-
1
-
-
0024405827
-
The biology of cachectin/TNF: A primary mediator of the host response
-
Beutler, B., and A. Cerami. 1989. The biology of cachectin/TNF: a primary mediator of the host response. Annu Rev Immunol. 7:625.
-
(1989)
Annu Rev Immunol.
, vol.7
, pp. 625
-
-
Beutler, B.1
Cerami, A.2
-
3
-
-
0026717674
-
The pathophysiology of tumor necrosis factors
-
Vassalh, P. 1992. The pathophysiology of tumor necrosis factors Annu. Rev. Immunol. 10:411.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 411
-
-
Vassalh, P.1
-
4
-
-
0023912918
-
Cytokine appearance in human endotoxemia and primate bacteremia
-
Hesse, D. G., K. J. Tracey, Y Fong, K. R. Manogue, M. A. Palladino, A. Cerami, G. T. Shires, and S. F. Lowry. 1988. Cytokine appearance in human endotoxemia and primate bacteremia. Surg Gynecol. Obstet. 166:147.
-
(1988)
Surg Gynecol. Obstet.
, vol.166
, pp. 147
-
-
Hesse, D.G.1
Tracey, K.J.2
Fong, Y.3
Manogue, K.R.4
Palladino, M.A.5
Cerami, A.6
Shires, G.T.7
Lowry, S.F.8
-
5
-
-
0023893831
-
Detection of circulating tumor necrosis factor after endotoxin administration
-
Michie, H R., K. R. Manogue, D. R Spriggs, A. Revhaug, S. O'Dwyer, C. A. Dinarello, A Cerami, S. M. Wolff, and D. W. Willmore. 1988 Detection of circulating tumor necrosis factor after endotoxin administration. N. Engl. J. Med. 318.1481.
-
(1988)
N. Engl. J. Med.
, vol.318
, pp. 1481
-
-
Michie, H.R.1
Manogue, K.R.2
Spriggs, D.R.3
Revhaug, A.4
O'Dwyer, S.5
Dinarello, C.A.6
Cerami, A.7
Wolff, S.M.8
Willmore, D.W.9
-
6
-
-
0025358130
-
The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans
-
Fong, Y., M. A. Marano, L. L. Moldawer, H. Wei, S E. Calvano, J S. Kenney, A. C. Allison, A Cerami, G T. Shires, and S F. Lowry. 1990. The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans. J. Clin. Invest. 85.1896.
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 1896
-
-
Fong, Y.1
Marano, M.A.2
Moldawer, L.L.3
Wei, H.4
Calvano, S.E.5
Kenney, J.S.6
Allison, A.C.7
Cerami, A.8
Shires, G.T.9
Lowry, S.F.10
-
7
-
-
0025647250
-
Experimental endotoxemia in humans, analysis of cytokine release and coagulation, fibrinolytic and complement pathways
-
van Deventer, S. J. H., H. R. Buller, J W. ten Cate, L A. Aarden, C. E. Hack, and A. Sturk. 1990. Experimental endotoxemia in humans, analysis of cytokine release and coagulation, fibrinolytic and complement pathways Blood 76.2520.
-
(1990)
Blood
, vol.76
, pp. 2520
-
-
Van Deventer, S.J.H.1
Buller, H.R.2
Ten Cate, J.W.3
Aarden, L.A.4
Hack, C.E.5
Sturk, A.6
-
8
-
-
0025909315
-
IL-8 in septic shock, endotoxemia and following IL-1 administration
-
van Zee, K., L. deForge, E. Fischer, M A Marano, J. S. Kenney, D G. Remick, S. F. Lowry, and L L Moldawer. 1991. IL-8 in septic shock, endotoxemia and following IL-1 administration J. Immunol 146 3478.
