메뉴 건너뛰기




Volumn 20, Issue 5, 1999, Pages 935-941

Adenovirus-mediated expression of interleukin-12 induces natural killer cell activity and complements adenovirus-directed gp75 treatment of melanoma lung metastases

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRIDAE; MURINAE;

EID: 0033128827     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.20.5.3412     Document Type: Article
Times cited : (15)

References (66)
  • 1
    • 0029584391 scopus 로고
    • Role of interleukin-12 (IL-12) as an anti-tumor agent: Experimental biology and clinical application
    • Zitvogel, L., and M. T. Lotze. 1995. Role of interleukin-12 (IL-12) as an anti-tumor agent: experimental biology and clinical application. Res. Immunol. 146:628-638.
    • (1995) Res. Immunol. , vol.146 , pp. 628-638
    • Zitvogel, L.1    Lotze, M.T.2
  • 3
    • 0027494385 scopus 로고
    • Action of natural killer cells and macrophages in cancer
    • Klein, E., and A. Mantovani. 1993. Action of natural killer cells and macrophages in cancer. Curr. Opin. Immunol. 5:714-718.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 714-718
    • Klein, E.1    Mantovani, A.2
  • 4
    • 0029834981 scopus 로고    scopus 로고
    • Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles
    • D'Andrea, A., C. Chang, J. J. Phillips, and L. L. Lanier. 1996. Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles. J. Exp. Med. 184:789-794.
    • (1996) J. Exp. Med. , vol.184 , pp. 789-794
    • D'Andrea, A.1    Chang, C.2    Phillips, J.J.3    Lanier, L.L.4
  • 6
    • 0028265155 scopus 로고
    • Interleukin 12 induces stable priming for interferon γ (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production is established Th2 cell clones
    • Manetti, R., F. Gerosa, M. G. Giudizi, R. Biagiotti, P. Parronchi, M. P. Piccinni, S. Sampognaro, E. Maggi, S. Romagnani, and G. Trinchieri. 1994. Interleukin 12 induces stable priming for interferon γ (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production is established Th2 cell clones. J. Exp. Med. 179:1273-1283.
    • (1994) J. Exp. Med. , vol.179 , pp. 1273-1283
    • Manetti, R.1    Gerosa, F.2    Giudizi, M.G.3    Biagiotti, R.4    Parronchi, P.5    Piccinni, M.P.6    Sampognaro, S.7    Maggi, E.8    Romagnani, S.9    Trinchieri, G.10
  • 7
    • 0029614848 scopus 로고
    • The role of macrophage- and dendritic cell-derived IL-12 in Th1 phenotype development
    • O'Garra, A., N. Hosken, S. Macatonia, C. A. Wenner, and K. Murphy. 1995. The role of macrophage- and dendritic cell-derived IL-12 in Th1 phenotype development. Res. Immunol. 146:466-472.
    • (1995) Res. Immunol. , vol.146 , pp. 466-472
    • O'Garra, A.1    Hosken, N.2    Macatonia, S.3    Wenner, C.A.4    Murphy, K.5
  • 8
    • 0029557309 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions
    • Trinchieri, G., and P. Scott. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions. Res. Immunol. 146:423-431.
    • (1995) Res. Immunol. , vol.146 , pp. 423-431
    • Trinchieri, G.1    Scott, P.2
  • 9
    • 0029584427 scopus 로고
    • A sequence of cellular and molecular events involved in IL12-induccd tumor regression
    • Fujiwara, H., J. P. Zou, S. Herrmann, and T. Hamaoka. 1995. A sequence of cellular and molecular events involved in IL12-induccd tumor regression. Res. Immunol. 146:638-644.
    • (1995) Res. Immunol. , vol.146 , pp. 638-644
    • Fujiwara, H.1    Zou, J.P.2    Herrmann, S.3    Hamaoka, T.4
  • 10
    • 0027415223 scopus 로고
    • Effects of interferons and cytokines on melanoma cells. J
    • Garbe, C., and K. Krasagakis. 1993. Effects of interferons and cytokines on melanoma cells. J. Invest. Dermatol. 100:239S-244S.
