메뉴 건너뛰기




Volumn 20, Issue 10, 1999, Pages 715-724

Myocardial dysfunction in sepsis: Mechanisms and therapeutic implications

Author keywords

Myocardial dysfunction; Nitric oxide; Sepsis

Indexed keywords

CORTICOSTEROID; CYTOKINE; FREE RADICAL; HYPERTENSIVE AGENT; INOTROPIC AGENT; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTANOID;

EID: 0033135184     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1053/euhj.1998.1358     Document Type: Review
Times cited : (67)

References (93)
  • 1
    • 0024558652 scopus 로고    scopus 로고
    • The septic syndrome. Definition and clinical implications
    • Balk BA. The septic syndrome. Definition and clinical implications. Crit Care Clinics 1998; 5: 1-8.
    • (1998) Crit Care Clinics , vol.5 , pp. 1-8
    • Balk, B.A.1
  • 3
    • 0026710191 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine (see comments)
    • Bone RC, Balk RA, Cerra FB et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine (see comments). Chest 1992; 101: 1644-55.
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3
  • 4
    • 0026874127 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864-74.
    • (1992) Crit Care Med , vol.20 , pp. 864-874
  • 5
    • 0025303027 scopus 로고
    • Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy
    • see comments
    • Parrillo JE, Parker MM, Natanson C et al. Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy (see comments). Ann Intern Med 1990; 113: 227-42.
    • (1990) Ann Intern Med , vol.113 , pp. 227-242
    • Parrillo, J.E.1    Parker, M.M.2    Natanson, C.3
  • 6
    • 0021279377 scopus 로고
    • Profound but reversible myocardial depression in patients with septic shock
    • Parker MM, Shelhamer JH, Bacharach SL et al. Profound but reversible myocardial depression in patients with septic shock. Ann Intern Med 1984; 100: 483-90.
    • (1984) Ann Intern Med , vol.100 , pp. 483-490
    • Parker, M.M.1    Shelhamer, J.H.2    Bacharach, S.L.3
  • 7
    • 0023607880 scopus 로고
    • Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: Heart rate as an early predictor of prognosis
    • Parker MM, Shelhamer JH, Natanson C, Alling DW, Parrillo JE. Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: Heart rate as an early predictor of prognosis. Crit Care Med 1987; 15: 923-9.
    • (1987) Crit Care Med , vol.15 , pp. 923-929
    • Parker, M.M.1    Shelhamer, J.H.2    Natanson, C.3    Alling, D.W.4    Parrillo, J.E.5
  • 8
    • 0023934409 scopus 로고
    • Depressed left ventricular performance. Response to volume infusion in patients with sepsis and septic shock
    • Ognibene FP, Parker MM, Natanson C, Shelhamer JH, Parrillo JE. Depressed left ventricular performance. Response to volume infusion in patients with sepsis and septic shock. Chest 1988; 93: 903-10.
    • (1988) Chest , vol.93 , pp. 903-910
    • Ognibene, F.P.1    Parker, M.M.2    Natanson, C.3    Shelhamer, J.H.4    Parrillo, J.E.5
  • 9
    • 0001394818 scopus 로고
    • Hall JBS, Wood GA, eds. McGraw-Hill, Inc.
    • Walley KRW. Principles of Critical Care, Vol. 2. In: Hall JBS, Wood GA, eds. McGraw-Hill, Inc., 1992: 1393-1416.
    • (1992) Principles of Critical Care , vol.2 , pp. 1393-1416
    • Walley, K.R.W.1
  • 10
    • 0013508689 scopus 로고
    • Interrelation between cardiac oxygen consumption and coronary blood flow
    • Alella A. Interrelation between cardiac oxygen consumption and coronary blood flow. Am J Physiol 1955; 183: 5703.
    • (1955) Am J Physiol , vol.183 , pp. 5703
    • Alella, A.1
  • 13
  • 14
    • 0023097510 scopus 로고
    • Coronary haemodynamics and myocardial metabolism of lactate, free fatty acids, glucose and ketones in patients with septic shock
    • Dhainaut MD. Coronary haemodynamics and myocardial metabolism of lactate, free fatty acids, glucose and ketones in patients with septic shock. Circulation 1987; 75: 533-41.
    • (1987) Circulation , vol.75 , pp. 533-541
    • Dhainaut, M.D.1
  • 15
    • 0028118993 scopus 로고
    • Myocardial energy metabolism and morphology in a canine model of sepsis
    • Solomon MA, Correa R, Alexander HR et al. Myocardial energy metabolism and morphology in a canine model of sepsis. Am J Physiol 1994; 266: H757-68.