-
(1991)
J. Immunol
, vol.146
, pp. 3478
-
-
Van Zee, K.1
DeForge, L.2
Fischer, E.3
Marano, M.A.4
Kenney, J.S.5
Remick, D.G.6
Lowry, S.F.7
Moldawer, L.L.8
-
9
-
-
0023028369
-
Shock and tissue injury induced by recombinant human cachectin
-
Tracey, K., B. R. Beutler, S. F. Lowry, J Merryweather, S. Wolpe, I. W. Milsark, R J Hanri, T. J Fahey, A. Zentella, J. D Albert, G. T Shires, and A. Cerami. 1986. Shock and tissue injury induced by recombinant human cachectin. Science 234:470
-
(1986)
Science
, vol.234
, pp. 470
-
-
Tracey, K.1
Beutler, B.R.2
Lowry, S.F.3
Merryweather, J.4
Wolpe, S.5
Milsark, I.W.6
Hanri, R.J.7
Fahey, T.J.8
Zentella, A.9
Albert, J.D.10
Shires, G.T.11
Cerami, A.12
-
10
-
-
0023183621
-
Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog
-
Tracey, K , S. F. Lowry, T. J. Fahey, J. D Albert, Y Fong, D. Hesse, B R Beutler, K. R. Manogue, S Calvano, H. Wei, A Cerami, and G. T. Shires 1987. Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog Surg Gynecol. Obstet 164 415.
-
(1987)
Surg Gynecol. Obstet
, vol.164
, pp. 415
-
-
Tracey, K.1
Lowry, S.F.2
Fahey, T.J.3
Albert, J.D.4
Fong, Y.5
Hesse, D.6
Beutler, B.R.7
Manogue, K.R.8
Calvano, S.9
Wei, H.10
Cerami, A.11
Shires, G.T.12
-
11
-
-
0027214907
-
Interleukin-8 release in baboon septicemia is partially dependent on tumor necrosis factor
-
Redl, H., G. Schlag, M. Ceska, J. Davies, and W. A. Buurman. 1993. Interleukin-8 release in baboon septicemia is partially dependent on tumor necrosis factor. J. Infect Dis. 167:1464
-
(1993)
J. Infect Dis.
, vol.167
, pp. 1464
-
-
Redl, H.1
Schlag, G.2
Ceska, M.3
Davies, J.4
Buurman, W.A.5
-
12
-
-
0028675581
-
Big-endothelin release in baboon bacteremia is partially TNF dependent
-
Redl, H , G. Schlag, S. Bahrami, R. Kargl, W. Hartter, W. Woloszczuk, and J Davies. 1994 Big-endothelin release in baboon bacteremia is partially TNF dependent. J. Lab. Clin. Med. 124.796
-
(1994)
J. Lab. Clin. Med.
, vol.124
, pp. 796
-
-
Redl, H.1
Schlag, G.2
Bahrami, S.3
Kargl, R.4
Hartter, W.5
Woloszczuk, W.6
Davies, J.7
-
13
-
-
0029022194
-
Thrombomodulin release in baboon sepsis: Its dependence on the dose of Escherichia coli and the presence of tumor necrosis factor
-
Redl, H , G. Schlag, A. Schiesser, and J. Davies 1995. Thrombomodulin release in baboon sepsis: its dependence on the dose of Escherichia coli and the presence of tumor necrosis factor. J. Infect. Dis. 171 1522
-
(1995)
J. Infect. Dis.
, vol.171
, pp. 1522
-
-
Redl, H.1
Schlag, G.2
Schiesser, A.3
Davies, J.4
-
14
-
-
0023491364
-
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
-
Tracey, K., Y Fong, D G. Hesse, K. R. Manogue, A. T. Lee, G. C. Kuo, S. F. Lowry, and A. Cerami. 1987. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia Nature 330.662.
-
(1987)
Nature
, vol.330
, pp. 662
-
-
Tracey, K.1
Fong, Y.2
Hesse, D.G.3
Manogue, K.R.4
Lee, A.T.5
Kuo, G.C.6
Lowry, S.F.7
Cerami, A.8
-
15
-
-
0025193590
-
Survival of primates in LD100 septic shock following therapy with antibody to tumor necrosis factor
-
Hinshaw, I. B., P. Tekamp-Olsen, A. C. Ghana, P A. Lee, F. B. Taylor, C. K Murray, G T. Peer, T E Emerson, R B. Passey, and G. C. Kuo. 1990. Survival of primates in LD100 septic shock following therapy with antibody to tumor necrosis factor Circ Shock 30:279
-
(1990)
Circ Shock
, vol.30
, pp. 279
-
-
Hinshaw, I.B.1
Tekamp-Olsen, P.2
Ghana, A.C.3
Lee, P.A.4
Taylor, F.B.5
Murray, C.K.6
Peer, G.T.7
Emerson, T.E.8
Passey, R.B.9
Kuo, G.C.10
-
16
-
-
0025943512
-
Recombinant soluble TNF receptor proteins protect mice from LPS-induced lethality
-
Lesslauer, W., H. Tabuchi, R Gentz, M Brockhaus, E. J. Schlaeger, G Grau, P F. Piguet, P. Pointaire, P Vassalli, and H R Loetscher. 1991. Recombinant soluble TNF receptor proteins protect mice from LPS-induced lethality Eur J. Immunol 21.2883.
