Binding of AR-1-144, a tri-imidazole DNA minor groove binder, to CCGG sequence analyzed by NMR spectroscopy

European Journal of Biochemistry

Volumn 263, Issue 3, 1999, Pages 646-655

  Yang, Xiang Lei ^a   Kaenzig, Crystal ^b   Lee, Moses ^b   Wang, Andrew H J ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b FURMAN UNIVERSITY   (United States)

Author keywords

Anti cancer drug; DNA structure; Drug design; Sequence specific recognition

Indexed keywords

DISTAMYCIN A; IMIDAZOLE DERIVATIVE; N [2 (DIMETHYLAMINO)ETHYL] 1 METHYL 4 [1 METHYL 4 (4 FORMAMIDO 1 METHYLIMIDAZOLE 2 CARBOXAMIDO)IMIDAZOLE 2 CARBOXAMIDO]IMIDAZOLE 2 CARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; BINDING AFFINITY; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; DNA FLANKING REGION; DRUG DNA BINDING; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE;

BASE SEQUENCE; BINDING SITES; CIRCULAR DICHROISM; DIMERIZATION; DISTAMYCINS; DNA; KINETICS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES;

EID: 0033179346     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00515.x     Document Type: Article

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