-
1
-
-
0021887675
-
Department of veterans affairs epilepsy cooperative study no 118 group. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures
-
Mattson, R.H., Cramer, J.A. and Collins, J.F. department of veterans affairs epilepsy cooperative study no 118 group. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. New England Journal of Medicine 1985; 313: 145- 151.
-
(1985)
New England Journal of Medicine
, vol.313
, pp. 145-151
-
-
Mattson, R.H.1
Cramer, J.A.2
Collins, J.F.3
-
2
-
-
0026794763
-
Department of veterans affairs epilepsy cooperative study no 264 group. A comparison of valproate with carbamazepine for the treatment of partial seizures and secondarily generalized tonic-clonic seizures in adults
-
Mattson, R.H., Cramer, J.A. and Collins, J.F. Department of veterans affairs epilepsy cooperative study no 264 group. A comparison of valproate with carbamazepine for the treatment of partial seizures and secondarily generalized tonic-clonic seizures in adults. New England Journal of Medicine 1992; 327: 765-771.
-
(1992)
New England Journal of Medicine
, vol.327
, pp. 765-771
-
-
Mattson, R.H.1
Cramer, J.A.2
Collins, J.F.3
-
3
-
-
0028220347
-
Strategies in antiepileptic drug development: Is rational drug design superiorto random screening and structural variation?
-
Löscher, W. and Schmidt, D. Strategies in antiepileptic drug development: Is rational drug design superiorto random screening and structural variation? Epilepsy Research 1994; 17: 95-134.
-
(1994)
Epilepsy Research
, vol.17
, pp. 95-134
-
-
Löscher, W.1
Schmidt, D.2
-
4
-
-
0002376924
-
Principles of antiepileptic drug action
-
Eds R.H. Levy, R.H. Mattson and B.S. Meldrum. New York, Raven Press
-
th Edition (Eds R.H. Levy, R.H. Mattson and B.S. Meldrum). New York, Raven Press, 1995: pp. 61-77.
-
(1995)
th Edition
, pp. 61-77
-
-
Macdonald, R.L.1
Meldrum, B.S.2
-
5
-
-
0018412873
-
Low cerebrospinal fluid γ -aminobutyric acid content in seizure patients
-
Wood, J.H., Hare, T.A., Glaeser, B.S., Ballenger, J.C. and Post, R.M. Low cerebrospinal fluid γ -aminobutyric acid content in seizure patients. Neurology 1979; 29: 1203-1208.
-
(1979)
Neurology
, vol.29
, pp. 1203-1208
-
-
Wood, J.H.1
Hare, T.A.2
Glaeser, B.S.3
Ballenger, J.C.4
Post, R.M.5
-
6
-
-
0023629517
-
GABA and amino acid concentrations in lumbar CSF in patients with treated and untreated epilepsy
-
Crawford, P.M. and Chadwick, D.W. GABA and amino acid concentrations in lumbar CSF in patients with treated and untreated epilepsy. Epilepsy Research 1987; 1: 328-338.
-
(1987)
Epilepsy Research
, vol.1
, pp. 328-338
-
-
Crawford, P.M.1
Chadwick, D.W.2
-
7
-
-
0030483254
-
Low brain GABA level is associated with poor seizure control
-
Petroff, O.A.C., Rothman, D.L., Behar, K.L. and Mattson, R.H. Low brain GABA level is associated with poor seizure control. Annals of Neurology 1996; 40: 908-911.
-
(1996)
Annals of Neurology
, vol.40
, pp. 908-911
-
-
Petroff, O.A.C.1
Rothman, D.L.2
Behar, K.L.3
Mattson, R.H.4
-
8
-
-
0014532570
-
Effects of di-n-propylacetate, an anticonvulsive compound, on GABA metabolism
-
Godin, Y., Heiner, L., Mark, J. and Mandel, P. Effects of di-n-propylacetate, an anticonvulsive compound, on GABA metabolism. Journal of Neurochemistry 1969; 16: 869-873.
-
(1969)
Journal of Neurochemistry
, vol.16
, pp. 869-873
-
-
Godin, Y.1
Heiner, L.2
Mark, J.3
Mandel, P.4
-
9
-
-
0025274892
-
Neurophysiological and biochemical changes evokedby valprotic acid in the central nervous system
-
Cotariu, D., Zaidman, J.L. and Evans, S. Neurophysiological and biochemical changes evokedby valprotic acid in the central nervous system. Progress in Neurobiology 1990; 34: 343-354.