-
(1991)
Eur J. Immunol
, vol.21
, pp. 2883
-
-
Lesslauer, W.1
Tabuchi, H.2
Gentz, R.3
Brockhaus, M.4
Schlaeger, E.J.5
Grau, G.6
Piguet, P.F.7
Pointaire, P.8
Vassalli, P.9
Loetscher, H.R.10
-
17
-
-
0025721017
-
Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin
-
Ashkenazi, A., S. A. Marsters, D. J. Capon, S. M. Chamow, I. S. Figari, P Pennica, D. V. Goeddel, M. A. Palladino, and D. H. Smith 1991. Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin. Proc Natl Acad Sci. USA 88:10535.
-
(1991)
Proc Natl Acad Sci. USA
, vol.88
, pp. 10535
-
-
Ashkenazi, A.1
Marsters, S.A.2
Capon, D.J.3
Chamow, S.M.4
Figari, I.S.5
Pennica, P.6
Goeddel, D.V.7
Palladino, M.A.8
Smith, D.H.9
-
18
-
-
0025827590
-
A tumor necrosis factor receptor IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity
-
Peppel, K , D. Crawford, and B. Beutler. 1991. A tumor necrosis factor receptor IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity. J. Exp. Med. 174:1483
-
(1991)
J. Exp. Med.
, vol.174
, pp. 1483
-
-
Peppel, K.1
Crawford, D.2
Beutler, B.3
-
19
-
-
0026741275
-
Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor a in vitro and in vivo
-
van Zee, K. J., T. Kohno, E Fischer, C S. Rock, L L. Moldawer, and S F. Lowry. 1992. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor a in vitro and in vivo. Proc. Natl. Acad. Sci USA 89:4845
-
(1992)
Proc. Natl. Acad. Sci USA
, vol.89
, pp. 4845
-
-
Van Zee, K.J.1
Kohno, T.2
Fischer, E.3
Rock, C.S.4
Moldawer, L.L.5
Lowry, S.F.6
-
20
-
-
0027198002
-
Soluble tumor necrosis factor receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF earners and TNF antagonists
-
Mohler, K. M., D S. Torrance, C. A. Smith, R E. Goodwin, K. E. Stremler, V. P. Fung, H. Madani, and M B. Widmer. 1993 Soluble tumor necrosis factor receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF earners and TNF antagonists. J Immunol 151:1548.
-
(1993)
J Immunol
, vol.151
, pp. 1548
-
-
Mohler, K.M.1
Torrance, D.S.2
Smith, C.A.3
Goodwin, R.E.4
Stremler, K.E.5
Fung, V.P.6
Madani, H.7
Widmer, M.B.8
-
21
-
-
0028043394
-
Protective effect of 55 kD but not 75 kD soluble tumor necrosis factor receptor-immunoglobulin G fusion proteins in an animal model of Gramnegative sepsis
-
Evans, T. J , D Moyes, A. Carpenter, R. Martin, H. Loetscher, W. Lesslauer, and J. Cohen. 1994. Protective effect of 55 kD but not 75 kD soluble tumor necrosis factor receptor-immunoglobulin G fusion proteins in an animal model of Gramnegative sepsis. J. Exp. Med. 180:2173.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2173
-
-
Evans, T.J.1
Moyes, D.2
Carpenter, A.3
Martin, R.4
Loetscher, H.5
Lesslauer, W.6
Cohen, J.7
-
22
-
-
0023899562
-
A human inhibitor of tumor necrosis factor
-
Seckinger, P., S Isaaz, and J. M. Dayer. 1988 A human inhibitor of tumor necrosis factor. J. Exp. Med. 167:1511.
-
(1988)
J. Exp. Med.
, vol.167
, pp. 1511
-
-
Seckinger, P.1
Isaaz, S.2
Dayer, J.M.3
-
23
-
-
0024307648
-
A tumor necrosis factor binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity
-
Engelmann, H., D. Aderka, M. Rubinstein, D Rotman, and D Wallach. 1989. A tumor necrosis factor binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity. J. Biol. Chem 264:21974.
