-
2
-
-
0029142564
-
Overexpression of integral membrane proteins for structural studies
-
Grisshammer R, Tate CG: Overexpression of integral membrane proteins for structural studies. Q Rev Biophys 1995, 28:315-422.
-
(1995)
Q Rev Biophys
, vol.28
, pp. 315-422
-
-
Grisshammer, R.1
Tate, C.G.2
-
3
-
-
0032478818
-
+ conduction and selectivity
-
+ channels
-
+ channels.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Cabral, J.M.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
4
-
-
0032545321
-
Structure of the MscL homolog from Mycobacterium tuberculosis: A gated mechanosensitive ion channel
-
The crystal structure of the M. tuberculosis mechanosensitive channel (MscL) at 3.5 Å resolution details both the pentameric organization of the channel and a potential mechanism of gating
-
Chang G, Spencer RH, Lee AT, Barclay MT, Rees DC: Structure of the MscL homolog from Mycobacterium tuberculosis: A gated mechanosensitive ion channel. Science 1998, 282:2220-2226. The crystal structure of the M. tuberculosis mechanosensitive channel (MscL) at 3.5 Å resolution details both the pentameric organization of the channel and a potential mechanism of gating.
-
(1998)
Science
, vol.282
, pp. 2220-2226
-
-
Chang, G.1
Spencer, R.H.2
Lee, A.T.3
Barclay, M.T.4
Rees, D.C.5
-
5
-
-
0030986861
-
Mechanical transduction by ion channels: How forces reach the channel
-
Edited by Froehner SC. New York: Rockefeller University Press
-
Sachs F: Mechanical transduction by ion channels: How forces reach the channel. In Cytoskeletal Regulation of Membrane Function. Edited by Froehner SC. New York: Rockefeller University Press; 1997:209-218.
-
(1997)
Cytoskeletal Regulation of Membrane Function
, pp. 209-218
-
-
Sachs, F.1
-
6
-
-
0001793255
-
The molecular basis of the mechanical senses: One mechanism or many?
-
Kernan M: The molecular basis of the mechanical senses: One mechanism or many? J NIH Res 1997, 9:32-36.
-
(1997)
J NIH Res
, vol.9
, pp. 32-36
-
-
Kernan, M.1
-
7
-
-
0027939046
-
The cloning of a mechano-gated membrane ion-channel
-
Hamill OP, McBride DW: The cloning of a mechano-gated membrane ion-channel. Trends Neurosci 1994, 17:439-443.
-
(1994)
Trends Neurosci
, vol.17
, pp. 439-443
-
-
Hamill, O.P.1
McBride, D.W.2
-
9
-
-
0028942853
-
Mechanosensitive channels
-
Sackin H: Mechanosensitive channels. Annu Rev Physiol 1995, 57:333-353.
-
(1995)
Annu Rev Physiol
, vol.57
, pp. 333-353
-
-
Sackin, H.1
-
10
-
-
0031728747
-
Mechanosensitive channels of bacteria
-
Edited by Conn PM. San Diego: Academic Press Inc. A comprehensive review on the molecular and functional characterization of mechanosensitive channels in prokaryotes
-
Blount P, Sukharev SI, Moe PC, Martinac B, Kung C: Mechanosensitive channels of bacteria. In Methods in Enzymology, Vol 294. Edited by Conn PM. San Diego: Academic Press Inc; 1999:458-482. A comprehensive review on the molecular and functional characterization of mechanosensitive channels in prokaryotes.
-
(1999)
Methods in Enzymology
, vol.294
, pp. 458-482
-
-
Blount, P.1
Sukharev, S.I.2
Moe, P.C.3
Martinac, B.4
Kung, C.5
-
11
-
-
0030477115
-
Towards an understanding of the structural and functional properties of MscL, a mechanosensitive channel in bacteria
-
Blount P, Sukharev SI, Moe PC, Nagle SK, Kung C: Towards an understanding of the structural and functional properties of MscL, a mechanosensitive channel in bacteria. Biol Cell 1996, 87:1-8.
-
(1996)
Biol Cell
, vol.87
, pp. 1-8
-
-
Blount, P.1
Sukharev, S.I.2
Moe, P.C.3
Nagle, S.K.4
Kung, C.5
-
12
-
-
0028224356
-
A large-conductance mechanosensitive channel in E. coli encoded by MscL alone
-
Sukharev SI, Blount P, Martinac B, Blattner FR, Kung C: A large-conductance mechanosensitive channel in E. coli encoded by MscL alone. Nature 1994, 368:265-268.