    • (1993) Invest. Dermatol. , vol.100
    • Garbe, C.1    Krasagakis, K.2
  • 11
    • 0003840121 scopus 로고
    • Interferon γ induces lung colonization by intravenously inoculated B16 melanoma cells in parallel with enhanced expression of class I major histocompatibility complex antigens
    • Taniguchi, K., M. Petersson, P. Hoglund, R. Kiessling, G. Klein, and K. Karre. 1987. Interferon γ induces lung colonization by intravenously inoculated B16 melanoma cells in parallel with enhanced expression of class I major histocompatibility complex antigens. Proc. Natl. Acad. Sci. USA 84: 3405-3409.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3405-3409
    • Taniguchi, K.1    Petersson, M.2    Hoglund, P.3    Kiessling, R.4    Klein, G.5    Karre, K.6
  • 13
    • 0030057511 scopus 로고    scopus 로고
    • Construction of a double recombinant adenovirus vector expressing a heterodimeric cytokine: In vitro and in vivo production of biologically active interleukin-12
    • Bramson, J., M. Hitt, W. S. Gallichan, K. L. Rosenthal, J. Gauldie, and F. L. Graham. 1996. Construction of a double recombinant adenovirus vector expressing a heterodimeric cytokine: in vitro and in vivo production of biologically active interleukin-12. Hum. Gene Ther. 7:333-342.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 333-342
    • Bramson, J.1    Hitt, M.2    Gallichan, W.S.3    Rosenthal, K.L.4    Gauldie, J.5    Graham, F.L.6
  • 14
    • 0028902754 scopus 로고
    • Modulation of gene expression after replication-deficient, recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector
    • Hersh, J., R. G. Crystal, and B. Bewig. 1995. Modulation of gene expression after replication-deficient, recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector. Gene Ther. 2:124-131.
    • (1995) Gene Ther. , vol.2 , pp. 124-131
    • Hersh, J.1    Crystal, R.G.2    Bewig, B.3
  • 15
    • 0028795075 scopus 로고
    • In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine
    • Hirschowitz, E. A., A. Ohwada, W. R. Pascal, T. J. Russi, and R. G. Crystal. 1995. In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine. Hum. Gene Ther. 6:1055-1063.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 1055-1063
    • Hirschowitz, E.A.1    Ohwada, A.2    Pascal, W.R.3    Russi, T.J.4    Crystal, R.G.5
  • 17
    • 0028786994 scopus 로고
    • Implicating a role for immune recognition of self in tumor rejection: Passive immunization against the brown locus protein
    • Hara, I., Y. Takechi, and A. N. Houghton. 1995. Implicating a role for immune recognition of self in tumor rejection: Passive immunization against the brown locus protein. J. Exp. Med. 182:1609-1614.
    • (1995) J. Exp. Med. , vol.182 , pp. 1609-1614
    • Hara, I.1    Takechi, Y.2    Houghton, A.N.3
  • 19
    • 0023763999 scopus 로고
    • IFN-treatment of B16-F1 versus B16-F10: Relative impact on non-adaptive and T-cell-mediated immune defense in metastatic spread
    • Zoller, M. 1988. IFN-treatment of B16-F1 versus B16-F10: relative impact on non-adaptive and T-cell-mediated immune defense in metastatic spread. Clin. Exp. Metastasis 6:411-429.
    • (1988) Clin. Exp. Metastasis , vol.6 , pp. 411-429
    • Zoller, M.1
  • 20
    • 0025296701 scopus 로고
    • Differentiation and the tumorigenetic and metastatic phenotype of murine melanoma cells
    • Kameyama, K., W. D. Vieira, K. Tsukamoto, L. W. Law, and V. J. Hearing. 1990. Differentiation and the tumorigenetic and metastatic phenotype of murine melanoma cells. Int. J. Cancer 45:1151-1158.
    • (1990) Int. J. Cancer , vol.45 , pp. 1151-1158
    • Kameyama, K.1    Vieira, W.D.2    Tsukamoto, K.3    Law, L.W.4    Hearing, V.J.5
  • 21
    • 0025906766 scopus 로고
    • The effect of tramfected MHC class I genes on sensitivity to natural killer cells
    • Holseher, M., A. L. Givan, and C. G. Brooks. 1991. The effect of tramfected MHC class I genes on sensitivity to natural killer cells. Immunology 73:44-51.