-
(1989)
J. Biol. Chem
, vol.264
, pp. 21974
-
-
Engelmann, H.1
Aderka, D.2
Rubinstein, M.3
Rotman, D.4
Wallach, D.5
-
24
-
-
0025054391
-
Characterization in vitro of a human tumor necrosis factor binding protein: A soluble form of the tumor necrosis factor receptor
-
Lantz, M., U Gullberg, E. Nillson, and I Olsson 1990. Characterization in vitro of a human tumor necrosis factor binding protein: a soluble form of the tumor necrosis factor receptor. J. Clin. Invest 86:1396.
-
(1990)
J. Clin. Invest
, vol.86
, pp. 1396
-
-
Lantz, M.1
Gullberg, U.2
Nillson, E.3
Olsson, I.4
-
25
-
-
0026708465
-
Imbalance between tumor necrosis factor and soluble TNF receptor concentrations in severe meningococcemia
-
Girardin, E., P. Roux-Lombard, and G. E. Grau. 1992. Imbalance between tumor necrosis factor and soluble TNF receptor concentrations in severe meningococcemia. Immunol. 76:20.
-
(1992)
Immunol.
, vol.76
, pp. 20
-
-
Girardin, E.1
Roux-Lombard, P.2
Grau, G.E.3
-
26
-
-
0026708864
-
High levels of circulating soluble receptors for tumor necrosis factor in chronic B-lymphocytic leucemia and hairy cell leucemia
-
Digel, W., F Porzsolt, M Schmid, F. Hermann, W. Lesslauer, and M Brockhaus. 1992 High levels of circulating soluble receptors for tumor necrosis factor in chronic B-lymphocytic leucemia and hairy cell leucemia. J. Clin. Invest. 89:1690.
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 1690
-
-
Digel, W.1
Porzsolt, F.2
Schmid, M.3
Hermann, F.4
Lesslauer, W.5
Brockhaus, M.6
-
27
-
-
0026516744
-
Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
-
Aderka, D., H Engelmann, Y Maor, C. Brakebusch, and D. Wallach 1992. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J. Exp. Med. 175:323.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 323
-
-
Aderka, D.1
Engelmann, H.2
Maor, Y.3
Brakebusch, C.4
Wallach, D.5
-
28
-
-
0027211704
-
Crystal structure of the soluble human 55-kd TNF receptor-human TNF-β complex: Implications for TNF receptor activation
-
Banner, D., A D'Arcy, W. Janes, R. Gentz, H. J. Schoenfeld, C. Broger, H. Loetscher, and W. Lesslauer. 1993 Crystal structure of the soluble human 55-kd TNF receptor-human TNF-β complex: implications for TNF receptor activation. Cell 73:431
-
(1993)
Cell
, vol.73
, pp. 431
-
-
Banner, D.1
D'Arcy, A.2
Janes, W.3
Gentz, R.4
Schoenfeld, H.J.5
Broger, C.6
Loetscher, H.7
Lesslauer, W.8
-
29
-
-
0011997780
-
Efficacy of a chimeric TNFR-IgG fusion protein to inhibit TNF activity in animal models of septic shock
-
J. Levin. C. R Alving, R. S. Munford, and P. L. Stutz, eds. Excerpta Medica, Amsterdam
-
Loetscher, H R , P Angehrn, E. J. Schlaeger, R. Gentz, and W. Lesslauer. 1993. Efficacy of a chimeric TNFR-IgG fusion protein to inhibit TNF activity in animal models of septic shock. In Bacterial Endotoxin: Recognition and Effector Mechanisms, Endotoxin Research Series, Vol. 2. J. Levin. C. R Alving, R. S. Munford, and P. L. Stutz, eds. Excerpta Medica, Amsterdam, pp. 455-462.
-
(1993)
Bacterial Endotoxin: Recognition and Effector Mechanisms, Endotoxin Research Series
, vol.2
, pp. 455-462
-
-
Loetscher, H.R.1
Angehrn, P.2
Schlaeger, E.J.3
Gentz, R.4
Lesslauer, W.5
-
30
-
-
0028957549
-
Efficacy and safety of monoclonal antibody to human tumor necrosis factor a in patients with sepsis syndrome
-
Abraham, E , R Wunderitik, H Silverman, T. M. Perl, S. Nasraway, H. Levy, R. Bone, R P Wenzel, R. Balk, R Allred, J. E. Pennington, J C Wherry, and T.-A. S. S. Group. 1995 Efficacy and safety of monoclonal antibody to human tumor necrosis factor a in patients with sepsis syndrome. JAMA 273:934.