    • (1994) Am J Physiol , vol.266
    • Solomon, M.A.1    Correa, R.2    Alexander, H.R.3
  • 17
    • 0027383809 scopus 로고
    • Free radicals and antioxidants in sepsis
    • Goode HF, Webster NR. Free radicals and antioxidants in sepsis. Crit Care Med 1993; 21: 1770-6.
    • (1993) Crit Care Med , vol.21 , pp. 1770-1776
    • Goode, H.F.1    Webster, N.R.2
  • 18
    • 0028927044 scopus 로고
    • Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunction
    • Goode HFC, Walker HC, Howdle BE, Webster PD. Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunction. Crit Care Med 1995; 23: 646-51.
    • (1995) Crit Care Med , vol.23 , pp. 646-651
    • Goode, H.F.C.1    Walker, H.C.2    Howdle, B.E.3    Webster, P.D.4
  • 19
    • 0031033903 scopus 로고    scopus 로고
    • The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock
    • Zingarelli B, Day BJ, Crapo JD, Salzman AL, Szabo C. The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock. Br J Pharmacol 1997; 120: 259-67.
    • (1997) Br J Pharmacol , vol.120 , pp. 259-267
    • Zingarelli, B.1    Day, B.J.2    Crapo, J.D.3    Salzman, A.L.4    Szabo, C.5
  • 20
    • 0030203367 scopus 로고    scopus 로고
    • The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury
    • Szabo C. The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. Shock 1996; 6: 79-88.
    • (1996) Shock , vol.6 , pp. 79-88
    • Szabo, C.1
  • 21
    • 0000934822 scopus 로고
    • Myocardial depression in shock. A survey of cardiodynamic studies
    • Wiggers CJ. Myocardial depression in shock. A survey of cardiodynamic studies. Am Heart J 1947; 33: 633-50.
    • (1947) Am Heart J , vol.33 , pp. 633-650
    • Wiggers, C.J.1
  • 22
    • 0022409016 scopus 로고
    • A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performance
    • Parrillo JE, Burch C, Shelhamer JH, Parker MM, Natanson C, Schuette W. A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performance. J Clin Invest 1985; 76: 1539-53.
    • (1985) J Clin Invest , vol.76 , pp. 1539-1553
    • Parrillo, J.E.1    Burch, C.2    Shelhamer, J.H.3    Parker, M.M.4    Natanson, C.5    Schuette, W.6
  • 23
    • 0024371424 scopus 로고
    • A circulating myocardial depressant substance is associated with cardiac dysfunction and peripheral hypoperfusion (lactic acidemia) in patients with septic shock
    • see comments
    • Reilly JM, Cunnion RE, Burch-Whitman C, Parker MM, Shelhamer JH, Parrillo JE. A circulating myocardial depressant substance is associated with cardiac dysfunction and peripheral hypoperfusion (lactic acidemia) in patients with septic shock (see comments). Chest 1989; 95: 1072-80.
    • (1989) Chest , vol.95 , pp. 1072-1080
    • Reilly, J.M.1    Cunnion, R.E.2    Burch-Whitman, C.3    Parker, M.M.4    Shelhamer, J.H.5    Parrillo, J.E.6
  • 24
    • 0029975877 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum
    • Kumar A, Thota V, Dee L, Olson J, Uretz E, Parrillo JE. Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum. J Exp Med 1996; 183: 949-58.
    • (1996) J Exp Med , vol.183 , pp. 949-958
    • Kumar, A.1    Thota, V.2    Dee, L.3    Olson, J.4    Uretz, E.5    Parrillo, J.E.6
  • 25
    • 0024342856 scopus 로고
    • The cardiovascular response of normal humans to the administration of endotoxin
    • see comments
    • Suffredini AF, Fromm RE, Parker MM et al. The cardiovascular response of normal humans to the administration of endotoxin (see comments). N Engl J Med 1989; 321: 280-7.
    • (1989) N Engl J Med , vol.321 , pp. 280-287
    • Suffredini, A.F.1    Fromm, R.E.2    Parker, M.M.3
  • 26
    • 0030974305 scopus 로고    scopus 로고
    • Leukocytes and decreased left-ventricular contractility during endotoxaemia in rabbits
    • Granton JTG, Allard CM, van Eden MF, Walley S. Leukocytes and decreased left-ventricular contractility during endotoxaemia in rabbits. Am J Crit Care Med 1997; 155: 1977-83.