-
(1990)
Progress in Neurobiology
, vol.34
, pp. 343-354
-
-
Cotariu, D.1
Zaidman, J.L.2
Evans, S.3
-
10
-
-
0027480424
-
Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain
-
Löscher, W Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain. Neurochemistry Research 1993; 18: 485- 502.
-
(1993)
Neurochemistry Research
, vol.18
, pp. 485-502
-
-
Löscher, W.1
-
11
-
-
0000886469
-
Valproic acid mechanisms of action
-
Eds R.H. Levy, R.H. Mattson and B.S. Meldrum. New York, Raven Press
-
th Edition (Eds R.H. Levy, R.H. Mattson and B.S. Meldrum). New York, Raven Press, 1995: pp. 581-588.
-
(1995)
th Edition
, pp. 581-588
-
-
Fariello, R.G.1
Varasi, M.2
Smith, M.C.3
-
12
-
-
0021879046
-
Cerebrospinal fluid γ -aminobutyric acid levels in children with different types of epilepsy: Effect of anticonvulsant treatment
-
Löscher, W and Siemes, H. Cerebrospinal fluid γ -aminobutyric acid levels in children with different types of epilepsy: Effect of anticonvulsant treatment. Epilepsia 1985; 26: 314-319.
-
(1985)
Epilepsia
, vol.26
, pp. 314-319
-
-
Löscher, W.1
Siemes, H.2
-
13
-
-
0024261104
-
Alteration of amino acid content of cerebrospinal fluid from patients with epilepsy
-
Araki, K., Harada, M., Ueda, Y, Takino, T. and Kuryama, K. Alteration of amino acid content of cerebrospinal fluid from patients with epilepsy. Acta Neurologica Scandinavica 1988; 78: 473-479.
-
(1988)
Acta Neurologica Scandinavica
, vol.78
, pp. 473-479
-
-
Araki, K.1
Harada, M.2
Ueda, Y.3
Takino, T.4
Kuryama, K.5
-
14
-
-
0024558283
-
Inhibitory and excitatory amino acids in cerebrospinal fluid of chronic epileptic patients
-
Pitkänen, A., Matilainen, R., Halonen, T., Kutvonen, R., Hartikainen, O. and Riekkinen, P. Inhibitory and excitatory amino acids in cerebrospinal fluid of chronic epileptic patients. Journal of Neurological Transmission 1989; 76: 221-230.
-
(1989)
Journal of Neurological Transmission
, vol.76
, pp. 221-230
-
-
Pitkänen, A.1
Matilainen, R.2
Halonen, T.3
Kutvonen, R.4
Hartikainen, O.5
Riekkinen, P.6
-
15
-
-
0018675782
-
Treatment of Parkinson's disease with sodium valproate: Clinical, pharmacological, and biochemical observations
-
Nutt, J., Williams, A., Plotkin, C., Eng, N., Zeigler, M. and Calne, D.B. Treatment of Parkinson's disease with sodium valproate: Clinical, pharmacological, and biochemical observations. Canadian Journal of Neurological Science 1979; 6: 337-343.
-
(1979)
Canadian Journal of Neurological Science
, vol.6
, pp. 337-343
-
-
Nutt, J.1
Williams, A.2
Plotkin, C.3
Eng, N.4
Zeigler, M.5
Calne, D.B.6
-
16
-
-
0018822366
-
Sodium valproate in schizophrenia: Some biochemical correlates
-
Lautin, A., Angrist, B., Stanley, M., Gershon, S., Heckl, K. and Karobath, M. Sodium valproate in schizophrenia: Some biochemical correlates. British Journal of Psychiatry 1980; 137: 240-244.
-
(1980)
British Journal of Psychiatry
, vol.137
, pp. 240-244
-
-
Lautin, A.1
Angrist, B.2
Stanley, M.3
Gershon, S.4
Heckl, K.5
Karobath, M.6
-
17
-
-
0028351099
-
Differential effects of vigabatrin, γ -acetylenic GABA, aminooxyacetic acid, and valproate on levels of various amino acids in rat brain regions and plasma
-
Löscher, W and Hörstermann, D. Differential effects of vigabatrin, γ -acetylenic GABA, aminooxyacetic acid, and valproate on levels of various amino acids in rat brain regions and plasma. Naunyn-Schmiedeberg's Archives of Pharmacology 1994; 349: 270-278.
-
(1994)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.349
, pp. 270-278
-
-
Löscher, W.1
Hörstermann, D.2
-
18
-
-
0019382422
-
Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiamine in the rat
-
Patsalos, P.N. and Lascelles, P.T. Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiamine in the rat. Journal of Neurochemistry 1981; 36:688-695.
