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Volumn 8, Issue 4, 1999, Pages 295-302

Generation of mice expressing the human glucagon receptor with a direct replacement vector

Author keywords

Glucagon; Glucagon receptor; GPCR; Non peptidyl antagonist

Indexed keywords

CYCLIC AMP; EXPRESSION VECTOR; GLUCAGON RECEPTOR; HOMOLOGOUS RECOMBINATION; HORMONE RECEPTOR; MAGNESIUM CHLORIDE; MOUSE;

EID: 0033177983     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008922521461     Document Type: Article
Times cited : (30)

References (19)
  • 1
    • 0021358883 scopus 로고
    • Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
    • Bradley A, Evans M, Kaufman MH and Robertson E (1984) Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309: 255-256.
    • (1984) Nature , vol.309 , pp. 255-256
    • Bradley, A.1    Evans, M.2    Kaufman, M.H.3    Robertson, E.4
  • 2
    • 0028112003 scopus 로고
    • Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats
    • Brand CL, Rolin B, Jorgensen PN, Svendsen I, Kristensen JS and Holst JJ (1994) Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats. Diabetologia 37: 985-993.
    • (1994) Diabetologia , vol.37 , pp. 985-993
    • Brand, C.L.1    Rolin, B.2    Jorgensen, P.N.3    Svendsen, I.4    Kristensen, J.S.5    Holst, J.J.6
  • 3
    • 0029840285 scopus 로고    scopus 로고
    • Molecular and cellular aspects of the glucagon receptor - Role in diabetes and metabolism
    • Burcelin R, Katz EB and Charron MJ (1996) Molecular and cellular aspects of the glucagon receptor - role in diabetes and metabolism. Diabetes & Metabolism 22: 373-396.
    • (1996) Diabetes & Metabolism , vol.22 , pp. 373-396
    • Burcelin, R.1    Katz, E.B.2    Charron, M.J.3
  • 4
    • 0033605578 scopus 로고    scopus 로고
    • Characterization of a novel, non-peptidyl antagonist of the human glucagon receptor
    • in press
    • Cascieri MA, Koch GE, Ber E, et al. (1999) Characterization of a novel, non-peptidyl antagonist of the human glucagon receptor. J Biol Chem (in press).
    • (1999) J Biol Chem
    • Cascieri, M.A.1    Koch, G.E.2    Ber, E.3
  • 5
    • 0030909710 scopus 로고    scopus 로고
    • Alterations in receptor activation and divalent-cation activation of agonist binding by deletion of intracellular domains of the glucagon receptor
    • Chicchi GG, Graziano MP, Koch G, et al. (1997) Alterations in receptor activation and divalent-cation activation of agonist binding by deletion of intracellular domains of the glucagon receptor. J Biol Chem 272: 7765-7769.
    • (1997) J Biol Chem , vol.272 , pp. 7765-7769
    • Chicchi, G.G.1    Graziano, M.P.2    Koch, G.3
  • 7
    • 0032081279 scopus 로고    scopus 로고
    • 3adrenergic stimulation of metabolic rate in rhesus monkeys
    • 3adrenergic stimulation of metabolic rate in rhesus monkeys. J Clin Imest 101: 2387-2393.
    • (1998) J Clin Imest , vol.101 , pp. 2387-2393
    • Fisher, M.H.1    Amend, A.M.2    Bach, T.J.3
  • 8
    • 0027092318 scopus 로고
    • Molecular basis tor the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580
    • Fong TM, Yu H and Strader CD (1992) Molecular basis tor the species selectivity of the neurokinin-1 receptor antagonists CP-96,345 and RP67580. J Biol Chem 267: 25668-256671.
    • (1992) J Biol Chem , vol.267 , pp. 25668-256671
    • Fong, T.M.1    Yu, H.2    Strader, C.D.3
  • 9
    • 0023189783 scopus 로고
    • Synthesis of two glucagon antagonists: Receptor binding, adenylate cyclase, and effects on blood plasma glucose levels
    • Gysin B, Johnson DG, Trivedi D and Hruby VJ (1987) Synthesis of two glucagon antagonists: receptor binding, adenylate cyclase, and effects on blood plasma glucose levels. J Med Chem 30: 1409-1415.
    • (1987) J Med Chem , vol.30 , pp. 1409-1415
    • Gysin, B.1    Johnson, D.G.2    Trivedi, D.3    Hruby, V.J.4
  • 10
    • 0027531638 scopus 로고
    • Expression cloning and signaling properties of the rat glucagon receptor