    • (1997) Am J Crit Care Med , vol.155 , pp. 1977-1983
    • Granton, J.T.G.1    Allard, C.M.2    Van Eden, M.F.3    Walley, S.4
  • 27
    • 4243292979 scopus 로고    scopus 로고
    • Activated neutrophils adhere to and decrease fractional shortening of activated rat cardiac myocytes
    • Abstr.
    • Walley KRS, Poon BY. Activated neutrophils adhere to and decrease fractional shortening of activated rat cardiac myocytes (Abstr). Am J Resp Crit Care Med 1998; 157: A103.
    • (1998) Am J Resp Crit Care Med , vol.157
    • Walley, K.R.S.1    Poon, B.Y.2
  • 28
    • 0026508075 scopus 로고
    • Administration of anti-TNF antibody improves left ventricular function in septic shock patients
    • Vincent J-LB, Marecaux J. Administration of anti-TNF antibody improves left ventricular function in septic shock patients. Chest 1992; 101: 810-15.
    • (1992) Chest , vol.101 , pp. 810-815
    • Vincent, J.-L.B.1    Marecaux, J.2
  • 30
    • 0029923087 scopus 로고    scopus 로고
    • Differential regulation of cyclo-oxygenase-1 and cyclo-oxygenase-2 gene expression by lipopolysaccharide treatment in vivo in the rat
    • Liu SF, Newton R, Evans TW, Barnes PJ. Differential regulation of cyclo-oxygenase-1 and cyclo-oxygenase-2 gene expression by lipopolysaccharide treatment in vivo in the rat. Clin Sci Colch 1996; 90: 301-6.
    • (1996) Clin Sci Colch , vol.90 , pp. 301-306
    • Liu, S.F.1    Newton, R.2    Evans, T.W.3    Barnes, P.J.4
  • 31
    • 0019986518 scopus 로고
    • Plasma thromboxane concentrations are raised in patients dying with septic shock
    • Reines HDH, Cook PV, Wise JA, Rambo WC. Plasma thromboxane concentrations are raised in patients dying with septic shock. Lancet 1982; 8291: 174-5.
    • (1982) Lancet , vol.8291 , pp. 174-175
    • Reines, H.D.H.1    Cook, P.V.2    Wise, J.A.3    Rambo, W.C.4
  • 32
    • 0030950128 scopus 로고    scopus 로고
    • Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat sorta in organ culture
    • Bishop-Bailey DL, Warner SW, Chen TD, Mitchell G. Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat sorta in organ culture. Bri J Pharmacol 1997; 121: 125-33.
    • (1997) Bri J Pharmacol , vol.121 , pp. 125-133
    • Bishop-Bailey, D.L.1    Warner, S.W.2    Chen, T.D.3    Mitchell, G.4
  • 33
    • 0028240645 scopus 로고
    • The nitric oxide synthase family of proteins
    • Sessa WC. The nitric oxide synthase family of proteins. J Vasc Res 1994; 31: 131-43.
    • (1994) J Vasc Res , vol.31 , pp. 131-143
    • Sessa, W.C.1
  • 34
    • 0027466192 scopus 로고
    • Nitric oxide and the control of human vascular tone in health and disease
    • Calver AC, Vallance J. Nitric oxide and the control of human vascular tone in health and disease. Eur J Med 1993; 2: 48-53.
    • (1993) Eur J Med , vol.2 , pp. 48-53
    • Calver, A.C.1    Vallance, J.2
  • 35
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992; 12: 3051-64.
    • (1992) FASEB J , vol.12 , pp. 3051-3064
    • Nathan, C.1
  • 36
    • 0025011716 scopus 로고
    • Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
    • Rees DD, Palmer RM, Schulz R, Hodson HF, Moncada S. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 1990; 101: 746-52.
    • (1990) Br J Pharmacol , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.2    Schulz, R.3    Hodson, H.F.4    Moncada, S.5
  • 37
    • 0029091366 scopus 로고
    • Nitric oxide and its role in the cardiovascular system
    • Loscalzo JW. Nitric oxide and its role in the cardiovascular system. Prog Cardiovasc Dis 1995; 38: 87-104.
    • (1995) Prog Cardiovasc Dis , vol.38 , pp. 87-104
    • Loscalzo, J.W.1
  • 38
    • 0027225229 scopus 로고
    • Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium
    • Balligand JLU, Kelly D, Kobzik RA et al. Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J Clin Invest 1993; 91: 2314-19.
    • (1993) J Clin Invest , vol.91 , pp. 2314-2319
    • Balligand, J.L.U.1    Kelly, D.2    Kobzik, R.A.3
  • 39
    • 0027053340 scopus 로고
    • Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia
    • Brady AJ, Poole-Wilson PA, Harding SE, Warren JB. Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. Am J Physiol 1992; 263: H1963-6.