-
(1981)
Journal of Neurochemistry
, vol.36
, pp. 688-695
-
-
Patsalos, P.N.1
Lascelles, P.T.2
-
19
-
-
0024246325
-
Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate, and glutamine in mouse brain cortex
-
Kapetanovic, I.M., Yonekawa, W.D., Torchin, C.D. and Kupferberg, H.J. Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate, and glutamine in mouse brain cortex. Biochemical Pharmacology 1988; 37: 4445-4449.
-
(1988)
Biochemical Pharmacology
, vol.37
, pp. 4445-4449
-
-
Kapetanovic, I.M.1
Yonekawa, W.D.2
Torchin, C.D.3
Kupferberg, H.J.4
-
20
-
-
0025601913
-
Effects of pharmacological manipulation on neurotransmitter and other amino acid levels in the CSF of the senegalese baboon papio papio
-
Valin, A., Voltz, C., Naquet, R. and Lloyd, K.G. Effects of pharmacological manipulation on neurotransmitter and other amino acid levels in the CSF of the senegalese baboon papio papio. Brain Research 1991; 538: 15-23.
-
(1991)
Brain Research
, vol.538
, pp. 15-23
-
-
Valin, A.1
Voltz, C.2
Naquet, R.3
Lloyd, K.G.4
-
24
-
-
0028921973
-
1H spectroscopic measurements of GABA, glutamate, and glutamine in human brain
-
1H spectroscopic measurements of GABA, glutamate, and glutamine in human brain. Epilepsia 1995; 36: 457-464.
-
(1995)
Epilepsia
, vol.36
, pp. 457-464
-
-
Petroff, O.A.C.1
Rothman, D.L.2
Behar, K.L.3
Mattson, R.H.4
-
25
-
-
0031854966
-
Measuring human brain GABA in vivo: Effects of GABA-transaminase inhibition
-
Petroff, O.A.C. and Rothman, D.L. Measuring human brain GABA in vivo: Effects of GABA-transaminase inhibition. Molecular Neurobiology 1998; 16: 97-121.
-
(1998)
Molecular Neurobiology
, vol.16
, pp. 97-121
-
-
Petroff, O.A.C.1
Rothman, D.L.2
-
26
-
-
0027200329
-
Automatic localized in vivo adjustment of all first-and second-order shim coils
-
Gruetter, R. Automatic localized in vivo adjustment of all first-and second-order shim coils. Magnetic Resonance in Medicine 1993; 29: 804-811.
-
(1993)
Magnetic Resonance in Medicine
, vol.29
, pp. 804-811
-
-
Gruetter, R.1
-
28
-
-
0027375098
-
Estimation of metabolite concentrations from localized in vivo NMR spectra
-
Provencher, S.W. Estimation of metabolite concentrations from localized in vivo NMR spectra. Magnetic Resonance in Medicine 1993; 30: 672-679.
-
(1993)
Magnetic Resonance in Medicine
, vol.30
, pp. 672-679
-
-
Provencher, S.W.1
-
30
-
-
0030695043
-
Homocarnosine and the measurement of neuronal pH in patients with epilepsy
-
Rothman, D.L., Behar, K.L., Prichard, J.W. and Petroff, O.A.C. Homocarnosine and the measurement of neuronal pH in patients with epilepsy. Magnetic Resonance in Medicine 1997; 32: 924-929.
-
(1997)
Magnetic Resonance in Medicine
, vol.32
, pp. 924-929
-
-
Rothman, D.L.1
Behar, K.L.2
Prichard, J.W.3
Petroff, O.A.C.4
-
32
-
-
0030052878
-
Initial observations on the effect of gabapentin on brain GABA in patients with epilepsy
-
Petroff, O.A.C., Rothman, D.L., Behar, K.L., Lamoureux, D. and Mattson, R.H. Initial observations on the effect of gabapentin on brain GABA in patients with epilepsy. Annals of Neurology 1996; 39: 95-99.
-
(1996)
Annals of Neurology
, vol.39
, pp. 95-99
-
-
Petroff, O.A.C.1
Rothman, D.L.2
Behar, K.L.3
Lamoureux, D.4
Mattson, R.H.5
-
33
-
-
0029751102
-
Human brain GABA levels rise rapidly following initiation of vigabatrin therapy
-
Petroff, O.A.C., Rothman, D.L., Behar, K.L., Collins, T.L. and Mattson, R.H. human brain GABA levels rise rapidly following initiation of vigabatrin therapy. Neurology 1996; 47: 1567- 1571.
