997). Salicylic acid potentiates an agonist-dependent gain control that amplifies pathogen signals in the activation of defense mechanisms. Plant Cell 9, 261-270.
35. Shulaev, V., Leon, J., and Raskin, I. (1995). Is salicylic acid a translocated signal of systemic acquired resistance in tobacco? Plant Cell 7, 1691-1701.
36. Tenhaken, R., and Rubel, C. (1997). Salicylic acid is needed in hypersensitive cell death in soybean but does not act as a catalase inhibitor. Plant Physiol. 115, 291-298.
37. Thulke, O., and Conrath, U. (1998). Salicylic acid has a dual role in the activation of defence-related genes in parsley. Plant J. 14, 35-42.
38. Uknes, S., Mauch-Mani, B., Moyer, M., Potter, S., Williams, S., Dincher, S., Chandler, D., Slusarenko, A., Ward, E., and Ryals, J. (1992). Acquired resistance in Arabidopsis. Plant Cell 4, 645-656.
39. Vernooij, B., Friedrich, L., Morse, A., Reist, R., Kolditz-Jawhar, R., Ward, E., Uknes, S., Kessmann, H., and Ryals, J. (1994). Salicylic acid is not the translocated signal responsible for inducing systemic acquired resistance but is required in signal transduction. Plant Cell 6, 959-965.
40. Weymann, K., Hunt, M., Uknes, S., Neuenschwander, U., Lawton, K., Steiner, H.Y., and Ryals, J. (1995). Suppression and restoration of lesion formation in Arabidopsis lsd mutants. Plant Cell 7, 2013-2022.
41. Yu, I.C., Parker, J., and Bent, A.F. (1998). Gene-for-gene disease resistance without the hypersensitive response in Arabidopsis dnd1 mutant. Proc. Natl. Acad. Sci. USA 95, 7819-7824.
42. Zhao, J., and Last, R.L. (1996). Coordinate regulation of the tryptophan biosynthetic pathway and indolic phytoalexin accumulation in Arabidopsis. Plant Cell 8, 2235-2244.
43. Zhao, J., Williams, C.C., and Last, R.L. (1998). Induction of Arabidopsis tryptophan pathway enzymes and camalexin by amino acid starvation, oxidative stress, and an abiotic elicitor. Plant Cell 10, 359-370.
44. Zhou, N., Tootle, T.L., Tsui, F., Klessig, D.F., and Glazebrook, J. (1998). PAD4 functions upstream from salicylic acid to control defense responses in Arabidopsis. Plant Cell 10, 1021-1030.