    • (1991) Immunology , vol.73 , pp. 44-51
    • Holseher, M.1    Givan, A.L.2    Brooks, C.G.3
  • 22
    • 0018864610 scopus 로고
    • The pathogenesis of cancer metastasis
    • Poste, G., and I. J. Fidler. 1980. The pathogenesis of cancer metastasis. Nature 283:139-146.
    • (1980) Nature , vol.283 , pp. 139-146
    • Poste, G.1    Fidler, I.J.2
  • 23
    • 0019410977 scopus 로고
    • Definitive evidence that natural killer (NK) cells inhibit experimental tumor metastases in vivo
    • Hanna, N., and R. C. Burton. 1981. Definitive evidence that natural killer (NK) cells inhibit experimental tumor metastases in vivo. J. Immunol. 127: 1754-1758.
    • (1981) J. Immunol. , vol.127 , pp. 1754-1758
    • Hanna, N.1    Burton, R.C.2
  • 24
    • 0023738916 scopus 로고
    • A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity
    • Decker, T., and M. L. Lohmann-Matthes. 1988 A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity. J. Immunol. Methods 115:61-69.
    • (1988) J. Immunol. Methods , vol.115 , pp. 61-69
    • Decker, T.1    Lohmann-Matthes, M.L.2
  • 25
    • 0030770344 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors
    • Song, W., H. L. Kong, P. Traktman, and R. G. Crystal. 1997. Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors. Hum. Gene Ther. 8:1207-1217.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 1207-1217
    • Song, W.1    Kong, H.L.2    Traktman, P.3    Crystal, R.G.4
  • 26
    • 0025317338 scopus 로고
    • The melanoma antigen gp75 is the human homologue of the mouse b (Brown) locus gene product
    • Vijayasaradhi, S., B. Bouchard, and A. N. Houghton. 1990. The melanoma antigen gp75 is the human homologue of the mouse b (Brown) locus gene product. J. Exp. Med. 171:1375-1380.
    • (1990) J. Exp. Med. , vol.171 , pp. 1375-1380
    • Vijayasaradhi, S.1    Bouchard, B.2    Houghton, A.N.3
  • 27
    • 0026051621 scopus 로고
    • Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (Brown) locus product
    • Vijayasaradhi, S., P. M. Doskoch, and A. N. Houghton. 1991. Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (Brown) locus product. Exp. Cell Res. 196:233-240.
    • (1991) Exp. Cell Res. , vol.196 , pp. 233-240
    • Vijayasaradhi, S.1    Doskoch, P.M.2    Houghton, A.N.3
  • 28
    • 0026081071 scopus 로고
    • Purification of an autoantigenic 75-kDa human melanosomal glycoprotein
    • Vijayasaradhi, S., and A. N. Houghton. 1991. Purification of an autoantigenic 75-kDa human melanosomal glycoprotein. Int. J. Cancer 47:298-303.
    • (1991) Int. J. Cancer , vol.47 , pp. 298-303
    • Vijayasaradhi, S.1    Houghton, A.N.2
  • 29
    • 0028906594 scopus 로고
    • Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes
    • Wang, R. F., P. F. Rohbins, Y. Kawakami, X. Q. Kang, and S. A. Rosenberg. 1995. Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes. J. Exp. Med. 181:799-804.
