Metabolic Analysis of Glutamate Production by Corynebacterium glutamicum

Metabolic Engineering

Volumn 1, Issue 3, 1999, Pages 224-231

  Gourdon, Pierre ^a   Lindley, Nicholas D ^a  

^a INSA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; BIOMEDICAL ENGINEERING; BIOREACTOR; BIOSYNTHESIS; BIOTECHNOLOGY; CORYNEBACTERIUM; FERMENTATION; GLYCOLYSIS; KINETICS; METABOLISM;

BIOMEDICAL ENGINEERING; BIOREACTORS; BIOTECHNOLOGY; CORYNEBACTERIUM; FERMENTATION; GLUTAMIC ACID; GLYCOLYSIS; KINETICS; NAD;

EID: 0033155976     PISSN: 10967176     EISSN: None     Source Type: Journal    
DOI: 10.1006/mben.1999.0122     Document Type: Article

References (27)

1. Cocaign-Bousquet M., Guyonvarch A., Lindley N. D. Growth rate dependent modulation of carbon flux through central metabolism and the kinetic consequences for glucose-limited chemostat cultures of Corynebacterium glutamicum. Appl. Env. Microbiol. 62:1996;429-436.
2. +-dependent glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans. J. Biol. Chem. 254:1979;1134-1142.
3. Dominguez H., Nezondet C., Lindley N. D., Cocaign M. Modified carbon flux during oxygen-limited growth of Corynebacterium glutamicum and the consequences for amino acid production. Biotechnol. Lett. 15:1993;449-454.
4. Dominguez H., Rollin C., Guyonvarch A., Guerquin-Kern J. L., Cocaign-Bousquet M., Lindley N. D. Carbon-flux distribution in the central metabolic pathways of Corynebacterium glutamicum during growth on fructose. Eur. J. Biochem. 254:1998;96-102.
5. + ratio. J. Bacteriol. 179:1997;5282-5287.
6. Guillouet S., Engasser J. M. Growth of Corynebacterium glutamicum in glucose-limited continuous cultures under high osmotic pressure. Influence of growth rate on the intracellular accumulation of proline, glutamate and trehalose. Appl. Microbiol. Biotechnol. 44:1995;496-500.
7. Hertz P. F. Chaîne respiratoire et déshydrogénases flaviniques chez Corynebacterium melassecola ATCC 17965: Contribution à l'étude des voies d'utilisation de coenzymes intervenant dans les réactions d'oxydoréduction. 1998;Université Paris Sud, France.
8. 13C Nuclear magnetic resonance studies of glucose metabolism in L-glutamic acid and L-lysine fermentation by Corynebacterium glutamicum. J. Gen. Appl. Microbiol. 37:1991;157-165.
9. Kawahara Y., Takahashi-Fuke K., Shimizu E., Nakamatsu T., Nakamori S. Relationship between the glutamate production and the activity of 2-oxoglutarate dehydrogenase in Brevibacterium lactofermentum. Biosci. Biotech. Biochem. 61:1997;1109-1112.
10. 2 by the acetyl-CoA pathway. J. Gen. Microbiol. 139:1993;1861-1868.
11. Le Bras G., de la Torre F., Branny P., Garel J. R. Enzymatic and genetic regulation of glycolysis in Lactobacillus delbrueckii subsp. bulgaricus. Lait. 78:1998;85-90.
12. Marx A., de Graaf A. A., Wiechert W., Eggeling L., Sahm H. Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolic balancing. Biotechnol. Bioeng. 49:1996;111-129.
13. Marx A., Striegel K., de Graaf A. A., Sahm H., Eggeling L. Response of the central metabolism of Corynebacterium glutamicum to different flux burdens. Biotechnol. Bioeng. 56:1997;168-180.
14. Marx A., Eikmanns B. J., Sahm H., de Graaf A. A., Eggeling L. Response of the central metabolism in Corynebacterium glutamicum to the use of an NADH-dependent glutamate dehydrogenase. Metabolic Engineering. 1:1999;35-48.
15. Mori M., Shiio I. Production of aspartic acid and enzymatic alteration in pyruvate kinase mutants of Brevibacterium flavum. Agric. Biol. Chem. 48:1984;1189-1197.
16. Mori M., Shiio I. Pyruvate formation and sugar metabolism in an amino acid-producing bacterium, Brevibacterium flavum. Agric. Biol. Chem. 51:1987;129-138.
17. Park S. M., Sinskey A. J., Stephanopoulos G. Metabolic and physiological studies of Corynebacterium glutamicum mutants. Biotechnol. Bioeng. 55:1997a;864-879.
18. 13C-NMR spectroscopy and GC-MS. Appl. Microbiol. Biotechnol. 47:1997b;430-440.
19. Peters-Wendisch P. G., Wendisch V. F., de Graaf A. A., Eikmanns B. J., Sahm H. C3-carboxylation as an anaplerotic reaction in phosphoenolpyruvate-deficient Corynebacterium glutamicum. Arch. Microbiol. 165:1996;387-396.
20. Pons A., Dussap C. G., Pequignot C., Gros J. B. Metabolic flux distribution in Corynebacterium glutamicum ATCC 17965 for various carbon sources. Biotechnol. Bioeng. 51:1996;177-189.
21. 13C-NMR studies of Corynebacterium melassecola metabolic pathways. Eur. J. Biochem. 227:1995;488-493.
22. Snoep J. L., Teixeira de Mattos M. J., Starrenburg M., Hugenholtz J. Isolation, characterisation and physiological role of the pyruvate dehydrogenase complex and α-acetolactate synthase of Lactococcus lactis subsp. diacetylactis. J. Bacteriol. 174:1992;4831-4841.
23. 13C NMR studies of the fluxes in the central metabolism of Corynebacterium glutamicum during growth and overproduction of amino acids in batch cultures. Appl. Env. Microbiol. 44:1995;489-495.
24. Sugimoto S., Shiio I. Regulation of glucose 6-phosphate dehydrogenase in brevibacterium flavum. Agric. Biol. Chem. 51:1987a;101-108.
25. Sugimoto S., Shiio I. Regulation of 6-phosphogluconate dehydrogenase in brevibacterium flavum. Agric. Biol. Chem. 51:1987b;1257-1263.
26. Vallino J., Stephanopoulos G. Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction. Biotechnol. Bioeng. 41:1993;633-646.
27. Von der Osten C. H., Gioannetti C., Sinskey A. J. Design of a defined medium for growth of Corynebacterium glutamicum in which citrate facilitates iron uptake. Biotechnol. Lett. 11:1989;11-16.