The antitumour activity of alkylating agents is not correlated with the levels of glutathione, glutathione transferase and O6-alkylguanine-DNA- alkyltransferase of human tumour xenografts

European Journal of Cancer

Volumn 34, Issue 11, 1998, Pages 1749-1755

  D'Incalci, M ^a   Bonfanti, M ^a   Pifferi, A ^a   Mascellani, E ^a   Tagliabue, G ^a   Berger, D ^b   Fiebig, H H ^b  

^a Laboratory of Cancer Pharmacology   (Italy)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

DNA repair; Glutathione; Human tumour; O6 alkylguanine DNA alkyltransferase; Xenografts

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ALKYLATING AGENT; ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; NITROSOUREA DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER INHIBITION; CANCER REGRESSION; CANCER RESISTANCE; COLON CARCINOMA; DNA REPAIR; HUMAN; HUMAN TISSUE; INTRAPERITONEAL DRUG ADMINISTRATION; LUNG SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOMACH CARCINOMA; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR XENOGRAFT;

ALKYL AND ARYL TRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CISPLATIN; COLONIC NEOPLASMS; CYCLOPHOSPHAMIDE; DACARBAZINE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASMS; NITROSOUREA COMPOUNDS; STOMACH NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS;

EID: 0032189167     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(98)00191-9     Document Type: Article

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