-
(1996)
Neurology
, vol.47
, pp. 1567-1571
-
-
Petroff, O.A.C.1
Rothman, D.L.2
Behar, K.L.3
Collins, T.L.4
Mattson, R.H.5
-
34
-
-
0000436850
-
Human occipital lobe GABA and homocarnosine increased after starting topiramate
-
Petroff, O.A.C., Hyder, R, Rothman, D.L. and Mattson, R.H. Human occipital lobe GABA and homocarnosine increased after starting topiramate. Neurology 1998; 50 (Suppl. 4): A312.
-
(1998)
Neurology
, vol.50
, Issue.SUPPL. 4
-
-
Petroff, O.A.C.1
Hyder, R.2
Rothman, D.L.3
Mattson, R.H.4
-
35
-
-
3042929879
-
GABA levels in the brain: A target for new antiepileptic drugs
-
Kocsis, J.D. and Mattson, R.H. GABA levels in the brain: A target for new antiepileptic drugs. Neuroscientist 1996; 6:326- 334.
-
(1996)
Neuroscientist
, vol.6
, pp. 326-334
-
-
Kocsis, J.D.1
Mattson, R.H.2
-
36
-
-
0001170120
-
Acute and chronic alternations in human cerebral GABA levels in response to topiramate, lamotrigine, and gabapentin
-
Berkeley, International Society of Magnetic Resonance in Medicine
-
Hetherington, H.P., Kuzniecky, R.I. and Pan, J.W. Acute and chronic alternations in human cerebral GABA levels in response to topiramate, lamotrigine, and gabapentin. In: Proceedings of the International Society of Magnetic Resonance in Medicine, Vol. 1. Berkeley, International Society of Magnetic Resonance in Medicine, 1998: p. 542.
-
(1998)
Proceedings of the International Society of Magnetic Resonance in Medicine, Vol. 1
, vol.1
, pp. 542
-
-
Hetherington, H.P.1
Kuzniecky, R.I.2
Pan, J.W.3
-
38
-
-
0027209260
-
15n n.m.r. Measurement of the in vivo rate of glutamine synthesis and utilization at steady state in the brain of the hyperammonaemic rat
-
15n n.m.r. Measurement of the in vivo rate of glutamine synthesis and utilization at steady state in the brain of the hyperammonaemic rat. Biochemical Journal 1993; 293: 461-468.
-
(1993)
Biochemical Journal
, vol.293
, pp. 461-468
-
-
Kanamori, K.1
Ross, B.D.2
-
40
-
-
0002118926
-
Valproic acid toxicity
-
Eds R.H. Levy, R.H. Mattson and B.S. Meldrum. New York, Raven Press
-
th Edition (Eds R.H. Levy, R.H. Mattson and B.S. Meldrum). New York, Raven Press, 1995: pp. 641-648.
-
(1995)
th Edition
, pp. 641-648
-
-
Dreifuss, F.E.1
-
41
-
-
0020616408
-
The renal origin of sodium valproate-induced hyperammonemia in fasting humans
-
Warter, J.M., Brandt, C., Marescaux, C. et al. The renal origin of sodium valproate-induced hyperammonemia in fasting humans. Neurology 1983; 33: 1136-1140.
-
(1983)
Neurology
, vol.33
, pp. 1136-1140
-
-
Warter, J.M.1
Brandt, C.2
Marescaux, C.3
-
43
-
-
0026723977
-
Heterozygote ornithine transcarbamylase deficiency presenting as symptomatic hyperammonemia during initiation of valproate therapy
-
Honeycutt, D., Callahan, K., Rutledge, L. and Evans, B. Heterozygote ornithine transcarbamylase deficiency presenting as symptomatic hyperammonemia during initiation of valproate therapy. Neurology 1992; 42: 666-668.
-
(1992)
Neurology
, vol.42
, pp. 666-668
-
-
Honeycutt, D.1
Callahan, K.2
Rutledge, L.3
Evans, B.4
-
44
-
-
0017164814
-
Cerebrospinal fluid and plasma glutamine elevation by anticonvulsant drugs: A potential diagnostic and therapeutic trap
-
Perry, T.L., Hansen, S. and Maclean, J. Cerebrospinal fluid and plasma glutamine elevation by anticonvulsant drugs: A potential diagnostic and therapeutic trap. Clinica Chimica Acta 1976; 69: 441-445.