    • (1995) J. Exp. Med. , vol.181 , pp. 799-804
    • Wang, R.F.1    Rohbins, P.F.2    Kawakami, Y.3    Kang, X.Q.4    Rosenberg, S.A.5
  • 30
    • 0029912726 scopus 로고    scopus 로고
    • Immune response to a differentiation antigen induced by altered antigen: A study of tumor rejection and autoimmunity
    • Naftzger, C., Y. Takechi, H. Kohda, I. Hara, S. Vijayasaradhi, and A. N. Houghton. 1996. Immune response to a differentiation antigen induced by altered antigen: a study of tumor rejection and autoimmunity. Proc. Natl. Acad. Sci. USA 93:14809-14814.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14809-14814
    • Naftzger, C.1    Takechi, Y.2    Kohda, H.3    Hara, I.4    Vijayasaradhi, S.5    Houghton, A.N.6
  • 31
    • 0029560716 scopus 로고
    • Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector
    • Juillard, V., P. Villefroy, D. Godfrin, A. Pavirani, A. Venet, and J. G. Guillet. 1995. Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector. Eur. J. Immunol. 25:3467-3473.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3467-3473
    • Juillard, V.1    Villefroy, P.2    Godfrin, D.3    Pavirani, A.4    Venet, A.5    Guillet, J.G.6
  • 32
    • 0029145960 scopus 로고
    • Intratracheal gene delivery with adenoviral vector induces elevated systemic IgG and mucosal IgA antibodies to adenovirus and β-galactosidase
    • Van Ginkel, F. W., C. Liu, J. W. Simecka, J. Y. Dong, T. Greenway, R. A. Frizzell, H. Kiyono, J. R. McGhee, and D. W. Pascual. 1995. Intratracheal gene delivery with adenoviral vector induces elevated systemic IgG and mucosal IgA antibodies to adenovirus and β-galactosidase. Hum. Gene Ther. 6:895-903.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 895-903
    • Van Ginkel, F.W.1    Liu, C.2    Simecka, J.W.3    Dong, J.Y.4    Greenway, T.5    Frizzell, R.A.6    Kiyono, H.7    McGhee, J.R.8    Pascual, D.W.9
  • 33
    • 0030047315 scopus 로고    scopus 로고
    • Therapeutic antiturnor response after immunization with a recombinant adenovirus encoding a model tumor-associated antigen
    • Chen, P. W., M. Wang, V. Bronte, Y. Zhai, S. A. Rosenberg, and N. P. Restifo. 1996. Therapeutic antiturnor response after immunization with a recombinant adenovirus encoding a model tumor-associated antigen. J. Immunol. 156:224-231.
    • (1996) J. Immunol. , vol.156 , pp. 224-231
    • Chen, P.W.1    Wang, M.2    Bronte, V.3    Zhai, Y.4    Rosenberg, S.A.5    Restifo, N.P.6
  • 34
    • 0029936764 scopus 로고    scopus 로고
    • Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
    • Tripathy, S. K., H. B. Black, E. Goldwasser, and J. M. Leiden. 1996. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat. Med. 2:545-550.
    • (1996) Nat. Med. , vol.2 , pp. 545-550
    • Tripathy, S.K.1    Black, H.B.2    Goldwasser, E.3    Leiden, J.M.4
  • 35
    • 9244220682 scopus 로고    scopus 로고
    • Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo
    • Yang, Y., K. U. Jooss, Q. Su, H. C. Ertl, and J. M. Wilson. 1996. Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo. Gene Ther. 3:137-144.
    • (1996) Gene Ther. , vol.3 , pp. 137-144
    • Yang, Y.1    Jooss, K.U.2    Su, Q.3    Ertl, H.C.4    Wilson, J.M.5
  • 36
    • 0030026871 scopus 로고    scopus 로고
    • Antigen-specific tumor vaccines: Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy
    • Zhai, Y., J. C. Yang, Y. Kawakami, P. Spiess, S. C. Wadsworth, L. M. Cardoza, L. A. Couture, A. E. Smith, and S. A. Rosenberg. 1996. Antigen-specific tumor vaccines: development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy. J. Immunol. 156:700-710.
    • (1996) J. Immunol. , vol.156 , pp. 700-710
    • Zhai, Y.1    Yang, J.C.2    Kawakami, Y.3    Spiess, P.4    Wadsworth, S.C.5    Cardoza, L.M.6    Couture, L.A.7    Smith, A.E.8    Rosenberg, S.A.9
  • 38
    • 0025021404 scopus 로고
    • Cytokine-mediated modulation of HLA-Class II, ICAM-1, LFA-3 and tumor-associated antigen profile of melanoma cells. Comparison with anti-proliferative activity by rIL1-β, rTNF-α, rIFN-γ, rIL4 and their combinations
    • Mortarini, R., F. Belli, G. Parmiani, and A. Anichini. 1990. Cytokine-mediated modulation of HLA-Class II, ICAM-1, LFA-3 and tumor-associated antigen profile of melanoma cells. Comparison with anti-proliferative activity by rIL1-β, rTNF-α, rIFN-γ, rIL4 and their combinations. Int. J. Cancer 45:334-341.