    • (1992) Am J Physiol , vol.263
    • Brady, A.J.1    Poole-Wilson, P.A.2    Harding, S.E.3    Warren, J.B.4
  • 40
    • 0028105595 scopus 로고
    • Myocardial relaxant effect of exogenous nitric oxide in isolated ejecting hearts
    • Grocott-Mason R, Fort S, Lewis MJ, Shah AM. Myocardial relaxant effect of exogenous nitric oxide in isolated ejecting hearts. Am J Physiol 1994; 266: H1699-705.
    • (1994) Am J Physiol , vol.266
    • Grocott-Mason, R.1    Fort, S.2    Lewis, M.J.3    Shah, A.M.4
  • 41
    • 0028896285 scopus 로고
    • Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-dependent protein kinase
    • Wahler GMD. Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-dependent protein kinase. Am J Physiol 1995; 261: C45-C54.
    • (1995) Am J Physiol , vol.261
    • Wahler, G.M.D.1
  • 42
    • 0028293196 scopus 로고
    • 8-bromo-cGMP reduces the myofilament response to Ca2+ in intact cardiac myocytes
    • Shah AM, Spurgeon HA, Sollott SJ, Talo A, Lakatta EG. 8-bromo-cGMP reduces the myofilament response to Ca2+ in intact cardiac myocytes. Circ Res 1994; 74: 970-8.
    • (1994) Circ Res , vol.74 , pp. 970-978
    • Shah, A.M.1    Spurgeon, H.A.2    Sollott, S.J.3    Talo, A.4    Lakatta, E.G.5
  • 43
    • 0028275822 scopus 로고
    • Novel cardiac myofilament desensitizing factor released by endocardial and vascular endothelial cells
    • Shah AM, Mebazaa A, Wetzel RC, Lakatta EG. Novel cardiac myofilament desensitizing factor released by endocardial and vascular endothelial cells. Circulation 1994; 89: 2492-7.
    • (1994) Circulation , vol.89 , pp. 2492-2497
    • Shah, A.M.1    Mebazaa, A.2    Wetzel, R.C.3    Lakatta, E.G.4
  • 44
    • 0025921701 scopus 로고
    • Cyclic AMP phosphodiesterases and calcium current regulation in cardiac cells
    • Fischmeister RH. Cyclic AMP phosphodiesterases and calcium current regulation in cardiac cells. Life Sci 1991; 48: 2365-76.
    • (1991) Life Sci , vol.48 , pp. 2365-2376
    • Fischmeister, R.H.1
  • 45
    • 0027947675 scopus 로고
    • New insights into the regulation of inducible nitric oxide synthesis
    • Morris SMB. New insights into the regulation of inducible nitric oxide synthesis. Am J Physiol 1994; 266: E829-39.
    • (1994) Am J Physiol , vol.266
    • Morris, S.M.B.1
  • 46
    • 0028288342 scopus 로고
    • Inducible nitric oxide synthase in vascular smooth muscle
    • Schini VBB, Vanhoutte R. Inducible nitric oxide synthase in vascular smooth muscle. Arzneimittelforschung 1994; 44: 432-5.
    • (1994) Arzneimittelforschung , vol.44 , pp. 432-435
    • Schini, V.B.B.1    Vanhoutte, R.2
  • 47
    • 0028135094 scopus 로고
    • Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro
    • Balligand JL, Ungureanu-Longrois D, Simmons WW et al. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro. J Biol Chem 1994; 269: 27580-8.
    • (1994) J Biol Chem , vol.269 , pp. 27580-27588
    • Balligand, J.L.1    Ungureanu-Longrois, D.2    Simmons, W.W.3
  • 48
    • 0027994241 scopus 로고
    • Cellular localization of inducible nitric oxide synthase in experimental endotoxic shock in the rat
    • Cook HTB, Jansen AJ, Taylor AS, Loi GM, Cattell RK. Cellular localization of inducible nitric oxide synthase in experimental endotoxic shock in the rat. Clini Sci 1994; 87: 179-86.
    • (1994) Clini Sci , vol.87 , pp. 179-186
    • Cook, H.T.B.1    Jansen, A.J.2    Taylor, A.S.3    Loi, G.M.4    Cattell, R.K.5
  • 49
    • 0030026515 scopus 로고    scopus 로고
    • Peroxynitrite-mediated DNA strand breakage activates polyadenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide
    • Zingarelli B, Wong Ocmh, Salzman AL, Szabo C. Peroxynitrite-mediated DNA strand breakage activates polyadenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J Immunol 1996; 156: 350-8.
