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Volumn 43, Issue 1, 1999, Pages 80-85

Modulation of cyclophosphamide activity by o6-alkylguanine-dna alkyltransferase

Author keywords

Alkylating agents; Antineoplastic agents; Cyclophosphamide; Drug resistance; Nitrogen mustard compounds

Indexed keywords

4 HYDROPEROXYCYCLOPHOSPHAMIDE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ACROLEIN; CARMUSTINE; CYCLOPHOSPHAMIDE; PHOSPHORAMIDE MUSTARD;

EID: 0032962702     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050866     Document Type: Article
Times cited : (50)

References (21)
  • 1
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • 1. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248
    • (1976) Anal Biochem , vol.72 , pp. 248
    • Bradford, M.M.1
  • 2
    • 0018742909 scopus 로고
    • The heterotransplantation of human craniopharyngiomas in athymic "nude" mice
    • 2. Bullard DE, Bigner DD (1979) The heterotransplantation of human craniopharyngiomas in athymic "nude" mice. Neurosurgery 4: 308
    • (1979) Neurosurgery , vol.4 , pp. 308
    • Bullard, D.E.1    Bigner, D.D.2
  • 3
    • 0029762815 scopus 로고    scopus 로고
    • DNA repair: Enzymatic mechanisms and relevance to drug response
    • 3. Chaney SG, Sancar A (1996) DNA repair: enzymatic mechanisms and relevance to drug response. J Natl Cancer Inst 88: 1346
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1346
    • Chaney, S.G.1    Sancar, A.2
  • 4
    • 0021319465 scopus 로고
    • 2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde
    • 2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde. Cancer Res 44: 990
    • (1984) Cancer Res , vol.44 , pp. 990
    • Chung, F.-L.1    Young, R.2    Hecht, S.S.3
  • 6
    • 0025196019 scopus 로고
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc Natl Acad Sci USA 87: 5368
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5368
    • Dolan, M.E.1    Moschel, R.C.2    Pegg, A.E.3
  • 7
    • 0025924488 scopus 로고
    • 6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents
    • 6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents. Cancer Res 51: 3367
    • (1991) Cancer Res , vol.51 , pp. 3367
    • Dolan, M.E.1    Mitchell, R.B.2    Mummert, C.3    Moschel, R.C.4    Pegg, A.E.5
  • 8
    • 0029656117 scopus 로고    scopus 로고
    • Repair analysis of 4-hydroperoxycyclophosphamide-induced DNA interstrand crosslinking in the c-myc gene in 4-hydroperoxycyclophosphamide-sensitive and -resistant medulloblastoma cell lines
    • 8. Dong Q, Bullock N, Ali-Osman F, Colvin OM, Bigner DD, Friedman HS (1996) Repair analysis of 4-hydroperoxycyclophosphamide-induced DNA interstrand crosslinking in the c-myc gene in 4-hydroperoxycyclophosphamide-sensitive and -resistant medulloblastoma cell lines. Cancer Chemother Pharmacol 37: 242
    • (1996) Cancer Chemother Pharmacol , vol.37 , pp. 242
    • Dong, Q.1    Bullock, N.2    Ali-Osman, F.3    Colvin, O.M.4    Bigner, D.D.5    Friedman, H.S.6
  • 9
    • 0013524498 scopus 로고    scopus 로고
    • A different DNA repair pathway confers drug resistance to 4-hydroperoxycyclophosphamide (4-HC) in human medulloblastoma D283
    • 9. Dong Q, Bullock N, Johnson S, Colvin OM, Bigner DD, Modrich P, Friedman HS (1997) A different DNA repair pathway confers drug resistance to 4-hydroperoxycyclophosphamide (4-HC) in human medulloblastoma D283. Proc Am Assoc Cancer Res 38: 523
    • (1997) Proc Am Assoc Cancer Res , vol.38 , pp. 523
    • Dong, Q.1    Bullock, N.2    Johnson, S.3    Colvin, O.M.4    Bigner, D.D.5    Modrich, P.6    Friedman, H.S.7
  • 17
    • 0029997217 scopus 로고
    • 6-benzylguanine to killing by N,N′-bis(2-chloroethyl)-N-nitrosourea
    • 6-benzylguanine to killing by N,N′-bis(2-chloroethyl)-N-nitrosourea. Cancer Res 56: 1578
    • (1995) Cancer Res , vol.56 , pp. 1578
    • Loktionova, N.A.1    Pegg, A.E.2
  • 18
    • 0024477946 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase in vivo by pretreatment with antineoplastic agents
    • 6-alkylguanine-DNA alkyltransferase in vivo by pretreatment with antineoplastic agents. Biochem Pharmacol 38: 929
    • (1989) Biochem Pharmacol , vol.38 , pp. 929
    • Meer, L.1    Schold, S.C.2    Kleihues, P.3
  • 19
    • 0025195404 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
    • 6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res 50: 6119
    • (1990) Cancer Res , vol.50 , pp. 6119
    • Pegg, A.E.1
  • 20
    • 0029664534 scopus 로고    scopus 로고
    • Protective effect of O6-methylguanine-DNA methyltransferase on the cytotoxic and recombinogenic activity of different antineoplastic drugs
    • 20. Preuss I, Thust R, Kaina B (1996) Protective effect of O6-methylguanine-DNA methyltransferase on the cytotoxic and recombinogenic activity of different antineoplastic drugs. Int J Cancer 65: 506
    • (1996) Int J Cancer , vol.65 , pp. 506
    • Preuss, I.1    Thust, R.2    Kaina, B.3
  • 21
    • 0021238317 scopus 로고
    • NMR spectroscopic studies of intermediary metabolites of cyclophosphamide. A comprehensive kinetic analysis of the interconversion of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and the concomitant partitioning of aldophosphamide between irreversible fragmentation and reversible conjugation pathways
    • 21. Zon G, Ludeman SM, Brandt JA, Boyd VL, Ozkan G, Egan W, Shao K-L (1984) NMR spectroscopic studies of intermediary metabolites of cyclophosphamide. A comprehensive kinetic analysis of the interconversion of cis-and trans-4-hydroxycyclophosphamide with aldophosphamide and the concomitant partitioning of aldophosphamide between irreversible fragmentation and reversible conjugation pathways. J Med Chem 27: 466
    • (1984) J Med Chem , vol.27 , pp. 466
    • Zon, G.1    Ludeman, S.M.2    Brandt, J.A.3    Boyd, V.L.4    Ozkan, G.5    Egan, W.6    Shao, K.-L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.