-
1
-
-
0021358883
-
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
-
Bradley A, Evans M, Kaufman MH and Robertson E (1984) Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309: 255-256.
-
(1984)
Nature
, vol.309
, pp. 255-256
-
-
Bradley, A.1
Evans, M.2
Kaufman, M.H.3
Robertson, E.4
-
2
-
-
0028112003
-
Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats
-
Brand CL, Rolin B, Jorgensen PN, Svendsen I, Kristensen JS and Holst JJ (1994) Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats. Diabetologia 37: 985-993.
-
(1994)
Diabetologia
, vol.37
, pp. 985-993
-
-
Brand, C.L.1
Rolin, B.2
Jorgensen, P.N.3
Svendsen, I.4
Kristensen, J.S.5
Holst, J.J.6
-
3
-
-
0029840285
-
Molecular and cellular aspects of the glucagon receptor - Role in diabetes and metabolism
-
Burcelin R, Katz EB and Charron MJ (1996) Molecular and cellular aspects of the glucagon receptor - role in diabetes and metabolism. Diabetes & Metabolism 22: 373-396.
-
(1996)
Diabetes & Metabolism
, vol.22
, pp. 373-396
-
-
Burcelin, R.1
Katz, E.B.2
Charron, M.J.3
-
4
-
-
0033605578
-
Characterization of a novel, non-peptidyl antagonist of the human glucagon receptor
-
in press
-
Cascieri MA, Koch GE, Ber E, et al. (1999) Characterization of a novel, non-peptidyl antagonist of the human glucagon receptor. J Biol Chem (in press).
-
(1999)
J Biol Chem
-
-
Cascieri, M.A.1
Koch, G.E.2
Ber, E.3
-
5
-
-
0030909710
-
Alterations in receptor activation and divalent-cation activation of agonist binding by deletion of intracellular domains of the glucagon receptor
-
Chicchi GG, Graziano MP, Koch G, et al. (1997) Alterations in receptor activation and divalent-cation activation of agonist binding by deletion of intracellular domains of the glucagon receptor. J Biol Chem 272: 7765-7769.
-
(1997)
J Biol Chem
, vol.272
, pp. 7765-7769
-
-
Chicchi, G.G.1
Graziano, M.P.2
Koch, G.3
-
6
-
-
0009623009
-
The discovery of L-168,049: A potent, orally active glucagon receptor antagonist
-
in press
-
de Laszlo SE, Hacker C, Li B, et al. (1999) The discovery of L-168,049: a potent, orally active glucagon receptor antagonist. Bioorganic and Medicinal Chemistry Letters (in press).
-
(1999)
Bioorganic and Medicinal Chemistry Letters
-
-
De Laszlo, S.E.1
Hacker, C.2
Li, B.3
-
7
-
-
0032081279
-
3adrenergic stimulation of metabolic rate in rhesus monkeys
-
3adrenergic stimulation of metabolic rate in rhesus monkeys. J Clin Imest 101: 2387-2393.
-
(1998)
J Clin Imest
, vol.101
, pp. 2387-2393
-
-
Fisher, M.H.1
Amend, A.M.2
Bach, T.J.3
-
8
-
-
0027092318
-
Molecular basis tor the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580
-
Fong TM, Yu H and Strader CD (1992) Molecular basis tor the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580. J Biol Chem 267: 25668-256671.
-
(1992)
J Biol Chem
, vol.267
, pp. 25668-256671
-
-
Fong, T.M.1
Yu, H.2
Strader, C.D.3
-
9
-
-
0023189783
-
Synthesis of two glucagon antagonists: Receptor binding, adenylate cyclase, and effects on blood plasma glucose levels
-
Gysin B, Johnson DG, Trivedi D and Hruby VJ (1987) Synthesis of two glucagon antagonists: receptor binding, adenylate cyclase, and effects on blood plasma glucose levels. J Med Chem 30: 1409-1415.
-
(1987)
J Med Chem
, vol.30
, pp. 1409-1415
-
-
Gysin, B.1
Johnson, D.G.2
Trivedi, D.3
Hruby, V.J.4
-
10
-
-
0027531638
-
Expression cloning and signaling properties of the rat glucagon receptor
-
Jelinek LJ, Lok S, Rosenberg GB, et al. (1993) Expression cloning and signaling properties of the rat glucagon receptor. Science 259: 1614-1616.