    • (1990) Int. J. Cancer , vol.45 , pp. 334-341
    • Mortarini, R.1    Belli, F.2    Parmiani, G.3    Anichini, A.4
  • 39
    • 0022532907 scopus 로고
    • Effects of the immunomodulator LS 2616 on growth and metastasis of the murine B16-F10 melanoma
    • Kalland, T. 1986. Effects of the immunomodulator LS 2616 on growth and metastasis of the murine B16-F10 melanoma. Cancer Res. 46:3018-3022.
    • (1986) Cancer Res. , vol.46 , pp. 3018-3022
    • Kalland, T.1
  • 40
    • 0029848051 scopus 로고    scopus 로고
    • Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12
    • Bramson, J. L., M. Hitt, C. L. Addison, W. J. Muller, J. Gauldie, and F. L. Graham. 1996. Direct intratumoral injection of an adenovirus expressing interleukin-12 induces regression and long-lasting immunity that is associated with highly localized expression of interleukin-12. Hum. Gene Ther. 7:1995-2002.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1995-2002
    • Bramson, J.L.1    Hitt, M.2    Addison, C.L.3    Muller, W.J.4    Gauldie, J.5    Graham, F.L.6
  • 42
    • 0031178963 scopus 로고    scopus 로고
    • Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer
    • Chen, L., D. Chen, E. Block, M. O'Donnell, D. W. Kufe, and S. K. Clinton. 1997. Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer. J. Immunol. 159: 351-359.
    • (1997) J. Immunol. , vol.159 , pp. 351-359
    • Chen, L.1    Chen, D.2    Block, E.3    O'Donnell, M.4    Kufe, D.W.5    Clinton, S.K.6
  • 43
    • 0030931602 scopus 로고    scopus 로고
    • Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression
    • Putzer, B. M., M. Hitt, W. J. Muller, P. Emtage, J. Gauldie, and F. L. Graham. 1997. Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. Proc. Natl. Acad. Sci. USA 94:10889-10894.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10889-10894
    • Putzer, B.M.1    Hitt, M.2    Muller, W.J.3    Emtage, P.4    Gauldie, J.5    Graham, F.L.6
  • 44
    • 0032032755 scopus 로고    scopus 로고
    • Construction of vectors expressing bioactive heterodimeric and single-chain murine interleukin-12 for gene therapy
    • Lee, Y. L. M. H. Tao, Y. H. Chow, and B. L. Chiang. 1998. Construction of vectors expressing bioactive heterodimeric and single-chain murine interleukin-12 for gene therapy. Hum. Gene Ther. 9:457-465.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 457-465
    • Lee, Y.L.1    Tao, M.H.2    Chow, Y.H.3    Chiang, B.L.4
  • 45
    • 0026691714 scopus 로고
    • Regulation of human cytolytic lymphocyte responses by interleukin-12
    • Gately, M. K., A. G. Wolitzky, P. M. Quinn, and R. Chizzonite. 1992. Regulation of human cytolytic lymphocyte responses by interleukin-12. Cell Immunol. 143:127-142.
    • (1992) Cell Immunol. , vol.143 , pp. 127-142
    • Gately, M.K.1    Wolitzky, A.G.2    Quinn, P.M.3    Chizzonite, R.4
  • 46
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi, M., L. Fitz, M. Ryan, R. M. Hewick, S. C. Clark, S. Chan, R. Loudon, F. Sherman, B. Perussia, and G. Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170: 827-845.
    • (1989) J. Exp. Med. , vol.170 , pp. 827-845
    • Kobayashi, M.1    Fitz, L.2    Ryan, M.3    Hewick, R.M.4    Clark, S.C.5    Chan, S.6    Loudon, R.7    Sherman, F.8    Perussia, B.9    Trinchieri, G.10
  • 48
    • 0030834180 scopus 로고    scopus 로고
    • Involvement of T-cell subsets and natural killer (NK) cells in the growth suppression of murine fibrosarcoma cells transfected with interleukin-12 (IL-12) genes
    • Schmitt, M., H. Ikeda, Y. Nagata, X. Gu, L. Wang, K Kuribayashi, and H. Shiku. 1997. Involvement of T-cell subsets and natural killer (NK) cells in the growth suppression of murine fibrosarcoma cells transfected with interleukin-12 (IL-12) genes. Int. J. Cancer 72:505-511.