    • (1996) J Immunol , vol.156 , pp. 350-358
    • Zingarelli, B.1    Ocmh, W.2    Salzman, A.L.3    Szabo, C.4
  • 50
    • 0031066766 scopus 로고    scopus 로고
    • Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells
    • Szabo C, Saunders C, Salzman Ocmal. Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells. Am J Respir Cell Mol Biol 1997; 16: 105-9.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 105-109
    • Szabo, C.1    Saunders, C.2    Ocmal, S.3
  • 51
    • 0027165355 scopus 로고
    • Effects of the xanthine oxidase system on cardiac function in anaesthetised rats
    • Laycock SK, McMurray J, Kane KA, Parratt JR. Effects of the xanthine oxidase system on cardiac function in anaesthetised rats. Free Radic Biol Med 1993; 15: 249-55.
    • (1993) Free Radic Biol Med , vol.15 , pp. 249-255
    • Laycock, S.K.1    McMurray, J.2    Kane, K.A.3    Parratt, J.R.4
  • 52
    • 0031009490 scopus 로고    scopus 로고
    • Peroxynitrite, the product of nitric oxide and superoxide, causes myocardial injury in the isolated perfused rat heart
    • Lopez BLL, Xhristopher GL, Ma TA. Peroxynitrite, the product of nitric oxide and superoxide, causes myocardial injury in the isolated perfused rat heart. Cor Art Dis 1997; 8: 149-53.
    • (1997) Cor Art Dis , vol.8 , pp. 149-153
    • Lopez, B.L.L.1    Xhristopher, G.L.2    Ma, T.A.3
  • 53
    • 0023905907 scopus 로고
    • Effects of damaging the endocardial surface on the mechanical performance of isolated cardiac muscle
    • Brutsaert DLM, Sipido AL. Effects of damaging the endocardial surface on the mechanical performance of isolated cardiac muscle. Circ Res 1988; 62: 358-66.
    • (1988) Circ Res , vol.62 , pp. 358-366
    • Brutsaert, D.L.M.1    Sipido, A.L.2
  • 54
    • 0013508491 scopus 로고
    • Positive inotropic effects of acetylcholine; Role of the endocardial endothelium
    • Mohan PB. Positive inotropic effects of acetylcholine; Role of the endocardial endothelium. Circulation 1994; 90: 1649.
    • (1994) Circulation , vol.90 , pp. 1649
    • Mohan, P.B.1
  • 55
    • 0025054404 scopus 로고
    • Role of endocardial endothelium in positive inotropic effect of vasopressin
    • Schoemaker IEM, Andries AL, Brutsaert LJ. Role of endocardial endothelium in positive inotropic effect of vasopressin. Am J Physiol 1990; 259: H1148-H1151.
    • (1990) Am J Physiol , vol.259
    • Schoemaker, I.E.M.1    Andries, A.L.2    Brutsaert, L.J.3
  • 56
    • 0025122670 scopus 로고
    • Endocardial endothelium mediated positive inotropic response to alpha 1-adrenoceptor agonist in mammalian heart
    • Meulemans ALA, Brutsaert LJ. Endocardial endothelium mediated positive inotropic response to alpha 1-adrenoceptor agonist in mammalian heart. Mol Cell Cardiol 1990; 22: 667-85.
    • (1990) Mol Cell Cardiol , vol.22 , pp. 667-685
    • Meulemans, A.L.A.1    Brutsaert, L.J.2
  • 57
    • 0029940216 scopus 로고    scopus 로고
    • Paracrine modulation of heart cell function by endothelial cells
    • Shah AM. Paracrine modulation of heart cell function by endothelial cells. Cardiovasc Res 1996; 31: 847-67.
    • (1996) Cardiovasc Res , vol.31 , pp. 847-867
    • Shah, A.M.1
  • 58
    • 0026486348 scopus 로고
    • The endocardial endothelium
    • Brutsaert DLA. The endocardial endothelium. Am J Physiol 1992; 263: H985-1002.
    • (1992) Am J Physiol , vol.263
    • Brutsaert, D.L.A.1
  • 59
    • 0027465184 scopus 로고
    • Response of critically ill patients to treatment aimed at achieving supranormal oxygen delivery and consumption. Relationship to outcome_rfsti Chest
    • see comments
    • Hayes MA, Yau EH, Timmins AC, Hinds CJ, Watson D. Response of critically ill patients to treatment aimed at achieving supranormal oxygen delivery and consumption. Relationship to outcome (see comments). Chest 1993; 103: 886-95.