-
(1993)
Science
, vol.259
, pp. 1614-1616
-
-
Jelinek, L.J.1
Lok, S.2
Rosenberg, G.B.3
-
11
-
-
0020471569
-
Hyperglycemia of diabetic rats decreased by a glucagon receptor antagonist
-
Johnson DG, Goebel CU, Hruby VJ, Bregman MD and Trivedi D (1982) Hyperglycemia of diabetic rats decreased by a glucagon receptor antagonist. Science 215: 1115-1116.
-
(1982)
Science
, vol.215
, pp. 1115-1116
-
-
Johnson, D.G.1
Goebel, C.U.2
Hruby, V.J.3
Bregman, M.D.4
Trivedi, D.5
-
12
-
-
0029438042
-
Electroporation of embryonic stem cells for generating transgenic mice and studying in vitro differentiation
-
Nickoloff, JA (ed). Humana Press, Totowa, NJ
-
Mudgett JS and Livelli TJ (1995) Electroporation of embryonic stem cells for generating transgenic mice and studying in vitro differentiation. In: Nickoloff, JA (ed) Methods in Molecular Biology: Animal Cell Electroporation and Electrofusion Protocols, pp. 167-184. Humana Press, Totowa, NJ.
-
(1995)
Methods in Molecular Biology: Animal Cell Electroporation and Electrofusion Protocols
, pp. 167-184
-
-
Mudgett, J.S.1
Livelli, T.J.2
-
13
-
-
0032032847
-
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates A betal-42/43 expression
-
Qian S, Jiang P, Guan XM, Singh G, et al. (1998) Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates A betal-42/43 expression Neuron 20: 611-617.
-
(1998)
Neuron
, vol.20
, pp. 611-617
-
-
Qian, S.1
Jiang, P.2
Guan, X.M.3
Singh, G.4
-
14
-
-
0029788661
-
Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a 'humanized' a beta sequence
-
Reaume AG, Howland DS, Trusko SP, et al. (1996) Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a 'humanized' A beta sequence. J Biol Chem 271: 23380-23388.
-
(1996)
J Biol Chem
, vol.271
, pp. 23380-23388
-
-
Reaume, A.G.1
Howland, D.S.2
Trusko, S.P.3
-
15
-
-
0016374975
-
A highly sensitive adenylate cyclase assay
-
Salomon Y, Londos C and Rodbell M (1974) A highly sensitive adenylate cyclase assay. Anal Biochem 58: 541-548.
-
(1974)
Anal Biochem
, vol.58
, pp. 541-548
-
-
Salomon, Y.1
Londos, C.2
Rodbell, M.3
-
16
-
-
0026023289
-
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
-
Soriano P, Montgomery C, Geske R and Bradley A (1991) Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64: 693-702.
-
(1991)
Cell
, vol.64
, pp. 693-702
-
-
Soriano, P.1
Montgomery, C.2
Geske, R.3
Bradley, A.4
-
17
-
-
0030741533
-
Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis
-
Sullivan PM, Mezdour H, Aratani Y, et al. (1997) Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. J Biol Chem 272: 17972-17980.
-
(1997)
J Biol Chem
, vol.272
, pp. 17972-17980
-
-
Sullivan, P.M.1
Mezdour, H.2
Aratani, Y.3
-
18
-
-
0028970574
-
Interaction of [fluorescein-Trp(25)]glucagon with the human glucagon receptor expressed in Drosophila Schneider-2 cells
-
Tota MR, Xu L, Sirotina A, Strader CD and Graziano MP (1995) Interaction of [fluorescein-Trp(25)]glucagon with the human glucagon receptor expressed in Drosophila Schneider-2 cells. J Biol Chem 270, 26466-26472.
-
(1995)
J Biol Chem
, vol.270
, pp. 26466-26472
-
-
Tota, M.R.1
Xu, L.2
Sirotina, A.3
Strader, C.D.4
Graziano, M.P.5
-
19
-
-
0028557095
-
Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR
-
Zhou L, Dey CR, Wert SE, DuVall MD, Frizzell RA and Whitsett JA (1994) Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR. Science 266: 1705-1708.
-
(1994)
Science
, vol.266
, pp. 1705-1708
-
-
Zhou, L.1
Dey, C.R.2
Wert, S.E.3
DuVall, M.D.4
Frizzell, R.A.5
Whitsett, J.A.6
|