Nonapeptide analogues containing (R)-3-hydroxybutanoate and β- homoalanine oligomers: Synthesis and binding affinity to a class I major histocompatibility complex protein

Journal of Medicinal Chemistry

Volumn 42, Issue 13, 1999, Pages 2318-2331

  Poenaru, Sorana ^a,c   Lamas, José R ^b   Folkers, Gerd ^a   De Castro, José A López ^b   Seebach, Dieter ^a   Rognan, Didier ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID DERIVATIVE; BETA HOMOALANINE DERIVATIVE; HLA B ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OLIGOMER; PEPTIDE DERIVATIVE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; VACCINE;

ANIMAL CELL; ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG SYNTHESIS; IN VITRO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR MODEL; MOUSE; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE;

3-HYDROXYBUTYRIC ACID; ALANINE; ALLELES; ANIMALS; CELL LINE; EPITOPES; HIV ENVELOPE PROTEIN GP120; HIV-1; HLA-B27 ANTIGEN; LIGANDS; MODELS, MOLECULAR; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; POLYMERS; PROTEIN BINDING; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033168016     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm981123l     Document Type: Article

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