    • (1993) , vol.103 , pp. 886-895
    • Hayes, M.A.1    Yau, E.H.2    Timmins, A.C.3    Hinds, C.J.4    Watson, D.5
  • 60
    • 0001814561 scopus 로고    scopus 로고
    • Use and misuse of catecholamines: Combination in septic shock patients
    • Vincent J-L, ed. Springer
    • Martin CV, Potie X. Use and misuse of catecholamines: Combination in septic shock patients. In: Vincent J-L, ed. Yearbook Of Intensive Care and Emergency Medicine. Springer, 1997: 289-301.
    • (1997) Yearbook of Intensive Care and Emergency Medicine , pp. 289-301
    • Martin, C.V.1    Potie, X.2
  • 61
    • 0024590550 scopus 로고
    • Monophosphoryl lipid A blocks the hemodynamic effects of lethal endotoxemia
    • Rackow EC, Astiz ME, Kim YB, Weil MH. Monophosphoryl lipid A blocks the hemodynamic effects of lethal endotoxemia. J Lab Clin Med 1989; 113: 112-17.
    • (1989) J Lab Clin Med , vol.113 , pp. 112-117
    • Rackow, E.C.1    Astiz, M.E.2    Kim, Y.B.3    Weil, M.H.4
  • 62
    • 0026092964 scopus 로고
    • Monophosphoryl lipid A induces tolerance to the lethal hemodynamic effects of endotoxemia
    • Astiz ME, Rackow EC, Kim YB, Weil MH. Monophosphoryl lipid A induces tolerance to the lethal hemodynamic effects of endotoxemia. Circ Shock 1991; 33: 92-7.
    • (1991) Circ Shock , vol.33 , pp. 92-97
    • Astiz, M.E.1    Rackow, E.C.2    Kim, Y.B.3    Weil, M.H.4
  • 64
    • 0026016470 scopus 로고
    • Treatment of Gram-negative bacteraemia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomised, double-blind, placebo-controlled trial
    • Ziegler EJC, Fisher J, Sprung CJ. Treatment of Gram-negative bacteraemia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomised, double-blind, placebo-controlled trial. N Engl J Med 1991; 324: 429-436.
    • (1991) N Engl J Med , vol.324 , pp. 429-436
    • Ziegler, E.J.C.1    Fisher, J.2    Sprung, C.J.3
  • 65
    • 0017064383 scopus 로고
    • Steroids in the treatment of septic shock
    • Shumer W. Steroids in the treatment of septic shock. Ann Surg 1976; 184: 333-41.
    • (1976) Ann Surg , vol.184 , pp. 333-341
    • Shumer, W.1
  • 66
  • 68
    • 8044246571 scopus 로고    scopus 로고
    • The effects of ibuprofen on the physiology and survival of patients with sepsis. The ibuprofen in sepsis study group
    • Bernard GRW, Russell AP, Schien JA et al. The effects of ibuprofen on the physiology and survival of patients with sepsis. The ibuprofen in sepsis study group. N Eng J Med 1997; 336: 912-18.
    • (1997) N Eng J Med , vol.336 , pp. 912-918
    • Bernard, G.R.W.1    Russell, A.P.2    Schien, J.A.3
  • 69
    • 0025911402 scopus 로고
    • The effect of inhibitors of the L-arginine/nitric oxide pathway on endotoxin-induced loss of vascular responsiveness in anaesthetized rats
    • Gray GA, Schott C, Julou Schaeffer G, Fleming I, Parratt JR, Stoclet JC. The effect of inhibitors of the L-arginine/nitric oxide pathway on endotoxin-induced loss of vascular responsiveness in anaesthetized rats. Br J Pharmacol 1991; 103: 1218-24.
    • (1991) Br J Pharmacol , vol.103 , pp. 1218-1224
    • Gray, G.A.1    Schott, C.2    Julou Schaeffer, G.3    Fleming, I.4    Parratt, J.R.5    Stoclet, J.C.6
  • 70
    • 0027103683 scopus 로고
    • The role of nitric oxide in endotoxic shock: Effects of NG-monomethyl-L-arginine
    • Nava E, Palmer RM, Moncada S. The role of nitric oxide in endotoxic shock: Effects of NG-monomethyl-L-arginine. J Cardiovasc Pharmacol 1992; 20 Suppl 12: S132-4.
    • (1992) J Cardiovasc Pharmacol , vol.20 , Issue.SUPPL. 12
    • Nava, E.1    Palmer, R.M.2    Moncada, S.3
  • 71
    • 0028577721 scopus 로고
    • Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase
    • Szabo C, Southan GJ, Thiemermann C. Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. Proc Natl Acad Sci U.S.A. 1994; 91: 12472-6.