    • Jelinek LJ, Lok S, Rosenberg GB, et al. (1993) Expression cloning and signaling properties of the rat glucagon receptor. Science 259: 1614-1616.
    • (1993) Science , vol.259 , pp. 1614-1616
    • Jelinek, L.J.1    Lok, S.2    Rosenberg, G.B.3
  • 11
    • 0020471569 scopus 로고
    • Hyperglycemia of diabetic rats decreased by a glucagon receptor antagonist
    • Johnson DG, Goebel CU, Hruby VJ, Bregman MD and Trivedi D (1982) Hyperglycemia of diabetic rats decreased by a glucagon receptor antagonist. Science 215: 1115-1116.
    • (1982) Science , vol.215 , pp. 1115-1116
    • Johnson, D.G.1    Goebel, C.U.2    Hruby, V.J.3    Bregman, M.D.4    Trivedi, D.5
  • 12
    • 0029438042 scopus 로고
    • Electroporation of embryonic stem cells for generating transgenic mice and studying in vitro differentiation
    • Nickoloff, JA (ed). Humana Press, Totowa, NJ
    • Mudgett JS and Livelli TJ (1995) Electroporation of embryonic stem cells for generating transgenic mice and studying in vitro differentiation. In: Nickoloff, JA (ed) Methods in Molecular Biology: Animal Cell Electroporation and Electrofusion Protocols, pp. 167-184. Humana Press, Totowa, NJ.
    • (1995) Methods in Molecular Biology: Animal Cell Electroporation and Electrofusion Protocols , pp. 167-184
    • Mudgett, J.S.1    Livelli, T.J.2
  • 13
    • 0032032847 scopus 로고    scopus 로고
    • Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates A betal-42/43 expression
    • Qian S, Jiang P, Guan XM, Singh G, et al. (1998) Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates A betal-42/43 expression Neuron 20: 611-617.
    • (1998) Neuron , vol.20 , pp. 611-617
    • Qian, S.1    Jiang, P.2    Guan, X.M.3    Singh, G.4
  • 14
    • 0029788661 scopus 로고    scopus 로고
    • Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a 'humanized' a beta sequence
    • Reaume AG, Howland DS, Trusko SP, et al. (1996) Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a 'humanized' A beta sequence. J Biol Chem 271: 23380-23388.
    • (1996) J Biol Chem , vol.271 , pp. 23380-23388
    • Reaume, A.G.1    Howland, D.S.2    Trusko, S.P.3
  • 15
    • 0016374975 scopus 로고
    • A highly sensitive adenylate cyclase assay
    • Salomon Y, Londos C and Rodbell M (1974) A highly sensitive adenylate cyclase assay. Anal Biochem 58: 541-548.
    • (1974) Anal Biochem , vol.58 , pp. 541-548
    • Salomon, Y.1    Londos, C.2    Rodbell, M.3
  • 16
    • 0026023289 scopus 로고
    • Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
    • Soriano P, Montgomery C, Geske R and Bradley A (1991) Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64: 693-702.
    • (1991) Cell , vol.64 , pp. 693-702
    • Soriano, P.1    Montgomery, C.2    Geske, R.3    Bradley, A.4
  • 17
    • 0030741533 scopus 로고    scopus 로고
    • Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis
    • Sullivan PM, Mezdour H, Aratani Y, et al. (1997) Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. J Biol Chem 272: 17972-17980.
    • (1997) J Biol Chem , vol.272 , pp. 17972-17980
    • Sullivan, P.M.1    Mezdour, H.2    Aratani, Y.3
  • 18
    • 0028970574 scopus 로고
    • Interaction of [fluorescein-Trp(25)]glucagon with the human glucagon receptor expressed in Drosophila Schneider-2 cells
    • Tota MR, Xu L, Sirotina A, Strader CD and Graziano MP (1995) Interaction of [fluorescein-Trp(25)]glucagon with the human glucagon receptor expressed in Drosophila Schneider-2 cells. J Biol Chem 270, 26466-26472.
    • (1995) J Biol Chem , vol.270 , pp. 26466-26472
    • Tota, M.R.1    Xu, L.2    Sirotina, A.3    Strader, C.D.4    Graziano, M.P.5
  • 19
    • 0028557095 scopus 로고
    • Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR
    • Zhou L, Dey CR, Wert SE, DuVall MD, Frizzell RA and Whitsett JA (1994) Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR. Science 266: 1705-1708.
    • (1994) Science , vol.266 , pp. 1705-1708
    • Zhou, L.1    Dey, C.R.2    Wert, S.E.3    DuVall, M.D.4    Frizzell, R.A.5    Whitsett, J.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.