    • (1997) Int. J. Cancer , vol.72 , pp. 505-511
    • Schmitt, M.1    Ikeda, H.2    Nagata, Y.3    Gu, X.4    Wang, L.5    Kuribayashi, K.6    Shiku, H.7
  • 50
    • 0025819340 scopus 로고
    • Induction of interferon-γ production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers
    • Chan, S. H., B. Perussia, J. W. Gupta, M. Kobayashi, M. Pospisil, H. A. Young, S. F. Wolf, D. Young, S. C. Clark, and G. Trinchieri. 1991. Induction of interferon-γ production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J. Exp. Med. 173:869-879.
    • (1991) J. Exp. Med. , vol.173 , pp. 869-879
    • Chan, S.H.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Pospisil, M.5    Young, H.A.6    Wolf, S.F.7    Young, D.8    Clark, S.C.9    Trinchieri, G.10
  • 55
    • 0030739621 scopus 로고    scopus 로고
    • Antitumor efficacy of adenocarcinoma cells engineered to produce interleukin 12 (IL-12) or other cytokincscompared with exogenous IL-12
    • Cavallo, F., P. Signorelli, M. Giovarelli, P. Musiani, A. Modesti, M. J. Brunda, M. P. Colombo, and G. Forni. 1997. Antitumor efficacy of adenocarcinoma cells engineered to produce interleukin 12 (IL-12) or other cytokincscompared with exogenous IL-12. J. Natl. Cancer Inst. 89:1049-1058.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1049-1058
    • Cavallo, F.1    Signorelli, P.2    Giovarelli, M.3    Musiani, P.4    Modesti, A.5    Brunda, M.J.6    Colombo, M.P.7    Forni, G.8
  • 56
    • 0029885750 scopus 로고    scopus 로고
    • IL-12 is an effective adjuvant to recombinant vaccinia virus-based tumor vaccines: Enhancement by simultaneous B7-1 expression
    • Rao, J. B., R. S. Chamberlain, V. Bronte, M. W. Carroll, K. R. Irvine, B. Moss, S. A. Rosenberg, and N. P. Restifo. 1996 IL-12 is an effective adjuvant to recombinant vaccinia virus-based tumor vaccines: enhancement by simultaneous B7-1 expression. J. Immunol. 156:3357-3365.
    • (1996) J. Immunol. , vol.156 , pp. 3357-3365
    • Rao, J.B.1    Chamberlain, R.S.2    Bronte, V.3    Carroll, M.W.4    Irvine, K.R.5    Moss, B.6    Rosenberg, S.A.7    Restifo, N.P.8
  • 57
    • 0030976279 scopus 로고    scopus 로고
    • The effect of interleukin 12 desensitization on the antitumor efficacy of recombinant interleukin 12
    • Coughlin, C. M., M. Wysocka, G. Trinchieri, and W. M. Lee. 1997. The effect of interleukin 12 desensitization on the antitumor efficacy of recombinant interleukin 12. Cancer Res. 57:2460-2467.
    • (1997) Cancer Res. , vol.57 , pp. 2460-2467
    • Coughlin, C.M.1    Wysocka, M.2    Trinchieri, G.3    Lee, W.M.4
  • 58
    • 0029868353 scopus 로고    scopus 로고
    • IL 12: A key cytokine in immune regulation
    • Lamont, A. G., and L. Adorini. 1996. IL 12: a key cytokine in immune regulation. Immunol. Today 17:214-217.
    • (1996) Immunol. Today , vol.17 , pp. 214-217
    • Lamont, A.G.1    Adorini, L.2
  • 60
    • 0028957492 scopus 로고
    • Mechanism of interleukin 12-mediated toxicities during experimental viral infections: Role of tumor necrosis factor and glucocorticoids
    • Orange, J. S., T. P. Salazar-Mather, S. M. Opal, R. L. Spencer, A. H. Miller, B. S. McEwwn, and C. A. Biron. 1995. Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids. J. Exp. Med. 181:901-914.
    • (1995) J. Exp. Med. , vol.181 , pp. 901-914
    • Orange, J.S.1    Salazar-Mather, T.P.2    Opal, S.M.3    Spencer, R.L.4    Miller, A.H.5    McEwwn, B.S.6    Biron, C.A.7
  • 61
    • 0030662705 scopus 로고    scopus 로고
    • Protective effect of a single interleukin-12 (IL-12) predose against the toxicity of subsequent chronic IL-12 in mice: Role of cytokines and glucocorticoids
    • Sacco, S., H. Heremans, B. Echtenacher, W. A. Buurman, Z. Amraoui, M. Goldman, and P. Ghezzi. 1997. Protective effect of a single interleukin-12 (IL-12) predose against the toxicity of subsequent chronic IL-12 in mice: role of cytokines and glucocorticoids. Blood 90:4473-4479.