-
(1995)
JAMA
, vol.273
, pp. 934
-
-
Abraham, E.1
Wunderitik, R.2
Silverman, H.3
Perl, T.M.4
Nasraway, S.5
Levy, H.6
Bone, R.7
Wenzel, R.P.8
Balk, R.9
Allred, R.10
Pennington, J.E.11
Wherry, J.C.12
-
31
-
-
0025298845
-
Monoclonal antibody to TNF in severe septic shock
-
Exley, A R., J Cohen, W. Buurman, R. Owen, J. Lumley, M. Bodmer, S. Stephens, G. Hanson, J. M. Aulakh, A. Riddell, and M. Perry 1990. Monoclonal antibody to TNF in severe septic shock. Lancet 335-1275.
-
(1990)
Lancet
, vol.335
, pp. 1275
-
-
Exley, A.R.1
Cohen, J.2
Buurman, W.3
Owen, R.4
Lumley, J.5
Bodmer, M.6
Stephens, S.7
Hanson, G.8
Aulakh, J.M.9
Riddell, A.10
Perry, M.11
-
32
-
-
0027406403
-
Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis
-
Fisher, C. J., Jr., S M Opal, J F. Dhainaut, S Stephens, J. L. Zimmerman, P. Nightingale, S. J. Harris, R M. H. Schein, E. A Panacek, J. L. Vincent, G E. Fouike, E L Warren, C. Garrard, G Park, M. W Bodmer, J Cohen, C. van der Linden, A. S. Cross, J. C. Sadoff, and T. C. S. S S. group. 1993. Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis. Crit. Care Med 21.318.
-
(1993)
Crit. Care Med
, vol.21
, pp. 318
-
-
Fisher Jr., C.J.1
Opal, S.M.2
Dhainaut, J.F.3
Stephens, S.4
Zimmerman, J.L.5
Nightingale, P.6
Harris, S.J.7
Schein, R.M.H.8
Panacek, E.A.9
Vincent, J.L.10
Fouike, G.E.11
Warren, E.L.12
Garrard, C.13
Park, G.14
Bodmer, M.W.15
Cohen, J.16
Van Der Linden, C.17
Cross, A.S.18
Sadoff, J.C.19
-
33
-
-
0028239555
-
Recombinant human interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome
-
Fisher, C. J., Jr., , J. F. A. Dhainaut, S M. Opal, J. P. Pribble, R. A. Balk, G J Slotman, T. J. Iberti, E. C Rackow, M. J Shapiro, R. L. Greenman, H. D Reines, M P Shelly, B. W. Thompson, J. F. LaBrecque, M. A. Catalane, W. A Knaus, J. C. Sadoff, and P. I. R.-R. S S. S. Group. 1994 Recombinant human interleukin-1 receptor antagonist in the treatment of patients with sepsis syndrome JAMA 271-1836
-
(1994)
JAMA
, vol.271
, pp. 1836
-
-
Fisher Jr., C.J.1
Dhainaut, J.F.A.2
Opal, S.M.3
Pribble, J.P.4
Balk, R.A.5
Slotman, G.J.6
Iberti, T.J.7
Rackow, E.C.8
Shapiro, M.J.9
Greenman, R.L.10
Reines, H.D.11
Shelly, M.P.12
Thompson, B.W.13
LaBrecque, J.F.14
Catalane, M.A.15
Knaus, W.A.16
Sadoff, J.C.17
-
34
-
-
0028018567
-
Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: A randomized, open label, placebo-controlled multicenter trial, the IL-1RA sepsis syndrome study group
-
Fisher, Jr., C. J., G. J. Slotman, S. M. Opal, J. P Pribble, R. C Bone, G. Emmanuel, D. Ng, D C. Bloedow, and M. A. Catalano. 1994. Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open label, placebo-controlled multicenter trial, the IL-1RA sepsis syndrome study group. Crit. Care Med. 22:12
-
(1994)
Crit. Care Med.