    • (1994) Proc Natl Acad Sci U.S.A. , vol.91 , pp. 12472-12476
    • Szabo, C.1    Southan, G.J.2    Thiemermann, C.3
  • 72
    • 0029931337 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition versus norepinephrine for the treatment of hyperdynamic sepsis in sheep
    • Booke M, Hinder F, McGuire R, Traber LD, Traber DL. Nitric oxide synthase inhibition versus norepinephrine for the treatment of hyperdynamic sepsis in sheep. Crit Care Med 1996; 24: 835-44.
    • (1996) Crit Care Med , vol.24 , pp. 835-844
    • Booke, M.1    Hinder, F.2    McGuire, R.3    Traber, L.D.4    Traber, D.L.5
  • 73
    • 0028855814 scopus 로고
    • Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock
    • Klemm P, Thiemermann C, Winklmaier G, Martorana PA, Henning R. Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock. Br J Pharmacol 1995; 114: 363-8.
    • (1995) Br J Pharmacol , vol.114 , pp. 363-368
    • Klemm, P.1    Thiemermann, C.2    Winklmaier, G.3    Martorana, P.A.4    Henning, R.5
  • 74
    • 0026346162 scopus 로고
    • Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock
    • see comments
    • Petros A, Bennett D, Vallance P. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock [see comments]. Lancet 1991; 338: 1557-8.
    • (1991) Lancet , vol.338 , pp. 1557-1558
    • Petros, A.1    Bennett, D.2    Vallance, P.3
  • 75
    • 0013477756 scopus 로고
    • Inhibition of NO synthesis in septic shock
    • Geroulanos SS, Cakmacki J. Inhibition of NO synthesis in septic shock. Lancet 1992; 15: 339-435.
    • (1992) Lancet , vol.15 , pp. 339-435
    • Geroulanos, S.S.1    Cakmacki, J.2
  • 77
    • 0028872983 scopus 로고
    • Methylene blue administration in septic shock: A clinical trial
    • Preiser LP, Roman J-C, Carlier A et al. Methylene blue administration in septic shock: A clinical trial. Crit Care Med 1995; 23: 259-64.
    • (1995) Crit Care Med , vol.23 , pp. 259-264
    • Preiser, L.P.1    Roman, J.-C.2    Carlier, A.3
  • 78
    • 0025943512 scopus 로고
    • Recombinant soluble TNF receptor proteins protect mice from LPS-induced lethality
    • Lessauer W. Recombinant soluble TNF receptor proteins protect mice from LPS-induced lethality. Eur J Immunol 1991; 156: 2883-6.
    • (1991) Eur J Immunol , vol.156 , pp. 2883-2886
    • Lessauer, W.1
  • 79
    • 13344270905 scopus 로고    scopus 로고
    • Protection against lethal E. Coli bacteremia in baboons by pretreatment with 55-kDa TNF receptor (CD 120a)-Ig fusion protein, Ro 45-2981
    • Van Zee KJ. Protection against lethal E. Coli bacteremia in baboons by pretreatment with 55-kDa TNF receptor (CD 120a)-Ig fusion protein, Ro 45-2981. J Immunol 1996; 156: 2221-30.
    • (1996) J Immunol , vol.156 , pp. 2221-2230
    • Van Zee, K.J.1
  • 80
    • 0032495658 scopus 로고    scopus 로고
    • Double-blind randomized controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock
    • Abraham EA, Gutierrez A, Tessler G. Double-blind randomized controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock. Lancet 1998; 351: 929-33.
    • (1998) Lancet , vol.351 , pp. 929-933
    • Abraham, E.A.1    Gutierrez, A.2    Tessler, G.3
  • 81
    • 0029835023 scopus 로고    scopus 로고
    • INTERSEPT: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis
    • International Sepsis Trial Study Group
    • Cohen JC. INTERSEPT: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis. International Sepsis Trial Study Group. Crit Care Med 1996; 24: 1431-40.
    • (1996) Crit Care Med , vol.24 , pp. 1431-1440
    • Cohen, J.C.1
  • 82
    • 0000406196 scopus 로고
    • Myocardial cell contractility is depressed by supernatants of endotoxin stimulated THP-1 cells
    • Kumar AK, Ginsburg R. Myocardial cell contractility is depressed by supernatants of endotoxin stimulated THP-1 cells. Crit Care Med 1994; 22: A118.