-
(1994)
Nature
, vol.368
, pp. 265-268
-
-
Sukharev, S.I.1
Blount, P.2
Martinac, B.3
Blattner, F.R.4
Kung, C.5
-
13
-
-
0030901623
-
Mechanosensitive channels of Escherichia coli, the MscL gene, protein, and activities
-
Sukharev SI, Blount P, Martinac B, Kung C: Mechanosensitive channels of Escherichia coli, the MscL gene, protein, and activities. Annu Rev Physiol 1997, 59:633-657.
-
(1997)
Annu Rev Physiol
, vol.59
, pp. 633-657
-
-
Sukharev, S.I.1
Blount, P.2
Martinac, B.3
Kung, C.4
-
14
-
-
0032530833
-
One face of a transmembrane helix is crucial in mechanosensitive channel gating
-
The characterization of random mutations in the mscl gene that result in gain-of-function phenotypes. These mutants displayed slow or no-growth phenotypes as a result of solute loss out of the cell and were correlated with a hypersensitivity to membrane tension
-
Ou XR, Blount P, Hoffman RJ, Kung C: One face of a transmembrane helix is crucial in mechanosensitive channel gating. Proc Natl Acad Sci USA 1998, 95:11471-11475. The characterization of random mutations in the mscl gene that result in gain-of-function phenotypes. These mutants displayed slow or no-growth phenotypes as a result of solute loss out of the cell and were correlated with a hypersensitivity to membrane tension.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11471-11475
-
-
Ou, X.R.1
Blount, P.2
Hoffman, R.J.3
Kung, C.4
-
15
-
-
0029813032
-
Membrane topology and multimeric structure of a mechanosensitive channel protein of Escherichia coli
-
Blount P, Sukharev SI, Moe PC, Schroeder MJ, Guy HR, Kung C: Membrane topology and multimeric structure of a mechanosensitive channel protein of Escherichia coli. EMBO J 1996, 15:4798-4805.
-
(1996)
EMBO J
, vol.15
, pp. 4798-4805
-
-
Blount, P.1
Sukharev, S.I.2
Moe, P.C.3
Schroeder, M.J.4
Guy, H.R.5
Kung, C.6
-
16
-
-
0031587748
-
Cross-linking studies and membrane localization and assembly of radiolabelled large mechanosensitive ion channel (MscL) of Escherichia coli
-
Häse CC, Minchin RF, Kloda A, Martinac B: Cross-linking studies and membrane localization and assembly of radiolabelled large mechanosensitive ion channel (MscL) of Escherichia coli. Biochem Biophys Res Commun 1997, 232:777-782.
-
(1997)
Biochem Biophys Res Commun
, vol.232
, pp. 777-782
-
-
Häse, C.C.1
Minchin, R.F.2
Kloda, A.3
Martinac, B.4
-
17
-
-
0345543722
-
A hexameric transmembrane pore revealed by two-dimensional crystallization of the large mechanosensitive ion channel (MscL) of Escherichia coli
-
Saint N, Lacapère JJ, Gu LQ, Ghazi A, Martinac B, Rigaud JL: A hexameric transmembrane pore revealed by two-dimensional crystallization of the large mechanosensitive ion channel (MscL) of Escherichia coli. J Biol Chem 1998, 273:14667-14670.
-
(1998)
J Biol Chem
, vol.273
, pp. 14667-14670
-
-
Saint, N.1
Lacapère, J.J.2
Gu, L.Q.3
Ghazi, A.4
Martinac, B.5
Rigaud, J.L.6
-
18
-
-
0000209812
-
Re-examining the multimeric structure of the large conductance bacterial mechanosensitive channel, MscL
-
Sukharev S, Schroeder MJ, McCaslin DR: Re-examining the multimeric structure of the large conductance bacterial mechanosensitive channel, MscL. Biophys J 1999, 76:A138.
-
(1999)
Biophys J
, vol.76
-
-
Sukharev, S.1
Schroeder, M.J.2
McCaslin, D.R.3
-
19
-
-
7144257172
-
Functional and structural conservation in the mechanosensitive channel MscL implicates elements crucial for mechanosensation
-
The identification and characterization of multiple MscL homologs demonstrated conservation both in sequence and in function for these channels
-
Moe PC, Blount P, Kung C: Functional and structural conservation in the mechanosensitive channel MscL implicates elements crucial for mechanosensation. Mol Microbiol 1998, 28:583-592. The identification and characterization of multiple MscL homologs demonstrated conservation both in sequence and in function for these channels.