-
(1976)
Clinica Chimica Acta
, vol.69
, pp. 441-445
-
-
Perry, T.L.1
Hansen, S.2
Maclean, J.3
-
45
-
-
0022568428
-
Amino acid and catecholamine markers of metabolic abnormalities in human focal epilepsy
-
Sherwin, A.L., van Gelder, N.M. Amino acid and catecholamine markers of metabolic abnormalities in human focal epilepsy. Advances in Neurology 1986; 44: 1011-1032.
-
(1986)
Advances in Neurology
, vol.44
, pp. 1011-1032
-
-
Sherwin, A.L.1
Van Gelder, N.M.2
-
46
-
-
0001461139
-
Cerebral amino acid pools
-
Ed. A. Lajtha. New York, Plenum Press
-
Perry, T. Cerebral amino acid pools. In: Handbook of Neurochemistry (Second Edition) Vol 1. (Ed. A. Lajtha). New York, Plenum Press, 1982: pp 151-180.
-
(1982)
Handbook of Neurochemistry (Second Edition) Vol 1
, vol.1
, pp. 151-180
-
-
Perry, T.1
-
47
-
-
0029609260
-
Symbiosis between in vivo and in vitro NMR spectroscopy: The creatine, N-acetylaspartate, glutamate, and GABA content of epileptic human brain
-
Petroff, O.A.C., Pleban, L.A. and Spencer, D.D. Symbiosis between in vivo and in vitro NMR spectroscopy: The creatine, N-acetylaspartate, glutamate, and GABA content of epileptic human brain. Magnetic Resonance Imaging 1995; 13: 1197- 1211.
-
(1995)
Magnetic Resonance Imaging
, vol.13
, pp. 1197-1211
-
-
Petroff, O.A.C.1
Pleban, L.A.2
Spencer, D.D.3
-
48
-
-
0031116041
-
GABA and epileptogenesis
-
Olsen, R.W. and Avoli, M. GABA and epileptogenesis. Epilepsia 1997; 38: 399-407.
-
(1997)
Epilepsia
, vol.38
, pp. 399-407
-
-
Olsen, R.W.1
Avoli, M.2
-
49
-
-
0026544324
-
Metabolic compartmentation of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum
-
Ottersen, O.P., Zhang, N. and Walberg, F. Metabolic compartmentation of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum. Neuroscience 1992; 46: 519-534.
-
(1992)
Neuroscience
, vol.46
, pp. 519-534
-
-
Ottersen, O.P.1
Zhang, N.2
Walberg, F.3
-
50
-
-
0028310347
-
Glutamate immunoreactivity in rate cerebral cortex is reversibly abolished by 6-diazo-5-oxo-l- norleucine (DON), an inhibitor of phosphate-activated glutaminase
-
Conti, F. and Minelli, A. Glutamate immunoreactivity in rate cerebral cortex is reversibly abolished by 6-diazo-5-oxo-l- norleucine (DON), an inhibitor of phosphate-activated glutaminase. Journal of Histochemistry and Cytochemistry 1994; 42: 717-726.
-
(1994)
Journal of Histochemistry and Cytochemistry
, vol.42
, pp. 717-726
-
-
Conti, F.1
Minelli, A.2
-
51
-
-
0029785988
-
Ammonia and glutamine metabolism during liver insufficiency: The role of kidney and brain in interorgan nitrogen exchange
-
Dejong, C.H.C., Deutz, N.E.P. and Soeters, P.B. Ammonia and glutamine metabolism during liver insufficiency: The role of kidney and brain in interorgan nitrogen exchange. Scandinavian Journal of Gastroenteritis 1996; 218: 61-77.
-
(1996)
Scandinavian Journal of Gastroenteritis
, vol.218
, pp. 61-77
-
-
Dejong, C.H.C.1
Deutz, N.E.P.2
Soeters, P.B.3
-
52
-
-
0031914762
-
Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity
-
Sibson, N.R., Dhankhar, A., Mason, G.F., Rothman, D.L. Behar, K.L. and Shulman, R.G. Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity. Proceedings of the National Academy of Sciences of the United States of America 1998; 95: 316-321.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 316-321
-
-
Sibson, N.R.1
Dhankhar, A.2
Mason, G.F.3
Rothman, D.L.4
Behar, K.L.5
Shulman, R.G.6
-
53
-
-
0027728744
-
Utilization of glutamine and TCA cycle constituents as precursors for transmitter glutamate and GABA
-
Peng, L., Hertz, L. and Huang, R. et al. Utilization of glutamine and TCA cycle constituents as precursors for transmitter glutamate and GABA. Dev Neurosci 1993; 15: 367-377.
-
(1993)
Dev Neurosci
, vol.15
, pp. 367-377
-
-
Peng, L.1
Hertz, L.2
Huang, R.3
|