, vol.22
, pp. 12
-
-
Fisher Jr., C.J.1
Slotman, G.J.2
Opal, S.M.3
Pribble, J.P.4
Bone, R.C.5
Emmanuel, G.6
Ng, D.7
Bloedow, D.C.8
Catalano, M.A.9
-
35
-
-
0028618426
-
Role of interleukin-1 and the therapeutic potential of interleukin-1 receptor antagonist in sepsis
-
Fisher, Jr , C. J., S M. Opal, S. F. Lowry, J. C. Sadoff, J F LaBrecquc, H C. Donovan, J. L. Lookabough, J. Lemke, J. P. Pribble, S C. Stromatt, G P Vigers, D. A. Russell, and R. C. Thompson. 1994. Role of interleukin-1 and the therapeutic potential of interleukin-1 receptor antagonist in sepsis Circ. Shock 44:1.
-
(1994)
Circ. Shock
, vol.44
, pp. 1
-
-
Fisher Jr., C.J.1
Opal, S.M.2
Lowry, S.F.3
Sadoff, J.C.4
LaBrecquc, J.F.5
Donovan, H.C.6
Lookabough, J.L.7
Lemke, J.8
Pribble, J.P.9
Stromatt, S.C.10
Vigers, G.P.11
Russell, D.A.12
Thompson, R.C.13
-
36
-
-
0028796052
-
New strategies for combatting sepsis: The magic bullet missed the mark, but the search continues
-
Quezado, Z. M., S. M. Banks, and C. Natanson. 1995. New strategies for combatting sepsis: the magic bullet missed the mark, but the search continues Trends Biotechnol 13.56.
-
(1995)
Trends Biotechnol
, vol.13
, pp. 56
-
-
Quezado, Z.M.1
Banks, S.M.2
Natanson, C.3
-
37
-
-
85030288532
-
Ro 45-2081 (TNFR55-IgG1) in the treatment of patients with severe sepsis, and septic shock: Preliminary results
-
Deauville, France
-
Abraham, E., M. Glauser, D. Gelmont, K. Kudsk, D. Lew, J. Carlet, and Leighton. 1995. Ro 45-2081 (TNFR55-IgG1) in the treatment of patients with severe sepsis, and septic shock: preliminary results. In Sec. Intern. Autumnal Them. Meeting on Sepsis Deauville, France
-
(1995)
Sec. Intern. Autumnal Them. Meeting on Sepsis
-
-
Abraham, E.1
Glauser, M.2
Gelmont, D.3
Kudsk, K.4
Lew, D.5
Carlet, J.6
Leighton7
-
38
-
-
0345036008
-
Recombinant 55-kDa TNF receptor stoichiornetry of binding to TNF-alpha and TNF-beta and inhibition of TNF activity
-
Loetscher, H R , R. Gentz, M. Zulauf, A. Lustig, H Tabuchi, E. J. Schlaeger, M. Brockhaus, H. Gallati, M. Manneberg, and W. Lesslauer 1991 Recombinant 55-kDa TNF receptor stoichiornetry of binding to TNF-alpha and TNF-beta and inhibition of TNF activity. J Biol. Chem 266:18324.
-
(1991)
J Biol. Chem
, vol.266
, pp. 18324
-
-
Loetscher, H.R.1
Gentz, R.2
Zulauf, M.3
Lustig, A.4
Tabuchi, H.5
Schlaeger, E.J.6
Brockhaus, M.7
Gallati, H.8
Manneberg, M.9
Lesslauer, W.10
-
39
-
-
0026772736
-
Interleukin 1 receptor blockade improves survival and hemodynamic performance in Escherichia call septic shock, but fails to alter host responses to sublethal endotoxemia
-
Fischer, E., M. A. Marano, K. J. van Zee, C. S. Rock, A. S. Hawes, W. A Thompson, L. deForge, J. S. Kenney, D. G Remick, D. C Bloedow, R C. Thompson, S. F. Lowry, and L. L. Moldawer. 1992. Interleukin 1 receptor blockade improves survival and hemodynamic performance in Escherichia call septic shock, but fails to alter host responses to sublethal endotoxemia J. Clin Invest. 89:1551.