    • (1994) Crit Care Med , vol.22
    • Kumar, A.K.1    Ginsburg, R.2
  • 83
    • 0028288683 scopus 로고
    • Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans. Assessment by bicoronary sodium nitroprusside infusion
    • Paulus WJ, Vantrimpont PJ, Shah AM. Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans. Assessment by bicoronary sodium nitroprusside infusion. Circulation 1994; 89: 2070-8.
    • (1994) Circulation , vol.89 , pp. 2070-2078
    • Paulus, W.J.1    Vantrimpont, P.J.2    Shah, A.M.3
  • 84
    • 0026585007 scopus 로고
    • Anti-tumor necrosis factor antibody therapy fails to prevent lethality after cecal ligation and puncture or endotoxemia
    • Eskandari MK, Bolgos G, Miller C, Nguyen DT, DeForge LE, Remick DG. Anti-tumor necrosis factor antibody therapy fails to prevent lethality after cecal ligation and puncture or endotoxemia. J Immunol 1992; 148: 2724-30.
    • (1992) J Immunol , vol.148 , pp. 2724-2730
    • Eskandari, M.K.1    Bolgos, G.2    Miller, C.3    Nguyen, D.T.4    DeForge, L.E.5    Remick, D.G.6
  • 85
    • 0024469951 scopus 로고
    • Effect of antioxidants in experimental escherichia coli septicemia
    • Broner CW, Shenep JL, Stidham GL et al. Effect of antioxidants in experimental escherichia coli septicemia. Circ Shock 1989; 29: 77-92.
    • (1989) Circ Shock , vol.29 , pp. 77-92
    • Broner, C.W.1    Shenep, J.L.2    Stidham, G.L.3
  • 86
    • 0023073281 scopus 로고
    • Inhibition of lipid peroxidation improves survival rate of endotoxaemic rats
    • Kunimoto FM, Ogawa T, Fujita R. Inhibition of lipid peroxidation improves survival rate of endotoxaemic rats. Circ Shock 1987; 21: 15-22.
    • (1987) Circ Shock , vol.21 , pp. 15-22
    • Kunimoto, F.M.1    Ogawa, T.2    Fujita, R.3
  • 87
    • 0030859188 scopus 로고    scopus 로고
    • The effects of antioxidants in patients with septic shock
    • Galley HF. The effects of antioxidants in patients with septic shock. Free Rad Biol Med 1997; 23: 768-74.
    • (1997) Free Rad Biol Med , vol.23 , pp. 768-774
    • Galley, H.F.1
  • 88
    • 0030824131 scopus 로고    scopus 로고
    • Selenium administration in patients with sepsis syndrome. A prospective randomized study
    • Zimmermann TA, Kuhne S, Vogelsang H, Grutzmann U, Kopprasch R. Selenium administration in patients with sepsis syndrome. A prospective randomized study. Med Klin 1997; 92: 3-4.
    • (1997) Med Klin , vol.92 , pp. 3-4
    • Zimmermann, T.A.1    Kuhne, S.2    Vogelsang, H.3    Grutzmann, U.4    Kopprasch, R.5
  • 89
    • 0028117232 scopus 로고
    • Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo
    • Szabo C, Thiemermann C, Wu CC, Perretti M, Vane JR. Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. Proc Natl Acad Sci U.S.A. 1994; 91: 271-5.
    • (1994) Proc Natl Acad Sci U.S.A. , vol.91 , pp. 271-275
    • Szabo, C.1    Thiemermann, C.2    Wu, C.C.3    Perretti, M.4    Vane, J.R.5
  • 91
    • 0013508493 scopus 로고
    • Septic shock co-operative
    • Septic shock co-operative. N Engl J Med 1987; 317: 650.
    • (1987) N Engl J Med , vol.317 , pp. 650
  • 92
    • 0023252009 scopus 로고
    • A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock
    • Bone RC, Fisher Jr CJ, Clemmer TP, Slotman GJ, Metz CA, Balk RA. A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N Engl J Med 1987; 317: 653-8.
    • (1987) N Engl J Med , vol.317 , pp. 653-658
    • Bone, R.C.1    Fisher C.J., Jr.2    Clemmer, T.P.3    Slotman, G.J.4    Metz, C.A.5    Balk, R.A.6
  • 93
    • 0021714681 scopus 로고
    • Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis
    • Fink MP, MacVittie TJ, Casey LC. Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis. Ann Surg 1984; 200: 619-26.
    • (1984) Ann Surg , vol.200 , pp. 619-626
    • Fink, M.P.1    MacVittie, T.J.2    Casey, L.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.