Linked lexitropsins and the in vitro inhibition of HIV-1 reverse transcriptase RNA-directed DNA polymerization: A novel induced-fit of 3,5 m- pyridyl bisdistamycin to enzyme-associated template-primer

Biochemistry

Volumn 35, Issue 48, 1996, Pages 15397-15410

  Filipowsky, Mark E ^a   Kopka, Mary L ^a,b   Brazil Zison, Michelle ^a   Lown, J William ^a,c   Dickerson, Richard E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Molecular Biology Institute   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; 4',6 DIAMIDINO 2 PHENYLINDOLE; CONGOCIDINE; DIMINAZENE ACETURATE; DISTAMYCIN A; DNA; LEXITROPSIN; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING COMPETITION; CONTROLLED STUDY; DNA TEMPLATE; DRUG DNA BINDING; DRUG STRUCTURE; ENZYME SUBSTRATE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; VIRUS TRANSCRIPTION;

ANTIVIRAL AGENTS; BISBENZIMIDE; DIMINAZENE; DISTAMYCINS; DNA POLYMERASE I; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HIV-1 REVERSE TRANSCRIPTASE; INDOLES; KINETICS; MODELS, MOLECULAR; NETROPSIN; RNA-DIRECTED DNA POLYMERASE; TEMPLATES, GENETIC; THYMINE NUCLEOTIDES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0029905747     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961604b     Document Type: Article

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