Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity

Biochemistry

Volumn 38, Issue 22, 1999, Pages 7346-7354

  Lubetsky, Jodi B ^a   Swope, Melissa ^a   Dealwis, Chris ^a   Blake, Paul ^b   Lolis, Elias ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BAYER CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; ISOMERASE; MACROPHAGE MIGRATION INHIBITION FACTOR; PHENYLPYRUVIC ACID; PROLINE;

ARTICLE; CATALYSIS; CONFORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE; ENZYME SUBUNIT; HYDROGEN BOND; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; GLYCINE; HUMANS; HYDROGEN-ION CONCENTRATION; INTRAMOLECULAR OXIDOREDUCTASES; MACROMOLECULAR SUBSTANCES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; METHIONINE; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHENYLPYRUVIC ACIDS; PROLINE; RECOMBINANT PROTEINS;

EID: 0033153283     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990306m     Document Type: Article

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