-
(1992)
J. Clin Invest.
, vol.89
, pp. 1551
-
-
Fischer, E.1
Marano, M.A.2
Van Zee, K.J.3
Rock, C.S.4
Hawes, A.S.5
Thompson, W.A.6
DeForge, L.7
Kenney, J.S.8
Remick, D.G.9
Bloedow, D.C.10
Thompson, R.C.11
Lowry, S.F.12
Moldawer, L.L.13
-
40
-
-
0024822793
-
Antibody to cachectin/tumor necrosis factor attenuates interleukin-1 beta and interleukin-6 appearance during overwhelming bacteremia
-
Fong, Y., K J. Tracey, L. L. Moldawer, D. G Hesse, K R. Manogue, J. Kenney. A. T. Lee, G. C. Kuo, A. Allison, S. F. Lowry, and A. Cerami 1989 Antibody to cachectin/tumor necrosis factor attenuates interleukin-1 beta and interleukin-6 appearance during overwhelming bacteremia J Exp Med. 170:1627
-
(1989)
J Exp Med.
, vol.170
, pp. 1627
-
-
Fong, Y.1
Tracey, K.J.2
Moldawer, L.L.3
Hesse, D.G.4
Manogue, K.R.5
Kenney, J.6
Lee, A.T.7
Kuo, G.C.8
Allison, A.9
Lowry, S.F.10
Cerami, A.11
-
41
-
-
0025519183
-
Infusion of tumor necrosis factor causes an increase in circulating TNF binding proteins in humans
-
Lantz, M., S. Malik, I. Slevin, and I. Olsson. 1990. Infusion of tumor necrosis factor causes an increase in circulating TNF binding proteins in humans Cytokine 2.403.
-
(1990)
Cytokine
, vol.2
, pp. 403
-
-
Lantz, M.1
Malik, S.2
Slevin, I.3
Olsson, I.4
-
42
-
-
0028203560
-
A human TNF-α mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon
-
van Zee, K. J , S. A Stackpole, W J. Montegut, M. A Rogy, S. E. Calvano, K. C Hsu. M Chao, C. M. Meschter, H. R. Loetscher, D. Stueber, U Ettlin, B Wipf. W, Lesslauer, S. F Lowry, and L. L. Moldawer. 1994 A human TNF-α mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon J. Exp. Med. 179:1185.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1185
-
-
Van Zee, K.J.1
Stackpole, S.A.2
Montegut, W.J.3
Rogy, M.A.4
Calvano, S.E.5
Hsu, K.C.6
Chao, M.7
Meschter, C.M.8
Loetscher, H.R.9
Stueber, D.10
Ettlin, U.11
Wipf, B.12
Lesslauer, W.13
Lowry, S.F.14
Moldawer, L.L.15
-
43
-
-
0025303041
-
Activation of coagulation after administration of tumor necrosis factor to normal subjects
-
van der Poll, T , T. Buller, H. R ten Cate, C. H. Wortel, K. A. Bauer, S J H van Deventer, C. E. Hack, H P Sauerwem, R. D Rosenburg, and J. W ten Cate 1990. Activation of coagulation after administration of tumor necrosis factor to normal subjects. N. Engl. J. Med. 322:1622.
-
(1990)
N. Engl. J. Med.
, vol.322
, pp. 1622
-
-
Van Der Poll, T.1
Buller, T.2
Ten Cate, H.R.3
Wortel, C.H.4
Bauer, K.A.5
Van Deventer, S.J.H.6
Hack, C.E.7
Sauerwem, H.P.8
Rosenburg, R.D.9
Ten Cate, J.W.10
-
44
-
-
0025258906
-
Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis
-
Echtenacher, B , W. Falk, D. N. Mannel, and P. H. Krammer 1990 Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis. J. Immunol. 145-3762
-
(1990)
J. Immunol.
, vol.145
, pp. 3762
-
-
Echtenacher, B.1
Falk, W.2
Mannel, D.N.3
Krammer, P.H.4
-
45
-
-
0026079224
-
Divergent efficacy of antibody to tumor necrosis factor-alpha in intravascular and peritonitis models of sepsis
-
Bagby, G. J., K. J. Plessala, L A. Wilson, J. J Thompson, and S Nelson 1991 Divergent efficacy of antibody to tumor necrosis factor-alpha in intravascular and peritonitis models of sepsis J. Infect Dis. 163:83.
-
(1991)
J. Infect Dis.
, vol.163
, pp. 83
-
-
Bagby, G.J.1
Plessala, K.J.2
Wilson, L.A.3
Thompson, J.J.4
Nelson, S.5
|