-
(1998)
Mol Microbiol
, vol.28
, pp. 583-592
-
-
Moe, P.C.1
Blount, P.2
Kung, C.3
-
20
-
-
0032524340
-
Mechanosensitive ion channels of the archaeon Haloferax volcanii
-
The characterization of mechanosensitive channels in a halophilic archaeon with properties similar to MscL suggests the ubiquity and importance of these channels throughout evolution
-
Le Dain AC, Saint N, Kloda A, Ghazi A, Martinac B: Mechanosensitive ion channels of the archaeon Haloferax volcanii. J Biol Chem 1998, 273:12116-12119. The characterization of mechanosensitive channels in a halophilic archaeon with properties similar to MscL suggests the ubiquity and importance of these channels throughout evolution.
-
(1998)
J Biol Chem
, vol.273
, pp. 12116-12119
-
-
Le Dain, A.C.1
Saint, N.2
Kloda, A.3
Ghazi, A.4
Martinac, B.5
-
21
-
-
0001642893
-
A novel mechanosensitive ion channel in the thermophilic cell wall-less archaeon Thermoplasma volcanium
-
Kloda A, Martinac B: A novel mechanosensitive ion channel in the thermophilic cell wall-less archaeon Thermoplasma volcanium. Biophys J 1999, 76:A201.
-
(1999)
Biophys J
, vol.76
-
-
Kloda, A.1
Martinac, B.2
-
22
-
-
0031463940
-
Mutations in a bacterial mechanosensitive channel change the cellular response to osmotic stress
-
Blount P, Schroeder MJ, Kung C: Mutations in a bacterial mechanosensitive channel change the cellular response to osmotic stress. J Biol Chem 1997, 272:32150-32157.
-
(1997)
J Biol Chem
, vol.272
, pp. 32150-32157
-
-
Blount, P.1
Schroeder, M.J.2
Kung, C.3
-
23
-
-
0033039194
-
Mechanosensitive channel functions to alleviate the cell lysis of marine bacterium, Vibrio alginolyticus, by osmotic downshock
-
Nakamaru Y, Takahashi Y, Unemoto T, Nakamura T: Mechanosensitive channel functions to alleviate the cell lysis of marine bacterium, Vibrio alginolyticus, by osmotic downshock. FEBS Lett 1999, 444:170-172.
-
(1999)
FEBS Lett
, vol.444
, pp. 170-172
-
-
Nakamaru, Y.1
Takahashi, Y.2
Unemoto, T.3
Nakamura, T.4
-
24
-
-
0030694290
-
Highly constrained multiple-copy refinement of protein crystal structures
-
Pellegrini M, Gronbech-Jensen N, Kelly JA, Pfluegl GM, Yeates TO: Highly constrained multiple-copy refinement of protein crystal structures. Proteins 1997, 29:426-432.
-
(1997)
Proteins
, vol.29
, pp. 426-432
-
-
Pellegrini, M.1
Gronbech-Jensen, N.2
Kelly, J.A.3
Pfluegl, G.M.4
Yeates, T.O.5
-
25
-
-
0025943869
-
Exploration of disorder in protein structures by X-ray restrained molecular dynamics
-
Kuriyan J, Osapay K, Burley SK, Brunger AT, Hendrickson WA, Karplus M: Exploration of disorder in protein structures by X-ray restrained molecular dynamics. Proteins 1991, 10:340-358.
-
(1991)
Proteins
, vol.10
, pp. 340-358
-
-
Kuriyan, J.1
Osapay, K.2
Burley, S.K.3
Brunger, A.T.4
Hendrickson, W.A.5
Karplus, M.6
-
26
-
-
0028921479
-
Acetylcholine receptor channel imaged in the open state
-
Unwin N: Acetylcholine receptor channel imaged in the open state. Nature 1995, 373:37-43.
-
(1995)
Nature
, vol.373
, pp. 37-43
-
-
Unwin, N.1
-
27
-
-
0032102496
-
The location of the gate in the acetylcholine receptor channel
-
Wilson GG, Karlin A: The location of the gate in the acetylcholine receptor channel. Neuron 1998, 20:1269-1287.
-
(1998)
Neuron
, vol.20
, pp. 1269-1287
-
-
Wilson, G.G.1
Karlin, A.2
-
29
-
-
0032479997
-
+ channel
-
+ channel. EMBO J 1998, 17:4283-4290.
-
(1998)
EMBO J
, vol.17
, pp. 4283-4290
-
-
Patel, A.J.1
Honore, E.2
Maingret, F.3
Lesage, F.4
Fink, M.5
Duprat, F.6
Lazdunski, M.7
-
30
-
-
0030922654
-
Molecular dissection of the large mechanosensitive ion channel (MscL) of E. coli: Mutants with altered channel gating and pressure sensitivity
-
Häse CC, LeDain AC, Martinac B: Molecular dissection of the large mechanosensitive ion channel (MscL) of E. coli: Mutants with altered channel gating and pressure sensitivity. J Membr Biol 1997, 157:17-25.