    • (1997) Blood , vol.90 , pp. 4473-4479
    • Sacco, S.1    Heremans, H.2    Echtenacher, B.3    Buurman, W.A.4    Amraoui, Z.5    Goldman, M.6    Ghezzi, P.7
  • 62
    • 0029823656 scopus 로고    scopus 로고
    • Cytokine production and antitumor effect of a nonreplicating, noncytopathic recombinant vaccinia virus expressing interleukin-12
    • discussion 282-283
    • Meko, J. B., K. Tsung, and J. A. Norton. 1996. Cytokine production and antitumor effect of a nonreplicating, noncytopathic recombinant vaccinia virus expressing interleukin-12. Surgery 120:274-282; discussion 282-283.
    • (1996) Surgery , vol.120 , pp. 274-282
    • Meko, J.B.1    Tsung, K.2    Norton, J.A.3
  • 63
    • 0030589377 scopus 로고    scopus 로고
    • Immunotherapy of experimental metastases by vaccination with interleukin gene-transduced adenocarcinoma cells sharing tumor -associated antigens. Comparison between IL-2 and IL-2 gene-transduced tumor cell vaccines
    • Rodolfo, M., C. Zilocchi, C. Melani, B. Capetti, I. Arioli, G. Parmiani, and M. P. Colombo. 1996. Immunotherapy of experimental metastases by vaccination with interleukin gene-transduced adenocarcinoma cells sharing tumor -associated antigens. Comparison between IL-2 and IL-2 gene-transduced tumor cell vaccines. J. Immunol. 157:5536-5542.
    • (1996) J. Immunol. , vol.157 , pp. 5536-5542
    • Rodolfo, M.1    Zilocchi, C.2    Melani, C.3    Capetti, B.4    Arioli, I.5    Parmiani, G.6    Colombo, M.P.7
  • 64
    • 0031137564 scopus 로고    scopus 로고
    • Immune responsiveness to a murine mammary carcinoma modified to express B7-1, interleukin-12, or GM-CSF
    • Aruga, E., A. Aruga, M. J. Arca, W. M. Lee, N. S. Yang, J. W. Smith, II, and A. F., Chang. 1997. Immune responsiveness to a murine mammary carcinoma modified to express B7-1, interleukin-12, or GM-CSF. Cancer Gene Ther. 4:157-166.
    • (1997) Cancer Gene Ther. , vol.4 , pp. 157-166
    • Aruga, E.1    Aruga, A.2    Arca, M.J.3    Lee, W.M.4    Yang, N.S.5    Smith J.W. II6    Chang, A.F.7
  • 65
    • 0029947820 scopus 로고    scopus 로고
    • Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors
    • Rakhmilevich, A. L., J. Tuner, M. J. Ford, D. McCabe, W. H. Sun, P. M. Sondel, K. Grota, and N. S. Yang. 1996. Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors. Proc. Natl. Acad. Sci. USA 93:6291-4296.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6291-14296
    • Rakhmilevich, A.L.1    Tuner, J.2    Ford, M.J.3    McCabe, D.4    Sun, W.H.5    Sondel, P.M.6    Grota, K.7    Yang, N.S.8
  • 66
    • 0029681849 scopus 로고    scopus 로고
    • Injection of complementary DNA encoding interlcukin-12 inhibits tumor establishment at a distant site in a murine renal carcinoma model
    • Tan, J., C. A. Newton, J. Y. Djeu, D. E. Gutsch, A. E. Chang, N. S. Yang, T. W. Klein, and Y. Hua. 1996. Injection of complementary DNA encoding interlcukin-12 inhibits tumor establishment at a distant site in a murine renal carcinoma model. Cancer Res. 56:3399-3403.
    • (1996) Cancer Res. , vol.56 , pp. 3399-3403
    • Tan, J.1    Newton, C.A.2    Djeu, J.Y.3    Gutsch, D.E.4    Chang, A.E.5    Yang, N.S.6    Klein, T.W.7    Hua, Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.