-
(1997)
J Membr Biol
, vol.157
, pp. 17-25
-
-
Häse, C.C.1
LeDain, A.C.2
Martinac, B.3
-
31
-
-
4243544354
-
Dynamics of bacterial mechanosensitive channel complexes (MscL) as viewed by time-resolved current records
-
Sukharev SI: Dynamics of bacterial mechanosensitive channel complexes (MscL) as viewed by time-resolved current records. Biophys J 1998, 74:A324.
-
(1998)
Biophys J
, vol.74
-
-
Sukharev, S.I.1
-
32
-
-
0025114667
-
Mechanosensitive ion channels of Escherichia coli activated by amphipaths
-
Martinac B, Adler J, Kung C: Mechanosensitive ion channels of Escherichia coli activated by amphipaths. Nature 1990, 348:261-263
-
(1990)
Nature
, vol.348
, pp. 261-263
-
-
Martinac, B.1
Adler, J.2
Kung, C.3
-
33
-
-
0025837411
-
Mechanosensitive ion channels as reporters of bilayer expansion - A theoretical model
-
Markin VS, Martinac B: Mechanosensitive ion channels as reporters of bilayer expansion - A theoretical model. Biophys J 1991, 60:1120-1127.
-
(1991)
Biophys J
, vol.60
, pp. 1120-1127
-
-
Markin, V.S.1
Martinac, B.2
-
35
-
-
0030866749
-
Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli
-
Cruickshank CC, Minchin RF, LeDain AC, Martinac B: Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli. Biophys J 1997, 73:1925-1931.
-
(1997)
Biophys J
, vol.73
, pp. 1925-1931
-
-
Cruickshank, C.C.1
Minchin, R.F.2
LeDain, A.C.3
Martinac, B.4
-
36
-
-
14444277712
-
Release of thioredoxin via the mechanosensitive channel MscL during osmotic downshock of Escherichia coli cells
-
- strains during osmotic downshock demonstrates that MscL participates in the rapid release of osmolytes under these conditions and is specifically responsible for the release of thioredoxin
-
- strains during osmotic downshock demonstrates that MscL participates in the rapid release of osmolytes under these conditions and is specifically responsible for the release of thioredoxin.
-
(1998)
J Biol Chem
, vol.273
, pp. 26670-26674
-
-
Ajouz, B.1
Berrier, C.2
Garrigues, A.3
Besnard, M.4
Ghazi, A.5
-
38
-
-
0031853989
-
Porin mutants with new channel properties
-
Schmid B, Maveyraud L, Krömer M, Schulz GE: Porin mutants with new channel properties. Protein Sci 1998, 7:1603-1611.
-
(1998)
Protein Sci
, vol.7
, pp. 1603-1611
-
-
Schmid, B.1
Maveyraud, L.2
Krömer, M.3
Schulz, G.E.4
-
39
-
-
0026244229
-
Molscript - A program to produce both detailed and schematic plots of protein structures
-
Kraulis PJ: Molscript - A program to produce both detailed and schematic plots of protein structures. J Appl Crystallogr 1991, 24:946-950.
-
(1991)
J Appl Crystallogr
, vol.24
, pp. 946-950
-
-
Kraulis, P.J.1
-
40
-
-
0029016182
-
Classical electrostatics in biology and chemistry
-
Honig B, Nicholls A: Classical electrostatics in biology and chemistry. Science 1995, 268:1144-1149.
-
(1995)
Science
, vol.268
, pp. 1144-1149
-
-
Honig, B.1
Nicholls, A.2
-
41
-
-
0030404988
-
HOLE: A program for the analysis of the pore dimensions of ion channel structural models
-
Smart OS, Neduvelil JG, Wang X, Wallace BA, Sansom MS: HOLE: A program for the analysis of the pore dimensions of ion channel structural models. J Mol Graph 1996, 14:354-360.
-
(1996)
J Mol Graph
, vol.14
, pp. 354-360
-
-
Smart, O.S.1
Neduvelil, J.G.2
Wang, X.3
Wallace, B.A.4
Sansom, M.S.5
-
42
-
-
0031574072
-
The Clustal X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG: The Clustal X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 1997, 25:4876-4882.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
44
-
-
0001849178
-
Channel gate! Tension, leak and disclosure
-
The authors provide insights into the relationship between residues that affect the gating of MscL and their localization within the crystal structure of Tb-MscL
-
Batiza AF, Rayment I, Kung C: Channel gate! Tension, leak and disclosure. Structure 1999, 7:R99-R103. The authors provide insights into the relationship between residues that affect the gating of MscL and their localization within the crystal structure of Tb-MscL.
-
(1999)
Structure
, vol.7
-
-
Batiza, A.F.1
Rayment, I.2
Kung, C.3
|